Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | LAP3 | P28838 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27523678 | 1.00 | — | — | |
| Ethane SCHEMBL27645934 | 0.96 | TSHR (0.41) | TSHRLAP3KDM4EMAPK1TDP1 | |
| Hydrochloric Acid SCHEMBL27520761 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL1189441 | 0.96 | — | — | |
| Ammonia Solution, Strong SCHEMBL3718561 | 0.96 | — | — | |
| Ammonia Solution, Strong SCHEMBL1550394 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL4345954 | 0.96 | — | — | |
| SCHEMBL1217603 | 0.92 | — | — | |
| SCHEMBL15226 | 0.92 | — | — | |
| SCHEMBL1127507 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 252 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230414478-A1 | HAIR CLEANSER COMPOSITION, METHODS AND USES THEREOF | K18, INC. | 2023-12-28 | — | — | US | claimed |
| US-20230414479-A1 | DETOX HAIR AND SCALP CLEANSER COMPOSITION, METHODS AND USES THEREOF | K18, INC. | 2023-12-28 | — | — | US | claimed |
| WO-2023250104-A2 | DETOX HAIR AND SCALP CLEANSER COMPOSITION, METHODS AND USES THEREOF | K18, INC. (US) | 2023-12-28 | — | — | WO | claimed |
| WO-2023250105-A1 | HAIR CLEANSER COMPOSITION, METHODS AND USES THEREOF | K18, INC. (US) | 2023-12-28 | — | — | WO | claimed |
| US-20070256987-A1 | Chemically-enhanced mechanical treatment of water | AQUALON COMPANY | 2007-11-08 | — | — | US | claimed |
| WO-2007075681-A1 | CHEMICALLY-ENHANCED MECHANICAL TREATMENT OF WATER | HERCULES INCORPORATED (US) | 2007-07-05 | — | — | WO | claimed |
| EP-1001731-B1 | DECORATIVE COSMETIC O/W EMULSION | LANCASTER GROUP GMBH (DE) | 2004-05-12 | — | — | EP | claimed |
| JP-4364111-A | — | — | None | — | — | JP | disclosed |
| EP-4363401-A1 | BIO-BASED ISETHIONATE COMPOUNDS | Clariant International Ltd (CH) | 2024-05-08 | — | — | EP | disclosed |
| US-11975088-B2 | Personal care composition | DOW GLOBAL TECHNOLOGIES LLC (US) | 2024-05-07 | — | — | US | disclosed |
| WO-2024074409-A1 | COMBINATION COMPRISING A GLUCAMIDE AND A CO-EMULSIFIER | CLARIANT INTERNATIONAL LTD (CH) | 2024-04-11 | — | — | WO | disclosed |
| WO-2024074693-A1 | BIO-BASED ANTIMICROBIAL COMPOUNDS | CLARIANT INTERNATIONAL LTD (CH) | 2024-04-11 | — | — | WO | disclosed |
| US-20240115476-A1 | COMPOSITIONS COMPRISING A MULTI-TAIL SURFACTANT AND A CATIONIC POLYMER AND USES | RHODA OPERATIONS (FR) | 2024-04-11 | — | — | US | disclosed |
| US-5283228-A | Agrichemical and polymer having pendant hydroxy and amino groups; pollution control | ISP INVESTMENTS, INC. (US) | 1994-02-01 | — | — | US | disclosed |
| EP-0579729-A1 | QUATERNARY AMMONIUM ANTIBACTERIAL DENTIFRICES WITH SELECTED CALCIUM ABRASIVES | SMITHKLINE BEECHAM CORPORATION (US) | 1994-01-26 | — | — | EP | disclosed |
| WO-1993016592-A1 | LEACHING INHIBITION OF CROP TREATING CHEMICALS WITH POLYMERS | ISP INVESTMENTS INC. (US) | 1993-09-02 | — | — | WO | disclosed |
| US-5202048-A | Personal cleansing product with odor compatible bulky amine cationic polymer with reduced odor characteristics | THE PROCTER & GAMBLE COMPANY (US) | 1993-04-13 | — | — | US | disclosed |
| US-5176901-A | Cationic Quaternary Ammonium Bactericides | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-05 | — | — | US | disclosed |
| JP-H04364111-A | AQUEOUS SHAMPOO COMPOSITION AND HAIR-DRESSING USING THE SAME | UNILEVER NV | 1992-12-16 | — | — | JP | disclosed |
| WO-1992018096-A1 | QUATERNARY AMMONIUM ANTIBACTERIAL DENTIFRICES WITH SELECTED CALCIUM ABRASIVES | SMITHKLINE BEECHAM CORPORATION (US) | 1992-10-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11975088-B2 | Personal care composition | MMS19, TRIB1, ASIC1 | TSHR 3882/4885LAP3 3363/4885KDM4E 1775/4885 |
| US-20240115476-A1 | COMPOSITIONS COMPRISING A MULTI-TAIL SURFACTANT AND A CATIONIC POLYMER AND USES | PHOSPHO1, SGMS1, SGMS2 | TSHR 4379/4885LAP3 2272/4885KDM4E 4146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.