Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 known ✓ | O15379 | 1/20 | 0.40 |
| ▸ | GAA known ✓ | P10253 | 2/20 | 0.39 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | EP300 | Q09472 | 2/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6854234 | 0.97 | IDO1 (0.42) | IDO1EP300HDAC3KAT2BKAT8 | |
| SCHEMBL9008984 | 0.94 | IDO1 (0.40) | IDO1EP300HDAC3KAT2BKAT8 | |
| Hydrochloric Acid SCHEMBL28756357 | 0.83 | ALOX15 (0.40) | IDO1EP300HDAC3KAT2BKAT8 | |
| Hydrochloric Acid SCHEMBL28281094 | 0.83 | ALOX15 (0.40) | IDO1EP300HDAC3KAT2BKAT8 | |
| SCHEMBL6853785 | 0.82 | EP300 (0.43) | IDO1EP300HDAC3KAT2BKAT8 | |
| SCHEMBL7855237 | 0.79 | ALOX15 (0.42) | IDO1EP300HDAC3KAT2BKAT8 | |
| SCHEMBL29689091 | 0.79 | ALOX15 (0.42) | IDO1EP300HDAC3KAT2BKAT8 | |
| SCHEMBL8386315 | 0.77 | HPRT1 (0.58) | IDO1EP300HDAC3KAT2BKAT8 | |
| Hydrochloric Acid SCHEMBL829453 | 0.75 | PTPN22 (0.64) | IDO1EP300HDAC3KAT2BKAT8 | |
| SCHEMBL9833459 | 0.75 | PLAU (0.40) | IDO1EP300HDAC3KAT2BKAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0231373-B1 | A PROCESS FOR THE PRODUCTION OF A LIQUID CRYSTALLINE EXTENDED CHAIN POLYMER COMPOSITION | THE DOW CHEMICAL COMPANY (US) | 1991-01-30 | — | — | EP | claimed |
| EP-0119271-B1 | LIQUID CRYSTALLINE POLYMER COMPOSITIONS, PROCESS, AND PRODUCTS | SRI INTERNATIONAL (US) | 1990-07-11 | — | — | EP | claimed |
| EP-0231373-A4 | A PROCESS FOR THE PRODUCTION OF A LIQUID CRYSTALLINE EXTENDED CHAIN POLYMER COMPOSITION. | COMMTECH INTERNAT (US) | 1988-12-22 | — | — | EP | claimed |
| US-4772678-A | HIGH-MOLECULAR-WEIGHT CHAIN-EXTENDED N-HETEROCYCLIC POLYMERS PREPARED USING A NON-OXIDIZING STRONG ACID AS SOLVENT; HIGH-STRENGTH FIBERS, FILMS, FIBRIDS AND STRUCTURES | COMMTECH INTERNATIONAL MANAGEMENT CORPORATION (US) | 1988-09-20 | — | — | US | claimed |
| US-4703103-A | POLYPHOSPHORIC ACID CATALYST | COMMTECH INTERNATIONAL (US) | 1987-10-27 | — | — | US | claimed |
| EP-0231373-A1 | A PROCESS FOR THE PRODUCTION OF A LIQUID CRYSTALLINE EXTENDED CHAIN POLYMER COMPOSITION. | COMMTECH INT (US) | 1987-08-12 | — | — | EP | claimed |
| WO-1987000844-A1 | A PROCESS FOR THE PRODUCTION OF A LIQUID CRYSTALLINE EXTENDED CHAIN POLYMER COMPOSITION | COMMTECH INTERNATIONAL (US) | 1987-02-12 | — | — | WO | claimed |
| WO-1985004178-A1 | LIQUID CRYSTALLINE POLYMER COMPOSITIONS, PROCESS, AND PRODUCTS | SRI INTERNATIONAL (US) | 1985-09-26 | — | — | WO | claimed |
| US-4533693-A | ANISOTROPIC; FIBERS, FILMS | SRI INTERNATIONAL (US) | 1985-08-06 | — | — | US | claimed |
| EP-0119271-A4 | LIQUID CRYSTALLINE POLYMER COMPOSITIONS, PROCESS, AND PRODUCTS. | STANFORD RES INST INT (US) | 1985-07-01 | — | — | EP | claimed |
| EP-0119271-A1 | LIQUID CRYSTALLINE POLYMER COMPOSITIONS, PROCESS, AND PRODUCTS. | STANFORD RES INST INT (US) | 1984-09-26 | — | — | EP | claimed |
| EP-0119192-A1 | LIQUID CRYSTALLINE POLYMER COMPOSITIONS, PROCESS, AND PRODUCTS | SRI INTERNATIONAL (US) | 1984-09-26 | — | — | EP | claimed |
| WO-1984001160-A1 | LIQUID CRYSTALLINE POLYMER COMPOSITIONS, PROCESS, AND PRODUCTS | STANFORD RES INST INT (US) | 1984-03-29 | — | — | WO | claimed |
| WO-1984001162-A1 | LIQUID CRYSTALLINE POLYMER COMPOSITIONS, PROCESS, AND PRODUCTS | STANFORD RES INST INT (US) | 1984-03-29 | — | — | WO | claimed |
| EP-0231373-B1 | A PROCESS FOR THE PRODUCTION OF A LIQUID CRYSTALLINE EXTENDED CHAIN POLYMER COMPOSITION | THE DOW CHEMICAL COMPANY (US) | 1991-01-30 | — | — | EP | disclosed |
| EP-0231373-A4 | A PROCESS FOR THE PRODUCTION OF A LIQUID CRYSTALLINE EXTENDED CHAIN POLYMER COMPOSITION. | COMMTECH INTERNAT (US) | 1988-12-22 | — | — | EP | disclosed |
| US-4772678-A | HIGH-MOLECULAR-WEIGHT CHAIN-EXTENDED N-HETEROCYCLIC POLYMERS PREPARED USING A NON-OXIDIZING STRONG ACID AS SOLVENT; HIGH-STRENGTH FIBERS, FILMS, FIBRIDS AND STRUCTURES | COMMTECH INTERNATIONAL MANAGEMENT CORPORATION (US) | 1988-09-20 | — | — | US | disclosed |
| EP-0119202-A1 | LIQUID CRYSTALLINE POLY(2,6-BENZOTHIAZOLE) COMPOSITIONS, PROCESS AND PRODUCTS | SRI INTERNATIONAL (US) | 1984-09-26 | — | — | EP | disclosed |
| WO-1984001160-A1 | LIQUID CRYSTALLINE POLYMER COMPOSITIONS, PROCESS, AND PRODUCTS | STANFORD RES INST INT (US) | 1984-03-29 | — | — | WO | disclosed |
| WO-1984001161-A1 | LIQUID CRYSTALLINE POLY(2,6-BENZOTHIAZOLE) COMPOSITIONS, PROCESS AND PRODUCTS | STANFORD RES INST INT (US) | 1984-03-29 | — | — | WO | disclosed |