SCHEMBL434068

SCHEMBL434068

CCCOC(=O)CC(CC)OC(=O)CC(O)CC

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 2/20 0.35
ALDH1A1 P00352 4/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 2/20 0.31
MAPK1 P28482 2/20 0.31
NAAA Q02083 1/20 0.31
DGKA P23743 1/20 0.31
PRKCE Q02156 1/20 0.30
PRKCQ Q04759 1/20 0.30
PRKCD Q05655 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5810650 0.88 ALDH1A1 (0.38) ALDH1A1L3MBTL1LMNAMAPTMAPK1
SCHEMBL9744320 0.88 ALDH1A1 (0.38) ALDH1A1L3MBTL1LMNAMAPTMAPK1
SCHEMBL9743191 0.84 NAAA (0.41) PRKCAALDH1A1L3MBTL1LMNAMAPT
SCHEMBL9743328 0.83 ALDH1A1 (0.41) PRKCAALDH1A1LMNAMAPTMAPK1
SCHEMBL9743223 0.83 ALDH1A1 (0.41) PRKCAALDH1A1LMNAMAPTMAPK1
SCHEMBL9742799 0.81 PRKCA (0.41) PRKCAALDH1A1LMNAMAPTNAAA
SCHEMBL13221940 0.80 MAPT (0.41) PRKCAALDH1A1LMNAMAPTMAPK1
SCHEMBL9743208 0.80 LMNA (0.50) PRKCAALDH1A1LMNAMAPTMAPK1
SCHEMBL6155107 0.80 NAAA (0.40) ALDH1A1L3MBTL1LMNAMAPTMAPK1
SCHEMBL904528 0.79 CYP1A2 (0.41) LMNAMAPTMAPK1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230372225-A1 TWO-STAGE MAKEUP METHOD L'OREAL (FR) 2023-11-23 US disclosed
US-11771639-B2 Aqueous composition comprising a cationic cellulosic polymer, an anionic surfactant comprising at least one cationic counterion, a fatty phase and a pigment L'OREAL (FR) 2023-10-03 US disclosed
US-9993400-B2 Cosmetic composition comprising an alkyl phosphate and a fatty alkyl ether of polyethylene glycol, processes therefor and uses thereof L'OREAL (FR) 2018-06-12 US disclosed
US-20180008526-A1 COMPOSITIONS COMPRISING AT LEAST ONE OIL AND AT LEAST ONE POLYESTER L'OREAL (FR) 2018-01-11 US disclosed
US-9808405-B2 Cosmetic composition comprising an alkyl phosphate and a fatty alkyl ether of polyethylene glycol, processes therefor and uses thereof L'OREAL (FR) 2017-11-07 US disclosed
US-20170181938-A1 COSMETIC COMPOSITON COMPRISING AN ALKYL PHOSPHATE AND A FATTY ALKYL ETHER OF POLYETHYLENE GLYCOL, PROCESSES THEREFOR AND USES THEREOF L'OREAL (FR) 2017-06-29 US disclosed
US-9687426-B2 Cosmetic composition comprising an alkyl phosphate and a fatty alkyl ether of polyethylene glycol, processes therefor and uses thereof L'OREAL (FR) 2017-06-27 US disclosed
US-20160199271-A1 COSMETIC COMPOSITION COMPRISING AN ALKYL PHOSPHATE AND A FATTY ALKYL ETHER OF POLYETHYLENE GLYCOL, PROCESSES THEREFOR AND USES THEREOF L'OREAL (FR) 2016-07-14 US disclosed
US-20150174056-A1 COSMETIC COMPOSITION FOR COATING KERATINOUS FIBRES L'OREAL (FR) 2015-06-25 US disclosed
US-8992899-B2 Clean volume mascara compositions comprising at least one film former and at least one silicone elastomer L'OREAL (FR) 2015-03-31 US disclosed
US-20100055062-A1 COSMETIC COMPOSITION COMPRISING A PROLINE DERIVATIVE AND/OR A SALT OF THE SAID DERIVATIVE L'OREAL (FR) 2010-03-04 US disclosed
US-20100031969-A1 EYELASH MAKEUP AND/OR CARE ASSEMBLY L'OREAL (FR) 2010-02-11 US disclosed
US-20090053157-A1 COMPOSITION COMPRISING A SOYBEAN OIL DERIVATIVE AND/OR A SALT THEREOF L'OREAL (FR) 2009-02-26 US disclosed
US-20090016982-A1 COSMETIC COMPOSITION COMPRISING AN ALKYL PHOSPHATE AND A FATTY ALKYL ETHER OF POLYETHYLENE GLYCOL, PROCESSES THEREFOR AND USES THEREOF L'OREAL (FR) 2009-01-15 US disclosed
US-20080299065-A1 COMPOSITION CONTAINING SULFONIC ACID AND/OR SULFURIC ACID COMPOUND L'OREAL (FR) 2008-12-04 US disclosed
