SCHEMBL549233

SCHEMBL549233

CC(C)NC(=N)c1ccc(-c2ccc(-c3ccc(C(=N)NC(C)C)cc3)o2)cc1

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 13/20 0.52
PRMT1 Q99873 2/20 0.52
ALDH1A1 P00352 2/20 0.52
TOP1 P11387 1/20 0.52
HPGD P15428 1/20 0.52
CASP1 P29466 1/20 0.52
CASP7 P55210 1/20 0.52
HSD17B10 Q99714 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
TOP2A P11388 3/20 0.50
TOP2B Q02880 3/20 0.50
NPC1 O15118 1/20 0.37
HTT P42858 1/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6411861 0.98 TOP2A (0.53) NQO2PRMT1ALDH1A1TOP1HPGD
SCHEMBL548296 0.83 NQO2 (0.40) NQO2PRMT1ALDH1A1TOP1HPGD
SCHEMBL27631248 0.82 NQO2 (0.45) NQO2PRMT1ALDH1A1TOP1HPGD
SCHEMBL6750097 0.80 NPC1 (0.35) NQO2PRMT1ALDH1A1TOP1HPGD
SCHEMBL6751623 0.79 ALDH1A1 (0.36) NQO2PRMT1ALDH1A1TOP1HPGD
Hydrochloric Acid SCHEMBL5963208 0.79 CYP1A2 (0.43) NQO2PRMT1ALDH1A1HPGDTDP1
Hydrochloric Acid SCHEMBL8696985 0.79 TAAR1 (0.46) ALDH1A1TDP1NPC1RAB9A
SCHEMBL5030536 0.79 HDAC6 (0.53) ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL5027901 0.79 ESR1 (0.45)
SCHEMBL5482696 0.77 NQO2 (0.59) NQO2PRMT1ALDH1A1TOP1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070276020-A1 Dicationic Compounds For Activity Against Trichomonas Vaginalis NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-11-29 US claimed
US-20070099905-A1 Combinations of drugs for the treatment of neoplasms BORISY ALEXIS 2007-05-03 US claimed
EP-1651211-A4 COMBINATION OF DRUGS FOR THE TREATMENT OF NEOPLASMS COMBINATORX INC (US) 2006-11-22 EP claimed
EP-1651211-A2 COMBINATION OF DRUGS FOR THE TREATMENT OF NEOPLASMS Combinatorx, Incorporated (US) 2006-05-03 EP claimed
EP-1545544-A2 COMBINATIONS OF DRUGS FOR THE TREATMENT OF NEOPLASMS Combinatorx, Incorporated (US) 2005-06-29 EP claimed
US-20050080075-A1 Formulations, conjugates, and combinations of drugs for the treatment of neoplasms COMBINATORX, INC. 2005-04-14 US claimed
WO-2005020913-A2 FORMULATIONS, CONJUGATES, AND COMBINATIONS OF DRUGS FOR THE TREATMENT OF NEOPLASMS COMBINATORX, INCORPORATED (US) 2005-03-10 WO claimed
US-20050054708-A1 Combinations of drugs for the treatment of neoplasms COMINATORX, INCORPORATED 2005-03-10 US claimed
WO-2005011572-A2 COMBINATION OF DRUGS FOR THE TREATMENT OF NEOPLASMS COMBINATORX, INCORPORATED (US) 2005-02-10 WO claimed
US-20040116407-A1 Combinations of drugs for the treatment of neoplasms COMBINATORX, INC. 2004-06-17 US claimed
WO-2004006842-A2 COMBINATIONS OF DRUGS FOR THE TREATMENT OF NEOPLASMS COMBINATORX, INCORPORATED (US) 2004-01-22 WO claimed
WO-2004006849-A2 COMBINATIONS OF DRUGS FOR THE TREATMENT OF NEOPLASMS COMBINATORX, INCORPORATED (US) 2004-01-22 WO claimed
EP-0792271-B1 FURAN DERIVATIVES FOR INHIBITING PNEUMOCYSTIS CARINII PNEUMONIA, GIARDIA LAMBLIA AND CRYPTOSPORIDIUM PARVUM UNIV GEORGIA STATE RES FOUND (US) 2002-02-27 EP claimed
