Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.67 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.57 |
| ▸ | FEN1 | P39748 | 1/20 | 0.57 |
| ▸ | CES2 | O00748 | 2/20 | 0.56 |
| ▸ | CES1 | P23141 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11778904 | 0.91 | MAPT (0.63) | GSK3BERCC5FEN1CES2CES1 | |
| SCHEMBL11110229 | 0.88 | MMP1 (0.61) | GSK3BERCC5FEN1CES2CES1 | |
| SCHEMBL30694356 | 0.87 | KDM4E (0.50) | GSK3BCES1L3MBTL1MAPTALOX15 | |
| SCHEMBL16552727 | 0.82 | GSK3B (0.70) | GSK3BERCC5FEN1CES2CES1 | |
| SCHEMBL600674 | 0.82 | ERCC5 (0.72) | GSK3BERCC5FEN1CES2CES1 | |
| SCHEMBL8750790 | 0.81 | L3MBTL1 (0.65) | GSK3BERCC5FEN1CES2CES1 | |
| SCHEMBL26106172 | 0.80 | NR4A2 (0.71) | MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL953871 | 0.80 | GSK3B (1.00) | GSK3BERCC5FEN1CES2CES1 | |
| SCHEMBL14226875 | 0.80 | ALDH1A1 (0.45) | GSK3BERCC5FEN1CES1L3MBTL1 | |
| SCHEMBL5254933 | 0.80 | GSK3B (0.67) | GSK3BERCC5FEN1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 280 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114751870-B | 2- (isoxazole-5-yl) phenyl-3, 4-dihydroxybenzoate and derivative thereof, and synthetic method and application thereof | 贵州医科大学 | 2023-10-20 | — | — | CN | claimed |
| CN-116515782-A | Amine dehydrogenase mutant and application thereof in chiral amine alcohol compound synthesis | 中国科学院天津工业生物技术研究所 | 2023-08-01 | — | — | CN | claimed |
| CN-114146071-B | Application of paeonol and its derivatives in preventing and treating leukoplakia syndrome | 西北农林科技大学深圳研究院 | 2023-02-28 | — | — | CN | claimed |
| CN-114751870-A | 2- (isoxazole-5-yl) phenyl-3, 4-dihydroxy benzoate and derivative thereof, and synthesis method and application thereof | 贵州医科大学 | 2022-07-15 | — | — | CN | claimed |
| CN-114146071-A | Application of paeonol and its derivatives in preventing and treating leukoplakia syndrome | 西北农林科技大学深圳研究院 | 2022-03-08 | — | — | CN | claimed |
| CN-104560745-B | A kind of Pichia yeast Pichia sp.SIT2014 and its cultural method and application | 上海应用技术学院 | 2017-12-01 | — | — | CN | claimed |
| US-9422583-B2 | Stereospecific carbonyl reductases | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-08-23 | — | — | US | claimed |
| US-20150167032-A1 | STEREOSPECIFIC CARBONYL REDUCTASES | JIANGNAN UNIVERSITY (CN) | 2015-06-18 | — | — | US | claimed |
| CN-104560745-A | Pichia sp.SIT2014 and culture method and application thereof | SHANGHAI INST TECHNOLOGY | 2015-04-29 | — | — | CN | claimed |
| CN-102102111-B | Method for synthesizing optically-active aryl vicinal diol under catalysis of plant cells | UNIV JIANGNAN | 2013-06-12 | — | — | CN | claimed |
| US-20120270285-A1 | STEREOSPECIFIC CARBONYL REDUCTASES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2012-10-25 | — | — | US | claimed |
| CN-102482649-A | Stereospecific carbonyl reductases | UNIV RUTGERS | 2012-05-30 | — | — | CN | claimed |
| CN-102206683-A | Synthesis method of optically active aryl vicinal diol under catalysis of whole yeast cells | UNIV JIANGNAN | 2011-10-05 | — | — | CN | claimed |
| CN-102102111-A | Method for synthesizing optically-active aryl vicinal diol under catalysis of plant cells | UNIV JIANGNAN | 2011-06-22 | — | — | CN | claimed |
| WO-2010151593-A1 | STEROSPECIFIC CARBONYL REDUCTASES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2010-12-29 | — | — | WO | claimed |
| CN-101580445-A | Method for microwave synthesis of alpha-hydroxyacetophenone series compounds | UNIV JIANGNAN (CN) | 2009-11-18 | — | — | CN | claimed |
