Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL689017 | 0.86 | MAPT (0.42) | DRD2DRD1DRD3ELANEAKR1C3 | |
| SCHEMBL18817857 | 0.85 | MAPT (0.41) | DRD2DRD1DRD3ELANEAKR1C3 | |
| SCHEMBL15795285 | 0.81 | ELANE (0.40) | DRD2DRD1DRD3ELANEAKR1C3 | |
| Sulfuric Acid SCHEMBL28055088 | 0.80 | DRD2 (0.52) | DRD2DRD1DRD3ELANEAKR1C3 | |
| SCHEMBL769670 | 0.79 | DRD2 (0.57) | DRD2DRD1DRD3ELANEAKR1C3 | |
| SCHEMBL30149165 | 0.79 | DRD2 (0.57) | DRD2DRD1DRD3ELANEAKR1C3 | |
| SCHEMBL29945615 | 0.78 | DRD2 (0.56) | DRD2DRD1DRD3ELANEAKR1C3 | |
| SCHEMBL1161009 | 0.78 | DRD2 (0.56) | DRD2DRD1DRD3ELANEAKR1C3 | |
| SCHEMBL9411580 | 0.77 | LIG1 (0.46) | AKR1C3KMT2AGAAMAPTSTS | |
| SCHEMBL6063472 | 0.77 | ABCB1 (0.47) | DRD2DRD1DRD3ELANEAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 808 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023032110-A1 | STABILIZED SILVER-ION WATER, STABILIZED SILVER-ION WATER PRODUCTION METHOD, SILVER-ION GEL, AND SILVER-ION DETERGENT | 株式会社クリーンテック販売 | 2023-03-09 | — | — | WO | claimed |
| US-20190099342-A1 | COOLING PRODUCT | SYMRISE AG (DE) | 2019-04-04 | — | — | US | claimed |
| EP-2172185-B1 | Cosmetic material comprising octyl hydroxy stearate oligomer | PARAHERMOSA CO LTD (JP) | 2011-11-23 | — | — | EP | claimed |
| WO-2007110415-A2 | USE OF DIACETYL TRIMERS AND COSMETIC OR THERAPEUTIC FORMULATIONS CONTAINING THESE COMPOUNDS | SYMRISE GMBH & CO. KG (DE) | 2007-10-04 | — | — | WO | claimed |
| JP-7233046-A | — | — | None | — | — | JP | disclosed |
| US-20240237643-A1 | COMPOSITIONS WITH VIRUCIDAL AND/OR ANTIVIRAL ACTIVITY | SYMRISE AG (DE) | 2024-07-18 | — | — | US | disclosed |
| US-12036306-B2 | Cosmetic product | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2024-07-16 | — | — | US | disclosed |
| CN-118302179-A | Cosmetic composition for reducing the oiliness and shine of the skin and use of the same | 欧莱雅 | 2024-07-05 | — | — | CN | disclosed |
| US-20240216248-A1 | MICROBIAL GLYCOLIPIDS | ANALYTICON DISCOVERY GMBH (DE) | 2024-07-04 | — | — | US | disclosed |
| US-20240216272-A1 | PHARMACEUTICAL PREPARATION | KOWA COMPANY, LTD. (JP) | 2024-07-04 | — | — | US | disclosed |
| EP-4391993-A1 | W/O TYPE COMPOSITION COMPRISING ORGANIC UV FILTER AND SPHERICAL HYDROPHOBIC SILICA | L'OREAL (FR) | 2024-07-03 | — | — | EP | disclosed |
| US-12023396-B2 | Flavour and fragrance compositions comprising acetophenone derivatives | SYMRISE AG (DE) | 2024-07-02 | — | — | US | disclosed |
| EP-0887070-A1 | External composition for skin comprising sphingoglycolipid | Kibun Food ChemiFA Co., Ltd. (JP) | 1998-12-30 | — | — | EP | disclosed |
| EP-0882447-A1 | SOLUBLE COSMETICS | SHISEIDO COMPANY LIMITED (JP) | 1998-12-09 | — | — | EP | disclosed |
| US-5750563-A | MIXING A CATECHIN, A FLAVONE, OR A TANNIN INTO EMULSIFIED MIXTURE OF KOJIC ACID, NONIONIC SURFACTANT, AND ULTRAVIOLET LIGHT ABSORBER; STABILIZATION, DISCOLORATION INHIBITION | SANSHO SEIYAKU CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0826365-A2 | Tocopheryl ascorbyl phosphate-cyclodextrin clathrate and a topical dermal composition containing said clathrate | Senju Pharmaceutical Co., Ltd. (JP) | 1998-03-04 | — | — | EP | disclosed |
| US-5637293-A | STABILITY; DISCOLORATION INHIBITION; MIXTURE OF KOJIC ACID, ULTRAVIOLET RADIATION ABSORBER, FATTY ESTER AND(OR) GLYCERIDE | SANSHO SEIYAKU CO., LTD. (JP) | 1997-06-10 | — | — | US | disclosed |
| US-5599528-A | PREVENTING DISCOLORATION AND DECOMPOSITION OF KOJIC ACID IN AQUEOUS COSMETIC EMULSIONS BY ADDING NONIONIC SURFACTANTS AND CONTROLLING HYDROPHILIC-LIPOPHILIC BALANCE | SANSHO SEIYAKU CO., LTD. (JP) | 1997-02-04 | — | — | US | disclosed |
| EP-0689830-A2 | Skin cosmetic composition | Senju Pharmaceutical Co., Ltd. (JP) | 1996-01-03 | — | — | EP | disclosed |
| JP-H07233046-A | EXTERNAL PREPARATION | KOSE CORP | 1995-09-05 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190099342-A1 | COOLING PRODUCT | TRPA1, TRPV2, NISCH | DRD2 2052/4885DRD1 1850/4885DRD3 2596/4885 |
| US-12023396-B2 | Flavour and fragrance compositions comprising acetophenone derivatives | FAAH2, ADH5, NISCH | DRD2 1078/4885DRD1 770/4885DRD3 1267/4885 |
| US-20240216248-A1 | MICROBIAL GLYCOLIPIDS | UGCG, SGMS1, GPR119 | DRD2 1469/4885DRD1 861/4885DRD3 1004/4885 |
| US-20240237643-A1 | COMPOSITIONS WITH VIRUCIDAL AND/OR ANTIVIRAL ACTIVITY | ZC3HAV1, SAMHD1, ZC3HAV1L | DRD2 1560/4885DRD1 1369/4885DRD3 1819/4885 |
| US-20240216272-A1 | PHARMACEUTICAL PREPARATION | SFPQ, HAX1, XDH | DRD2 259/4885DRD1 47/4885DRD3 307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.