Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL147549 | 0.97 | CASP1 (0.36) | CASP1CYP1A2LMNASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL656688 | 0.90 | CYP1A2 (0.33) | CASP1CYP1A2LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL19858970 | 0.85 | CYP1A2 (0.31) | CASP1CYP1A2 | |
| Hydrochloric Acid SCHEMBL30706492 | 0.85 | CYP1A2 (0.31) | CASP1CYP1A2 | |
| Hydrochloric Acid SCHEMBL19858971 | 0.85 | CYP1A2 (0.31) | CASP1CYP1A2 | |
| Hydrochloric Acid SCHEMBL3763676 | 0.85 | CYP1A2 (0.31) | CASP1CYP1A2 | |
| SCHEMBL33967 | 0.81 | CYP1A2 (0.32) | CASP1CYP1A2 | |
| SCHEMBL29400765 | 0.81 | CYP1A2 (0.32) | CASP1CYP1A2 | |
| SCHEMBL6943391 | 0.79 | CYP1A2 (0.31) | CASP1CYP1A2 | |
| SCHEMBL28837049 | 0.79 | CYP1A2 (0.31) | CASP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117801596-B | Photosensitive polyimide resin composition and preparation method and application thereof | 深圳先进电子材料国际创新研究院 | 2025-04-25 | — | — | CN | claimed |
| CN-118852030-A | Method for continuously synthesizing 2, 5-diamino-4, 6-dihydroxypyrimidine hydrochloride by using continuous flow reactor | 上海鲲博玖瑞医药科技发展有限公司 | 2024-10-29 | — | — | CN | claimed |
| CN-118325083-A | Photosensitive polyamic acid ester resin, photosensitive polyamic acid ester resin glue solution, preparation method and application thereof | 深圳先进电子材料国际创新研究院 | 2024-07-12 | — | — | CN | claimed |
| CN-117801596-A | Photosensitive polyimide resin composition and preparation method and application thereof | 深圳先进电子材料国际创新研究院 | 2024-04-02 | — | — | CN | claimed |
| CN-115678152-B | Thermal aging resistant asphalt modifier and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-11-03 | — | — | CN | claimed |
| CN-116925557-A | Anti-falling aging-resistant flame-retardant asphalt and mixture thereof | 中国石油化工股份有限公司 | 2023-10-24 | — | — | CN | claimed |
| CN-116925442-A | Asphalt anti-stripping aging-resistant warm mix agent and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-10-24 | — | — | CN | claimed |
| CN-116925441-A | Anti-stripping and anti-aging agent, and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-10-24 | — | — | CN | claimed |
| CN-116925490-A | Anti-falling-aging resistant agent and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-10-24 | — | — | CN | claimed |
| CN-115677267-B | Anti-falling agent, anti-falling bird repellent asphalt mixture and preparation method thereof | 中国石油化工股份有限公司 | 2023-10-10 | — | — | CN | claimed |
| CN-114479487-A | Anti-shedding agent and preparation method and application thereof | 中国石油化工股份有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-114479488-A | Anti-stripping agent and preparation method and application thereof | 中国石油化工股份有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-114477835-A | Anti-flying powder, anti-flying flame-retardant asphalt mixture and preparation method thereof | 中国石油化工股份有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-114479489-A | Anti-stripping sulfur asphalt and preparation method and application thereof | 中国石油化工股份有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-104974098-A | Synthetic method for 2,5-diamino-4,6-dihydroxypyrimidine hydrochloride | SUZHOU KAIYUAN MINSHENG SCI & TECH CORP LTD | 2015-10-14 | — | — | CN | claimed |
| CN-104496911-A | Method for synthesizing 2,5-diamino-4,6-dihydroxypyrimidine hydrochloride | SUZHOU KAIYUAN MINSHENG SCI & TECH CORP LTD | 2015-04-08 | — | — | CN | claimed |
| CN-102127022-A | Method for synthesizing 2-amino-4,6-dichloro-5-formamido pyrimidine | SUZHOU KAIYUAN MINSHENG SCI & TECH CORP LTD | 2011-07-20 | — | — | CN | claimed |
| US-20070265287-A1 | Method for Producing 2-Amino-4,6-Dichloro-5-Formamidopyrimidine | DEGISSA AG (DE) | 2007-11-15 | — | — | US | claimed |
| EP-1709010-B1 | METHOD FOR PRODUCING 2-AMINO-4,6-DICHLORO-5-FORMAMIDOPYRIMIDINE | DEGUSSA (DE) | 2007-07-25 | — | — | EP | claimed |
| US-6716981-B2 | BY REACTION OF A 2,5-DIAMINO-4,6-DIHALOPYRIMIDINE WITH FORMIC ACID | LONZA AG (CH) | 2004-04-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265287-A1 | Method for Producing 2-Amino-4,6-Dichloro-5-Formamidopyrimidine | DPYD, DHFR, DHODH | CASP1 3057/4885CYP1A2 263/4885LMNA 4106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.