Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19387438 | 0.77 | CA2 (0.33) | — | |
| SCHEMBL8962464 | 0.77 | — | — | |
| SCHEMBL14664104 | 0.77 | — | — | |
| SCHEMBL7790012 | 0.75 | ALDH1A1 (0.36) | TSHR | |
| SCHEMBL12234936 | 0.73 | TSHR (0.33) | TSHR | |
| SCHEMBL13449774 | 0.73 | TSHR (0.33) | TSHR | |
| SCHEMBL5493507 | 0.73 | L3MBTL1 (0.32) | TSHR | |
| SCHEMBL2171251 | 0.73 | — | — | |
| SCHEMBL10120248 | 0.73 | TP53 (0.33) | — | |
| SCHEMBL20286469 | 0.73 | TP53 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 208 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119072304-A | Neuroactive steroids for the treatment of CNS related disorders | 萨奇治疗股份有限公司 | 2024-12-03 | — | — | CN | claimed |
| CN-117384259-A | Cell penetrating peptides based on influenza virus M2 proteins | 中国医学科学院基础医学研究所 | 2024-01-12 | — | — | CN | claimed |
| US-20220372355-A1 | METHOD FOR MAKING AGGLOMERATE PARTICLES | MCARDLE JAMES L (US) | 2022-11-24 | — | — | US | claimed |
| CN-116635452-B | Free radically polymerizable crosslinking agent, curable composition, and adhesive therefrom | 3M INNOVATIVE PROPERTIES CO. (US) | 2026-05-26 | — | — | CN | disclosed |
| EP-4291953-B1 | IMPROVED BLEACHING | XETOS AG (DE) | 2026-04-15 | — | — | EP | disclosed |
| US-12600885-B2 | Composition including monomer with a carboxylic acid group, monomer with a hydroxyl group, an alkyl monomer, and crosslinker and related article and method | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2026-04-14 | — | — | US | disclosed |
| US-12595393-B2 | Curable compositions for forming light scattering layers | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2026-04-07 | — | — | US | disclosed |
| US-12552896-B2 | Ionic copolymer, curable membrane precursor composition, membrane composition, and electronic device | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2026-02-17 | — | — | US | disclosed |
| US-12528158-B2 | Abrasive article and method of making the same | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2026-01-20 | — | — | US | disclosed |
| US-20250375084-A1 | NON-SCRATCH ABRASIVE COMPOSITE AND ABRASIVE CLEANING ARTICLE | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2025-12-11 | — | — | US | disclosed |
| EP-4658145-A1 | ABRASIVE ARTICLE | 3M Innovative Properties Company (US) | 2025-12-10 | — | — | EP | disclosed |
| US-20090281099-A1 | SUBSTITUTED PYRAZINONE DERIVATIVES FOR USE AS A MEDICINE | ANDRES-GIL JOSE IGNACIO | 2009-11-12 | — | — | US | disclosed |
| US-7524837-B2 | Benzotriazapinone salts and methods for using same | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-04-28 | — | — | US | disclosed |
| US-7501418-B2 | e.g. 3-[4-(2-Methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-2,5-dioxa-1,7-diaza-dicyclopenta[a,g]naphthalene; serotonine (5-HT) reuptake inhibitor, alpha 2-adrenoceptor antagonist; antidepressant, anxiolytic agent; Parkinson's disease, eating disorders, psychosis, obesity | JANSSEN PHARMACEUTICA, N.V. (BE) | 2009-03-10 | — | — | US | disclosed |
| US-20090023721-A1 | Novel Substituted Tetracyclic Tetrahydrofuran, Pyrrolidine and Tetrahydrothiophene Derivatives and Their Use as a Medicament | MEGENS ANTONIUS ADRIANUS HENDR | 2009-01-22 | — | — | US | disclosed |
| US-7462717-B2 | C6-and C9-substituted chromeno[4,3-c]isoxazoline derivatives and their use as anti-depressants | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-12-09 | — | — | US | disclosed |
| US-20080108599-A1 | Heterocyclic Tetracyclic Tetrahydrofuran Derivatives As 5Ht2 Inhibitors In The Treatment Of Cns Disorders | JANSSEN-CILAG S.A. (ES) | 2008-05-08 | — | — | US | disclosed |
| US-20080096925-A1 | Novel Substituted 4-Phenyl-4[H-Imidazol-2-YL]-Piperidine Derivatived And Their Use As Selective Non-Peptide Delta Opioid Agonists | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-04-24 | — | — | US | disclosed |
| US-7338949-B2 | Mycobacterial inhibitors | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-03-04 | — | — | US | disclosed |
| US-20070179167-A1 | Inhibitors of serine proteases | VERTEX PHARMACEUTICALS INCORPORATED | 2007-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12528158-B2 | Abrasive article and method of making the same | ITGAV, ILK, ITGA2 | TSHR 4182/4885 |
| US-20080108599-A1 | Heterocyclic Tetracyclic Tetrahydrofuran Derivatives As 5Ht2 Inhibitors In The Treatment Of Cns Disorders | HTR2C, HTR2A, TPH2 | TSHR 262/4885 |
| US-20090023721-A1 | Novel Substituted Tetracyclic Tetrahydrofuran, Pyrrolidine and Tetrahydrothiophene Derivatives and Their Use as a Medicament | HTR2C, HTR5A, TPH2 | TSHR 268/4885 |
| US-20090281099-A1 | SUBSTITUTED PYRAZINONE DERIVATIVES FOR USE AS A MEDICINE | ADRA2C, CHRNA5, ADRB2 | TSHR 2130/4885 |
| US-20080096925-A1 | Novel Substituted 4-Phenyl-4[H-Imidazol-2-YL]-Piperidine Derivatived And Their Use As Selective Non-Peptide Delta Opioid Agonists | OPRD1, OPRK1, OPRL1 | TSHR 354/4885 |
| US-12595393-B2 | Curable compositions for forming light scattering layers | CRY2, FLNB, CDH1 | TSHR 2938/4885 |
| US-20070179167-A1 | Inhibitors of serine proteases | PRSS1, PRSS3, PRSS2 | TSHR 4684/4885 |
| US-12552896-B2 | Ionic copolymer, curable membrane precursor composition, membrane composition, and electronic device | VMA21, PLA2G2A, ARCN1 | TSHR 2529/4885 |
| US-12600885-B2 | Composition including monomer with a carboxylic acid group, monomer with a hydroxyl group, an alkyl monomer, and crosslinker and related article and method | RAD51, HACL2, COL2A1 | TSHR 3374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.