Mercaptopurine Anhydrous

Mercaptopurine Anhydrous

SCHEMBL734087

O.Sc1ncnc2[nH]cnc12

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

PPAT

The experimentally established mechanism targets of Mercaptopurine Anhydrous. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PI4KA P42356 2/20 0.32
PI4K2B Q8TCG2 2/20 0.32
PI4K2A Q9BTU6 2/20 0.32
PI4KB Q9UBF8 2/20 0.32
LMNA P02545 1/20 0.32
DRD3 P35462 1/20 0.32
XDH P47989 1/20 0.32
LRRK2 Q5S007 1/20 0.32
CSNK2A2 P19784 2/20 0.30
CSNK2A1 P68400 2/20 0.30
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30
HPGD P15428 1/20 0.30
PTGS1 P23219 1/20 0.30
HBB P68871 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
MEN1 O00255 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mercaptopurine Anhydrous SCHEMBL8843 0.98 PI4KA (0.33) PI4KAPI4K2BPI4K2API4KBLMNA
Mercaptopurine Anhydrous SCHEMBL5144252 0.96 PI4KA (0.32) PI4KAPI4K2BPI4K2API4KBLMNA
Mercaptopurine Anhydrous SCHEMBL7199288 0.82
Mercaptopurine Anhydrous SCHEMBL12476114 0.81 ALDH1A1 (0.62) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL2895675 0.76 PI4KA (0.47) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL2772644 0.76 PI4KA (0.47) PI4KAPI4K2BPI4K2API4KBLMNA
Mercaptopurine Anhydrous SCHEMBL18317326 0.75 LMNA (0.51) LMNAALDH1A1HBBSMN1; SMN2
Adenine SCHEMBL2428538 0.74 PI4KA (0.48) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL2428541 0.74 PI4KA (0.48) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL8110 0.73 PI4KA (0.48) PI4KAPI4K2BPI4K2API4KBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 237 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240115705-A1 Regulation of Butyrophilin subfamily 3 member A1 (BTN3A1, CD277) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2024-04-11 US claimed
CN-117295505-A Modulation of the milk philin subfamily 3 member A1 (BTN 3A1, CD 277) 加利福尼亚大学董事会 2023-12-26 CN claimed
EP-4288074-A1 REGULATION OF BUTVROPHILIN SUBFAMILY 3 MEMBER A1 (BTN3A1, CD277) The Regents of The University of California Santa Cruz (US) 2023-12-13 EP claimed
WO-2022170344-A1 REGULATION OF BUTVROPHILIN SUBFAMILY 3 MEMBER A1 (BTN3A1, CD277) MARSON ALEXANDER (US) 2022-08-11 WO claimed
US-20140294972-A1 Oral Suspension NOVA BIO-PHARMA TECHNOLOGIES LIMITED (GB) 2014-10-02 US claimed
US-8765712-B2 Agent for preventing and treating pityriasis versicolor JUSTUS-LIEBIG-UNIVERSITAET GIESSEN (DE) 2014-07-01 US claimed
WO-2013034931-A1 ORAL SUSPENSION NOVA BIO-PHARMA TECHNOLOGIES LIMITED (GB) 2013-03-14 WO claimed
US-20120129800-A1 Agent For Preventing And Treating Pityriasis Versicolor JUSTUS-LIEBIG-UNIVERSITAT GIESSEN (DE) 2012-05-24 US claimed
EP-2175860-A2 NR4A AGONISTS (6-MERCAPTOPURINE) FOR INHIBITION OF NON-OCULAR SCARRING Renovo Limited (GB) 2010-04-21 EP claimed
WO-2009016379-A2 NR4A AGONISTS ( 6-MERCAPTOPURINE) FOR INHIBITION OF NON-OCULAR SCARRING RENOVO LIMITED (GB) 2009-02-05 WO claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
US-5854231-A Pharmaceutical composition for inhibiting the growth of cancers THE PROCTER & GAMBLE COMPANY (US) 1998-12-29 US claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
US-5043237-A Inhibitor-containing photohardenable electrostatic master compositions having improved resolution E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-08-27 US claimed
EP-0436948-A2 Inhibitor-containing photohardenable compositions having improved resolution E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-07-17 EP claimed
CN-120004760-A Ultrasonic activated azido precursor, prodrug and application 中国科学院长春应用化学研究所 2025-05-16 CN disclosed
US-20250144067-A1 PERSONALIZED STARVATION THERAPY FOR CANCER FAETH THERAPEUTICS, INC. 2025-05-08 US disclosed
US-20240377736-A1 PHOTOSENSITIVE COMPOSITION ARKEMA FRANCE (FR) 2024-11-14 US disclosed
WO-2024189607-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT DIDENKO KIRILL (MX) 2024-09-19 WO disclosed
EP-3604310-B1 CDC-7-INHIBITOR COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS CONSEJO SUPERIOR INVESTIGACION (ES) 2024-09-11 EP disclosed
EP-4401983-A1 PHOTOSENSITIVE COMPOSITION ARKEMA FRANCE (FR) 2024-07-24 EP disclosed
US-11986479-B2 Combination drug products for treating patients suffering from one or more medical conditions caused by coronavirus infection, including by SARS-CoV-2, its alpha, beta, delta, or omicron variants and sub variants PharSoln, Inc. (US) 2024-05-21 US disclosed
CN-118019645-A Photosensitive composition 阿科玛法国公司 2024-05-10 CN disclosed
US-11959065-B2 Bacillus megaterium bioactive compositions and metabolites PRO FARM GROUP, INC. (US) 2024-04-16 US disclosed
US-20240115705-A1 Regulation of Butyrophilin subfamily 3 member A1 (BTN3A1, CD277) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2024-04-11 US disclosed
