Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.37 |
| ▸ | TOP1 known ✓ | P11387 | 1/20 | 0.37 |
| ▸ | CYP19A1 known ✓ | P11511 | 1/20 | 0.37 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.37 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.37 |
| ▸ | FLT3 known ✓ | P36888 | 1/20 | 0.37 |
| ▸ | PPARG known ✓ | P37231 | 1/20 | 0.37 |
| ▸ | KCNH2 known ✓ | Q12809 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 3/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | TERT | O14746 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | FABP4 | P15090 | 2/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL142026 | 1.00 | FAAH (0.37) | FAAHTRPV1TERTMAPTBLM | |
| SCHEMBL141304 | 0.98 | FAAH (0.38) | FAAHTRPV1TERTMAPTBLM | |
| SCHEMBL141306 | 0.98 | FAAH (0.38) | FAAHTRPV1TERTMAPTBLM | |
| SCHEMBL31085540 | 0.88 | MEN1 (0.40) | MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL29396916 | 0.85 | MGLL (0.50) | TRPV1MAPT | |
| Hydrochloric Acid SCHEMBL1047267 | 0.85 | MGLL (0.50) | TRPV1MAPT | |
| Hydrochloric Acid SCHEMBL28736736 | 0.84 | MGLL (0.49) | TRPV1MAPT | |
| SCHEMBL441411 | 0.83 | MGLL (0.51) | TRPV1MAPT | |
| SCHEMBL28968652 | 0.83 | MGLL (0.51) | TRPV1MAPT | |
| SCHEMBL30180550 | 0.83 | MGLL (0.51) | TRPV1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2807278-B1 | FAT-LIQUORING | STAHL INT B V (NL) | 2021-12-01 | — | — | EP | disclosed |
| EP-2633088-B1 | NON METAL TANNING | STAHL INT B V (NL) | 2018-09-12 | — | — | EP | disclosed |
| EP-2633086-B1 | NON-METAL TANNING PROCESS | STAHL INT B V (NL) | 2017-08-16 | — | — | EP | disclosed |
| EP-2633089-B1 | NON METAL TANNING | STAHL INT B V (NL) | 2017-03-15 | — | — | EP | disclosed |
| EP-2638181-B1 | NON METAL TANNING | STAHL INT B V (NL) | 2017-02-22 | — | — | EP | disclosed |
| US-9447477-B2 | Fat-liquoring | STAHL INTERNATIONAL B.V. (NL) | 2016-09-20 | — | — | US | disclosed |
| US-20140366280-A1 | FAT-LIQUORING | STAHL INTERNATIONAL B.V. (NL) | 2014-12-18 | — | — | US | disclosed |
| EP-2807278-A1 | FAT-LIQUORING | Stahl International B.V. (NL) | 2014-12-03 | — | — | EP | disclosed |
| EP-2638179-B1 | NON METAL TANNING | STAHL INT BV (NL) | 2014-11-26 | — | — | EP | disclosed |
| EP-2638180-B1 | NON METAL TANNING | STAHL INT BV (NL) | 2014-11-26 | — | — | EP | disclosed |
| WO-2012062413-A1 | NON METAL TANNING | CLARIANT INTERNATIONAL LTD (CH) | 2012-05-18 | — | — | WO | disclosed |
| WO-2012062412-A1 | NON METAL TANNING | CLARIANT INTERNATIONAL LTD (CH) | 2012-05-18 | — | — | WO | disclosed |
| WO-2012062411-A1 | NON METAL TANNING | CLARIANT INTERNATIONAL LTD (CH) | 2012-05-18 | — | — | WO | disclosed |
| WO-2012055480-A1 | NON METAL TANNING | CLARIANT INTERNATIONAL LTD (CH) | 2012-05-03 | — | — | WO | disclosed |
| WO-2012055481-A1 | NON METAL TANNING | CLARIANT INTERNATIONAL LTD (CH) | 2012-05-03 | — | — | WO | disclosed |
| WO-2012055482-A1 | NON-METAL TANNING PROCESS | CLARIANT INTERNATIONAL LTD (CH) | 2012-05-03 | — | — | WO | disclosed |
| WO-2012055483-A1 | NON-METAL TANNING PROCESS | CLARIANT INTERNATIONAL LTD (CH) | 2012-05-03 | — | — | WO | disclosed |
| EP-2430197-A1 | TANNING PROCESS AND TANNING COMPOSITION | Clariant Finance (BVI) Limited (VG) | 2012-03-21 | — | — | EP | disclosed |
| US-20120058357-A1 | Tanning Process and Tanning Composition | CLARIANT FINANCE (BVI) LIMITED (VG) | 2012-03-08 | — | — | US | disclosed |
| WO-2010130311-A1 | TANNING PROCESS AND TANNING COMPOSITION | CLARIANT INTERNATIONAL LTD (CH) | 2010-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140366280-A1 | FAT-LIQUORING | FABP4, PLOD3, AGXT | CHRM1 3633/4885TOP1 3811/4885CYP19A1 328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.