JP-3098545-B2 2000-10-16 JP claimed
EP-0792271-A1 FURAN DERIVATIVES FOR INHIBITING PNEUMOCYSTIS CARINII PNEUMONIA, GIARDIA LAMBLIA AND CRYPTOSPORIDIUM PARVUM GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 1997-09-03 EP claimed
EP-0758453-A1 METHOD OF FLUORESCENT DETECTION OF NUCLEIC ACIDS AND CYTOSKELETON ELEMENTS USING BIS-DICATIONIC ARYL FURANS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1997-02-19 EP claimed
US-5602172-A USING A 2,5-DIPHENYLFURAN COMPOUND THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1997-02-11 US claimed
WO-1996015126-A1 FURAN DERIVATIVES FOR INHIBITING PNEUMOCYSTIS CARINII PNEUMONIA, GIARDIA LAMBLIA AND CRYPTOSPORIDIUM PARVUM GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 1996-05-23 WO claimed
WO-1995030901-A1 METHOD OF FLUORESCENT DETECTION OF NUCLEIC ACIDS AND CYTOSKELETON ELEMENTS USING BIS-DICATIONIC ARYL FURANS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1995-11-16 WO claimed
US-12239617-B2 Mono- and di-amidine endo-exonuclease inhibitors and methods for inhibiting endo-exonuclease activity MONTDOREX INC. (CA) 2025-03-04 US disclosed
EP-3724161-B1 MONO- AND DI-AMIDINE ENDO-EXONUCLEASE INHIBITORS AND METHODS FOR INHIBITING ENDO-EXONUCLEASE ACTIVITY MONTDOREX INC (CA) 2025-01-01 EP disclosed
US-20210338607-A1 MONO- AND DI-AMIDINE ENDO-EXONUCLEASE INHIBITORS AND METHODS FOR INHIBITING ENDO-EXONUCLEASE ACTIVITY MONTDOREX INC. (CA) 2021-11-04 US disclosed
US-20200375924-A1 MONO- AND DI-AMIDINE ENDO-EXONUCLEASE INHIBITORS AND METHODS FOR INHIBITING ENDO-EXONUCLEASE ACTIVITY MONTDOREX INC. (CA) 2020-12-03 US disclosed
EP-3724161-A1 MONO- AND DI-AMIDINE ENDO-EXONUCLEASE INHIBITORS AND METHODS FOR INHIBITING ENDO-EXONUCLEASE ACTIVITY Montdorex Inc. (CA) 2020-10-21 EP disclosed
EP-1891013-B1 TETRAHYDROQUINOLINE DERIVATIVES MERCK PATENT GMBH (DE) 2014-07-23 EP disclosed
US-8524732-B2 Substituted tetrahydroquinolines MERCK PATENT GMBH (DE) 2013-09-03 US disclosed
EP-2121700-B1 SUBSTITUTED TETRAHYDROQUINOLINES MERCK PATENT GMBH (DE) 2012-10-03 EP disclosed
US-8207345-B2 Antitumor agents; use in combination with other drugs such as pentamidine MERCK PATENT GMBH (DE) 2012-06-26 US disclosed
US-20120130147-A1 METHODS FOR THE TREATMENT OF TUMORS WITH INDANE COMPOUNDS FINSINGER DIRK (DE) 2012-05-24 US disclosed
US-8110583-B2 treatment of tumors; 1,5-bis(4'-(N-hydroxyamidino)phenoxy)pentane; maintain cells in the G2/M cell cycle MERCK PATENT GMBH (DE) 2012-02-07 US disclosed
EP-2033959-B1 Tetrahydropyranoquinoline derivatives MERCK PATENT GMBH (DE) 2011-04-27 EP disclosed
US-7915416-B2 Tetrahydroquinolines MERCK PATENT GMBH (DE) 2011-03-29 US disclosed
US-7893082-B2 Antitumor agents; anticancer agents MERCK PATENT GMBH (DE) 2011-02-22 US disclosed