US-20240024329-A1 COMBINATION DRUG PRODUCTS FOR TREATING PATIENTS SUFFERING FROM ONE OR MORE MEDICAL CONDITIONS CAUSED BY CORONAVIRUS INFECTION, INCLUDING BY SARS-CoV-2, ITS ALPHA, BETA, DELTA, OR OMICRON VARIANTS AND SUB VARIANTS PharSoln, Inc. (US) 2024-01-25 US disclosed
CN-117295505-A Modulation of the milk philin subfamily 3 member A1 (BTN 3A1, CD 277) 加利福尼亚大学董事会 2023-12-26 CN disclosed
EP-4288074-A1 REGULATION OF BUTVROPHILIN SUBFAMILY 3 MEMBER A1 (BTN3A1, CD277) The Regents of The University of California Santa Cruz (US) 2023-12-13 EP disclosed
WO-2023041579-A1 PHOTOSENSITIVE COMPOSITION ARKEMA FRANCE (FR) 2023-03-23 WO disclosed
EP-4151410-A1 PHOTOSENSITIVE COMPOSITION ARKEMA FRANCE (FR) 2023-03-22 EP disclosed
US-20220315885-A1 BACILLUS MEGATERIUM BIOACTIVE COMPOSITIONS AND METABOLITES MARRONE BIO INNOVATIONS, INC. (US) 2022-10-06 US disclosed
US-11446304-B2 CDC-7-inhibitor compounds and use thereof for the treatment of neurological conditions CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) 2022-09-20 US disclosed
WO-2022170344-A1 REGULATION OF BUTVROPHILIN SUBFAMILY 3 MEMBER A1 (BTN3A1, CD277) MARSON ALEXANDER (US) 2022-08-11 WO disclosed
US-11384332-B2 Bacillus megaterium bioactive compositions and metabolites MARRONE BIO INNOVATIONS, INC. (US) 2022-07-12 US disclosed
US-11219895-B2 Blood analysis cartridge KING ABDULAZIZ UNIVERSITY (SA) 2022-01-11 US disclosed
US-20210346388-A1 CDC7-Inhibiting Purine Derivatives and their use for the Treatment of Neurological Conditions CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC) (ES) 2021-11-11 US disclosed
US-20210308674-A1 BLOOD ANALYSIS CARTRIDGE KING ABDULAZIZ UNIVERSITY (SA) 2021-10-07 US disclosed
EP-3854401-A1 CDC7-INHIBITING PURINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS Consejo Superior de Investigaciones Científicas (CSIC) (ES) 2021-07-28 EP disclosed
EP-3155395-B1 METHODS AND COMPOSITIONS FOR STABILIZATION OF NUCLEIC ACIDS IN A BLOOD SAMPLE AT AMBIENT TEMPERATURES BIOMATRICA INC (US) 2021-06-02 EP disclosed
US-20210060016-A1 ANTICANCER AGENT JAPANESE FOUNDATION FOR CANCER RESEARCH (JP) 2021-03-04 US disclosed
US-20210001333-A1 MICROFLUIDIC DEVICE FOR MEASURING THE ENZYMATIC ACTIVITY OF THIOPURIN S-METHYLTRANSFERASE KING ABDULAZIZ UNIVERSITY (SA) 2021-01-07 US disclosed
EP-3733206-A1 ANTICANCER AGENT Japanese Foundation For Cancer Research (JP) 2020-11-04 EP disclosed
US-20200267991-A1 BACILLUS MEGATERIUM BIOACTIVE COMPOSITIONS AND METABOLITES MARRONE BIO INNOVATIONS, INC. (US) 2020-08-27 US disclosed
US-10695349-B2 Inhibitors of human phosphatidylinositol 3-kinase delta ICOS CORPORATION (US) 2020-06-30 US disclosed
US-10645936-B2 Bacillus megaterium bioactive compositions and metabolites MARRONE BIO INNOVATIONS, INC. (US) 2020-05-12 US disclosed
US-10602743-B2 Method of inducing drought/salt tolerance using Bacillus megaterium MARRONE BIO INNOVATIONS, INC. (US) 2020-03-31 US disclosed
US-20200093828-A1 CDC-7-INHIBITOR COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC) (ES) 2020-03-26 US disclosed
WO-2020058558-A1 CDC7-INHIBITING PURINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) 2020-03-26 WO disclosed
US-20200061062-A1 INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA ICOS CORPORATION 2020-02-27 US disclosed
US-20200048265-A1 HETEROCYCLIC COMPOUNDS AND THEIR USES AMGEN INC. (US) 2020-02-13 US disclosed
EP-3604310-A1 CDC-7-INHIBITOR COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS Consejo Superior de Investigaciones Cientificas (CSIC) (ES) 2020-02-05 EP disclosed
EP-3083617-B1 ISOCHROMENE DERIVATIVES AS PHOSPHOINOSITIDE 3-KINASES INHIBITORS CHIESI FARM SPA (IT) 2019-09-11 EP disclosed
US-10398695-B2 Inhibitors of human phosphatidylinositol 3-kinase delta ICOS CORPORATION (US) 2019-09-03 US disclosed
US-20180360832-A1 INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA ICOS CORPORATION 2018-12-20 US disclosed
US-10010550-B2 Inhibitors of human phosphatidylinositol 3-kinase delta ICOS CORPORATION (US) 2018-07-03 US disclosed
US-20180105532-A1 HETEROCYCLIC COMPOUNDS AND THEIR USES AMGEN INC. (US) 2018-04-19 US disclosed
US-20180042241-A1 BACILLUS MEGATERIUM BIOACTIVE COMPOSITIONS AND METABOLITES PRO FARM GROUP, INC. 2018-02-15 US disclosed
US-9873701-B2 Heterocyclic compounds and their uses AMGEN INC. (US) 2018-01-23 US disclosed
US-20170340633-A1 INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA ICOS CORPORATION 2017-11-30 US disclosed
US-9801386-B2 Bacillus megaterium bioactive compositions and metabolites MARRONE BIO INNOVATIONS, INC. (US) 2017-10-31 US disclosed
US-20170198335-A1 Stabilization of Non-Denatured Polypeptides, Nucleic Acids, and Exosomes in a Blood Sample at Ambient Temperatures BIOMATRICA, INC. (US) 2017-07-13 US disclosed
US-20170049772-A1 INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA ICOS CORPORATION 2017-02-23 US disclosed
US-9487772-B2 Inhibitors of human phosphatidylinositol 3-kinase delta ICOS CORPORATION (US) 2016-11-08 US disclosed
