Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2565232 | 0.97 | — | — | |
| SCHEMBL15624617 | 0.97 | — | — | |
| SCHEMBL514670 | 0.97 | — | — | |
| Fluoride SCHEMBL28509778 | 0.94 | — | — | |
| Sulfuric Acid SCHEMBL28013451 | 0.85 | LMNA (0.36) | — | |
| Hydrochloric Acid SCHEMBL11135283 | 0.84 | THRB (0.32) | — | |
| SCHEMBL758590 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL10439209 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL10439437 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL10439273 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115389490-A | Patterned coffee ring effect resistant hydrogel colorimetric detection test paper and preparation method and application thereof | 华南理工大学 | 2022-11-25 | — | — | CN | claimed |
| CN-115356332-A | Aerogel colorimetric diagnostic test paper with ultra-long shelf life and preparation method and application thereof | 华南理工大学 | 2022-11-18 | — | — | CN | claimed |
| CN-211049582-U | Cryogenic conduit and cryogenic control system | 首都医科大学宣武医院 | 2020-07-21 | — | — | CN | claimed |
| CN-115389490-A | Patterned coffee ring effect resistant hydrogel colorimetric detection test paper and preparation method and application thereof | 华南理工大学 | 2022-11-25 | — | — | CN | disclosed |
| CN-115356332-A | Aerogel colorimetric diagnostic test paper with ultra-long shelf life and preparation method and application thereof | 华南理工大学 | 2022-11-18 | — | — | CN | disclosed |
| CN-211049582-U | Cryogenic conduit and cryogenic control system | 首都医科大学宣武医院 | 2020-07-21 | — | — | CN | disclosed |
| CN-108017550-A | A kind of 3- amino -1,2-PD production new technique | 内蒙古圣氏化学股份有限公司 | 2018-05-11 | — | — | CN | disclosed |
| CN-107531029-A | Active energy ray-curable resin composition, antifogging and antifouling laminate, article and method for producing same, and antifouling method | 迪睿合株式会社 | 2018-01-02 | — | — | CN | disclosed |
| CN-107405861-A | Antifog antifouling layered product and its manufacture method, article and its manufacture method and anti-fouling method | 迪睿合株式会社 | 2017-11-28 | — | — | CN | disclosed |
| EP-1385834-A1 | BICYCLO[3,1,0]HEXANE CONTAINING OXAZOLIDINONE ANTIBIOTIC AND DERIVATIVES THEREOF | Merck & Co., Inc. (US) | 2004-02-04 | — | — | EP | disclosed |
| WO-2003027083-A1 | BICYCLO[3,1,0]HEXANE CONTAINING OXAZOLIDINONE ANTIBIOTIC AND DERIVATIVES THEREOF | MERCK & CO., INC. (US) | 2003-04-03 | — | — | WO | disclosed |
| CN-1045109-C | Concentrated fabric softener compositions containing biodegradable fabric softeners | PROCTER & GAMBLE (US) | 1999-09-15 | — | — | CN | disclosed |
| CN-1082101-A | The concentrated fabric softener compositions that contains biodegradable fabric softener | PROCTER & GAMBLE (US) | 1994-02-16 | — | — | CN | disclosed |
| US-5234934-A | Derivatives of a 1-(2-hydroxy-3-N-hetpropoxyimino)-2-phenyl methylene)cycloalkane; antiarrhymia,-secretory and -inflammatory agents; tranquilizers; local anaesthetics | EGIS GYOGYSZERGYAR (HU) | 1993-08-10 | — | — | US | disclosed |
| EP-0377532-B1 | THIOFORMAMIDE DERIVATIVES | MAY AND BAKER LIMITED (GB) | 1992-07-29 | — | — | EP | disclosed |
| US-5130487-A | Cardiovascular disorders, tranquilizers for central nervous systems or for digestive system problems | EGIS GYOGYSZERGYAR (HU) | 1992-07-14 | — | — | US | disclosed |
| US-5104883-A | Cardiovascular, respiratory, gastrointestirol, urogenital disorders; baldness; premature labor | MAY & BAKER LIMITED (GB) | 1992-04-14 | — | — | US | disclosed |
| EP-0377532-A1 | Thioformamide derivatives | MAY AND BAKER LIMITED (GB) | 1990-07-11 | — | — | EP | disclosed |
| US-4404384-A | HYPOTENSIVE, ANTISPASMODIC, CHOLERETIC AGENTS; ANTICONUULSANTS; ANTIPYRETICS; ANTHELMINTICS; FUNGICIDWS | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-09-13 | — | — | US | disclosed |