US-7875614-B2 compounds for treatment of tumors MERCK PATENT GMBH (DE) 2011-01-25 US disclosed
US-7868172-B2 2-(hetero)-aryl substituted tetrahydroquinoline derivatives MERCK PATENT GMBH (DE) 2011-01-11 US disclosed
EP-1891011-B1 TETRAHYDROQUINOLINES USED IN THE FORM OF MODULATORS OF MITOTIC MOTOR-PROTEINS EG5 MERCK PATENT GMBH (DE) 2010-12-08 EP disclosed
US-20100120818-A1 SUBSTITUTED TETRAHYDROPYRROLOQUINOLINES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2010-05-13 US disclosed
US-20100076012-A1 TETRAHYDROQUINOLINE DERIVATIVES AND THE USE THEREOF FOR THE TREATMENT OF CANCER MERCK PATENT GMBH (DE) 2010-03-25 US disclosed
US-20100022530-A1 TETRAHYDROBENZOISOXAZOLE AND TETRAHYDROINDAZOLE DERIVATIVES AS MODULATORS OF THE MITOTIC MOTOR PROTEIN MERCK PATENT GMBH (DE) 2010-01-28 US disclosed
US-20100022579-A1 SUBSTITUTED TETRAHYDROQUINOLINES Merck Patent Gesellschaft mit bescrankter Haftung (DE) 2010-01-28 US disclosed
EP-2121700-A1 SUBSTITUTED TETRAHYDROQUINOLINES Merck Patent GmbH (DE) 2009-11-25 EP disclosed
EP-2121706-A1 TETRAHYDROQUINOLINE DERIVATIVES AND USE OF SAME FOR TREATING CANCER Merck Patent GmbH (DE) 2009-11-25 EP disclosed
EP-2121684-A1 SUBSTITUTED TETRAHYDROPYRROLOQUINOLINES Merck Patent GmbH (DE) 2009-11-25 EP disclosed
EP-2104664-A1 TETRAHYDROBENZOISOXAZOLE - AND TETRAHYDROINDAZOLE DERIVATIVES AS MODULATORS OF THE MITOTIC MOTOR PROTEIN Merck Patent GmbH (DE) 2009-09-30 EP disclosed
US-20090118267-A1 INDANES MERCK PATENT GMBH (DE) 2009-05-07 US disclosed
EP-2033959-A1 Tetrahydropyranoquinoline derivatives Merck Patent GmbH (DE) 2009-03-11 EP disclosed
US-20090030028-A1 Tetrahydroquinolines MERCK PATENT GMBH (DE) 2009-01-29 US disclosed
EP-1761515-B1 2-(HETERO-)ARYL SUBSTITUTED TETRAHYDROQUINOLINE DERIVATIVES MERCK PATENT GMBH (DE) 2008-11-05 EP disclosed
WO-2008113452-A1 SUBSTITUTED TETRAHYDROPYRROLOQUINOLINES MERCK PATENT GMBH (DE) 2008-09-25 WO disclosed
WO-2008113451-A1 SUBSTITUTED TETRAHYDROQUINOLINES MERCK PATENT GMBH (DE) 2008-09-25 WO disclosed
WO-2008113456-A1 TETRAHYDROQUINOLINE DERIVATIVES AND USE OF SAME FOR TREATING CANCER MERCK PATENT GMBH (DE) 2008-09-25 WO disclosed
US-20080234299-A1 Quinazolinones MERCK PATENT GMBH (DE) 2008-09-25 US disclosed
US-20080221118-A1 treatment of tumors; 1,5-bis(4'-(N-hydroxyamidino)phenoxy)pentane; maintain cells in the G2/M cell cycle MERCK PATENT GMBH (DE) 2008-09-11 US disclosed
US-20080200451-A1 Tetrahydroquinolines for Use as Modulators of the Mitotic Motor Protein Eg5 MERCK PATENT GMBH (DE) 2008-08-21 US disclosed
US-20080194569-A1 Phthalazinones MERCK PATENT GMBH (DE) 2008-08-14 US disclosed
US-20080194615-A1 Antitumor agents; anticancer agents MERCK PATENT GMBH (DE) 2008-08-14 US disclosed