US-20080138300-A2 COMPOSITION COSMETIQUE COMPRENANT UN POLYMERE ACRYLIQUE L'OREAL S.A. (FR) 2008-06-12 US disclosed
US-20080124292-A1 for coating the eyelashes; at least one C16-C30 fatty acid and at least one basic amino acid,at least one glutamic acid compound and/or one of its salts, at least one sarcosine compound L'OREAL (FR) 2008-05-29 US disclosed
US-20080124291-A1 mascara; not only the waxes but also the pigments are homogeneously dispersed; charging make-up for the eyelashes and a satisfactory consistency compatible with producing a smooth and homogeneous deposited layer L'OREAL (FR) 2008-05-29 US disclosed
US-20070256700-A1 Eyelash makeup kit and process therefor L'OREAL S.A. (FR) 2007-11-08 US disclosed
US-20070246058-A1 Makeup and/or care kit L'OREAL (FR) 2007-10-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100055062-A1 COSMETIC COMPOSITION COMPRISING A PROLINE DERIVATIVE AND/OR A SALT OF THE SAID DERIVATIVE EYA3, EYA2, MITF PRKCA 2462/4885ALDH1A1 2254/4885L3MBTL1 4548/4885
US-20150174056-A1 COSMETIC COMPOSITION FOR COATING KERATINOUS FIBRES KRT18, CUTA, DSG1 PRKCA 1024/4885ALDH1A1 2798/4885L3MBTL1 4536/4885
US-20180008526-A1 COMPOSITIONS COMPRISING AT LEAST ONE OIL AND AT LEAST ONE POLYESTER KRT18, DSG1, CUTA PRKCA 885/4885ALDH1A1 3533/4885L3MBTL1 4251/4885
US-20100031969-A1 EYELASH MAKEUP AND/OR CARE ASSEMBLY KRT18, FLNA, F7 PRKCA 368/4885ALDH1A1 4379/4885L3MBTL1 4403/4885
US-20170181938-A1 COSMETIC COMPOSITON COMPRISING AN ALKYL PHOSPHATE AND A FATTY ALKYL ETHER OF POLYETHYLENE GLYCOL, PROCESSES THEREFOR AND USES THEREOF PLIN3, CUTA, PSAP PRKCA 2497/4885ALDH1A1 3885/4885L3MBTL1 2653/4885
US-11771639-B2 Aqueous composition comprising a cationic cellulosic polymer, an anionic surfactant comprising at least one cationic counterion, a fatty phase and a pigment KRT18, CUTA, DSC1 PRKCA 18/4885ALDH1A1 3943/4885L3MBTL1 4830/4885
US-20160199271-A1 COSMETIC COMPOSITION COMPRISING AN ALKYL PHOSPHATE AND A FATTY ALKYL ETHER OF POLYETHYLENE GLYCOL, PROCESSES THEREFOR AND USES THEREOF PHOSPHO1, EYA3, TMEM41B PRKCA 2620/4885ALDH1A1 3510/4885L3MBTL1 2855/4885
US-20090053157-A1 COMPOSITION COMPRISING A SOYBEAN OIL DERIVATIVE AND/OR A SALT THEREOF CEL, STAT6, JAK2 PRKCA 1135/4885ALDH1A1 4727/4885L3MBTL1 3957/4885
US-20080124292-A1 for coating the eyelashes; at least one C16-C30 fatty acid and at least one basic amino acid,at least one glutamic acid compound and/or one of its salts, at least one sarcosine compound S100A10, SGMS1, ACBD3 PRKCA 2006/4885ALDH1A1 4010/4885L3MBTL1 3538/4885
US-20090016982-A1 COSMETIC COMPOSITION COMPRISING AN ALKYL PHOSPHATE AND A FATTY ALKYL ETHER OF POLYETHYLENE GLYCOL, PROCESSES THEREFOR AND USES THEREOF KRT18, CUTA, PHOSPHO1 PRKCA 386/4885ALDH1A1 4068/4885L3MBTL1 3971/4885
US-20080299065-A1 COMPOSITION CONTAINING SULFONIC ACID AND/OR SULFURIC ACID COMPOUND STS, MPST, TST PRKCA 1694/4885ALDH1A1 3225/4885L3MBTL1 4708/4885
US-20230372225-A1 TWO-STAGE MAKEUP METHOD KRT18, DSG1, F12 PRKCA 101/4885ALDH1A1 2388/4885L3MBTL1 4262/4885
US-20080138300-A2 COMPOSITION COSMETIQUE COMPRENANT UN POLYMERE ACRYLIQUE MCCC2, ACMSD, NOTUM PRKCA 709/4885ALDH1A1 877/4885L3MBTL1 841/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.