| US-4343937-A | ANTIBIOTICS, BACTERICIDES | MERCK & CO., INC. (US) | 1982-08-10 | — | — | US | claimed |
| US-4297488-A | 7-α-Methoxy cephalosporins | MERCK & CO., INC. (US) | 1981-10-27 | — | — | US | claimed |
| US-4067866-A | Process for preparing cephalosporins and certain novel 2β-thiohydrazo-azetidinones as intermediates | SOCIETA' FARMACEUTICI ITALIA (IT) | 1978-01-10 | — | — | US | claimed |
| CN-120022203-A | Triazole derivatives of kojic acid with tyrosinase inhibitory activity, alpha-glucosidase inhibitory activity and antioxidant activity | 邵阳学院 | 2025-05-23 | — | — | CN | disclosed |
| US-12162890-B2 | Heteroaromatic NMDA receptor modulators and uses thereof | NOVARTIS AG (CH) | 2024-12-10 | — | — | US | disclosed |
| CN-118638089-B | Preparation method for synthesizing flavonoid compound based on carbon dioxide | 湖南工程学院 | 2024-11-12 | — | — | CN | disclosed |
| CN-118666845-A | Method for preparing indole [2,3-a ] carbazole derivative by using indole as raw material | 重庆医科大学 | 2024-09-20 | — | — | CN | disclosed |
| CN-118638089-A | Preparation method for synthesizing flavonoid compound based on carbon dioxide | 湖南工程学院 | 2024-09-13 | — | — | CN | disclosed |
| CN-116283722-B | Preparation method of 2- (2' -aminophenyl) carbazole compound under acidic condition | 重庆医科大学 | 2024-06-11 | — | — | CN | disclosed |
| CN-114805224-B | Ligustrazine chalcone derivative and preparation method and application thereof | 山东大学 | 2024-03-22 | — | — | CN | disclosed |
| CN-114751870-B | 2- (isoxazole-5-yl) phenyl-3, 4-dihydroxybenzoate and derivative thereof, and synthetic method and application thereof | 贵州医科大学 | 2023-10-20 | — | — | CN | disclosed |
| CN-116715671-A | Application of alpha-chromene spiropiperidine compound in preparation of 5-hydroxytryptamine 2C receptor agonist | 苏州大学 | 2023-09-08 | — | — | CN | disclosed |
| CN-116515782-A | Amine dehydrogenase mutant and application thereof in chiral amine alcohol compound synthesis | 中国科学院天津工业生物技术研究所 | 2023-08-01 | — | — | CN | disclosed |
| CN-116283722-A | Preparation method of 2- (2' -aminophenyl) carbazole compound under acidic condition | 重庆医科大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-114146071-B | Application of paeonol and its derivatives in preventing and treating leukoplakia syndrome | 西北农林科技大学深圳研究院 | 2023-02-28 | — | — | CN | disclosed |
| US-20230023543-A1 | HETEROAROMATIC NMDA RECEPTOR MODULATORS AND USES THEREOF | NOVARTIS AG (CH) | 2023-01-26 | — | — | US | disclosed |
| US-20230023543-A1 | HETEROAROMATIC NMDA RECEPTOR MODULATORS AND USES THEREOF | NOVARTIS AG (CH) | 2023-01-26 | — | — | US | disclosed |
| CN-115068475-A | Application of alpha-chromene spiropiperidine compounds in preparation of 5-hydroxytryptamine 2C receptor agonists | 苏州大学 | 2022-09-20 | — | — | CN | disclosed |
| CN-115040497-A | Application of paeonol derivative in preventing and treating leukoplakia syndrome | 西北农林科技大学深圳研究院 | 2022-09-13 | — | — | CN | disclosed |
| CN-113135814-B | Method for synthesizing chiral 1, 2-diol compound | 温州大学 | 2022-08-02 | — | — | CN | disclosed |
| CN-114805224-A | Ligustrazine chalcone derivative and preparation method and application thereof | 山东大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-114751870-A | 2- (isoxazole-5-yl) phenyl-3, 4-dihydroxy benzoate and derivative thereof, and synthesis method and application thereof | 贵州医科大学 | 2022-07-15 | — | — | CN | disclosed |
| US-11274102-B2 | Compounds useful in HIV therapy | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2022-03-15 | — | — | US | disclosed |
