Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 known ✓ | P21728 | 3/20 | 0.59 |
| ▸ | SLC6A2 known ✓ | P23975 | 3/20 | 0.59 |
| ▸ | DRD3 known ✓ | P35462 | 3/20 | 0.59 |
| ▸ | SLC6A3 known ✓ | Q01959 | 3/20 | 0.59 |
| ▸ | GAA known ✓ | P10253 | 2/20 | 0.59 |
| ▸ | ADRA2A known ✓ | P08913 | 2/20 | 0.59 |
| ▸ | DRD2 known ✓ | P14416 | 2/20 | 0.59 |
| ▸ | DRD4 known ✓ | P21917 | 2/20 | 0.59 |
| ▸ | PTGS1 known ✓ | P23219 | 2/20 | 0.58 |
| ▸ | ADRB2 known ✓ | P07550 | 2/20 | 0.55 |
| ▸ | ADRA1A known ✓ | P35348 | 2/20 | 0.55 |
| ▸ | HTR1A known ✓ | P08908 | 1/20 | 0.55 |
| ▸ | ADRA1D known ✓ | P25100 | 1/20 | 0.55 |
| ▸ | ADRA1B known ✓ | P35368 | 1/20 | 0.55 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.53 |
| ▸ | ADRA2B known ✓ | P18089 | 1/20 | 0.53 |
| ▸ | ADRA2C known ✓ | P18825 | 1/20 | 0.53 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.53 |
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.53 |
| ▸ | HRH1 known ✓ | P35367 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30637623 | 0.98 | MAPT (0.68) | MAPTKDM4EALDH1A1LMNABLM | |
| SCHEMBL735617 | 0.98 | MAPT (0.68) | MAPTKDM4EALDH1A1LMNABLM | |
| Bromide SCHEMBL8585786 | 0.96 | MAPT (0.66) | MAPTKDM4EALDH1A1LMNABLM | |
| Phosphoric Acid SCHEMBL15103074 | 0.89 | MAPT (0.58) | MAPTKDM4EALDH1A1LMNABLM | |
| Dopamine SCHEMBL1809112 | 0.85 | KDM4E (0.67) | MAPTKDM4EALDH1A1LMNABLM | |
| SCHEMBL11806768 | 0.83 | DRD1 (0.71) | MAPTKDM4EALDH1A1LMNABLM | |
| SCHEMBL30082728 | 0.83 | MAPT (0.70) | MAPTKDM4EALDH1A1LMNABLM | |
| SCHEMBL30088530 | 0.83 | DRD1 (0.71) | MAPTKDM4EALDH1A1LMNABLM | |
| Deoxiepinephrine SCHEMBL31364234 | 0.82 | MAPT (1.00) | MAPTKDM4EALDH1A1LMNABLM | |
| Deoxiepinephrine SCHEMBL1320882 | 0.82 | MAPT (1.00) | MAPTKDM4EALDH1A1LMNABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110903658-B | Preparation method of low-temperature flexible modified asphalt rubber material | 湖北工业大学 | 2021-11-12 | — | — | CN | claimed |
| CN-110903658-A | Preparation method of low-temperature flexible modified asphalt rubber material | 湖北工业大学 | 2020-03-24 | — | — | CN | claimed |
| CN-118703012-B | Composite membrane suitable for Prussian blue positive electrode material, and preparation method and application thereof | 太仓中科赛诺新能源科技有限公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-118703012-A | Composite membrane suitable for Prussian blue positive electrode material, and preparation method and application thereof | 太仓中科赛诺新能源科技有限公司 | 2024-09-27 | — | — | CN | disclosed |
| CN-110903658-B | Preparation method of low-temperature flexible modified asphalt rubber material | 湖北工业大学 | 2021-11-12 | — | — | CN | disclosed |
| CN-110903658-A | Preparation method of low-temperature flexible modified asphalt rubber material | 湖北工业大学 | 2020-03-24 | — | — | CN | disclosed |
| CN-105017528-B | A kind of preparation method and applications of the polymer containing catechol | 中山大学 | 2018-01-23 | — | — | CN | disclosed |
| EP-1265483-B1 | USE OF PHENYLETHYLAMINE DERIVATIVES FOR THE ANITMICROBIAL TREATMENT OF SURFACES | CIBA SC HOLDING AG (CH) | 2006-03-29 | — | — | EP | disclosed |
| US-6846492-B2 | Use of phenylethylamine derivatives for the antimicrobial treatment of surfaces | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2005-01-25 | — | — | US | disclosed |
| US-20030207884-A1 | Use of phenylethylamine derivatives for the antimicrobial treatment of surfaces | CIBA SPECIALTY CHEMICALS CORP. | 2003-11-06 | — | — | US | disclosed |
| US-5759701-A | INK JET PRINTING | XEROX CORPORATION (US) | 1998-06-02 | — | — | US | disclosed |
| US-5635322-A | Process for developing and overcoating migration imaging members | XEROX CORPORTION (US) | 1997-06-03 | — | — | US | disclosed |
| US-5580689-A | SOLFTENABLE LAYER OF SOFTENABLE MATERIAL, PIGMENT SENSITIVE TO INFRARED OR RED LIGHT ILLUMINATION, AND MIGRATION MARKING MATERIAL | XEROX CORPORATION (US) | 1996-12-03 | — | — | US | disclosed |
| US-5534374-A | Migration imaging members | XEROX CORPORATION (US) | 1996-07-09 | — | — | US | disclosed |
| EP-0673781-A1 | Recording sheets containing amine salts and quaternary choline halides | XEROX CORPORATION (US) | 1995-09-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207884-A1 | Use of phenylethylamine derivatives for the antimicrobial treatment of surfaces | CLTC, TUBA3C, AOC1 | DRD1 2392/4885SLC6A2 4468/4885DRD3 1117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.