WO-2008080455-A1 TETRAHYDROBENZOISOXAZOLE - AND TETRAHYDROINDAZOLE DERIVATIVES AS MODULATORS OF THE MITOTIC MOTOR PROTEIN MERCK PATENT GMBH (DE) 2008-07-10 WO disclosed
EP-1891076-A1 SUBSTITUTED TETRAHYDROQUINOLINES Merck Patent GmbH (DE) 2008-02-27 EP disclosed
EP-1891013-A1 TETRAHYDROQUINOLINE DERIVATIVES Merck Patent GmbH (DE) 2008-02-27 EP disclosed
EP-1891011-A1 TETRAHYDROQUINOLINES USED IN THE FORM OF MODULATORS OF MITOTIC MOTOR-PROTEINS EG5 Merck Patent GmbH (DE) 2008-02-27 EP disclosed
EP-1885702-A2 QUINAZOLINONES Merck Patent GmbH (DE) 2008-02-13 EP disclosed
US-20070299043-A1 Anti-scarring drug combinations and use thereof HUNTER WILLIAM L 2007-12-27 US disclosed
US-20070276020-A1 Dicationic Compounds For Activity Against Trichomonas Vaginalis NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-11-29 US disclosed
EP-1858860-A1 PHTHALAZINONES Merck Patent GmbH (DE) 2007-11-28 EP disclosed
US-20070219246-A1 Dihydrobenzothiophenes MERCK PATENT GMBH (DE) 2007-09-20 US disclosed
US-20070208134-A1 Anti-scarring drug combinations and use thereof HUNTER WILLIAM L 2007-09-06 US disclosed
US-20070203167-A1 2-(Hetero)-aryl substituted tetrahydrochinoline MERCK PATENT GMBH (DE) 2007-08-30 US disclosed
US-20070196421-A1 Soft tissue implants and drug combination compositions, and use thereof ANGIOTECH INTERNATIONAL AG (CH) 2007-08-23 US disclosed
US-20070198063-A1 Electrical devices and anti-scarring drug combinations HUNTER WILLIAM L 2007-08-23 US disclosed
US-20070197957-A1 Implantable sensors, implantable pumps and anti-scarring drug combinations HUNTER WILLIAM L 2007-08-23 US disclosed
WO-2007041677-A9 SOFT TISSUE IMPLANTS AND DRUG COMBINATION COMPOSITIONS, AND USE THEREOF COMBINATORX INC (US) 2007-05-31 WO disclosed
WO-2007054138-A1 SUBSTITUTED TETRAHYDROQUINOLINES MERCK PATENT GMBH (DE) 2007-05-18 WO disclosed
US-20070099905-A1 Combinations of drugs for the treatment of neoplasms BORISY ALEXIS 2007-05-03 US disclosed
EP-1778694-A1 TETRAHYDROQUINOLINES Merck Patent GmbH (DE) 2007-05-02 EP disclosed
WO-2007041463-A2 ELECTRICAL DEVICES AND ANTI-SCARRING DRUG COMBINATIONS COMBINATORX, INCORPORATED (US) 2007-04-12 WO disclosed
WO-2007041593-A2 ANTI-SCARRING DRUG COMBINATIONS AND USE THEREOF COMBINATORX, INCORPORATED (US) 2007-04-12 WO disclosed
WO-2007041677-A2 SOFT TISSUE IMPLANTS AND DRUG COMBINATION COMPOSITIONS, AND USE THEREOF COMBINATORX, INCORPORATED (US) 2007-04-12 WO disclosed
WO-2007041584-A2 IMPLANTABLE SENSORS, IMPLANTABLE PUMPS, AND ANTI-SCARRING DRUG COMBINATIONS COMBINATORX, INCORPORATED (US) 2007-04-12 WO disclosed
EP-1761515-A1 2-(HETERO-)ARYL SUBSTITUTED TETRAHYDROQUINOLINE DERIVATIVES MERCK PATENT GmbH (DE) 2007-03-14 EP disclosed
EP-1747214-A2 DIHYDROBENZOTHIOPHENES MERCK PATENT GmbH (DE) 2007-01-31 EP disclosed