| CN-114146071-A | Application of paeonol and its derivatives in preventing and treating leukoplakia syndrome | 西北农林科技大学深圳研究院 | 2022-03-08 | — | — | CN | disclosed |
| US-11236104-B2 | Heteroaromatic NMDA receptor modulators and uses thereof | CADENT THERAPEUTICS, INC. (US) | 2022-02-01 | — | — | US | disclosed |
| US-11236104-B2 | Heteroaromatic NMDA receptor modulators and uses thereof | CADENT THERAPEUTICS, INC. (US) | 2022-02-01 | — | — | US | disclosed |
| CN-108558813-B | Resveratrol derivative containing flavonoid as well as preparation method and application thereof | 合肥工业大学 | 2021-07-23 | — | — | CN | disclosed |
| CN-113135814-A | Method for synthesizing chiral 1, 2-diol compound | 温州大学 | 2021-07-20 | — | — | CN | disclosed |
| CN-109134481-B | Substituted pyrrole chromone compound or pharmaceutically acceptable salt thereof, and preparation method and application thereof | 中山大学 | 2021-05-14 | — | — | CN | disclosed |
| WO-2021081207-A1 | GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2021-04-29 | — | — | WO | disclosed |
| US-20210107916-A1 | HETEROAROMATIC NMDA RECEPTOR MODULATORS AND USES THEREOF | NOVARTIS AG (CH) | 2021-04-15 | — | — | US | disclosed |
| US-20210107916-A1 | HETEROAROMATIC NMDA RECEPTOR MODULATORS AND USES THEREOF | NOVARTIS AG (CH) | 2021-04-15 | — | — | US | disclosed |
| CN-107324975-B | Direct hydroxylation or amination method of photocatalytic benzene and derivatives thereof | 中国科学院理化技术研究所 | 2020-11-24 | — | — | CN | disclosed |
| EP-3059235-B1 | TETRAZOLINONE DERIVATIVES AND THEIR USE FOR CONTROLLING PESTS | SUMITOMO CHEMICAL CO (JP) | 2020-10-28 | — | — | EP | disclosed |
| EP-3059235-B1 | TETRAZOLINONE DERIVATIVES AND THEIR USE FOR CONTROLLING PESTS | SUMITOMO CHEMICAL CO (JP) | 2020-10-28 | — | — | EP | disclosed |
| US-20200325147-A1 | Compounds Useful in HIV Therapy | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-10-15 | — | — | US | disclosed |
| US-20200325147-A1 | Compounds Useful in HIV Therapy | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-10-15 | — | — | US | disclosed |
| EP-3386591-B1 | HETEROAROMATIC NMDA RECEPTOR MODULATORS AND USES THEREOF | CADENT THERAPEUTICS INC (US) | 2020-06-24 | — | — | EP | disclosed |
| EP-3386591-B1 | HETEROAROMATIC NMDA RECEPTOR MODULATORS AND USES THEREOF | CADENT THERAPEUTICS INC (US) | 2020-06-24 | — | — | EP | disclosed |
| US-10626122-B2 | Heteroaromatic NMDA receptor modulators and uses thereof | CADENT THERAPEUTICS, INC. (US) | 2020-04-21 | — | — | US | disclosed |
| US-10626122-B2 | Heteroaromatic NMDA receptor modulators and uses thereof | CADENT THERAPEUTICS, INC. (US) | 2020-04-21 | — | — | US | disclosed |
| CN-107759550-B | O-hydroxyacetophenone class compound α-H is functionalized simultaneously and the method for the hexa-atomic miscellaneous oxygen cycle compound of Cyclization benzo | 沅江华龙催化科技有限公司 | 2019-11-05 | — | — | CN | disclosed |
| CN-110015983-A | 1,2- dicarbapentaborane class compound and its synthetic method | 华东师范大学 | 2019-07-16 | — | — | CN | disclosed |
| CN-109134481-A | A kind of substituted azole chromogen ketone compounds or its pharmaceutically acceptable salt and its preparation method and application | 中山大学 | 2019-01-04 | — | — | CN | disclosed |
| US-20180362541-A1 | HETEROAROMATIC NMDA RECEPTOR MODULATORS AND USES THEREOF | NOVARTIS AG (CH) | 2018-12-20 | — | — | US | disclosed |
| EP-3386591-A1 | HETEROAROMATIC NMDA RECEPTOR MODULATORS AND USES THEREOF | Cadent Therapeutics, Inc. (US) | 2018-10-17 | — | — | EP | disclosed |
