SCHEMBL16050638

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29700748	1.00	GPR84 (0.69)	GPR84PTGS2CYP3A4ALDH1A1ALOX5
	SCHEMBL17678365	0.85	GPR84 (0.53)	GPR84PTGS2CYP3A4ALDH1A1ALOX5
	SCHEMBL29555599	0.84	ALDH1A1 (0.56)	GPR84PTGS2CYP3A4ALDH1A1ALOX5
	SCHEMBL16050413	0.84	ALDH1A1 (0.56)	GPR84PTGS2CYP3A4ALDH1A1ALOX5
	SCHEMBL19166809	0.84	GPR84 (0.51)	GPR84PTGS2CYP3A4ALDH1A1ALOX5
	SCHEMBL17678366	0.84	GPR84 (0.51)	GPR84PTGS2CYP3A4ALDH1A1ALOX5
	SCHEMBL17672982	0.84	GPR84 (0.67)	GPR84PTGS2CYP3A4ALDH1A1ALOX5
	SCHEMBL1160403	0.83	PTGS2 (0.63)	GPR84PTGS2CYP3A4ALDH1A1ALOX5
	SCHEMBL25346230	0.83	GPR84 (0.50)	GPR84PTGS2CYP3A4ALDH1A1ALOX5
	SCHEMBL19166230	0.83	PTGS2 (0.50)	GPR84PTGS2CYP3A4ALDH1A1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.