Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18457812 | 0.92 | PLG (0.38) | ALDH1A1PKMTHRATHRBZDHHC20 | |
| SCHEMBL19479961 | 0.86 | ZDHHC20 (0.43) | ALDH1A1PKMTHRATHRBZDHHC20 | |
| SCHEMBL19622368 | 0.82 | THRA (0.30) | THRATHRB | |
| SCHEMBL21335859 | 0.80 | MAPT (0.33) | THRATHRB | |
| SCHEMBL14880 | 0.79 | — | — | |
| SCHEMBL2413777 | 0.78 | ALOX5 (0.46) | ALOX5 | |
| SCHEMBL3116394 | 0.78 | ALDH1A1 (0.36) | ALDH1A1ZDHHC20ZDHHC2TSHRPSMB5 | |
| SCHEMBL21350939 | 0.77 | MAPT (0.32) | — | |
| Ammonia Solution, Strong SCHEMBL28481040 | 0.77 | ZDHHC20 (0.43) | ALDH1A1ZDHHC20ZDHHC2TSHRPSMB5 | |
| SCHEMBL17472047 | 0.75 | ALDH1A1 (0.41) | ALDH1A1PKMALOX5MLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11857650-B2 | Dental composition comprising a dental filler containing a structural filler and silanated glass flakes | DENTSPLY SIRONA INC. (US) | 2024-01-02 | — | — | US | disclosed |
| US-11857650-B2 | Dental composition comprising a dental filler containing a structural filler and silanated glass flakes | DENTSPLY SIRONA INC. (US) | 2024-01-02 | — | — | US | disclosed |
| US-20220202658-A1 | DENTAL COMPOSITION | DENTSPLY SIRONA INC. (US) | 2022-06-30 | — | — | US | disclosed |
| US-20220031576-A1 | ADDITIVE MANUFACTURING PROCESS | DENTSPLY SIRONA INC. (US) | 2022-02-03 | — | — | US | disclosed |
| US-20220000721-A1 | BIFUNCTIONAL AND POLYFUNCTIONAL COINITIATORS IN DENTAL COMPOSITIONS | DENTSPLY SIRONA INC. (US) | 2022-01-06 | — | — | US | disclosed |
| US-11166883-B2 | Dental composition | DENTSPLY SIRONA INC. (US) | 2021-11-09 | — | — | US | disclosed |
| US-11141357-B2 | Dental adhesive | DENTSPLY SIRONA INC. (US) | 2021-10-12 | — | — | US | disclosed |
| US-11116702-B2 | Dental composition | DENTSPLY SIRONA INC. (US) | 2021-09-14 | — | — | US | disclosed |
| US-11110039-B2 | Macromonomer based light-curable dental impression material | DENTSPLY SIRONA INC. (US) | 2021-09-07 | — | — | US | disclosed |
| US-20210137795-A1 | DENTAL ADHESIVE | DENTSPLY SIRONA INC. (US) | 2021-05-13 | — | — | US | disclosed |
| US-20190231648-A1 | DENTAL COMPOSITION COMPRISING A DENTAL FILLER CONTAINING A STRUCTURAL FILLER AND SILANATED GLASS FLAKES | DENTSPLY SIRONA INC. (US) | 2019-08-01 | — | — | US | disclosed |
| US-10272017-B2 | Aqueous dental glass ionomer composition | DENTSPLY SIRONA INC. (US) | 2019-04-30 | — | — | US | disclosed |
| US-20190117522-A1 | DENTAL COMPOSITION | DENTSPLY SIRONA INC. (US) | 2019-04-25 | — | — | US | disclosed |
| US-20180221249-A1 | DENTAL ADHESIVE | DENTSPLY SIRONA INC. (US) | 2018-08-09 | — | — | US | disclosed |
| US-20180221249-A1 | DENTAL ADHESIVE | DENTSPLY SIRONA INC. (US) | 2018-08-09 | — | — | US | disclosed |
| US-20180214351-A1 | DENTAL ADHESIVE | DENTSPLY SIRONA INC. (US) | 2018-08-02 | — | — | US | disclosed |