US-20070021483-A1 Amidine derivatives for treating amyloidosis NEUROCHEM (INTERNATIONAL) LIMITED (CH) 2007-01-25 US disclosed
US-20070021483-A1 Amidine derivatives for treating amyloidosis NEUROCHEM (INTERNATIONAL) LIMITED (CH) 2007-01-25 US disclosed
WO-2006133805-A1 TETRAHYDROQUINOLINE DERIVATIVES MERCK PATENT GMBH (DE) 2006-12-21 WO disclosed
WO-2006133821-A1 TETRAHYDROQUINOLINES USED IN THE FORM OF MODULATORS OF MITOTIC MOTOR-PROTEINS EG5 MERCK PATENT GMBH (DE) 2006-12-21 WO disclosed
WO-2006125555-A2 QUINAZOLINONES MERCK PATENT GMBH (DE) 2006-11-30 WO disclosed
EP-1651211-A4 COMBINATION OF DRUGS FOR THE TREATMENT OF NEOPLASMS COMBINATORX INC (US) 2006-11-22 EP disclosed
WO-2006097176-A1 PHTHALAZINONES MERCK PATENT GMBH (DE) 2006-09-21 WO disclosed
EP-1670477-A2 COMBINATIONS OF DRUGS FOR THE TREATMENT OF NEOPLASMS CombinatoRx, Incorporated (US) 2006-06-21 EP disclosed
EP-1651211-A2 COMBINATION OF DRUGS FOR THE TREATMENT OF NEOPLASMS Combinatorx, Incorporated (US) 2006-05-03 EP disclosed
WO-2006002726-A1 TETRAHYDROQUINOLINES MERCK PATENT GMBH (DE) 2006-01-12 WO disclosed
WO-2005108355-A2 DIHYDROBENZOTHIOPHENES MERCK PATENT GMBH (DE) 2005-11-17 WO disclosed
WO-2005063735-A1 2-(HETERO)-ARYL-SUBSTITUTED TETRAHYDROQUINOLINE DERIVATIVES MERCK PATENT GMBH (DE) 2005-07-14 WO disclosed
EP-1545544-A2 COMBINATIONS OF DRUGS FOR THE TREATMENT OF NEOPLASMS Combinatorx, Incorporated (US) 2005-06-29 EP disclosed
US-20050137185-A1 Combinations of drugs for the treatment of neoplasms COMBINATORX, INCORPORATED 2005-06-23 US disclosed
US-20050080075-A1 Formulations, conjugates, and combinations of drugs for the treatment of neoplasms COMBINATORX, INC. 2005-04-14 US disclosed
WO-2005027842-A2 COMBINATIONS OF DRUGS FOR THE TREATMENT OF NEOPLASMS COMBINATORX, INCORPORATED (US) 2005-03-31 WO disclosed
WO-2005020913-A2 FORMULATIONS, CONJUGATES, AND COMBINATIONS OF DRUGS FOR THE TREATMENT OF NEOPLASMS COMBINATORX, INCORPORATED (US) 2005-03-10 WO disclosed
US-20050054708-A1 Combinations of drugs for the treatment of neoplasms COMINATORX, INCORPORATED 2005-03-10 US disclosed
WO-2005011572-A2 COMBINATION OF DRUGS FOR THE TREATMENT OF NEOPLASMS COMBINATORX, INCORPORATED (US) 2005-02-10 WO disclosed
US-20040116407-A1 Combinations of drugs for the treatment of neoplasms COMBINATORX, INC. 2004-06-17 US disclosed
WO-2004006842-A2 COMBINATIONS OF DRUGS FOR THE TREATMENT OF NEOPLASMS COMBINATORX, INCORPORATED (US) 2004-01-22 WO disclosed
WO-2004006849-A2 COMBINATIONS OF DRUGS FOR THE TREATMENT OF NEOPLASMS COMBINATORX, INCORPORATED (US) 2004-01-22 WO disclosed
WO-2004002430-A2 COMBINATIONS FOR THE TREATMENT OF FUNGAL INFECTIONS COMBINATORX INCORPORATED (US) 2004-01-08 WO disclosed
EP-0792271-B1 FURAN DERIVATIVES FOR INHIBITING PNEUMOCYSTIS CARINII PNEUMONIA, GIARDIA LAMBLIA AND CRYPTOSPORIDIUM PARVUM UNIV GEORGIA STATE RES FOUND (US) 2002-02-27 EP disclosed
