Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.42 |
| ▸ | PDE4B known ✓ | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4D known ✓ | Q08499 | 1/20 | 0.41 |
| ▸ | PDE7A known ✓ | Q13946 | 1/20 | 0.41 |
| ▸ | PDE7B known ✓ | Q9NP56 | 1/20 | 0.41 |
| ▸ | CYP19A1 known ✓ | P11511 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.43 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.43 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.43 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.42 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30611013 | 1.00 | NPC1 (0.56) | NPC1RAB9AATMTXNRD1TXNRD3 | |
| SCHEMBL10439894 | 0.99 | NPC1 (0.58) | NPC1RAB9AATMTXNRD1TXNRD3 | |
| Hydrochloric Acid SCHEMBL11217818 | 0.99 | NPC1 (0.58) | NPC1RAB9AATMTXNRD1TXNRD3 | |
| SCHEMBL29595963 | 0.99 | NPC1 (0.58) | NPC1RAB9AATMTXNRD1TXNRD3 | |
| Bromide SCHEMBL28656768 | 0.96 | NPC1 (0.55) | NPC1RAB9AATMTXNRD1TXNRD3 | |
| Hydrochloric Acid SCHEMBL599994 | 0.91 | NPC1 (0.65) | NPC1RAB9AATMTXNRD1TXNRD3 | |
| Hydrochloric Acid SCHEMBL30343291 | 0.91 | NPC1 (0.65) | NPC1RAB9AATMTXNRD1TXNRD3 | |
| SCHEMBL11694301 | 0.90 | NPC1 (0.62) | NPC1RAB9AATMTXNRD1TXNRD3 | |
| Bromide SCHEMBL5144105 | 0.88 | NPC1 (0.61) | NPC1RAB9AATMTXNRD1TXNRD3 | |
| Hydrochloric Acid SCHEMBL8068701 | 0.86 | NPC1 (0.67) | NPC1RAB9AATMTXNRD1TXNRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946660-A | Freezing history indicator and application thereof | 吉林大学 | 2024-04-30 | — | — | CN | claimed |
| CN-117946660-A | Freezing history indicator and application thereof | 吉林大学 | 2024-04-30 | — | — | CN | disclosed |
| EP-4321235-A1 | CARBON DIOXIDE CAPTURE SYSTEM AND CARBON DIOXIDE CAPTURE METHOD | KABUSHIKI KAISHA TOSHIBA (JP) | 2024-02-14 | — | — | EP | disclosed |
| US-20240042380-A1 | CARBON DIOXIDE CAPTURE SYSTEM AND CARBON DIOXIDE CAPTURE METHOD | KABUSHIKI KAISHA TOSHIBA (JP) | 2024-02-08 | — | — | US | disclosed |
| EP-2848667-B1 | Electrochromic single and two-core viologens and optical articles containing them | ESSILOR INT (FR) | 2019-04-10 | — | — | EP | disclosed |
| US-9823534-B2 | Electrochromic single and two-core viologens and optical articles containing them | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2017-11-21 | — | — | US | disclosed |
| US-20160231635-A1 | ELECTROCHROMIC SINGLE AND TWO-CORE VIOLOGENS AND OPTICAL ARTICLES CONTAINING THEM | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2016-08-11 | — | — | US | disclosed |
| WO-2015040033-A2 | ELECTROCHROMIC SINGLE AND TWO-CORE VIOLOGENS AND OPTICAL ARTICLES CONTAINING THEM | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2015-03-26 | — | — | WO | disclosed |
| EP-2848667-A1 | Electrochromic single and two-core viologens and optical articles containing them | ESSILOR INTERNATIONAL (Compagnie Générale d'Optique) (FR) | 2015-03-18 | — | — | EP | disclosed |
| US-8279513-B2 | Electrochromic materials and electrochromic devices using the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2012-10-02 | — | — | US | disclosed |
| US-20110184181-A1 | ELECTROCHROMIC MATERIALS AND ELECTROCHROMIC DEVICES USING THE SAME | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2011-07-28 | — | — | US | disclosed |
| US-7944597-B2 | Electrochromic materials and electrochromic devices using the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2011-05-17 | — | — | US | disclosed |
| US-20100053724-A1 | ELECTROCHROMIC MATERIALS AND ELECTROCHROMIC DEVICES USING THE SAME | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2010-03-04 | — | — | US | disclosed |
| US-20090259042-A1 | ELECTROCHROMIC COMPOUNDS | NTERA LIMITED (IE) | 2009-10-15 | — | — | US | disclosed |
| US-7567371-B2 | Electrochromic compounds | NTERA LIMITED (IE) | 2009-07-28 | — | — | US | disclosed |
| US-20060110638-A1 | Electrochromic compounds | NTERA LIMITED (IE) | 2006-05-25 | — | — | US | disclosed |
| EP-1594938-A1 | ELECTROCHROMIC COMPOUNDS | Ntera Limited (IE) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004067673-A1 | ELECTROCHROMIC COMPOUNDS | NTERA LIMITED (IE) | 2004-08-12 | — | — | WO | disclosed |
| EP-1443091-A1 | Electrochromic compounds | Ntera Limited (IE) | 2004-08-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090259042-A1 | ELECTROCHROMIC COMPOUNDS | ETV6, HCN2, EED | GAA 3729/4885PDE4B 3549/4885PDE4D 4137/4885 |
| US-20060110638-A1 | Electrochromic compounds | ETV6, HCN2, EED | GAA 3729/4885PDE4B 3549/4885PDE4D 4137/4885 |
| US-20110184181-A1 | ELECTROCHROMIC MATERIALS AND ELECTROCHROMIC DEVICES USING THE SAME | ESYT2, EED, EYA2 | GAA 4109/4885PDE4B 2431/4885PDE4D 2134/4885 |
| US-20160231635-A1 | ELECTROCHROMIC SINGLE AND TWO-CORE VIOLOGENS AND OPTICAL ARTICLES CONTAINING THEM | EYA2, CRY2, EYA3 | GAA 4558/4885PDE4B 4514/4885PDE4D 4223/4885 |
| US-20100053724-A1 | ELECTROCHROMIC MATERIALS AND ELECTROCHROMIC DEVICES USING THE SAME | ESYT2, EED, EYA2 | GAA 4109/4885PDE4B 2431/4885PDE4D 2134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.