EP-3083617-A1 ISOCHROMENE DERIVATIVES AS PHOSPHOINOSITIDE 3-KINASES INHIBITORS Chiesi Farmaceutici S.p.A. (IT) 2016-10-26 EP disclosed
WO-2014028520-A9 BACILLUS MEGATERIUM BIOACTIVE COMPOSITIONS AND METABOLITES MARRONE BIO INNOVATIONS, INC. (US) 2016-08-04 WO disclosed
CN-105829308-A Isochromene derivatives as phosphoinositide 3-kinase inhibitors 奇斯药制品公司 2016-08-03 CN disclosed
EP-3045458-A1 HETEROCYCLIC COMPOUNDS AND THEIR USES Amgen, Inc (US) 2016-07-20 EP disclosed
EP-3029041-A1 INHIBITORS OF HUMAN PHOSPHATIDYL-INOSITOL 3-KINASE DELTA ICOS Corporation (US) 2016-06-08 EP disclosed
US-9321776-B2 Isochromene derivatives as phoshoinositide 3-kinases inhibitors CHIESI FARMACEUTICI S.P.A. (IT) 2016-04-26 US disclosed
EP-2223922-B1 Inhibitors of human phosphatidyl-inositol 3-kinase delta ICOS CORP (US) 2016-03-02 EP disclosed
EP-2137186-B1 HETEROCYCLIC COMPOUNDS AND THEIR USES AMGEN INC (US) 2016-01-27 EP disclosed
US-20150305346-A1 BACILLUS MEGATERIUM BIOACTIVE COMPOSITIONS AND METABOLITES MARRONE BIO INNOVATIONS, INC. 2015-10-29 US disclosed
US-9084428-B2 Bacillus megaterium bioactive compositions and metabolites MARRONE BIO INNOVATIONS, INC. (US) 2015-07-21 US disclosed
WO-2015091685-A1 ISOCHROMENE DERIVATIVES AS PHOSPHOINOSITIDE 3-KINASES INHIBITORS CHIESI FARMACEUTICI S.P.A. (IT) 2015-06-25 WO disclosed
EP-2885399-A1 BACILLUS MEGATERIUM BIOACTIVE COMPOSITIONS AND METABOLITES Marrone Bio Innovations, Inc. (US) 2015-06-24 EP disclosed
US-20150166549-A1 ISOCHROMENE DERIVATIVES AS PHOSHOINOSITIDE 3-KINASES INHIBITORS CHIESI FARMACEUTICI S.P.A. (IT) 2015-06-18 US disclosed
US-20150118311-A1 Highly Penetrative Nanocarriers for Treatment of CNS Disease Yale Universit (US) 2015-04-30 US disclosed
US-20150045361-A1 HETEROCYCLIC COMPOUNDS AND THEIR USES AMGEN INC (US) 2015-02-12 US disclosed
US-8901135-B2 Heterocyclic compounds and their uses AMGEN INC. (US) 2014-12-02 US disclosed
US-20140294972-A1 Oral Suspension NOVA BIO-PHARMA TECHNOLOGIES LIMITED (GB) 2014-10-02 US disclosed
US-8765712-B2 Agent for preventing and treating pityriasis versicolor JUSTUS-LIEBIG-UNIVERSITAET GIESSEN (DE) 2014-07-01 US disclosed
US-20140154772-A1 INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA ICOS CORPORATION (US) 2014-06-05 US disclosed
US-20140051571-A1 BACILLUS MEGATERIUM BIOACTIVE COMPOSITIONS AND METABOLITES PRO FARM GROUP, INC. 2014-02-20 US disclosed
WO-2014028520-A1 BACILLUS MEGATERIUM BIOACTIVE COMPOSITIONS AND METABOLITES MARRONE BIO INNOVATIONS, INC. (US) 2014-02-20 WO disclosed
US-8653077-B2 Inhibitors of human phosphatidylinositol 3-kinase delta ICOS CORPORATION (US) 2014-02-18 US disclosed
US-8637533-B2 Inhibitors of human phosphatidylinositol 3-kinase delta ICOS CORPORATION (US) 2014-01-28 US disclosed
US-8623881-B2 Inhibitors of human phosphatidylinositol 3-kinase delta ICOS CORPORATION (US) 2014-01-07 US disclosed
US-8586739-B2 Heterocyclic compounds and their uses AMGEN INC. (US) 2013-11-19 US disclosed
EP-1834977-B1 OPTICAL REFRACTIVE INDEX-MODIFYING POLYMER COMPOSITION, HOLOGRAPHIC RECORDING MATERIAL AND METHOD OF CONTROLLING REFRACTIVE INDEX NITTO DENKO CORP (JP) 2013-08-21 EP disclosed
US-8492389-B2 Inhibitors of human phosphatidylinositol 3-kinase delta ICOS CORPORATION (US) 2013-07-23 US disclosed
WO-2013034931-A1 ORAL SUSPENSION NOVA BIO-PHARMA TECHNOLOGIES LIMITED (GB) 2013-03-14 WO disclosed
WO-2012146667-A1 IMIDAZOPYRIDINE DERIVATIVES AS PI3K INHIBITORS ALMIRALL, S.A. (ES) 2012-11-01 WO disclosed
EP-2518071-A1 Imidazopyridine derivatives as PI3K inhibitors Almirall, S.A. (ES) 2012-10-31 EP disclosed
US-20120220586-A1 HETEROCYCLIC COMPOUNDS AND THEIR USES AMGEN INC. (US) 2012-08-30 US disclosed
US-20120220585-A1 HETEROCYCLIC COMPOUNDS AND THEIR USES AMGEN INC. (US) 2012-08-30 US disclosed
EP-2491923-A2 Combinations of therapeutic agents for treating cancer Novartis AG (CH) 2012-08-29 EP disclosed
US-20120172591-A1 INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA ICOS CORPORATION (US) 2012-07-05 US disclosed
US-8193199-B2 Heterocyclic compounds and their uses AMGEN INC. (US) 2012-06-05 US disclosed
US-20120135994-A1 INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA ICOS CORPORATION (US) 2012-05-31 US disclosed
US-20120129800-A1 Agent For Preventing And Treating Pityriasis Versicolor JUSTUS-LIEBIG-UNIVERSITAT GIESSEN (DE) 2012-05-24 US disclosed
EP-2441768-A1 Thienopyrimidinones for treatment of inflammatory disorders and cancers Eli Lilly & Co. (US) 2012-04-18 EP disclosed
US-8138195-B2 Inhibitors of human phosphatidylinositol 3-kinase delta ICOS CORPORATION (US) 2012-03-20 US disclosed
EP-1669378-B1 LIGHT REFRACTIVE INDEX MODULATION POLYMER COMPOSITION AND METHOD OF CONTROLLING REFRACTIVE INDEX NITTO DENKO CORP (JP) 2012-01-18 EP disclosed
EP-2359818-A1 Combination of LBH589 with HSP 90 inhibitors for treating cancer Novartis AG (CH) 2011-08-24 EP disclosed