| US-10085450-B2 | Tetrazolinone compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-10-02 | — | — | US | disclosed |
| CN-108484511-A | A kind of ligustrazine chalcone compounds and its preparation method and application | 山东大学 | 2018-09-04 | — | — | CN | disclosed |
| CN-104560745-B | A kind of Pichia yeast Pichia sp.SIT2014 and its cultural method and application | 上海应用技术学院 | 2017-12-01 | — | — | CN | disclosed |
| CN-107324975-A | Direct hydroxylation or amination method of photocatalytic benzene and derivatives thereof | 中国科学院理化技术研究所 | 2017-11-07 | — | — | CN | disclosed |
| EP-2841433-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE | SUMITOMO CHEMICAL CO (JP) | 2017-06-21 | — | — | EP | disclosed |
| WO-2017100591-A1 | HETEROAROMATIC NMDA RECEPTOR MODULATORS AND USES THEREOF | LUC THERAPEUTICS (US) | 2017-06-15 | — | — | WO | disclosed |
| WO-2017100591-A1 | HETEROAROMATIC NMDA RECEPTOR MODULATORS AND USES THEREOF | LUC THERAPEUTICS (US) | 2017-06-15 | — | — | WO | disclosed |
| EP-3121176-A1 | 2,4-DIAMINOQUINAZOLINES FOR THE TREATMENT OF SPINAL MUSCULAR ATROPHY | Families of Spinal Muscular Atrophy (US) | 2017-01-25 | — | — | EP | disclosed |
| US-20160270399-A1 | TETRAZOLINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-09-22 | — | — | US | disclosed |
| US-20160270399-A1 | TETRAZOLINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-09-22 | — | — | US | disclosed |
| US-20160270399-A1 | TETRAZOLINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-09-22 | — | — | US | disclosed |
| EP-3059235-A1 | TETRAZOLINONE COMPOUND AND APPLICATION FOR SAME | Sumitomo Chemical Company, Ltd. (JP) | 2016-08-24 | — | — | EP | disclosed |
| EP-3059235-A1 | TETRAZOLINONE COMPOUND AND APPLICATION FOR SAME | Sumitomo Chemical Company, Ltd. (JP) | 2016-08-24 | — | — | EP | disclosed |
| US-9422583-B2 | Stereospecific carbonyl reductases | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-08-23 | — | — | US | disclosed |
| EP-1765810-B1 | 2,4-DIAMINOQUINAZOLINES FOR THE TREATMENT OF SPINAL MUSCULAR ATROPHY | FAMILIES OF SPINAL MUSCULAR ATROPHY (US) | 2016-08-17 | — | — | EP | disclosed |
| EP-2514748-B1 | 2,4-diaminoquinazolines for spinal muscular atrophy | FAMILIES OF SPINAL MUSCULAR ATROPHY (US) | 2016-08-10 | — | — | EP | disclosed |
| US-9380782-B2 | Tetrazolinone compounds and its use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-07-05 | — | — | US | disclosed |
| US-20160152577-A1 | 2,4-Diaminoquinazolines for Spinal Muscular Atrophy | FAMILIES OF SPINAL MUSCULAR ATROPHY (US) | 2016-06-02 | — | — | US | disclosed |
| CN-105636957-A | Tetrazolinone compound and application for same | SUMITOMO CHEMICAL CO | 2016-06-01 | — | — | CN | disclosed |
| EP-1716141-B1 | BENZOPYRAN DERIVATIVES, METHOD OF PRODUCTION AND USE THEREOF | Université de Liège (BE) | 2016-01-20 | — | — | EP | disclosed |
| CN-105061166-A | Synthetic method of alpha-hydroxyacetophenone compound | UNIV LISHUI | 2015-11-18 | — | — | CN | disclosed |
| EP-2344460-B1 | NOVEL IMIDAZOLIDINE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | AKASHI THERAPEUTICS INC (US) | 2015-08-12 | — | — | EP | disclosed |
| EP-2344460-B1 | NOVEL IMIDAZOLIDINE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | AKASHI THERAPEUTICS INC (US) | 2015-08-12 | — | — | EP | disclosed |
| CN-104817483-A | Bis carbonyl indole compound and synthesis method | UNIV EAST CHINA NORMAL | 2015-08-05 | — | — | CN | disclosed |
