Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of 4-Phenyl-Butylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA known ✓ | P21397 | 1/20 | 0.95 |
| ▸ | HTR2A known ✓ | P28223 | 2/20 | 0.67 |
| ▸ | MAOB known ✓ | P27338 | 2/20 | 0.64 |
| ▸ | SIGMAR1 known ✓ | Q99720 | 3/20 | 0.60 |
| ▸ | HRH1 known ✓ | P35367 | 4/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.64 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29046414 | 0.98 | MAOA (0.91) | MAOAHTR2AMAOBCYP2A6SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5154319 | 0.98 | MAOA (0.91) | MAOAHTR2AMAOBCYP2A6SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11507504 | 0.98 | MAOA (0.91) | MAOAHTR2AMAOBCYP2A6SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6250106 | 0.98 | MAOA (0.91) | MAOAHTR2AMAOBCYP2A6SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4621628 | 0.98 | MAOA (0.91) | MAOAHTR2AMAOBCYP2A6SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4317782 | 0.98 | MAOA (0.91) | MAOAHTR2AMAOBCYP2A6SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1072929 | 0.98 | MAOA (0.91) | MAOAHTR2AMAOBCYP2A6SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5157586 | 0.98 | MAOA (0.91) | MAOAHTR2AMAOBCYP2A6SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9765791 | 0.98 | MAOA (0.91) | MAOAHTR2AMAOBCYP2A6SMN1; SMN2 | |
| 4-Phenyl-Butylamine SCHEMBL132472 | 0.97 | MAOA (1.00) | MAOAHTR2AMAOBCYP2A6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120004313-A | Organic molecule intercalated vanadium oxide positive electrode material, and preparation method and application thereof | 成都大学 | 2025-05-16 | — | — | CN | claimed |
| CN-116193878-A | Amine halide salt doped carbon-based perovskite solar cell | 河北工业大学 | 2023-05-30 | — | — | CN | claimed |
| CN-115988889-A | Perovskite solar cell treated by ammonium chloride salt and preparation method thereof | 河北工业大学 | 2023-04-18 | — | — | CN | claimed |
| CN-104926842-A | Multiferroic compound and preparation method thereof | UNIV SUN YAT SEN | 2015-09-23 | — | — | CN | claimed |
| CN-120004313-A | Organic molecule intercalated vanadium oxide positive electrode material, and preparation method and application thereof | 成都大学 | 2025-05-16 | — | — | CN | disclosed |
| CN-120004313-A | Organic molecule intercalated vanadium oxide positive electrode material, and preparation method and application thereof | 成都大学 | 2025-05-16 | — | — | CN | disclosed |
| CN-116209334-A | Method for preparing red, green and blue color perovskite pixel array by ink-jet printing and application thereof | 华南理工大学 | 2023-06-02 | — | — | CN | disclosed |
| CN-116193878-A | Amine halide salt doped carbon-based perovskite solar cell | 河北工业大学 | 2023-05-30 | — | — | CN | disclosed |
| CN-115988889-A | Perovskite solar cell treated by ammonium chloride salt and preparation method thereof | 河北工业大学 | 2023-04-18 | — | — | CN | disclosed |
| US-20160122450-A1 | SYNTHESIS OF A SUBSTITUTED FURAN | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2016-05-05 | — | — | US | disclosed |
| CN-104926842-A | Multiferroic compound and preparation method thereof | UNIV SUN YAT SEN | 2015-09-23 | — | — | CN | disclosed |
| EP-0815856-A2 | Retroviral protease inhibitors | MONSANTO COMPANY (US) | 1998-01-07 | — | — | EP | disclosed |
| US-5703076-A | TREATING HIV, AIDS | G. D. SEARLE & CO. (US) | 1997-12-30 | — | — | US | disclosed |
| EP-0813868-A2 | Retroviral protease inhibitors | MONSANTO COMPANY (US) | 1997-12-29 | — | — | EP | disclosed |
| EP-0813867-A2 | Retroviral protease inhibitors | MONSANTO COMPANY (US) | 1997-12-29 | — | — | EP | disclosed |
| US-5698569-A | Retroviral protease inhibitors | G. D. SEARLE & CO. (US) | 1997-12-16 | — | — | US | disclosed |
| EP-0368750-B1 | Process for preparing substituted aminoanthraquinones | SUMITOMO CHEMICAL CO (JP) | 1994-10-26 | — | — | EP | disclosed |
| EP-0368750-A2 | Process for preparing substituted aminoanthraquinones | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-05-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160122450-A1 | SYNTHESIS OF A SUBSTITUTED FURAN | DCXR, PFAS, FUT6 | MAOA 1667/4885HTR2A 2806/4885MAOB 1928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.