Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 4/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.67 |
| ▸ | MMP2 | P08253 | 4/20 | 0.62 |
| ▸ | MMP9 | P14780 | 4/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.62 |
| ▸ | MMP8 | P22894 | 2/20 | 0.62 |
| ▸ | APP | P05067 | 4/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.56 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | MMP13 | P45452 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | FDPS | P14324 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TTR | P02766 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15034413 | 0.87 | IAPP (0.67) | IAPPPTGS1MMP2MMP9NFKB1 | |
| SCHEMBL11928834 | 0.86 | IAPP (0.56) | IAPPPTGS1MMP2MMP9NFKB1 | |
| SCHEMBL29395741 | 0.85 | AKR1C3 (0.66) | IAPPPTGS1MMP2MMP9NFKB1 | |
| SCHEMBL13663908 | 0.85 | MMP9 (0.76) | IAPPPTGS1MMP2MMP9NFKB1 | |
| SCHEMBL2601403 | 0.85 | AKR1C3 (0.66) | IAPPPTGS1MMP2MMP9NFKB1 | |
| SCHEMBL12555874 | 0.85 | AKR1C3 (0.66) | IAPPPTGS1MMP2MMP9NFKB1 | |
| SCHEMBL14802240 | 0.84 | MMP9 (0.71) | IAPPPTGS1MMP2MMP9NFKB1 | |
| SCHEMBL12599489 | 0.84 | MMP9 (0.71) | IAPPPTGS1MMP2MMP9NFKB1 | |
| SCHEMBL15298278 | 0.84 | MMP9 (0.64) | IAPPPTGS1MMP2MMP9NFKB1 | |
| SCHEMBL15042796 | 0.83 | MMP2 (0.55) | IAPPPTGS1MMP2MMP9NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230364171-A1 | SENSORY MODIFIER COMPOUNDS | CARGILL, INCORPORATED (US) | 2023-11-16 | — | — | US | disclosed |
| US-20230364069-A1 | METHOD FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS THROUGH CO-ADMINISTRATION OF CURCUMIN DERIVATIVE AND TGF-B RECEPTOR INHIBITOR | UNIVERSITY INDUSTRY FOUNDATION, YONSEI UNIVERSITY WONJU CAMPUS (KR) | 2023-11-16 | — | — | US | disclosed |
| US-11717549-B2 | Steviol glycoside solubility enhancers | CARGILL, INCORPORATED (US) | 2023-08-08 | — | — | US | disclosed |
| US-11701400-B2 | Steviol glycoside compositions with reduced surface tension | CARGILL, INCORPORATED (US) | 2023-07-18 | — | — | US | disclosed |
| US-11654120-B2 | Composition for treating skin conditions | OLLIE'S HEALTH, LLC (US) | 2023-05-23 | — | — | US | disclosed |
| US-20230127708-A1 | GASIFIED SOLUTIONS WITH IMPROVED SENSORY PROPERTIES | CARGILL, INCORPORATED (US) | 2023-04-27 | — | — | US | disclosed |
| US-20230126688-A1 | Aqueous Formulation of Erythropoiesis Stimulating Protein Stabilised by Antioxidants for Parenteral Administration | AMGEN INC. | 2023-04-27 | — | — | US | disclosed |
| US-20230130823-A1 | PROCESS FOR THE PRODUCTION OF ANTITUMOUR PHARMACEUTICAL COMPOSITIONS USING PUSH-PULL BUTADIENES, COMPOUNDS AND USES THEREOF | ANHANGUERA EDUCACIONAL PARTICIPAÇÕES S/A (BR) | 2023-04-27 | — | — | US | disclosed |
| US-20180078535-A1 | THERAPEUTIC COMPOSITIONS CONTAINING HARMINE AND ISOVANILLIN COMPONENTS, AND METHODS OF USE THEREOF | IONS PHARMACEUTICAL S.À R.L. (LU) | 2018-03-22 | — | — | US | disclosed |
| US-9907786-B2 | Therapeutic compositions containing harmine and isovanillin components, and methods of use thereof | IONS PHARMACEUTICAL S.À R.L. (LU) | 2018-03-06 | — | — | US | disclosed |
| US-20150208705-A1 | ANTHOCYANIN COLOURING COMPOSITION | NESTEC S.A. (CH) | 2015-07-30 | — | — | US | disclosed |
| US-20150011494-A1 | THERAPEUTIC CURCUMIN DERIVATIVES | STC.UNM | 2015-01-08 | — | — | US | disclosed |
| US-20140294859-A1 | AQUEOUS FORMULATION OF ERYTHROPOIESIS STIMULATING PROTEIN STABILISED BY ANTIOXIDANTS FOR PARENTERAL ADMINISTRATION | AMGEN INC. (US) | 2014-10-02 | — | — | US | disclosed |
| US-20130237609-A1 | CELLULOSE DERIVATIVES FOR ENHANCING BIOAVAILABILITY OF FLAVONOIDS | EDGAR KEVIN J (US) | 2013-09-12 | — | — | US | disclosed |
| US-20130157986-A1 | NOVEL METHYLENEDIOXY PHENOLIC COMPOUNDS AND THEIR USE TO TREAT DISEASE | INVASC THERAPEUTICS, INC. (US) | 2013-06-20 | — | — | US | disclosed |