| US-9067897-B2 | 2,4-Diaminoquinazolines for spinal muscular atrophy | FAMILIES OF SPINAL MUSCULAR ATROPHY (US) | 2015-06-30 | — | — | US | disclosed |
| US-20150167032-A1 | STEREOSPECIFIC CARBONYL REDUCTASES | JIANGNAN UNIVERSITY (CN) | 2015-06-18 | — | — | US | disclosed |
| CN-104560745-A | Pichia sp.SIT2014 and culture method and application thereof | SHANGHAI INST TECHNOLOGY | 2015-04-29 | — | — | CN | disclosed |
| WO-2015056806-A1 | TETRAZOLINONE COMPOUND AND APPLICATION FOR SAME | 住友化学株式会社 | 2015-04-23 | — | — | WO | disclosed |
| US-9000108-B2 | Process for selectively polymerizing ethylene and catalyst therefor | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-04-07 | — | — | US | disclosed |
| EP-2841433-A1 | TETRAZOLINONE COMPOUNDS AND ITS USE | Sumitomo Chemical Company Limited (JP) | 2015-03-04 | — | — | EP | disclosed |
| US-20150031733-A1 | TETRAZOLINONE COMPOUNDS AND ITS USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-01-29 | — | — | US | disclosed |
| CN-104177241-A | Alkynyl diketone compound and synthetic method thereof | UNIV EAST CHINA NORMAL | 2014-12-03 | — | — | CN | disclosed |
| CN-102482649-B | Stereospecific carbonyl reductases | UNIV RUTGERS | 2014-09-03 | — | — | CN | disclosed |
| US-20140235867-A1 | METHOD FOR PRODUCING ALPHA-HYDROXY KETONE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-08-21 | — | — | US | disclosed |
| US-20140163186-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-06-12 | — | — | US | disclosed |
| WO-2013035650-A9 | METHOD FOR PRODUCING ALPHA - HYDROXY KETONE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-03-13 | — | — | WO | disclosed |
| US-8653073-B2 | Dihydroindolone compounds, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2014-02-18 | — | — | US | disclosed |
| US-8609794-B2 | Process for selectively polymerizing ethylene and catalyst therefor | DOW GLOBAL TECHNOLOGIES, LLC. (US) | 2013-12-17 | — | — | US | disclosed |
| US-20130331380-A1 | DIHYDROINDOLONE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2013-12-12 | — | — | US | disclosed |
| EP-2491062-B1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-12-11 | — | — | EP | disclosed |
| WO-2013162077-A1 | TETRAZOLINONE COMPOUNDS AND ITS USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-10-31 | — | — | WO | disclosed |
| US-20130281709-A1 | PROCESS FOR PRODUCING ALPHA-HYDROXYKETONE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-10-24 | — | — | US | disclosed |
| WO-2013157651-A1 | PROCESS FOR PRODUCING ALPHA-HYDROXYKETONE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-10-24 | — | — | WO | disclosed |
| US-8541412-B2 | Dihydroindolone compounds, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2013-09-24 | — | — | US | disclosed |
| CN-102102111-B | Method for synthesizing optically-active aryl vicinal diol under catalysis of plant cells | UNIV JIANGNAN | 2013-06-12 | — | — | CN | disclosed |
| WO-2013074965-A1 | AMINOALKYL PHENOL ETHER INHIBITORS OF INFLUENZA A VIRUS | MICROBIOTIX, INC. (US) | 2013-05-23 | — | — | WO | disclosed |
| WO-2013035650-A1 | METHOD FOR PRODUCING ALPHA - HYDROXY KETONE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-03-14 | — | — | WO | disclosed |
| US-8383608-B2 | Imidazolidine compounds as androgen receptor modulators | DART THERAPEUTICS LLC | 2013-02-26 | — | — | US | disclosed |
| US-8383608-B2 | Imidazolidine compounds as androgen receptor modulators | DART THERAPEUTICS LLC | 2013-02-26 | — | — | US | disclosed |
| US-8383608-B2 | Imidazolidine compounds as androgen receptor modulators | DART THERAPEUTICS LLC | 2013-02-26 | — | — | US | disclosed |