EP-1278748-B1 INHIBITORS OF HUMAN PHOSPHATIDYL-INOSITOL 3-KINASE DELTA ICOS CORP (US) 2011-03-23 EP disclosed
US-20110021541-A1 INHIBITORS OF HUMAN PHOSPHATIDYL-INOSITOL 3-KINASE DELTA ICOS CORPORATION 2011-01-27 US disclosed
EP-2223922-A2 Inhibitors of human phosphatidyl-inositol 3-kinase delta ICOS Corporation (US) 2010-09-01 EP disclosed
US-20100216820-A1 THIENOPYRIMIDIONES FOR TREATMENT OF INFLAMMATORY DISORDERS AND CANCERS ICOS CORPORATION 2010-08-26 US disclosed
EP-2220089-A2 INHIBITORS OF HUMAN PHOSPHATIDYL-INOSITOL 3-KINASE DELTA ICOS CORPORATION (US) 2010-08-25 EP disclosed
US-7781124-B2 Hologram recording material NITTO DENKO CORPORATION (JP) 2010-08-24 US disclosed
US-20100204248-A1 MEDICAMENTS AND METHODS FOR INHIBITION OF NON-OCULAR SCARRING RENOVO LIMITED 2010-08-12 US disclosed
US-7759361-B2 treating a cancer, autoimmune diseases and cardiovscular disorders comprising administering drugs such as Isobutyric acid 2-isobutyryloxymethyl-3-oxo-1-aza-bicyclo[2.2.2]oct-ylmethyl ester; antiproliferative agents APREA AB (SE) 2010-07-20 US disclosed
US-20100168139-A1 INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA ICOS CORPORATION 2010-07-01 US disclosed
US-20100152211-A1 INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA ICOS CORPORATION 2010-06-17 US disclosed
US-7727679-B2 Optical refractive index-modifying polymer composition, hologram recording material and method of controlling refractive index NITTO DENKO CORPORATION (JP) 2010-06-01 US disclosed
EP-2175860-A2 NR4A AGONISTS (6-MERCAPTOPURINE) FOR INHIBITION OF NON-OCULAR SCARRING Renovo Limited (GB) 2010-04-21 EP disclosed
CN-101626758-A Combination of LBH589 and other therapeutic agents for the treatment of cancer NOVARTIS AG 2010-01-13 CN disclosed
EP-2137186-A1 HETEROCYCLIC COMPOUNDS AND THEIR USES Amgen Inc. (US) 2009-12-30 EP disclosed
EP-1450822-B1 Polyalkylene oxide conjugates of thiol-containing drugs ENZON INC (US) 2009-12-23 EP disclosed
EP-2097422-A1 THIENOPYRIMIDINONES FOR TREATMENT OF INFLAMMATORY DISORDERS AND CANCERS Eli Lilly & Co. (US) 2009-09-09 EP disclosed
US-7566745-B2 Photochemically refractive-index-changing polymer, photochemically refractive-index-changing polymer composition, and method of refractive index regulation NITTO DENKO CORPORATION (JP) 2009-07-28 US disclosed
US-20090137581-A1 Heterocyclic compounds and their uses AMGEN INC. 2009-05-28 US disclosed
WO-2009064802-A2 INHIBITORS OF HUMAN PHOSPHATIDYL-INOSITOL 3-KINASE DELTA ELI LILLY & CO. (US) 2009-05-22 WO disclosed
WO-2009016379-A2 NR4A AGONISTS ( 6-MERCAPTOPURINE) FOR INHIBITION OF NON-OCULAR SCARRING RENOVO LIMITED (GB) 2009-02-05 WO disclosed
CN-101356189-A Hepatocyte growth factor intron fusion proteins RECEPTOR BIOLOGIX INC (US) 2009-01-28 CN disclosed
US-20080305404-A1 Which can vary refractive index upon irradiation with visible light laser and exhibits an excellent transparency after the modulation without requiring any conventional complicated procedure; syndiotactic acrylic ester polymer with side chain vinyl group, and specific photopolymerization initiator NITTO DENKO CORPORATION (JP) 2008-12-11 US disclosed
WO-2008118468-A1 HETEROCYCLIC COMPOUNDS AND THEIR USES AMGEN INC. (US) 2008-10-02 WO disclosed
US-20080226601-A1 Herpes Virus-Based Compositions and Methods of Use in the Prenatal and Perinatal Periods UNIVERSITY OF ROCHESTER (US) 2008-09-18 US disclosed
EP-1954714-A2 HEPATOCYTE GROWTH FACTOR INTRON FUSION PROTEINS Receptor Biologix, Inc. (US) 2008-08-13 EP disclosed
EP-1939203-A2 Inhibitors of human phosphatidyl-inositol 3-kinase delta isoform ICOS Corporation (US) 2008-07-02 EP disclosed
EP-1492803-B1 NEW ANALOGS OF NITROBENZYLTHIOINOSINE GRUENENTHAL GMBH (DE) 2008-06-11 EP disclosed
WO-2008064018-A1 THIENOPYRIMIDINONES FOR TREATMENT OF INFLAMMATORY DISORDERS AND CANCERS ELI LILLY & CO. (US) 2008-05-29 WO disclosed
US-20080103110-A1 Compounds DRUG DISCOVERY LABORATORY AS (NO) 2008-05-01 US disclosed
US-7358235-B2 Analogs of nitrobenzylthioinosine GRUENENTHAL GMBH (DE) 2008-04-15 US disclosed
EP-1903873-A2 HERPES VIRUS-BASED COMPOSITIONS AND METHODS OF USE IN THE PRENATAL AND PERINATAL PERIODS THE UNIVERSITY OF ROCHESTER (US) 2008-04-02 EP disclosed
EP-1873593-A1 HOLOGRAM RECORDING MATERIAL NITTO DENKO CORPORATION (JP) 2008-01-02 EP disclosed
US-20070259889-A1 Protein Binding Compounds DRUG DISCOVERY LABORATORY AS (NO) 2007-11-08 US disclosed
EP-1834977-A1 OPTICAL REFRACTIVE INDEX-MODIFYING POLYMER COMPOSITION, HOLOGRAM RECORDING MATERIAL AND METHOD OF CONTROLLING REFRACTIVE INDEX NITTO DENKO CORPORATION (JP) 2007-09-19 EP disclosed
US-20070161081-A1 Hepatocyte growth factor intron fusion proteins RECEPTOR BIOLOGIX, INC. (US) 2007-07-12 US disclosed
EP-1804838-A2 DRUG CONJUGATES OF LONG CHAIN FATTY ACID OR ESTER MOIETIES AS PROTEIN BINDING PRODRUGS Drug Discovery Laboratory AS (NO) 2007-07-11 EP disclosed
