Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 5/20 | 0.50 |
| ▸ | CA2 | P00918 | 5/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29068281 | 0.98 | GAA (0.58) | GAAKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL20798298 | 0.84 | CALM1 (0.54) | GAAKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL639120 | 0.84 | POLB (0.57) | GAAKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL51653 | 0.83 | GAA (0.53) | GAAKDM4EMEN1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL28472802 | 0.82 | POLB (0.56) | GAAKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL805304 | 0.82 | MTNR1A (0.55) | GAAKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL1638977 | 0.82 | GAA (0.52) | GAAKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL8959159 | 0.80 | GAA (0.50) | GAAKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL22284793 | 0.80 | GAA (0.50) | GAAKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL21248098 | 0.80 | ALDH1A1 (0.50) | GAAKDM4EMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230364032-A1 | USE OF 2-HOBA TO TREAT ATHEROSCLEROSIS | VANDERBILT UNIVERSITY | 2023-11-16 | — | — | US | disclosed |
| US-20230355549-A1 | METHOD OF PREVENTING KIDNEY INJURY DISRUPTION OF INTESTINAL LYMPHATICS | VANDERBILT UNIVERSITY | 2023-11-09 | — | — | US | disclosed |
| US-20230355549-A1 | METHOD OF PREVENTING KIDNEY INJURY DISRUPTION OF INTESTINAL LYMPHATICS | VANDERBILT UNIVERSITY | 2023-11-09 | — | — | US | disclosed |
| US-20230330049-A1 | COMPOSITIONS AND METHODS OF USE OF GAMMA-KETOALDHEYDE SCAVENGERS FOR TREATING, PREVENTING OR IMPROVING FIBROSIS OF THE LIVER | MTI BIOTECH, INC. | 2023-10-19 | — | — | US | disclosed |
| US-20230330049-A1 | COMPOSITIONS AND METHODS OF USE OF GAMMA-KETOALDHEYDE SCAVENGERS FOR TREATING, PREVENTING OR IMPROVING FIBROSIS OF THE LIVER | MTI BIOTECH, INC. | 2023-10-19 | — | — | US | disclosed |
| CN-116554080-A | 1H-indole-2-carboxylic acid derivative, pharmaceutical composition and application | 深圳市坤健创新药物研究院 | 2023-08-08 | — | — | CN | disclosed |
| US-11696903-B2 | Compounds and methods for scavenging dicarbonyl electrophiles | VANDERBILT UNIVERSITY (US) | 2023-07-11 | — | — | US | disclosed |
| US-20230181494-A1 | COMPOSITIONS AND METHODS OF USE OF GAMMA-KETOALDEHYDE SCAVENGERS FOR TREATING, PREVENTING OR IMPROVING NONALCOHOLIC FATTY LIVER DISEASE (NAFLD), NASH, ALD OR CONDITIONS RELATED TO THE LIVER | MTI BIOTECH, INC. | 2023-06-15 | — | — | US | disclosed |
| US-20230069820-A9 | USE OF 2-HYDROXYBENZYLAMINE FOR THE TREATMENT OF SYSTEMIC LUPUS | VANDERBILT UNIVERSITY | 2023-03-02 | — | — | US | disclosed |
| US-11400103-B2 | Methods of preventing platelet activation | VANDERBILT UNIVERSITY (US) | 2022-08-02 | — | — | US | disclosed |
| WO-2011134444-A9 | SUBSTITUTION DERIVATIVES OF N6-BENZYLADENOSINE-5´-MONOPHOSPHATE, METHODS OF PREPARATION THEREOF, USE THEREOF AS MEDICAMENTS, AND THERAPEUTIC PREPARATION CONTAINING THESE COMPOUNDS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2012-02-16 | — | — | WO | disclosed |
| WO-2011134444-A2 | SUBSTITUTION DERIVATIVES OF N6-BENZYLADENOSINE-5´-MONOPHOSPHATE, METHODS OF PREPARATION THEREOF, USE THEREOF AS MEDICAMENTS, AND THERAPEUTIC PREPARATION CONTAINING THESE COMPOUNDS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2011-11-03 | — | — | WO | disclosed |