| WO-2013018626-A1 | METHOD FOR PRODUCING ALPHA-KETOALDEHYDE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-02-07 | — | — | WO | disclosed |
| EP-2281822-B1 | New dihydroindolone derivatives, method of preparing same and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2013-01-16 | — | — | EP | disclosed |
| US-20120270285-A1 | STEREOSPECIFIC CARBONYL REDUCTASES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2012-10-25 | — | — | US | disclosed |
| EP-2514748-A1 | 2,4-diaminoquinazolines for spinal muscular atrophy | Families of Spinal Muscular Atrophy (US) | 2012-10-24 | — | — | EP | disclosed |
| EP-2491062-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | Dow Global Technologies LLC (US) | 2012-08-29 | — | — | EP | disclosed |
| US-20120178718-A1 | NOVEL IMIDAZOLIDINE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | AKASHI THERAPEUTICS, INC. | 2012-07-12 | — | — | US | disclosed |
| US-20120178718-A1 | NOVEL IMIDAZOLIDINE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | AKASHI THERAPEUTICS, INC. | 2012-07-12 | — | — | US | disclosed |
| US-20120178718-A1 | NOVEL IMIDAZOLIDINE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | AKASHI THERAPEUTICS, INC. | 2012-07-12 | — | — | US | disclosed |
| CN-1688532-B | Compositions based on substituted 1, 3-diphenylprop-2-en-1-one derivatives, preparation and use thereof | GENFIT | 2012-07-11 | — | — | CN | disclosed |
| CN-102482649-A | Stereospecific carbonyl reductases | UNIV RUTGERS | 2012-05-30 | — | — | CN | disclosed |
| US-8133889-B2 | Dihydroindolone compounds, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2012-03-13 | — | — | US | disclosed |
| US-20120046287-A1 | Dihydroindolone compounds, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2012-02-23 | — | — | US | disclosed |
| WO-2011146291-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-11-24 | — | — | WO | disclosed |
| US-20110282018-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | DOW GLOBAL TECHNOLOGIES LLC | 2011-11-17 | — | — | US | disclosed |
| CN-102206683-A | Synthesis method of optically active aryl vicinal diol under catalysis of whole yeast cells | UNIV JIANGNAN | 2011-10-05 | — | — | CN | disclosed |
| EP-1951697-B1 | SUBSTITUTED 5-PHENYL-3,6-DIHYDRO-2-OXO-6H-[1,3,4]THIADIAZINES | MERCK PATENT GMBH (DE) | 2011-07-27 | — | — | EP | disclosed |
| EP-2344460-A1 | NOVEL IMIDAZOLIDINE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Galapagos N.V. (BE) | 2011-07-20 | — | — | EP | disclosed |
| US-7968581-B2 | Imidazolidine compounds as androgen receptor modulators | GALAPAGOS NV (BE) | 2011-06-28 | — | — | US | disclosed |
| US-7968581-B2 | Imidazolidine compounds as androgen receptor modulators | GALAPAGOS NV (BE) | 2011-06-28 | — | — | US | disclosed |
| US-7968581-B2 | Imidazolidine compounds as androgen receptor modulators | GALAPAGOS NV (BE) | 2011-06-28 | — | — | US | disclosed |
| CN-102102111-A | Method for synthesizing optically-active aryl vicinal diol under catalysis of plant cells | UNIV JIANGNAN | 2011-06-22 | — | — | CN | disclosed |
| US-20110112118-A1 | 2,4-Diaminoquinazolines for Spinal Muscular Atrophy | FAMILIES OF SPINAL MUSCULAR ATROPHY (US) | 2011-05-12 | — | — | US | disclosed |
| US-7902186-B2 | Substituted 5-phenyl-3,6-dihydro-2-oxo-6H-1,3,4-thiadiazines | MERCK PATENT GMBH (DE) | 2011-03-08 | — | — | US | disclosed |
| US-7888366-B2 | 2,4-diaminoquinazolines for spinal muscular atrophy | FAMILIES OF SPINAL MUSCULAR ATROPHY (US) | 2011-02-15 | — | — | US | disclosed |