US-20070142370-A1 Azabicyclooctan-3-one derivatives and use thereof APREA AB (SE) 2007-06-21 US disclosed
US-20070128523-A1 Optical refractive index-modifying polymer composition, hologram recording material and method of controlling refractive index NITTO DENKO CORPORATION (JP) 2007-06-07 US disclosed
WO-2007058776-A2 HEPATOCYTE GROWTH FACTOR INTRON FUSION PROTEINS RECEPTOR BIOLOGIX, INC. (US) 2007-05-24 WO disclosed
US-20070099871-A1 Bioreductively-activated prodrugs ANGIOGENE PHARMACEUTICALS LIMITED (GB) 2007-05-03 US disclosed
US-20070066705-A1 Photochemically refractive-index-changing polymer, photochemically refractive-index-changing polymer composition, and method of refractive index regulation NITTO DENKO CORPORATION (JP) 2007-03-22 US disclosed
WO-2006135602-A2 HERPES VIRUS-BASED COMPOSITIONS AND METHODS OF USE IN THE PRENATAL AND PERINATAL PERIODS UNIVERSITY OF ROCHESTER (US) 2006-12-21 WO disclosed
EP-1727817-A1 AZABICYCLOOCTAN-3-ONE DERIVATIVES AND USE THEREOF APREA AB (SE) 2006-12-06 EP disclosed
EP-1669378-A1 LIGHT REFRACTIVE INDEX MODULATION POLYMER, LIGHT REFRACTIVE INDEX MODULATION POLYMER COMPOSITION AND METHOD OF CONTROLLING REFRACTIVE INDEX NITTO DENKO CORPORATION (JP) 2006-06-14 EP disclosed
EP-1663181-A2 PROTEIN BINDING COMPOUNDS Drug Discovery Laboratory AS (NO) 2006-06-07 EP disclosed
US-7033583-B2 Polymeric thiol-linked prodrugs ENZON PHARMACEUTICALS, INC. (US) 2006-04-25 US disclosed
EP-1450822-A4 POLYMERIC THIOL-LINKED PRODRUGS ENZON INC (US) 2006-04-05 EP disclosed
WO-2006030217-A2 DRUG CONJUGATES OF LONG CHAIN FATTY ACID OR ESTER MOIETIES AS PROTEIN BINDING PRODRUGS DRUG DISCOVERY LABORATORY AS (NO) 2006-03-23 WO disclosed
EP-1613612-A2 BIOREDUCTIVELY-ACTIVATED PRODRUGS Angiogene Pharmaceuticals Limited (GB) 2006-01-11 EP disclosed
US-20050261317-A1 Inhibitors of human phosphatidylinositol 3-kinase delta ICOS CORPORATION (US) 2005-11-24 US disclosed
WO-2005090341-A1 AZABICYCLOOCTAN-3-ONE DERIVATIVES AND USE THEREOF APREA AB (SE) 2005-09-29 WO disclosed
US-6949535-B2 for example, 2-(6-aminopurin-9-ylmethyl)-3-(2-chlorophenyl)-6,7-dimethoxy-3H-quinazolin-4-one ICOS CORPORATION (US) 2005-09-27 US disclosed
US-20050096293-A1 Analogs of nitrobenzylthioinosine GRUENENTHAL GMBH (DE) 2005-05-05 US disclosed
WO-2005025552-A2 PROTEIN BINDING COMPOUNDS DRUG DISCOVERY LABORATORY AS (NO) 2005-03-24 WO disclosed
US-6846525-B2 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORPORATION (US) 2005-01-25 US disclosed
EP-1492803-A1 NEW ANALOGS OF NITROBENZYLTHIOINOSINE Grünenthal GmbH (DE) 2005-01-05 EP disclosed
US-20040266780-A1 for example, 2-(6-aminopurin-9-ylmethyl)-3-(2-chlorophenyl)-6,7-dimethoxy-3H-quinazolin-4-one ICOS CORPORATION 2004-12-30 US disclosed
US-20040202825-A1 RECORDING SHEETS CONTAINING PURINE, PYRIMIDINE, BENZIMIDAZOLE, IMIDAZOLIDINE, URAZOLE, PYRAZOLE, TRIAZOLE, BENZOTRIAZOLE, TETRAZOLE, AND PYRAZINE COMPOUNDS XEROX CORPORATION 2004-10-14 US disclosed
WO-2004085421-A2 BIOREDUCTIVELY-ACTIVATED PRODRUGS ANGIOGENE PHARMACEUTICALS LIMITED (GB) 2004-10-07 WO disclosed
US-6800620-B2 CONTACTING LEUKOCYTES, OSTEOCLASTS WITH AN ENZYME INHIBITORS, A 9H-PURIN-3H-QUINAZOLIN-4-ONE DERIVATIVES, TREATING BONE-RESORPTION DISORDER, ANTIPROLIFERATIVE AGENTS TREATING LEUKEMIA CELLS ICOS 2004-10-05 US disclosed
EP-1450822-A2 POLYMERIC THIOL-LINKED PRODRUGS ENZON, INC. (US) 2004-09-01 EP disclosed
EP-1438052-A1 INHIBITORS OF HUMAN PHOSPHATIDYL−INOSITOL 3−KINASE DELTA ICOS CORPORATION (US) 2004-07-21 EP disclosed
US-6667300-B2 Purinyl substituted quinazoline-4-one derivatives ICOS CORPORATION 2003-12-23 US disclosed
US-20030195211-A1 Inhibitors of human phosphatidylinositol 3-kinase delta ICOS CORPORATION 2003-10-16 US disclosed
WO-2003084975-A1 NEW ANALOGS OF NITROBENZYLTHIOINOSINE Grünenthal GmbH (DE) 2003-10-16 WO disclosed
EP-1352910-A1 New analogs of nitrobenzylthioinosine Grünenthal GmbH (DE) 2003-10-15 EP disclosed
US-20030147844-A1 Polymeric thiol-linked prodrugs BELROSE PHARMA INC. 2003-08-07 US disclosed
WO-2003039479-A2 POLYMERIC THIOL-LINKED PRODRUGS ENZON, INC. (US) 2003-05-15 WO disclosed
WO-2003035075-A1 INHIBITORS OF HUMAN PHOSPHATIDYL-INOSITOL 3-KINASE DELTA ICOS CORPORATION (US) 2003-05-01 WO disclosed
US-6518277-B1 Disrupting leukocyte function ICOS CORPORATION 2003-02-11 US disclosed
EP-1278748-A2 INHIBITORS OF HUMAN PHOSPHATIDYL-INOSITOL 3-KINASE DELTA ICOS CORPORATION (US) 2003-01-29 EP disclosed
US-20020161014-A1 Purinyl substituted quinazoline-4-one derivatives ICOS CORPORATION, A DELAWARE CORPORATION 2002-10-31 US disclosed
WO-2001081346-A2 INHIBITORS OF HUMAN PHOSPHATIDYL-INOSITOL 3-KINASE DELTA ICOS CORPORATION (US) 2001-11-01 WO disclosed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP disclosed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP disclosed
EP-0673783-B1 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORP (US) 2000-07-05 EP disclosed
