Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.33 |
| ▸ | FGF1 known ✓ | P05230 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | DUSP5 | Q16690 | 1/20 | 0.33 |
| ▸ | FABP3 | P05413 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29618435 | 1.00 | SIRT1 (0.40) | SIRT1PRMT1PTPN1AKR1C3AKR1C2 | |
| SCHEMBL11143422 | 0.83 | FABP3 (0.45) | PRMT1AKR1C3AKR1C2FABP3FABP4 | |
| SCHEMBL29389505 | 0.83 | FABP3 (0.45) | PRMT1AKR1C3AKR1C2FABP3FABP4 | |
| SCHEMBL2171636 | 0.76 | GABRA1 (0.42) | LMNAFABP3FABP4FABP5ALDH1A1 | |
| SCHEMBL67964 | 0.72 | ALDH1A1 (0.50) | LMNATDP1MAPTMCOLN3KDM4E | |
| Sulfuric Acid SCHEMBL8078542 | 0.71 | LMNA (0.46) | PTPN1LMNATDP1MAPTDUSP5 | |
| SCHEMBL6733281 | 0.70 | LMNA (0.43) | PTPN1LMNATDP1MAPTDUSP5 | |
| SCHEMBL8406672 | 0.70 | ALDH1A1 (0.48) | LMNATDP1MAPTMCOLN3KDM4E | |
| Sulfuric Acid SCHEMBL8103454 | 0.70 | ALDH1A1 (0.48) | LMNATDP1MAPTMCOLN3KDM4E | |
| SCHEMBL11323820 | 0.70 | FABP3 (0.43) | LMNAMAPTFABP3FABP4FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250366468-A1 | MIXTURES AND COMPOSITIONS COMPRISING 5-FLUORO-4-IMINO-3-METHYL-1-TOSYL-3,4-DIHYDROPYRIMIDIN-2-ONE, AND METHODS OF USE THEREOF | ADAMA MAKHTESHIM LTD. (IL) | 2025-12-04 | — | — | US | disclosed |
| US-20250302034-A1 | LOW DRIFT TANK MIX ADDITIVE FOR LOW, MEDIUM, AND HIGH SPRAY VOLUME APPLICATION | BAYER AKTIENGESELLSCHAFT (DE) | 2025-10-02 | — | — | US | disclosed |
| US-12414559-B2 | Mixtures and compositions comprising 5-fluoro-4-imino-3-methyl-1-tosyl-3,4-dihydropyrimidin-2-one, and methods of use thereof | ADAMA MAKHTESHIM LTD. (IL) | 2025-09-16 | — | — | US | disclosed |
| US-20250275532-A1 | LOW DRIFT AQUEOUS LIQUID FORMULATIONS FOR LOW, MEDIUM, AND HIGH SPRAY VOLUME APPLICATION | BAYER AKTIENGESELLSCHAFT (DE) | 2025-09-04 | — | — | US | disclosed |
| EP-3337318-B1 | OIL-BASED SUSPENSION CONCENTRATES WITH LOW GRAVITATIONAL SEPARATION AND LOW VISCOSITY | BAYER CROPSCIENCE AG (DE) | 2025-07-16 | — | — | EP | disclosed |
| CN-112080083-B | High-efficiency flame-retardant heat-insulating expandable polystyrene and graphite composite material and preparation method thereof | 天津嘉泰伟业化工有限公司 | 2025-03-07 | — | — | CN | disclosed |
| US-20240268387-A1 | AGROCHEMICAL COMPOSITION WITH IMPROVED DRIFT, SPREADING AND RAINFASTNESS PROPERTIES | BAYER AG (DE) | 2024-08-15 | — | — | US | disclosed |
| US-20240268376-A1 | AGROCHEMICAL COMPOSITION WITH IMPROVED DRIFT, SPREADING AND UPTAKE PROPERTIES | BAYER AKTIENGESELLSCHAFT (DE) | 2024-08-15 | — | — | US | disclosed |