US-5667975-A Method of fluorescent detection of nucleic acids and cytoskeleton elements using bis-dicationic aryl furans THE UNIVERSITY OF NORTH CAROLINA 1997-09-16 US disclosed
CN-1151209-A Method for detecting nucleic acid and cytoskeleton components by using double-dicationic aryl furan fluorescence UNIV NORTH CAROLINA CHAPEL HILL (US) 1997-06-04 CN disclosed
EP-0758453-A1 METHOD OF FLUORESCENT DETECTION OF NUCLEIC ACIDS AND CYTOSKELETON ELEMENTS USING BIS-DICATIONIC ARYL FURANS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1997-02-19 EP disclosed
EP-0758453-A1 METHOD OF FLUORESCENT DETECTION OF NUCLEIC ACIDS AND CYTOSKELETON ELEMENTS USING BIS-DICATIONIC ARYL FURANS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1997-02-19 EP disclosed
US-5602172-A USING A 2,5-DIPHENYLFURAN COMPOUND THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1997-02-11 US disclosed
US-5594138-A MEDICAL DIAGNOSIS GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION (US) 1997-01-14 US disclosed
WO-1996040997-A1 METHOD OF FLUORESCENT DETECTION OF NUCLEIC ACIDS AND CYTOSKELETON ELEMENTS USING BIS-DICATIONIC ARYL FURANS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1996-12-19 WO disclosed
WO-1995030901-A1 METHOD OF FLUORESCENT DETECTION OF NUCLEIC ACIDS AND CYTOSKELETON ELEMENTS USING BIS-DICATIONIC ARYL FURANS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1995-11-16 WO disclosed
WO-1995030901-A1 METHOD OF FLUORESCENT DETECTION OF NUCLEIC ACIDS AND CYTOSKELETON ELEMENTS USING BIS-DICATIONIC ARYL FURANS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1995-11-16 WO disclosed
WO-1995030901-A1 METHOD OF FLUORESCENT DETECTION OF NUCLEIC ACIDS AND CYTOSKELETON ELEMENTS USING BIS-DICATIONIC ARYL FURANS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1995-11-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (26 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080194569-A1 Phthalazinones RB1, H1-3, H1-2 NQO2 207/4885PRMT1 64/4885ALDH1A1 1304/4885
US-20080200451-A1 Tetrahydroquinolines for Use as Modulators of the Mitotic Motor Protein Eg5 KIF5A, KIF5C, KIF5B NQO2 401/4885PRMT1 721/4885ALDH1A1 3886/4885
US-20120130147-A1 METHODS FOR THE TREATMENT OF TUMORS WITH INDANE COMPOUNDS TP53, IDH3A, IDH2 NQO2 20/4885PRMT1 26/4885ALDH1A1 347/4885
US-20050080075-A1 Formulations, conjugates, and combinations of drugs for the treatment of neoplasms ABCB1, SLCO1B3, SLCO1B1 NQO2 667/4885PRMT1 2728/4885ALDH1A1 571/4885
US-12239617-B2 Mono- and di-amidine endo-exonuclease inhibitors and methods for inhibiting endo-exonuclease activity RNASE1, ENDOD1, RNASEL NQO2 450/4885PRMT1 1822/4885ALDH1A1 2266/4885
US-20090118267-A1 INDANES IDH3A, CYP1A1, CCNT1 NQO2 19/4885PRMT1 26/4885ALDH1A1 180/4885