US-5659348-A APPLYING TO A SUBSTRATE XEROX CORPORATION (US) 1997-08-19 US disclosed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP disclosed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP disclosed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US disclosed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US disclosed
EP-0673783-A2 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORPORATION (US) 1995-09-27 EP disclosed
EP-0397529-B1 Photohardenable electrostatic element with improved environmental latitude DU PONT (US) 1994-11-23 EP disclosed
EP-0343666-B1 Correct-reading images from photopolymer electrographic master DU PONT (US) 1994-08-03 EP disclosed
EP-0352774-B1 Photopolymerisation sensitizer active at longer wavelength DU PONT (US) 1994-06-22 EP disclosed
US-5288528-A Decomposing, repolymerizing additoin polymers; chain transfer agent or initiator present; molecular weight control E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-02-22 US disclosed
EP-0331511-B1 6-SUBSTITUTED PURINYL PIPERAZINE DERIVATIVES ORTHO PHARMACEUTICAL CORPORATION (US) 1993-07-28 EP disclosed
US-5164390-A Cardiac disorders ORTHO PHARMACEUTICAL CORPORATION (US) 1992-11-17 US disclosed
US-5145760-A POSITIVE-WORKING PHOTOSENSITIVE ELECTROSTATIC MASTER WITH IMPROVED INVIRONMENTAL LATITUDE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-09-08 US disclosed
EP-0186454-B1 6-PURINYL N-(2-CHLOROETHYL) CARBAMATE AND THIOCARBAMATE, A PROCESS FOR THEIR PREPARATION AND USE THEREOF SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu (CS) 1992-04-08 EP disclosed
US-5096790-A Cyclopentanone, 2,5-bis-(benzo(i,j)quinolizine)methylene, photoresist E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-03-17 US disclosed
US-5066652-A ANTIULCER AGENTS CHIESI FARMACEUTICI S.P.A. (IT) 1991-11-19 US disclosed
US-5064740-A Binder blend, masters/duplication/; good electrostatic and electroconductive properties E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-11-12 US disclosed
EP-0454385-A1 Process for preparing optically active isomers of 6-substituted purinyl piperazine derivatives ORTHO PHARMACEUTICAL CORPORATION (US) 1991-10-30 EP disclosed
US-5043237-A Inhibitor-containing photohardenable electrostatic master compositions having improved resolution E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-08-27 US disclosed
WO-1991011031-A1 PROCESSES FOR MAKING THIN FILMS AND CIRCUIT ELEMENTS OF HIGH TEMPERATURE SUPERCONDUCTORS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-07-25 WO disclosed
EP-0436948-A2 Inhibitor-containing photohardenable compositions having improved resolution E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-07-17 EP disclosed
US-5028503-A Photohardenable electrostatic element with improved backtransfer characteristics E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-07-02 US disclosed
US-5021574-A Cardiotonic agents, antiarrhythmia agents ORTHO PHARMACEUTICAL CORPORATION (US) 1991-06-04 US disclosed
US-5006434-A Blend of binders with different glass transition temperatures, heat and moisture resistance E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-04-09 US disclosed
EP-0418855-A1 Photohardenable electrostatic element with improved backtransfer characteristics E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-03-27 EP disclosed
US-4987230-A DERIVED FROM CYCLIC KETONES AND TRICYCLIC AMINOALDEHYDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-01-22 US disclosed
EP-0405543-A2 Photosensitive leuco dye containing electrostatic master with printout image E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-01-02 EP disclosed
EP-0397529-A2 Photohardenable electrostatic element with improved environmental latitude E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-11-14 EP disclosed
EP-0390103-A2 High resolution superimposed images from photopolymer electrographic master E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-10-03 EP disclosed
US-4960660-A RADIATION EXPOSURE, STRIPPING COVER SHEET, LAMINATION, PEELING TEMPORARY SURFACE, CHARGING, DEVELOPING E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-10-02 US disclosed
US-4945020-A MIXTURE OF POLYMIERC BINDER, PHOTOOXIDANT, LEUCO DYE, HALOGENATED HYDROCARBON AND PLASTICIZER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-07-31 US disclosed
EP-0374875-A2 Visible sensitizers for photopolymerizable compositions E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-06-27 EP disclosed
US-4917977-A METHINE DYE, ETHYLENICALLY UNSATURATED COMPOUND AND FREE RADICAL GENERATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-04-17 US disclosed
EP-0352774-A1 Photopolymerisation sensitizer active at longer wavelength E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-01-31 EP disclosed
US-4897327-A Correct-reading images from photopolymer electrographic master E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-01-30 US disclosed
