Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.38 |
| ▸ | S1PR1 known ✓ | P21453 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 2/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5092744 | 1.00 | FDPS (0.44) | FDPSDNM1OPRM1SPHK1LMNA | |
| Hydrochloric Acid SCHEMBL5087767 | 1.00 | FDPS (0.44) | FDPSDNM1OPRM1SPHK1LMNA | |
| Hydrochloric Acid SCHEMBL5088507 | 1.00 | FDPS (0.44) | FDPSDNM1OPRM1SPHK1LMNA | |
| Hydrochloric Acid SCHEMBL5086681 | 1.00 | FDPS (0.44) | FDPSDNM1OPRM1SPHK1LMNA | |
| Hydrochloric Acid SCHEMBL5139313 | 1.00 | FDPS (0.44) | FDPSDNM1OPRM1SPHK1LMNA | |
| Hydrochloric Acid SCHEMBL5086974 | 1.00 | FDPS (0.44) | FDPSDNM1OPRM1SPHK1LMNA | |
| Hydrochloric Acid SCHEMBL5084849 | 1.00 | FDPS (0.44) | FDPSDNM1OPRM1SPHK1LMNA | |
| SCHEMBL332122 | 0.98 | FDPS (0.46) | FDPSDNM1OPRM1SPHK1LMNA | |
| SCHEMBL1063202 | 0.98 | FDPS (0.46) | FDPSDNM1OPRM1SPHK1LMNA | |
| SCHEMBL16390875 | 0.98 | FDPS (0.46) | FDPSDNM1OPRM1SPHK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025121285-A1 | PHOSPHINE-PALLADIUM COMPLEX, POLYMERIZATION CATALYST, AND METHOD FOR PRODUCING AROMATIC POLYMER | 日本化学工業株式会社 | 2025-06-12 | — | — | WO | disclosed |
| CN-114605223-B | Method for preparing 2,4, 5-trifluoro-benzyl bromide by using 2,4, 5-trifluoro-benzyl chloride | 浙江永太科技股份有限公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-114605223-A | Method for preparing 2,4, 5-trifluorobenzyl bromide by using 2,4, 5-trifluorobenzyl chloride | 浙江永太科技股份有限公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-109790109-B | Process for preparing 3-alkylthio-2-chloro-N- (1-alkyl-1H-tetrazol-5-yl) -4-trifluoromethylbenzamides | 拜耳作物科学股份公司 | 2021-10-22 | — | — | CN | disclosed |
| US-10633321-B2 | Method for producing cyclopropyl-substituted acetophenones | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-04-28 | — | — | US | disclosed |
| US-10457651-B2 | Method for producing 3-alkylsulfanyl-2-chloro-N-(1-alkyl-1H-tetrazol-5-yl)-4-trifluoromethyl-benzamides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-10-29 | — | — | US | disclosed |
| US-10435352-B2 | Method for synthesizing 2-alkyl-4-trifluoromethyl-3-alkylsulfonylbenzoic acids | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-10-08 | — | — | US | disclosed |
| EP-3523270-A1 | METHOD FOR PRODUCING CYCLOPROPYL-SUBSTITUTED ACETOPHENONES | Bayer CropScience Aktiengesellschaft (DE) | 2019-08-14 | — | — | EP | disclosed |
| US-20190233382-A1 | METHOD FOR PRODUCING 3-ALKYLSULFANYL-2-CHLORO-N-(1-ALKYL-1H-TETRAZOL-5-YL)-4-TRIFLUOROMETHYL-BENZAMIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-08-01 | — | — | US | disclosed |
| US-20180305302-A1 | METHOD FOR SYNTHESIZING 2-ALKYL-4-TRIFLUOROMETHYL-3-ALKYLSULFONYLBENZOIC ACIDS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-10-25 | — | — | US | disclosed |
| EP-3368510-A1 | METHOD FOR SYNTHESIZING 2-ALKYL-4-TRIFLUOROMETHYL-3-ALKYLSULFONYLBENZOIC ACIDS | Bayer CropScience Aktiengesellschaft (DE) | 2018-09-05 | — | — | EP | disclosed |
| US-20080214386-A1 | Stability; easily separated from solution; surface treatment of catalyst with Group seven compound; reacting epoxide with carbon dioxide | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2008-09-04 | — | — | US | disclosed |
| US-6806371-B2 | BY MEANS OF PHASE TRANSFER CATALYSIS | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2004-10-19 | — | — | US | disclosed |
| US-20040063957-A1 | Preparation of substituted pyridine N-oxide compounds | DSM FINE CHEMICALS AUSTRIA NFG GMBH & COKG (AT) | 2004-04-01 | — | — | US | disclosed |
| US-5329053-A | Process for the manufacture of known odorants | GIVAUDAN-ROURE CORPORATION (US) | 1994-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180305302-A1 | METHOD FOR SYNTHESIZING 2-ALKYL-4-TRIFLUOROMETHYL-3-ALKYLSULFONYLBENZOIC ACIDS | ARSA, ABL1, CYP2B6 | OPRM1 3980/4885S1PR1 2692/4885FDPS 103/4885 |
| US-10633321-B2 | Method for producing cyclopropyl-substituted acetophenones | CYP21A2, CYP17A1, HSD17B7 | OPRM1 3225/4885S1PR1 4245/4885FDPS 78/4885 |
| US-10457651-B2 | Method for producing 3-alkylsulfanyl-2-chloro-N-(1-alkyl-1H-tetrazol-5-yl)-4-trifluoromethyl-benzamides | CBR3, CBR1, CPS1 | OPRM1 1340/4885S1PR1 1770/4885FDPS 1211/4885 |
| US-20190233382-A1 | METHOD FOR PRODUCING 3-ALKYLSULFANYL-2-CHLORO-N-(1-ALKYL-1H-TETRAZOL-5-YL)-4-TRIFLUOROMETHYL-BENZAMIDES | ABL1, CBR3, CTPS2 | OPRM1 2241/4885S1PR1 1377/4885FDPS 416/4885 |
| US-20040063957-A1 | Preparation of substituted pyridine N-oxide compounds | HRH2, SCO2, CBR1 | OPRM1 38/4885S1PR1 1403/4885FDPS 2555/4885 |
| US-10435352-B2 | Method for synthesizing 2-alkyl-4-trifluoromethyl-3-alkylsulfonylbenzoic acids | ARSA, ABL1, CYP2B6 | OPRM1 3980/4885S1PR1 2692/4885FDPS 103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.