Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acrylic Acid Ethyl Ester. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid Ethyl Ester SCHEMBL3626767 | 0.98 | ALDH1A1 (0.52) | ALDH1A1TSHRPOLBL3MBTL1LMNA | |
| Acrylic Acid Ethyl Ester SCHEMBL631102 | 0.90 | ACHE (0.46) | ALDH1A1POLBRAB9ANPC1SMN1; SMN2 | |
| Acrylic Acid Ethyl Ester SCHEMBL4608831 | 0.90 | ALDH1A1 (0.42) | ALDH1A1TSHRPOLBL3MBTL1LMNA | |
| Acrylic Acid Ethyl Ester SCHEMBL3935582 | 0.88 | ACHE (0.47) | ALDH1A1POLBRAB9ANPC1 | |
| (Chloromethyl)Benzene SCHEMBL7046858 | 0.86 | ACHE (0.44) | ALDH1A1TSHRPOLBSMN1; SMN2 | |
| Acrylic Acid Methyl Ester SCHEMBL27606783 | 0.85 | ALDH1A1 (0.53) | ALDH1A1TSHRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2518739 | 0.83 | THRB (0.49) | ALDH1A1TSHRPOLBL3MBTL1RAB9A | |
| Urethane SCHEMBL28751548 | 0.83 | ALDH1A1 (0.47) | ALDH1A1TSHRPOLBL3MBTL1LMNA | |
| Acrylic Acid SCHEMBL11072293 | 0.82 | ALDH1A1 (0.63) | ALDH1A1TSHRLMNARAB9ANPC1 | |
| Acrylic Acid SCHEMBL11072291 | 0.82 | ALDH1A1 (0.63) | ALDH1A1TSHRLMNARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101861342-B | High definition printing with waterborne inks on non-porous substrates | RHODIA | 2012-11-21 | — | — | CN | claimed |
| EP-2209824-B1 | HIGH DEFINITION PRINTING WITH WATERBORNE INKS ON NON-POROUS SUBSTRATES | RHODIA (US) | 2012-08-08 | — | — | EP | claimed |
| US-8025918-B2 | High definition printing with waterborne inks on non-porous substrates | RHODIA, INC. (US) | 2011-09-27 | — | — | US | claimed |
| CN-101861342-A | High definition printing with waterborne inks on non-porous substrates | RHODIA | 2010-10-13 | — | — | CN | claimed |
| US-20090130295-A1 | High Definition Printing With Waterborne Inks on Non-Porous Substrates | RHODIA OPERATIONS (FR) | 2009-05-21 | — | — | US | claimed |
| CN-114466955-A | Polymer dispersions suitable for fabric conditioning treatment | 罗地亚经营管理公司 | 2022-05-10 | — | — | CN | disclosed |
| EP-3673990-A1 | CHROMATOGRAPHY PACKING FOR SEPARATION AND/OR DETECTION OF METHYLATED DNA | Sekisui Medical Co., Ltd. (JP) | 2020-07-01 | — | — | EP | disclosed |
| US-20200172971-A1 | CHROMATOGRAPHY PACKING FOR SEPARATION AND/OR DETECTION OF METHYLATED DNA | SEKISUI MEDICAL CO., LTD. (JP) | 2020-06-04 | — | — | US | disclosed |
| CN-110753707-A | Polymer dispersions for wax inhibition | 罗地亚经营管理公司 | 2020-02-04 | — | — | CN | disclosed |
| CN-105911183-B | The method for separating and detecting of ion-exchange chromatography filler and nucleic acid chains | 积水医疗株式会社 | 2019-03-22 | — | — | CN | disclosed |
| CN-108138163-A | Method for determining tumor | 公益财团法人癌研究会 | 2018-06-08 | — | — | CN | disclosed |
| CN-108026586-A | Method for determining prognosis of renal cell carcinoma | 国立研究开发法人国立癌研究中心 | 2018-05-11 | — | — | CN | disclosed |
| US-6869647-B2 | Print media products for generating high quality, water-fast images and methods for making the same | HEWLETT-PACKARD DEVELOPMENT COMPANY L.P. (US) | 2005-03-22 | — | — | US | disclosed |
| US-6844035-B2 | Print media products for generating high quality images and methods for making the same | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2005-01-18 | — | — | US | disclosed |
| US-20040161555-A1 | Print media products for generating high quality images and methods for making the same | NIU BOR-JIUNN (US) | 2004-08-19 | — | — | US | disclosed |
| US-6689433-B2 | THREE BINDERS: GELATIN, A POLY(VINYL ALCOHOL-ETHYLENE OXIDE) COPOLYMER, AND A POLY((STYRENE)-(N-BUTYL ACRYLATE)-(METHYL METHACRYLATE)-(2-(TERT-BUTYLAMINO) ETHYL METHACRYLATE)) COPOLYMER | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2004-02-10 | — | — | US | disclosed |
| EP-1361072-A2 | Print media products for generating high quality images and methods for making the same | Hewlett-Packard Company (US) | 2003-11-12 | — | — | EP | disclosed |
| US-20030207052-A1 | PRINT MEDIA PRODUCTS FOR GENERATING HIGH QUALITY IMAGES AND METHODS FOR MAKING THE SAME | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2003-11-06 | — | — | US | disclosed |
| US-20030049417-A1 | Print media products for generating high quality, water-fast images and methods for making the same | HEWLETT-PACKARD DEVELOPMENT COMPANY L.P. | 2003-03-13 | — | — | US | disclosed |
| EP-1288013-A2 | Print media products for generating high quality, water-fast images and methods for making the same | Hewlett-Packard Company (US) | 2003-03-05 | — | — | EP | disclosed |