| US-20110123646-A1 | Extracts Obtained from Cell Line Cultures from Plants Belonging to the Oleaceae Family (e.g. Syringa Vulgaris), Their Preparation and Use | I.R.B. ISTITUTO DI RICERCHE BIOTECNOLOGICHE S.R.L. (IT) | 2011-05-26 | — | — | US | disclosed |
| US-20110123646-A1 | Extracts Obtained from Cell Line Cultures from Plants Belonging to the Oleaceae Family (e.g. Syringa Vulgaris), Their Preparation and Use | I.R.B. ISTITUTO DI RICERCHE BIOTECNOLOGICHE S.R.L. (IT) | 2011-05-26 | — | — | US | disclosed |
| US-7718199-B2 | Extracts obtained from cell line cultures from plants belonging to the Oleaceae family (e.g. Syringa vulgaris), their preparation and use | I.R.B. ISTITUTO DI RICERCHE BIOTECNOLOGICHE S.R.L. (IT) | 2010-05-18 | — | — | US | disclosed |
| US-20070015262-A1 | Extracts from Ajuga reptans cell lines, their preparation and use | I.R.B. ISTITUTO DI RICERCHE BIOTECNOLOGICHE S.R.L. (IT) | 2007-01-18 | — | — | US | disclosed |
| US-20070004011-A1 | Extracts obtained from cell line cultures from plants belonging to the Oleaceae family (e.g. Syringa vulgaris), their preparation and use | I.R.B. ISTITUTO DI RICERCHE BIOTECNOLOGICHE S.R.I. (IT) | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (15 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130237609-A1 | CELLULOSE DERIVATIVES FOR ENHANCING BIOAVAILABILITY OF FLAVONOIDS | KEAP1, NQO1, ABCG2 | IAPP 295/4885PTGS1 1696/4885MMP2 1679/4885 |
| US-20140294859-A1 | AQUEOUS FORMULATION OF ERYTHROPOIESIS STIMULATING PROTEIN STABILISED BY ANTIOXIDANTS FOR PARENTERAL ADMINISTRATION | EPOR, TTPA, ALB | IAPP 751/4885PTGS1 1753/4885MMP2 3641/4885 |
| US-20070015262-A1 | Extracts from Ajuga reptans cell lines, their preparation and use | TTPA, FABP4, ACOX3 | IAPP 2590/4885PTGS1 345/4885MMP2 510/4885 |
| US-11701400-B2 | Steviol glycoside compositions with reduced surface tension | STT3A, SIGLEC7, STT3B | IAPP 3432/4885PTGS1 675/4885MMP2 2237/4885 |
| US-20180078535-A1 | THERAPEUTIC COMPOSITIONS CONTAINING HARMINE AND ISOVANILLIN COMPONENTS, AND METHODS OF USE THEREOF | INMT, HNMT, COMT | IAPP 1777/4885PTGS1 3044/4885MMP2 1432/4885 |
| US-20070004011-A1 | Extracts obtained from cell line cultures from plants belonging to the Oleaceae family (e.g. Syringa vulgaris), their preparation and use | CAT, CUTA, VAPA | IAPP 2810/4885PTGS1 807/4885MMP2 87/4885 |
| US-20230126688-A1 | Aqueous Formulation of Erythropoiesis Stimulating Protein Stabilised by Antioxidants for Parenteral Administration | EPOR, TTPA, ALB | IAPP 751/4885PTGS1 1753/4885MMP2 3641/4885 |
| US-20230130823-A1 | PROCESS FOR THE PRODUCTION OF ANTITUMOUR PHARMACEUTICAL COMPOSITIONS USING PUSH-PULL BUTADIENES, COMPOUNDS AND USES THEREOF | BAD, BAX, PDCD4 | IAPP 3164/4885PTGS1 2332/4885MMP2 1190/4885 |
| US-20130157986-A1 | NOVEL METHYLENEDIOXY PHENOLIC COMPOUNDS AND THEIR USE TO TREAT DISEASE | REN, PCSK9, COMT | IAPP 350/4885PTGS1 131/4885MMP2 111/4885 |
| US-11717549-B2 | Steviol glycoside solubility enhancers | SI, TAS2R7, TAS2R31 | IAPP 214/4885PTGS1 1023/4885MMP2 4044/4885 |
| US-20110123646-A1 | Extracts Obtained from Cell Line Cultures from Plants Belonging to the Oleaceae Family (e.g. Syringa Vulgaris), Their Preparation and Use | CAT, CUTA, VAPA | IAPP 2810/4885PTGS1 807/4885MMP2 87/4885 |
| US-20150011494-A1 | THERAPEUTIC CURCUMIN DERIVATIVES | FABP2, GLS2, FABP1 | IAPP 336/4885PTGS1 153/4885MMP2 399/4885 |
| US-11654120-B2 | Composition for treating skin conditions | CUTA, DSG1, ERCC1 | IAPP 3329/4885PTGS1 1310/4885MMP2 1116/4885 |
| US-20230364069-A1 | METHOD FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS THROUGH CO-ADMINISTRATION OF CURCUMIN DERIVATIVE AND TGF-B RECEPTOR INHIBITOR | TGFBR2, TGFBR1, TGFB1 | IAPP 190/4885PTGS1 861/4885MMP2 1215/4885 |
| US-20230364171-A1 | SENSORY MODIFIER COMPOUNDS | TAS2R4, TAS2R50, TAS2R20 | IAPP 242/4885PTGS1 2335/4885MMP2 4861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.