| WO-2011008202-A1 | ISOKETAL SCAVENGERS AND MITIGATION OF DISORDERS INVOLVING OXIDATIVE INJURY | VANDERBILT UNIVERSITY (US) | 2011-01-20 | — | — | WO | disclosed |
| EP-1475094-B1 | Pyrazolo[4,3-D]pyrimidines, process for their preparation and methods of use | USTAV EX BOTAN AKADEMIE VED CE (CZ) | 2010-07-28 | — | — | EP | disclosed |
| WO-2008121076-A1 | TITANIUM COMPOUND AND PROCESS FOR ASYMMETRIC CYANATION OF IMINES | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2008-10-09 | — | — | WO | disclosed |
| US-20070167466-A1 | \"Pyrazolo [4,3-d]pyrimidines, processes for their preparation and methods of use\ | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2007-07-19 | — | — | US | disclosed |
| US-20060166925-A1 | Substitution derivatives of n6-benzyladenosine, methods of their preparation, their use for preparation of drugs, cosmetic preparations and growth regulators, pharmaceutical preparations, cosmetic preparations and growth regulators containing these compounds | USTAV EXPERIMENTALNI BOTANIKY AKADEMIE VED CESKE REPUBLIKY (CZ) | 2006-07-27 | — | — | US | disclosed |
| US-20050171049-A1 | Compounds for the treatment of ischemia | DENINNO MICHAEL P (US) | 2005-08-04 | — | — | US | disclosed |
| EP-1475094-A1 | Pyrazolo[4,3-D]pyrimidines, process for their preparation and methods of use | Ustav Experimentalni Botaniky Akademie ved Ceské Republiky (CZ) | 2004-11-10 | — | — | EP | disclosed |
| EP-1241176-A1 | Purine derivatives for the treatment of ischemia | Pfizer Products Inc. (US) | 2002-09-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171049-A1 | Compounds for the treatment of ischemia | TNNI3, ADRB3, TBXA2R | GAA 1485/4885KDM4E 4678/4885MEN1 4557/4885 |
| US-20060166925-A1 | Substitution derivatives of n6-benzyladenosine, methods of their preparation, their use for preparation of drugs, cosmetic preparations and growth regulators, pharmaceutical preparations, cosmetic preparations and growth regulators containing these compounds | ADAR, ADORA2A, AMPD2 | GAA 847/4885KDM4E 292/4885MEN1 1844/4885 |
| US-20230181494-A1 | COMPOSITIONS AND METHODS OF USE OF GAMMA-KETOALDEHYDE SCAVENGERS FOR TREATING, PREVENTING OR IMPROVING NONALCOHOLIC FATTY LIVER DISEASE (NAFLD), NASH, ALD OR CONDITIONS RELATED TO THE LIVER | CPT1A, AKR7A2, FABP1 | GAA 115/4885KDM4E 692/4885MEN1 4823/4885 |
| US-20230364032-A1 | USE OF 2-HOBA TO TREAT ATHEROSCLEROSIS | HACL2, APOB, OAT | GAA 402/4885KDM4E 2385/4885MEN1 2895/4885 |
| US-20230355549-A1 | METHOD OF PREVENTING KIDNEY INJURY DISRUPTION OF INTESTINAL LYMPHATICS | FABP2, SI, MLN | GAA 3064/4885KDM4E 3446/4885MEN1 4644/4885 |
| US-20230330049-A1 | COMPOSITIONS AND METHODS OF USE OF GAMMA-KETOALDHEYDE SCAVENGERS FOR TREATING, PREVENTING OR IMPROVING FIBROSIS OF THE LIVER | GGT1, GGH, AKR7A2 | GAA 256/4885KDM4E 444/4885MEN1 4532/4885 |
| US-20070167466-A1 | \"Pyrazolo [4,3-d]pyrimidines, processes for their preparation and methods of use\ | CBR3, PYM1, PNPO | GAA 4458/4885KDM4E 2102/4885MEN1 4350/4885 |
| US-20230069820-A9 | USE OF 2-HYDROXYBENZYLAMINE FOR THE TREATMENT OF SYSTEMIC LUPUS | SSB, HBG2, INMT | GAA 612/4885KDM4E 449/4885MEN1 2308/4885 |
| US-11400103-B2 | Methods of preventing platelet activation | PLG, PLA2G7, PLAT | GAA 481/4885KDM4E 3590/4885MEN1 4146/4885 |
| US-11696903-B2 | Compounds and methods for scavenging dicarbonyl electrophiles | OGG1, LGMN, GLO1 | GAA 504/4885KDM4E 1923/4885MEN1 1893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.