Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Trimethylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.41 |
| ▸ | MMP1 known ✓ | P03956 | 1/20 | 0.38 |
| ▸ | CHRNB4 known ✓ | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 known ✓ | P32297 | 1/20 | 0.35 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trimethylammonium SCHEMBL635942 | 1.00 | NPC1 (0.41) | NPC1GAAMAPTRAB9ASMN1; SMN2 | |
| Trimethylammonium SCHEMBL28199923 | 0.98 | NPC1 (0.40) | NPC1GAAMAPTRAB9ASMN1; SMN2 | |
| Trimethylammonium SCHEMBL21743 | 0.98 | NPC1 (0.42) | NPC1GAAMAPTRAB9ASMN1; SMN2 | |
| Acetic Acid SCHEMBL9389723 | 0.96 | NPC1 (0.39) | NPC1GAAMAPTRAB9ASMN1; SMN2 | |
| Trimethylammonium SCHEMBL27347511 | 0.96 | NPC1 (0.41) | NPC1GAAMAPTRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3148805 | 0.94 | MMP1 (0.41) | NPC1GAAMAPTRAB9ASMN1; SMN2 | |
| N,N-Dimethylethanaminium SCHEMBL7062326 | 0.92 | NPC1 (0.39) | NPC1GAAMAPTRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28010702 | 0.91 | MMP1 (0.40) | NPC1GAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL149370 | 0.91 | — | — | |
| N,N-Dimethylethanaminium SCHEMBL446053 | 0.90 | NPC1 (0.40) | NPC1GAAMAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117186857-A | Gel breaking temporary plugging liquid and preparation method and application thereof | 中国石油天然气股份有限公司 | 2023-12-08 | — | — | CN | claimed |
| US-11793198-B2 | Disinfectant composition | THE PROCTER & GAMBLE COMPANY (US) | 2023-10-24 | — | — | US | claimed |
| CN-114080156-B | Disinfectant composition | 宝洁公司 | 2023-05-23 | — | — | CN | claimed |
| CN-115678440-B | OCA optical cement for 3D curved screen and preparation method and application thereof | 广州鹿山新材料股份有限公司 | 2023-03-21 | — | — | CN | claimed |
| US-20230056285-A1 | DISINFECTANT COMPOSITION | PROCTER & GAMBLE (US) | 2023-02-23 | — | — | US | claimed |
| CN-115678440-A | OCA optical adhesive for 3D curved screen and preparation method and application thereof | 广州鹿山新材料股份有限公司 | 2023-02-03 | — | — | CN | claimed |
| CN-114736393-A | Conductive hydrogel and preparation method and application thereof | 浙江清华柔性电子技术研究院 | 2022-07-12 | — | — | CN | claimed |
| CN-114080156-A | Disinfectant composition | 宝洁公司 | 2022-02-22 | — | — | CN | claimed |
| CN-114040677-A | Disinfectant composition | 宝洁公司 | 2022-02-11 | — | — | CN | claimed |
| CN-110161243-B | Nano artificial antibody inhibitor for real-time imaging of tumor marker in living cell and preparation method thereof | 北京化工大学 | 2021-05-04 | — | — | CN | claimed |
| WO-2012061305-A1 | SURFACE APPLICATION OF POLYMERS TO IMPROVE PAPER STRENGTH | HERCULES INCORPORATED (US) | 2012-05-10 | — | — | WO | claimed |
| US-20120111517-A1 | Surface Application of Polymers to Improve Paper Strength | THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A., AS NOTES COLLATERAL AGENT | 2012-05-10 | — | — | US | claimed |
| US-7807766-B2 | Polymers for use in cleaning compositions | COGNIS IP MANAGEMENT GMBH (DE) | 2010-10-05 | — | — | US | claimed |
| US-20070179265-A1 | POLYMERS FOR USE IN CLEANING COMPOSITIONS | COGNIS IP MANAGEMENT GMBH (DE) | 2007-08-02 | — | — | US | claimed |
| EP-1539846-A1 | GRAFT COPOLYMERS, THEIR PREPARATION AND USE IN CAPILLARY ELECTROPHORESIS | Applera Corporation (US) | 2005-06-15 | — | — | EP | claimed |
| WO-2004011513-A1 | GRAFT COPOLYMERS, THEIR PREPARATION AND USE IN CAPILLARY ELECTROPHORESIS | APPLERA CORPORATION (US) | 2004-02-05 | — | — | WO | claimed |
| US-6656507-B2 | Mixture of polymethacrylate and carboxymethyl cellulose | ROEHM GMBH & CO. KG (DE) | 2003-12-02 | — | — | US | claimed |
| US-20010055619-A1 | AQUEOUS DISPERSION SUITABLE FOR THE PRODUCTION OF COATINGS AND BINDERS FOR SOLID ORAL DRUGS | ROHM GMBH (DE) | 2001-12-27 | — | — | US | claimed |
| US-6049733-A | Electrotransport system with ion exchange material competitive ion capture | ALZA CORPORATION (US) | 2000-04-11 | — | — | US | claimed |
| US-5180757-A | Curable acrylate monomers with photoinitiators for printing inks and protective coatings | MLT/MICRO-LITE TECHNOLOGY CORPORATION | 1993-01-19 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11793198-B2 | Disinfectant composition | ALKBH1, ALKBH5, POLL | GAA 2404/4885MMP1 2973/4885CHRNB4 4625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.