EP-0343666-A2 Correct-reading images from photopolymer electrographic master E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-11-29 EP disclosed
US-4876257-A 6-Substituted purinyl piperazine derivatives useful as cardiotonic and antiarrhythmic agents ORTHO PHARMACEUTICAL CORPORATION (US) 1989-10-24 US disclosed
EP-0331511-A1 6-Substituted purinyl piperazine derivatives ORTHO PHARMACEUTICAL CORPORATION (US) 1989-09-06 EP disclosed
US-4859551-A Process for preparing positive and negative images using photohardenable electrostatic master E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-08-22 US disclosed
US-4849314-A PHOTOPOLYMERIZATION E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-07-18 US disclosed
EP-0315120-A2 Photohardenable electrostatic master having improved backtransfer and charge decay E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-05-10 EP disclosed
EP-0315121-A2 Process for preparing positive and negative images using photohardenable electrostatic master E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-05-10 EP disclosed
EP-0315116-A2 Photohardenable electrostatic master containing electron acceptor or donor E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-05-10 EP disclosed
US-4818660-A POLYMERIC BINDER AND UNSATURATED COMPOUND, PHOTOINITIATOR, BAS IC DYE, LEUCO DYE AND STRONG ACID E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-04-04 US disclosed
EP-0301422-A2 Thiomethyl and sulfinylmethyl derivatives having gastric acid antisecretory activity, processes for the preparation thereof and pharmaceutical compositions containing them CHIESI FARMACEUTICI S.p.A. (IT) 1989-02-01 EP disclosed
US-4732831-A MONOMERS, TONERS, CHAIN TRANSFER AGENTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-03-22 US disclosed
US-4720497-A 6-purinyl N-/2-chloroethyl/carbamate and thiocarbamate and process for the preparation thereof SPOFA, SPOJENE PODNIKY PRO ZDRAVOTNICKOU VYROBU (CS) 1988-01-19 US disclosed
EP-0243934-A2 Xeroprinting with photopolymer master E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-11-04 EP disclosed
EP-0071282-B1 URACIL DERIVATIVES AND USE THEREOF IN PHOTOGRAPHIC PRODUCTS AND PROCESSES POLAROID CORPORATION (US) 1986-09-24 EP disclosed
EP-0186454-A2 6-Purinyl N-(2-chloroethyl) carbamate and thiocarbamate, a process for their preparation and use thereof SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu (CS) 1986-07-02 EP disclosed
US-4442290-A DERIVATIVES OF PYRIMIDINEDIONE POLAROID CORPORATION (US) 1984-04-10 US disclosed
EP-0071282-A2 Uracil derivatives and use thereof in photographic products and processes POLAROID CORPORATION (US) 1983-02-09 EP disclosed
US-4350754-A FOR PHOTOGRAPHIC FILMS; URACIL DERIVATIVES POLAROID CORPORATION (US) 1982-09-21 US disclosed
US-4350754-A FOR PHOTOGRAPHIC FILMS; URACIL DERIVATIVES POLAROID CORPORATION (US) 1982-09-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (47 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070259889-A1 Protein Binding Compounds FABP1, FABP3, FABP2 PI4KA 4618/4885PI4K2B 4565/4885PI4K2A 4742/4885
US-20200048265-A1 HETEROCYCLIC COMPOUNDS AND THEIR USES MCL1, BCL9, MALT1 PI4KA 80/4885PI4K2B 173/4885PI4K2A 191/4885
US-20100152211-A1 INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA PIK3CD, PIK3CA, PIK3CG PI4KA 5/4885PI4K2B 11/4885PI4K2A 15/4885
US-20240024329-A1 COMBINATION DRUG PRODUCTS FOR TREATING PATIENTS SUFFERING FROM ONE OR MORE MEDICAL CONDITIONS CAUSED BY CORONAVIRUS INFECTION, INCLUDING BY SARS-CoV-2, ITS ALPHA, BETA, DELTA, OR OMICRON VARIANTS AND SUB VARIANTS TPMT, DDX6, MTAP PI4KA 4644/4885PI4K2B 4497/4885PI4K2A 4578/4885
US-20080103110-A1 Compounds ATIC, CDA, PAICS PI4KA 3502/4885PI4K2B 4175/4885PI4K2A 4105/4885
US-20170340633-A1 INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA PIK3CD, PIK3CA, PIK3CG PI4KA 5/4885PI4K2B 11/4885PI4K2A 15/4885
US-20050096293-A1 Analogs of nitrobenzylthioinosine NUDT1, TYMP, NNMT PI4KA 2857/4885PI4K2B 2555/4885PI4K2A 2812/4885
US-10645936-B2 Bacillus megaterium bioactive compositions and metabolites GZMB, VIP, BAX PI4KA 1375/4885PI4K2B 587/4885PI4K2A 1321/4885
US-20100168139-A1 INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA PIK3CD, PIK3CA, PIK3CG PI4KA 5/4885PI4K2B 11/4885PI4K2A 15/4885
US-20090137581-A1 Heterocyclic compounds and their uses MCL1, BCL9, MALT1 PI4KA 80/4885PI4K2B 173/4885PI4K2A 191/4885
US-20180360832-A1 INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA PIK3CD, PIK3CA, PIK3CG PI4KA 5/4885PI4K2B 11/4885PI4K2A 15/4885
US-20200267991-A1 BACILLUS MEGATERIUM BIOACTIVE COMPOSITIONS AND METABOLITES GZMB, VIP, BAX PI4KA 1375/4885PI4K2B 587/4885PI4K2A 1321/4885
US-20140154772-A1 INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA PIK3CD, PIK3CA, PIK3CG PI4KA 5/4885PI4K2B 11/4885PI4K2A 15/4885
US-20120220586-A1 HETEROCYCLIC COMPOUNDS AND THEIR USES MCL1, BCL9, MALT1 PI4KA 80/4885PI4K2B 173/4885PI4K2A 191/4885