| US-20240237649-A1 | CRYSTALLINE FORMS OF 5-FLUORO-4-IMINO-3-METHYL-1-TOSYL-3,4-DIHYDROPYRIMIDIN-2-ONE, AND MIXTURES, COMPOSITIONS AND METHODS OF USE THEREOF | ADAMA MAKHTESHIM LTD. (IL) | 2024-07-18 | — | — | US | disclosed |
| US-20240032532-A1 | AGROCHEMICAL COMPOSITION WITH IMPROVED DRIFT, UPTAKE AND RAINFASTNESS PROPERTIES | BAYER AKTIENGESELLSCHAFT (DE) | 2024-02-01 | — | — | US | disclosed |
| EP-3238540-A1 | TIMED-RELEASE-TYPE GRANULAR AGROCHEMICAL COMPOSITION AND METHOD FOR MANUFACTURING SAME | Bayer CropScience Aktiengesellschaft (DE) | 2017-11-01 | — | — | EP | disclosed |
| CN-105286096-B | Sweat discharge underwear fabric | 浙江剑利美针织服饰有限公司 | 2017-01-25 | — | — | CN | disclosed |
| CN-106121093-A | A kind of agricultural greenhouse body of wall soil property processing technology and agricultural greenhouse body of wall thereof | 兰州博林生态养生苑有限责任公司 | 2016-11-16 | — | — | CN | disclosed |
| CN-105603749-A | Wedding dress fabric | SHANGHAI WANJING TEXTILE SCIENCE & TECH CO LTD | 2016-05-25 | — | — | CN | disclosed |
| CN-105286096-A | Sweat discharge underwear fabric | SHANGHAI WANJING TEXTILE SCIENCE & TECHNOLOGY CO L | 2016-02-03 | — | — | CN | disclosed |
| CN-101208280-A | Fertilizer-compatible composition | BAYER CROPSCIENCE LP (US) | 2008-06-25 | — | — | CN | disclosed |
| EP-1843993-A1 | FERTILIZER-COMPATIBLE COMPOSITION | Bayer Cropscience LP (US) | 2007-10-17 | — | — | EP | disclosed |
| US-20060166939-A1 | Fertilizer-compatible composition | BAYER CROPSCIENCE LP | 2006-07-27 | — | — | US | disclosed |
| WO-2006079079-A1 | FERTILIZER-COMPATIBLE COMPOSITION | BAYER CROPSCIENCE LP (US) | 2006-07-27 | — | — | WO | disclosed |
| US-20060166898-A1 | Fertilizer-compatible composition | BAYER CROPSCIENCE LP | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250366468-A1 | MIXTURES AND COMPOSITIONS COMPRISING 5-FLUORO-4-IMINO-3-METHYL-1-TOSYL-3,4-DIHYDROPYRIMIDIN-2-ONE, AND METHODS OF USE THEREOF | FFAR3, FFAR1, FFAR4 | THRB 2622/4885FGF1 806/4885SIRT1 3134/4885 |
| US-20060166939-A1 | Fertilizer-compatible composition | PPA1, PFAS, PFKFB2 | THRB 3617/4885FGF1 618/4885SIRT1 3930/4885 |
| US-20060166898-A1 | Fertilizer-compatible composition | MYB, PPA1, GFPT1 | THRB 4045/4885FGF1 231/4885SIRT1 4273/4885 |
| US-20240237649-A1 | CRYSTALLINE FORMS OF 5-FLUORO-4-IMINO-3-METHYL-1-TOSYL-3,4-DIHYDROPYRIMIDIN-2-ONE, AND MIXTURES, COMPOSITIONS AND METHODS OF USE THEREOF | NT5C, RCC1, INF2 | THRB 4473/4885FGF1 1571/4885SIRT1 2094/4885 |
| US-12414559-B2 | Mixtures and compositions comprising 5-fluoro-4-imino-3-methyl-1-tosyl-3,4-dihydropyrimidin-2-one, and methods of use thereof | FFAR3, FFAR1, FFAR4 | THRB 2634/4885FGF1 791/4885SIRT1 3175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.