Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 4/20 | 0.31 |
| ▸ | ADRB2 known ✓ | P07550 | 1/20 | 0.30 |
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.30 |
| ▸ | DRD4 known ✓ | P21917 | 1/20 | 0.30 |
| ▸ | HTR1D known ✓ | P28221 | 1/20 | 0.30 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.30 |
| ▸ | ADRA1B known ✓ | P35368 | 1/20 | 0.30 |
| ▸ | OPRD1 known ✓ | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 known ✓ | P41145 | 1/20 | 0.30 |
| ▸ | HTR2B known ✓ | P41595 | 1/20 | 0.30 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.30 |
| ▸ | SIGMAR1 known ✓ | Q99720 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | FPR1 | P21462 | 1/20 | 0.30 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
| ▸ | GPR183 | P32249 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL655960 | 0.91 | OPRM1 (0.35) | OPRM1OPRL1MEN1LMNAADRB2 | |
| SCHEMBL654000 | 0.91 | OPRM1 (0.34) | OPRM1OPRL1MEN1LMNAADRB2 | |
| SCHEMBL654271 | 0.90 | CCR1 (0.34) | OPRM1OPRL1CCR1 | |
| SCHEMBL653214 | 0.89 | OPRM1 (0.35) | OPRM1OPRL1MEN1GMNNLMNA | |
| SCHEMBL655073 | 0.84 | CCR1 (0.37) | OPRM1OPRL1MEN1GMNNLMNA | |
| SCHEMBL658798 | 0.84 | CCR1 (0.35) | OPRM1OPRL1MEN1LMNAADRB2 | |
| SCHEMBL654382 | 0.84 | DRD2 (0.35) | OPRM1OPRL1MEN1GMNNLMNA | |
| SCHEMBL655037 | 0.84 | DRD2 (0.38) | OPRM1OPRL1MEN1LMNAADRB2 | |
| SCHEMBL653476 | 0.83 | OPRM1 (0.35) | OPRM1OPRL1MEN1LMNAADRB2 | |
| SCHEMBL655209 | 0.82 | DRD2 (0.34) | OPRM1OPRL1MEN1GMNNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9926478-B2 | Highly durable superhydrophobic, oleophobic and anti-icing coatings and methods and compositions for their preparation | ROSS TECHNOLOGY CORPORATION (US) | 2018-03-27 | — | — | US | disclosed |
| EP-2346678-B1 | SPILL RESISTANT SURFACES HAVING HYDROPHOBIC AND OLEOPHOBIC BORDERS | ROSS TECH CORP (US) | 2017-10-04 | — | — | EP | disclosed |
| US-20170038127-A1 | Spill Resistant Surfaces Having Hydrophobic and Oleophobic Borders | ADT TECHNOLOGY LLC | 2017-02-09 | — | — | US | disclosed |
| US-20160289810-A1 | Highly Durable Superhydrophobic, Oleophobic and Anti-Icing Coatings and Methods and Compositions for Their Preparation | ADT TECHNOLOGY LLC | 2016-10-06 | — | — | US | disclosed |
| US-9243175-B2 | Spill resistant surfaces having hydrophobic and oleophobic borders | ROSS TECHNOLOGY CORPORATION (US) | 2016-01-26 | — | — | US | disclosed |
| US-9096786-B2 | Spill resistant surfaces having hydrophobic and oleophobic borders | ROSS TECHNOLOGY CORPORATION (US) | 2015-08-04 | — | — | US | disclosed |
| US-9067821-B2 | Highly durable superhydrophobic, oleophobic and anti-icing coatings and methods and compositions for their preparation | ROSS TECHNOLOGY CORPORATION (US) | 2015-06-30 | — | — | US | disclosed |
| US-20150097475-A1 | Spill Resistant Surfaces Having Hydrophobic and Oleophobic Borders | SSW ADVANCED TECHNOLOGIES, LLC | 2015-04-09 | — | — | US | disclosed |
| US-20120045954-A1 | HIGHLY DURABLE SUPERHYDROPHOBIC. OLEOPHOBIC AND ANTI-ICING COATINGS AND METHODS AND COMPOSITIONS FOR THEIR PREPARATION | ROSS TECHNOLOGY CORPORATION (US) | 2012-02-23 | — | — | US | disclosed |
| US-20120009396-A1 | SPILL RESISTANT SURFACES HAVING HYDROPHOBIC AND OLEOPHOBIC BORDERS | ROSS TECHNOLOGY CORPORATION (US) | 2012-01-12 | — | — | US | disclosed |
| US-20050070549-A1 | Chemokine receptor antagonists and methods of use thereof | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070549-A1 | Chemokine receptor antagonists and methods of use thereof | ACKR3, CXCR2, CCL11 | OPRM1 443/4885ADRB2 458/4885ADRA2A 588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.