Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 known ✓ | Q99720 | 3/20 | 0.56 |
| ▸ | BCHE known ✓ | P06276 | 1/20 | 0.48 |
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 4/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1330333 | 1.00 | SIGMAR1 (0.56) | SIGMAR1TLR2BCHEEPHX2CSNK1E | |
| Hydrochloric Acid SCHEMBL11272545 | 1.00 | SIGMAR1 (0.56) | SIGMAR1TLR2BCHEEPHX2CSNK1E | |
| Hydrochloric Acid SCHEMBL5925639 | 1.00 | SIGMAR1 (0.56) | SIGMAR1TLR2BCHEEPHX2CSNK1E | |
| SCHEMBL667265 | 0.98 | SIGMAR1 (0.58) | SIGMAR1TLR2BCHEEPHX2CSNK1E | |
| SCHEMBL666714 | 0.98 | SIGMAR1 (0.58) | SIGMAR1TLR2BCHEEPHX2CSNK1E | |
| SCHEMBL19868618 | 0.98 | SIGMAR1 (0.58) | SIGMAR1TLR2BCHEEPHX2CSNK1E | |
| SCHEMBL27919164 | 0.98 | SIGMAR1 (0.58) | SIGMAR1TLR2BCHEEPHX2CSNK1E | |
| Bromide SCHEMBL1330662 | 0.97 | SIGMAR1 (0.56) | SIGMAR1TLR2BCHEEPHX2CSNK1E | |
| Bromide SCHEMBL1330640 | 0.97 | SIGMAR1 (0.56) | SIGMAR1TLR2BCHEEPHX2CSNK1E | |
| SCHEMBL2794487 | 0.97 | SIGMAR1 (0.59) | SIGMAR1TLR2BCHEEPHX2CSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962662-B2 | Antimicrobial compositions and methods of use thereof | BYOCOAT ENTERPRISES, INC. (US) | 2015-02-24 | — | — | US | disclosed |
| US-8586115-B2 | Antimicrobial solutions and process related thereto | BYOCOAT ENTERPRISES, INC. (US) | 2013-11-19 | — | — | US | disclosed |
| US-20130137732-A1 | ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE THEREOF | BYOCOAT ENTERPRISES, INC. (US) | 2013-05-30 | — | — | US | disclosed |
| WO-2013074526-A2 | ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE THEREOF | BYOCOAT ENTERPRISES, INC. (US) | 2013-05-23 | — | — | WO | disclosed |
| US-20120264758-A1 | ANTIMICROBIAL SOLUTIONS AND PROCESS RELATED THERETO | BYOCOAT ENTERPRISES, INC. (US) | 2012-10-18 | — | — | US | disclosed |
| CN-101316516-B | Antimicrobial solutions and methods relating thereto | BYOCOAT ENTPR INC | 2012-05-30 | — | — | CN | disclosed |
| US-20110281002-A1 | ANTIMICROBIAL SOLUTIONS AND PROCESS RELATED THERETO | BYOCOAT ENTERPRISES, INC. (PR) | 2011-11-17 | — | — | US | disclosed |
| CN-102083313-A | Compositions and methods for reducing or preventing microorganism growth or survival in aqueous environments | BYOCOAT ENTPR INC | 2011-06-01 | — | — | CN | disclosed |
| US-20090192165-A1 | ANTIMICROBIAL SOLUTIONS AND PROCESS RELATED THERETO | BYOCOAT ENTERPRISES, INC. (PR) | 2009-07-30 | — | — | US | disclosed |
| CN-101316516-A | Antimicrobial solutions and methods relating thereto | BYOCOAT ENTPR INC (US) | 2008-12-03 | — | — | CN | disclosed |
| EP-1931209-A1 | ANTIMICROBIAL SOLUTIONS AND PROCESS RELATED THERETO | Byocoat Enterprises, Inc. (US) | 2008-06-18 | — | — | EP | disclosed |
| WO-2008008362-A2 | COMPOSITIONS AND METHODS FOR REDUCING OR PREVENTING MICROORGANISM GROWTH OR SURVIVAL IN AQUEOUS ENVIRONMENTS | BYOCOAT ENTERPRISES, INC. (US) | 2008-01-17 | — | — | WO | disclosed |
| WO-2007030104-A1 | ANTIMICROBIAL SOLUTIONS AND PROCESS RELATED THERETO | BYOCOAT ENTERPRISES, INC. (US) | 2007-03-15 | — | — | WO | disclosed |
| US-20060110506-A1 | Antimicrobial solutions and process related thereto | BYOCOAT ENTERPRISES, INC. | 2006-05-25 | — | — | US | disclosed |
| US-20050271781-A1 | Antimicrobial solutions and process related thereto | BYOCOAT ENTERPRISES, INC. | 2005-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137732-A1 | ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE THEREOF | KARS1, AAAS, AARS1 | SIGMAR1 793/4885BCHE 906/4885GAA 350/4885 |
| US-20110281002-A1 | ANTIMICROBIAL SOLUTIONS AND PROCESS RELATED THERETO | DAO, AGPS, TH | SIGMAR1 509/4885BCHE 256/4885GAA 642/4885 |
| US-20090192165-A1 | ANTIMICROBIAL SOLUTIONS AND PROCESS RELATED THERETO | DAO, AGPS, DDC | SIGMAR1 955/4885BCHE 470/4885GAA 711/4885 |
| US-20120264758-A1 | ANTIMICROBIAL SOLUTIONS AND PROCESS RELATED THERETO | DAO, AGPS, DDC | SIGMAR1 955/4885BCHE 470/4885GAA 711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.