Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 known ✓ | P11511 | 1/20 | 0.30 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.30 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28249098 | 1.00 | SPHK1 (0.30) | SPHK1CYP19A1LIPGACHEBACE1 | |
| SCHEMBL28256384 | 0.98 | SPHK1 (0.31) | SPHK1CYP19A1LIPGACHEBACE1 | |
| SCHEMBL2907314 | 0.92 | NPC1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL6675000 | 0.76 | PTGS2 (0.34) | CYP19A1LIPGACHEBACE1 | |
| Hydrochloric Acid SCHEMBL8397551 | 0.76 | PTGS2 (0.37) | CYP19A1LIPGACHEBACE1 | |
| Hydrochloric Acid SCHEMBL28064771 | 0.76 | PTGS2 (0.34) | CYP19A1LIPGACHEBACE1 | |
| SCHEMBL6250217 | 0.75 | PTGS2 (0.36) | CYP19A1LIPGACHEBACE1 | |
| SCHEMBL6253058 | 0.73 | PTGS2 (0.38) | CYP19A1LIPGACHEBACE1 | |
| SCHEMBL6250287 | 0.73 | PTGS2 (0.38) | CYP19A1LIPGACHEBACE1 | |
| SCHEMBL6253785 | 0.73 | PTGS2 (0.38) | CYP19A1LIPGACHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2766461-B1 | HIGH EFFICIENCY ENGINE OIL COMPOSITIONS | EXXONMOBIL TECHNOLOGY & ENGINEERING COMPANY (US) | 2023-05-03 | — | — | EP | disclosed |
| EP-2766460-B1 | LOW VISCOSITY ENGINE OIL COMPOSITIONS | EXXONMOBIL TECHNOLOGY & ENGINEERING COMPANY (US) | 2022-07-06 | — | — | EP | disclosed |
| EP-2766459-B1 | LUBRICATING COMPOSITIONS | EXXONMOBIL RES & ENG CO (US) | 2022-01-19 | — | — | EP | disclosed |
| US-11180709-B2 | Functional fluids comprising low-viscosity, low-volatility polyalpha-olefin base stock | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2021-11-23 | — | — | US | disclosed |
| US-20200407657-A1 | Functional Fluids Comprising Low-Viscosity, Low-Volatility Polyalpha-Olefin Base Stock | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2020-12-31 | — | — | US | disclosed |
| EP-2766458-B1 | PROCESS TO PRODUCE POLY ALPHA OLEFIN COMPOSITIONS | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2018-03-28 | — | — | EP | disclosed |
| US-9796645-B2 | Poly alpha olefin compositions | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2017-10-24 | — | — | US | disclosed |
| US-9399746-B2 | Poly alpha olefin compositions | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2016-07-26 | — | — | US | disclosed |
| US-9365788-B2 | Process to produce improved poly alpha olefin compositions | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2016-06-14 | — | — | US | disclosed |
| US-9234152-B2 | High efficiency engine oil compositions | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2016-01-12 | — | — | US | disclosed |
| US-9234150-B2 | Low viscosity engine oil compositions | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2016-01-12 | — | — | US | disclosed |
| US-9234151-B2 | Lubricating compositions | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2016-01-12 | — | — | US | disclosed |
| US-20130253244-A1 | Process to Produce Improved Poly Alpha Olefin Compositions | EXXONMOBIL CHEMICAL PATENTS INC. | 2013-09-26 | — | — | US | disclosed |
| US-20130245344-A1 | Poly Alpha Olefin Compositions | EXXONMOBIL CHEMICAL PATENTS INC. | 2013-09-19 | — | — | US | disclosed |
| US-20130245343-A1 | New Poly Alpha Olefin Compositions | EXXONMOBIL CHEMICAL PATENTS INC. | 2013-09-19 | — | — | US | disclosed |
| US-20130090278-A1 | HIGH EFFICIENCY ENGINE OIL COMPOSITIONS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-04-11 | — | — | US | disclosed |
| US-20130090277-A1 | LUBRICATING COMPOSITIONS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-04-11 | — | — | US | disclosed |
| US-20130090273-A1 | LOW VISCOSITY ENGINE OIL COMPOSITIONS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-04-11 | — | — | US | disclosed |
| US-6977283-B1 | Polymerization process | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2005-12-20 | — | — | US | disclosed |
| EP-1070088-B1 | POLYMERIZATION PROCESS | EXXONMOBIL CHEM PATENTS INC (US) | 2005-06-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130245343-A1 | New Poly Alpha Olefin Compositions | POLK, POLL, HAO2 | CYP19A1 3452/4885ACHE 4547/4885SPHK1 1133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.