| US-20170296442-A1 | AQUEOUS DENTAL GLASS IONOMER COMPOSITION | DENTSPLY SIRONA INC. (US) | 2017-10-19 | — | — | US | disclosed |
| US-20170296441-A1 | AQUEOUS DENTAL GLASS IONOMER COMPOSITION | DENTSPLY SIRONA INC. (US) | 2017-10-19 | — | — | US | disclosed |
| US-20170296441-A1 | AQUEOUS DENTAL GLASS IONOMER COMPOSITION | DENTSPLY SIRONA INC. (US) | 2017-10-19 | — | — | US | disclosed |
| US-20170296442-A1 | AQUEOUS DENTAL GLASS IONOMER COMPOSITION | DENTSPLY SIRONA INC. (US) | 2017-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (16 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190117522-A1 | DENTAL COMPOSITION | MSR1, TAS2R3, TAS2R39 | ALDH1A1 3077/4885PKM 2427/4885THRA 1133/4885 |
| US-20170296441-A1 | AQUEOUS DENTAL GLASS IONOMER COMPOSITION | GLUL, GDA, PHAX | ALDH1A1 1935/4885PKM 1474/4885THRA 2150/4885 |
| US-11141357-B2 | Dental adhesive | CDH1, ITGA5, ICAM1 | ALDH1A1 404/4885PKM 4810/4885THRA 2933/4885 |
| US-20180221249-A1 | DENTAL ADHESIVE | CDH1, F12, ITGA8 | ALDH1A1 119/4885PKM 1978/4885THRA 1095/4885 |
| US-20220202658-A1 | DENTAL COMPOSITION | CAD, PHOSPHO1, PLA2G2C | ALDH1A1 2211/4885PKM 1519/4885THRA 3714/4885 |
| US-20220000721-A1 | BIFUNCTIONAL AND POLYFUNCTIONAL COINITIATORS IN DENTAL COMPOSITIONS | DUOX2, DUOX1, QSOX1 | ALDH1A1 541/4885PKM 4003/4885THRA 3004/4885 |
| US-20170296442-A1 | AQUEOUS DENTAL GLASS IONOMER COMPOSITION | COG1, GDA, COG2 | ALDH1A1 2568/4885PKM 3522/4885THRA 2223/4885 |
| US-11110039-B2 | Macromonomer based light-curable dental impression material | EPM2A, LMNB1, LMNB2 | ALDH1A1 1272/4885PKM 3423/4885THRA 2043/4885 |
| US-20210137795-A1 | DENTAL ADHESIVE | CDH1, ITGA5, ICAM1 | ALDH1A1 404/4885PKM 4810/4885THRA 2933/4885 |
| US-11857650-B2 | Dental composition comprising a dental filler containing a structural filler and silanated glass flakes | DHX35, DHX30, FLNA | ALDH1A1 2605/4885PKM 4383/4885THRA 3408/4885 |
| US-11116702-B2 | Dental composition | MTR, CAD, PAM | ALDH1A1 1171/4885PKM 2006/4885THRA 1381/4885 |
| US-20190231648-A1 | DENTAL COMPOSITION COMPRISING A DENTAL FILLER CONTAINING A STRUCTURAL FILLER AND SILANATED GLASS FLAKES | DHX35, DHX30, FLNA | ALDH1A1 2605/4885PKM 4383/4885THRA 3408/4885 |
| US-11166883-B2 | Dental composition | MSR1, TAS2R3, TAS2R39 | ALDH1A1 3077/4885PKM 2427/4885THRA 1133/4885 |
| US-20180214351-A1 | DENTAL ADHESIVE | CDH1, ITGA5, ICAM1 | ALDH1A1 404/4885PKM 4810/4885THRA 2933/4885 |
| US-10272017-B2 | Aqueous dental glass ionomer composition | COG1, GDA, COG2 | ALDH1A1 2568/4885PKM 3522/4885THRA 2223/4885 |
| US-20220031576-A1 | ADDITIVE MANUFACTURING PROCESS | FLNA, FLNB, SAMM50 | ALDH1A1 1755/4885PKM 2486/4885THRA 1104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.