Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27260142 | 0.98 | — | — | |
| Bromide SCHEMBL27438230 | 0.96 | — | — | |
| SCHEMBL27260017 | 0.96 | — | — | |
| Benzene SCHEMBL28489637 | 0.82 | — | — | |
| Toluene SCHEMBL7669666 | 0.82 | LMNA (0.44) | — | |
| Biphenyl SCHEMBL819335 | 0.81 | ALDH1A1 (0.39) | CYP3A4MAPT | |
| Hydrochloric Acid SCHEMBL647872 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL124212 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL4251544 | 0.79 | — | — | |
| Toluene SCHEMBL28481276 | 0.79 | LMNA (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101939343-B | Method for controlling bimodal catalyst activity during polymerization | UNIVATION TECH LLC | 2013-10-02 | — | — | CN | disclosed |
| CN-103328414-A | Process for producing alpha-olefin oligomer | IDEMITSU KOSAN CO | 2013-09-25 | — | — | CN | disclosed |
| CN-102216414-A | Base oil for oil drilling fluid and oil drilling fluid composition | IDEMITSU KOSAN CO | 2011-10-12 | — | — | CN | disclosed |
| CN-101939343-A | Method for controlling bimodal catalyst activity during polymerization | UNIVATION TECH LLC | 2011-01-05 | — | — | CN | disclosed |
| CN-101070360-A | Polyethylene resins with bimodal molecular weight distribution | UNIVATION TECH LLC (US) | 2007-11-14 | — | — | CN | disclosed |
| CN-100343291-C | Polyethylene resins with bimodal molecular weight distribution and use | EXXONMOBIL CHEM PATENTS INC (US) | 2007-10-17 | — | — | CN | disclosed |
| CN-1283669-C | Control of solution catalyst droplets | UNION CARBIDE CHEM PLASTIC (US) | 2006-11-08 | — | — | CN | disclosed |
| CN-1269853-C | Catalyst for producing alpha-olefin and method for producing alpha-olefin | IDEMITSU PETROCHEMICAL CO (JP) | 2006-08-16 | — | — | CN | disclosed |
| CN-1257195-C | Bimetallic catalyst for producing polyethylene resins with bimodal molecular weight distribution, its preparation and use | EXXONMOBIL CHEM PATENTS INC (US) | 2006-05-24 | — | — | CN | disclosed |
| CN-1693315-A | Polyethylene resins with bimodal molecular weight distribution and use | EXXONMOBIL CHEM PATENTS INC (US) | 2005-11-09 | — | — | CN | disclosed |
| CN-1277211-A | Molecular weight of polymer produced by single-point catalyst control and method of molecular weight distrubution | UNION CARBIDE CHEM PLASTIC (US) | 2000-12-20 | — | — | CN | disclosed |
| CN-1275134-A | Catalyst for olefin polymer production, process for producing the same, and process for producing olefin polymer | IDEMITSU PETROCHEMICAL CO (JP) | 2000-11-29 | — | — | CN | disclosed |
| CN-1054859-C | Gas phase polymerization reactions utilizing solubl unsupported catalysts | UNION GARBIDE CHEMICALS & PLAS (US) | 2000-07-26 | — | — | CN | disclosed |
| CN-1239482-A | Catalysts for polymerization of olefins, process for prodn. of olefin polymers, and processes for prodn. of styrene polymers | IDEMITSU PETROCHEMICAL CO (JP) | 1999-12-22 | — | — | CN | disclosed |
| CN-1178222-A | Process for controlling static in polymerizations utilizing metallocene catalysts | UNION CARBIDE CHEM PLASTIC (US) | 1998-04-08 | — | — | CN | disclosed |
| CN-1155293-A | Oil-soluble dispersant additives based on 1-butene-alpha-olefin copolymers | EXXON CHEMICAL PATENTS INC (US) | 1997-07-23 | — | — | CN | disclosed |
| CN-1123795-A | Compositions useful for olefin polymerization and processes therefor and therewith | PHILLIPS PETROLEUM CO (US) | 1996-06-05 | — | — | CN | disclosed |
| CN-1088939-A | Use the solubility unsupported catalyst to carry out gas phase polymerization | UNION CARBIDE CHEM PLASTIC (US) | 1994-07-06 | — | — | CN | disclosed |
| CN-1020193-C | Benzene-insoluble organoaluminum oxy-compounds and process for preparing same | MITSUIPETROCHEMICAL IND LTD (JP) | 1993-03-31 | — | — | CN | disclosed |
| CN-1041597-A | Benzene-insoluble Organoaluminoxy based compound and preparation method thereof | MITSUI PETROCHEMICAL IND (JP) | 1990-04-25 | — | — | CN | disclosed |