US-20120135994-A1 INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA PIK3CD, PIK3CA, PIK3CG PI4KA 5/4885PI4K2B 11/4885PI4K2A 15/4885
US-20140051571-A1 BACILLUS MEGATERIUM BIOACTIVE COMPOSITIONS AND METABOLITES GZMB, VIP, BAX PI4KA 1375/4885PI4K2B 587/4885PI4K2A 1321/4885
US-20100216820-A1 THIENOPYRIMIDIONES FOR TREATMENT OF INFLAMMATORY DISORDERS AND CANCERS PIK3CA, PIK3CD, PIK3CB PI4KA 16/4885PI4K2B 31/4885PI4K2A 51/4885
US-20020161014-A1 Purinyl substituted quinazoline-4-one derivatives PIK3CD, PIK3CA, PIK3CG PI4KA 6/4885PI4K2B 22/4885PI4K2A 20/4885
US-11986479-B2 Combination drug products for treating patients suffering from one or more medical conditions caused by coronavirus infection, including by SARS-CoV-2, its alpha, beta, delta, or omicron variants and sub variants TPMT, DDX6, MTAP PI4KA 4644/4885PI4K2B 4497/4885PI4K2A 4578/4885
US-20150045361-A1 HETEROCYCLIC COMPOUNDS AND THEIR USES MCL1, BCL9, MALT1 PI4KA 80/4885PI4K2B 173/4885PI4K2A 191/4885
US-20110021541-A1 INHIBITORS OF HUMAN PHOSPHATIDYL-INOSITOL 3-KINASE DELTA PIK3CD, PI4KB, PI4KA PI4KA 3/4885PI4K2B 7/4885PI4K2A 12/4885
US-20170049772-A1 INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA PIK3CD, PIK3CA, PIK3CG PI4KA 4/4885PI4K2B 11/4885PI4K2A 12/4885
US-20050261317-A1 Inhibitors of human phosphatidylinositol 3-kinase delta PIK3CD, PIK3R5, PIK3CA PI4KA 6/4885PI4K2B 18/4885PI4K2A 23/4885
US-20040266780-A1 for example, 2-(6-aminopurin-9-ylmethyl)-3-(2-chlorophenyl)-6,7-dimethoxy-3H-quinazolin-4-one PIK3CD, PIK3CA, PIK3CG PI4KA 10/4885PI4K2B 18/4885PI4K2A 27/4885
US-20180105532-A1 HETEROCYCLIC COMPOUNDS AND THEIR USES MCL1, BCL9, MALT1 PI4KA 80/4885PI4K2B 173/4885PI4K2A 191/4885
US-20200093828-A1 CDC-7-INHIBITOR COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS CDC7, TARDBP, CDC14A PI4KA 620/4885PI4K2B 704/4885PI4K2A 650/4885
US-11446304-B2 CDC-7-inhibitor compounds and use thereof for the treatment of neurological conditions CDC7, TARDBP, CDC14A PI4KA 620/4885PI4K2B 704/4885PI4K2A 650/4885
US-20120172591-A1 INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA PIK3CD, PIK3CA, PIK3CG PI4KA 5/4885PI4K2B 11/4885PI4K2A 15/4885
US-20200061062-A1 INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA PIK3CD, PIK3CA, PIK3CG PI4KA 5/4885PI4K2B 11/4885PI4K2A 15/4885
US-11959065-B2 Bacillus megaterium bioactive compositions and metabolites GZMB, VIP, BAX PI4KA 1375/4885PI4K2B 587/4885PI4K2A 1321/4885
US-20210346388-A1 CDC7-Inhibiting Purine Derivatives and their use for the Treatment of Neurological Conditions CDC7, TARDBP, TDP1 PI4KA 1151/4885PI4K2B 918/4885PI4K2A 924/4885
US-20070099871-A1 Bioreductively-activated prodrugs CBR3, OPRD1, CBR1 PI4KA 3567/4885PI4K2B 3535/4885PI4K2A 4107/4885
US-20150305346-A1 BACILLUS MEGATERIUM BIOACTIVE COMPOSITIONS AND METABOLITES GZMB, VIP, BAX PI4KA 1375/4885PI4K2B 587/4885PI4K2A 1321/4885
US-20120220585-A1 HETEROCYCLIC COMPOUNDS AND THEIR USES MCL1, BCL9, MALT1 PI4KA 80/4885PI4K2B 173/4885PI4K2A 191/4885
US-20070142370-A1 Azabicyclooctan-3-one derivatives and use thereof CCNA1, CCNY, MALT1 PI4KA 1818/4885PI4K2B 1430/4885PI4K2A 1858/4885
US-20220315885-A1 BACILLUS MEGATERIUM BIOACTIVE COMPOSITIONS AND METABOLITES GZMB, VIP, BAX PI4KA 1375/4885PI4K2B 587/4885PI4K2A 1321/4885
US-20030195211-A1 Inhibitors of human phosphatidylinositol 3-kinase delta PIK3CD, PIK3CA, PIK3CG PI4KA 5/4885PI4K2B 11/4885PI4K2A 16/4885
US-20240115705-A1 Regulation of Butyrophilin subfamily 3 member A1 (BTN3A1, CD277) BTN3A1, BTF3, CD274 PI4KA 3505/4885PI4K2B 3576/4885PI4K2A 3334/4885
US-20210060016-A1 ANTICANCER AGENT MAP2, TNKS, TNKS1BP1 PI4KA 1064/4885PI4K2B 1104/4885PI4K2A 968/4885
US-10695349-B2 Inhibitors of human phosphatidylinositol 3-kinase delta PIK3CD, PIK3CA, PIK3CG PI4KA 5/4885PI4K2B 11/4885PI4K2A 15/4885
US-10010550-B2 Inhibitors of human phosphatidylinositol 3-kinase delta PIK3CD, PIK3CA, PIK3CG PI4KA 5/4885PI4K2B 11/4885PI4K2A 15/4885
US-11384332-B2 Bacillus megaterium bioactive compositions and metabolites GZMB, VIP, BAX PI4KA 1375/4885PI4K2B 587/4885PI4K2A 1321/4885
US-20170198335-A1 Stabilization of Non-Denatured Polypeptides, Nucleic Acids, and Exosomes in a Blood Sample at Ambient Temperatures EXOSC5, EXOSC9, EXOSC10 PI4KA 3429/4885PI4K2B 3497/4885PI4K2A 2974/4885
US-10398695-B2 Inhibitors of human phosphatidylinositol 3-kinase delta PIK3CD, PIK3CA, PIK3CG PI4KA 5/4885PI4K2B 11/4885PI4K2A 15/4885
US-20180042241-A1 BACILLUS MEGATERIUM BIOACTIVE COMPOSITIONS AND METABOLITES GZMB, VIP, BAX PI4KA 1375/4885PI4K2B 587/4885PI4K2A 1321/4885
US-20150166549-A1 ISOCHROMENE DERIVATIVES AS PHOSHOINOSITIDE 3-KINASES INHIBITORS PIKFYVE, IP6K2, IP6K3 PI4KA 17/4885PI4K2B 18/4885PI4K2A 20/4885
US-20030147844-A1 Polymeric thiol-linked prodrugs MPST, TST, SHMT1 PI4KA 3477/4885PI4K2B 3504/4885PI4K2A 3442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.