US-20200375924-A1 MONO- AND DI-AMIDINE ENDO-EXONUCLEASE INHIBITORS AND METHODS FOR INHIBITING ENDO-EXONUCLEASE ACTIVITY RNASE1, ENDOD1, RNASEL NQO2 461/4885PRMT1 2015/4885ALDH1A1 2351/4885
US-20050137185-A1 Combinations of drugs for the treatment of neoplasms MKI67, DHFR, IL5 NQO2 338/4885PRMT1 2226/4885ALDH1A1 412/4885
US-20210338607-A1 MONO- AND DI-AMIDINE ENDO-EXONUCLEASE INHIBITORS AND METHODS FOR INHIBITING ENDO-EXONUCLEASE ACTIVITY RNASE1, ENDOD1, RNASEL NQO2 450/4885PRMT1 1822/4885ALDH1A1 2266/4885
US-20070099905-A1 Combinations of drugs for the treatment of neoplasms VHL, NRAS, MYC NQO2 132/4885PRMT1 2584/4885ALDH1A1 662/4885
US-20080234299-A1 Quinazolinones H1-3, NDUFS3, CCNT1 NQO2 5/4885PRMT1 22/4885ALDH1A1 1410/4885
US-20100076012-A1 TETRAHYDROQUINOLINE DERIVATIVES AND THE USE THEREOF FOR THE TREATMENT OF CANCER RECQL, NDUFS3, SDHA NQO2 5/4885PRMT1 121/4885ALDH1A1 1759/4885
US-20090030028-A1 Tetrahydroquinolines RECQL, QTRT1, NRAS NQO2 9/4885PRMT1 29/4885ALDH1A1 1192/4885
US-20070203167-A1 2-(Hetero)-aryl substituted tetrahydrochinoline NCOR1, CCNT2, NCOR2 NQO2 449/4885PRMT1 288/4885ALDH1A1 2222/4885
US-20070208134-A1 Anti-scarring drug combinations and use thereof MMP1, COL2A1, COL1A1 NQO2 3516/4885PRMT1 2874/4885ALDH1A1 590/4885
US-20050054708-A1 Combinations of drugs for the treatment of neoplasms TYMP, DPYD, DHFR NQO2 129/4885PRMT1 1095/4885ALDH1A1 1543/4885
US-20080194615-A1 Antitumor agents; anticancer agents RB1, TP53, CCNT1 NQO2 104/4885PRMT1 117/4885ALDH1A1 1144/4885
US-20100022579-A1 SUBSTITUTED TETRAHYDROQUINOLINES RECQL, NDUFS3, TPD52L2 NQO2 7/4885PRMT1 110/4885ALDH1A1 1828/4885
US-20070196421-A1 Soft tissue implants and drug combination compositions, and use thereof COL2A1, MMP1, FN1 NQO2 4396/4885PRMT1 2596/4885ALDH1A1 1623/4885
US-20070219246-A1 Dihydrobenzothiophenes CCNT1, CCNT2, TPT1 NQO2 56/4885PRMT1 286/4885ALDH1A1 232/4885
US-20070276020-A1 Dicationic Compounds For Activity Against Trichomonas Vaginalis CASP12, DLD, HDAC5 NQO2 1046/4885PRMT1 1577/4885ALDH1A1 3778/4885
US-20070299043-A1 Anti-scarring drug combinations and use thereof MMP1, COL2A1, COL1A1 NQO2 3516/4885PRMT1 2874/4885ALDH1A1 590/4885
US-20100120818-A1 SUBSTITUTED TETRAHYDROPYRROLOQUINOLINES TPD52L2, CCNT1, IDH2 NQO2 29/4885PRMT1 15/4885ALDH1A1 794/4885
US-20080221118-A1 treatment of tumors; 1,5-bis(4'-(N-hydroxyamidino)phenoxy)pentane; maintain cells in the G2/M cell cycle CCNE1, CCNA1, CCNT1 NQO2 447/4885PRMT1 515/4885ALDH1A1 1306/4885
US-20100022530-A1 TETRAHYDROBENZOISOXAZOLE AND TETRAHYDROINDAZOLE DERIVATIVES AS MODULATORS OF THE MITOTIC MOTOR PROTEIN CCNB3, TUBB3, CCNB1 NQO2 139/4885PRMT1 1539/4885ALDH1A1 2977/4885
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“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.