Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 known ✓ | O15379 | 1/20 | 0.42 |
| ▸ | GAA known ✓ | P10253 | 4/20 | 0.37 |
| ▸ | HSP90AA1 known ✓ | P07900 | 2/20 | 0.34 |
| ▸ | HSP90AB1 known ✓ | P08238 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 2/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8694604 | 1.00 | EP300 (0.42) | EP300KAT2BKAT8IDO1HDAC3 | |
| Hydrochloric Acid SCHEMBL30445419 | 1.00 | EP300 (0.42) | EP300KAT2BKAT8IDO1HDAC3 | |
| SCHEMBL766115 | 0.97 | EP300 (0.44) | EP300KAT2BKAT8IDO1HDAC3 | |
| SCHEMBL29436299 | 0.97 | EP300 (0.44) | EP300KAT2BKAT8IDO1HDAC3 | |
| Terephthalic Acid SCHEMBL9349893 | 0.80 | TP53 (0.48) | ALOX15HSD17B10TSHRALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11791228 | 0.80 | IDO1 (0.44) | EP300KAT2BKAT8IDO1HDAC3 | |
| SCHEMBL4958689 | 0.79 | ALOX15 (0.39) | EP300KAT2BKAT8IDO1HDAC3 | |
| SCHEMBL632398 | 0.79 | ALDH1A1 (0.42) | EP300KAT2BKAT8IDO1HDAC3 | |
| Hydrochloric Acid SCHEMBL28756357 | 0.78 | ALOX15 (0.40) | EP300KAT2BKAT8IDO1HDAC3 | |
| Hydrochloric Acid SCHEMBL28281094 | 0.78 | ALOX15 (0.40) | EP300KAT2BKAT8IDO1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111925719-B | Fireproof floor coating and preparation method thereof | 润奥(上海)环保科技有限公司 | 2021-11-23 | — | — | CN | claimed |
| CN-109593440-B | Environment-friendly nano graphene terrace material and preparation method thereof | 浙江润奥环保科技有限公司 | 2020-12-22 | — | — | CN | claimed |
| CN-109707138-B | Multilayer-structure antistatic environment-friendly epoxy resin terrace and preparation method thereof | 周志茹 | 2024-04-05 | — | — | CN | disclosed |
| CN-116143640-A | Novel fluorine-containing diamine monomer, preparation method and application thereof in preparation of polyimide | 万华化学集团股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-114563848-A | Impact-resistant protective sleeve for optical cable and preparation method thereof | 李慧 | 2022-05-31 | — | — | CN | disclosed |
| CN-216604975-U | Mixer for preparing 4, 6-diamino resorcinol hydrochloride | 江苏新宇生物科技有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114149177-A | High-strength radiation-proof glass and preparation process thereof | 江苏神盾新材料科技有限公司 | 2022-03-08 | — | — | CN | disclosed |
| CN-111925719-B | Fireproof floor coating and preparation method thereof | 润奥(上海)环保科技有限公司 | 2021-11-23 | — | — | CN | disclosed |
| CN-111153812-B | Preparation method of 4,6-diaminoresorcinol hydrochloride | 爱斯特（成都）生物制药股份有限公司 | 2021-10-22 | — | — | CN | disclosed |
| CN-112759527-A | Phosphate, preparation method and application thereof | 中科金绮新材料科技有限公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-109593440-B | Environment-friendly nano graphene terrace material and preparation method thereof | 浙江润奥环保科技有限公司 | 2020-12-22 | — | — | CN | disclosed |
| CN-111153812-A | Preparation method of 4,6-diaminoresorcinol hydrochloride | 爱斯特（成都）生物制药股份有限公司 | 2020-05-15 | — | — | CN | disclosed |
| CN-110819205-A | Graphene composite impact-resistant anti-static environment-friendly coating material and preparation method thereof | 温州奥源新材料科技有限公司 | 2020-02-21 | — | — | CN | disclosed |
| EP-1541726-B1 | POLYBENZAZOLE FIBER AND USE THEREOF | TOYO BOSEKI (JP) | 2008-10-01 | — | — | EP | disclosed |
| US-7357982-B2 | For cords for reinforcing rubber, sheets and rods for reinforcing cement/concrete, composite materials, sail clothes, ropes, knife proof vests and bullet proof vests; staple fibers, spun yarns, and woven or knitted fabrics; heat resistance as high as a thermal decomposition temperature | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2008-04-15 | — | — | US | disclosed |
| US-20060083923-A1 | For cords for reinforcing rubber, sheets and rods for reinforcing cement/concrete, composite materials, sail clothes, ropes, knife proof vests and bullet proof vests; staple fibers, spun yarns, and woven or knitted fabrics; heat resistance as high as a thermal decomposition temperature | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2006-04-20 | — | — | US | disclosed |
| EP-1541726-A1 | POLYBENZAZOLE FIBER AND USE THEREOF | Toyo Boseki Kabushiki Kaisha (JP) | 2005-06-15 | — | — | EP | disclosed |
| CN-1583752-A | Synthesis of benzoxazole | UNIV HARBIN POLYTECHNIC (CN) | 2005-02-23 | — | — | CN | disclosed |
| US-4229566-A | FLEXIBLE STRONG FILMS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1980-10-21 | — | — | US | disclosed |
| US-4108835-A | Phenylated aromatic heterocyclic polymers | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1978-08-22 | — | — | US | disclosed |