| WO-2011015728-A1 | NOVEL DIHYDROINDOLONE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2011-02-10 | — | — | WO | disclosed |
| US-20110034460-A1 | Dihydroindolone compounds, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2011-02-10 | — | — | US | disclosed |
| EP-2280951-A2 | PROCESSES FOR THE PREPARATION OF BENZO-FUSED DIOXIN DERIVATIVES | Janssen Pharmaceutica, N.V. (BE) | 2011-02-09 | — | — | EP | disclosed |
| EP-2281822-A1 | New dihydroindolone derivatives, method of preparing same and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2011-02-09 | — | — | EP | disclosed |
| WO-2010151593-A1 | STEROSPECIFIC CARBONYL REDUCTASES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2010-12-29 | — | — | WO | disclosed |
| US-20100113547-A1 | NOVEL IMIDAZOLIDINE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | AKASHI THERAPEUTICS, INC. | 2010-05-06 | — | — | US | disclosed |
| US-20100113547-A1 | NOVEL IMIDAZOLIDINE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | AKASHI THERAPEUTICS, INC. | 2010-05-06 | — | — | US | disclosed |
| US-20100113547-A1 | NOVEL IMIDAZOLIDINE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | AKASHI THERAPEUTICS, INC. | 2010-05-06 | — | — | US | disclosed |
| WO-2010029119-A1 | NOVEL IMIDAZOLIDINE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | GALAPAGOS NV (BE) | 2010-03-18 | — | — | WO | disclosed |
| WO-2010029119-A1 | NOVEL IMIDAZOLIDINE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | GALAPAGOS NV (BE) | 2010-03-18 | — | — | WO | disclosed |
| US-20090312313-A1 | COMPOUND HAVING TGFBETA INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 2009-12-17 | — | — | US | disclosed |
| CN-100548960-C | Substituted 1, 3-diphenylprop-2-en-1-one derivatives, their preparation and their use | GENFIT (FR) | 2009-10-14 | — | — | CN | disclosed |
| WO-2009120192-A2 | PROCESS FOR THE PREPARATION OF BENZO-FUSED HETEROARYL DERIVATIVES | JASSEN PHARMACEUTICA, N.V. (BE) | 2009-10-01 | — | — | WO | disclosed |
| US-20090247618-A1 | PROCESS FOR PREPARATION OF BENZO-FUSED HETEROARYL DERIVATIVES | JANSSEN PHARMACEUTICA, N.C. (BE) | 2009-10-01 | — | — | US | disclosed |
| CN-101541809-A | Spiroketone acetyl-CoA carboxylase inhibitors | PFIZER PROD INC (US) | 2009-09-23 | — | — | CN | disclosed |
| US-7572910-B2 | Pyridazinone aldose reductase inhibitors | PFIZER, INC. (US) | 2009-08-11 | — | — | US | disclosed |
| US-7560558-B2 | Compound having TGFβ inhibitory activity and medicinal composition containing the same | KIRIN BEER KABUSHIKI KAISHA (JP) | 2009-07-14 | — | — | US | disclosed |
| US-7507761-B2 | Benzopyran derivatives, method of production and use thereof | UNIVERSITE DE LIEGE (BE) | 2009-03-24 | — | — | US | disclosed |
| US-20080318936-A1 | Substituted 5-Phenyl-3,6-Dihydro-2-Oxo-6H-1,3,4-Thiadiazines | MERCK PATENT GESELLSCHAFT (DE) | 2008-12-25 | — | — | US | disclosed |
| CN-101321766-A | Substituted benzofused derivatives and their use as vanilloid receptor ligands | GLENMARK PHARMACEUTICALS SA (CH) | 2008-12-10 | — | — | CN | disclosed |
| US-7456187-B2 | Furanopyrimidine compounds as potassium ion channel inhibitors | XENTION LIMITED (GB) | 2008-11-25 | — | — | US | disclosed |
| EP-1951697-A1 | SUBSTITUTED 5-PHENYL-3,6-DIHYDRO-2-OXO-6H-[1,3,4]THIADIAZINES | Merck Patent GmbH (DE) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007057092-A1 | SUBSTITUTED 5-PHENYL-3,6-DIHYDRO-2-OXO-6H-[1,3,4]THIADIAZINES | MERCK PATENT GMBH (DE) | 2007-05-24 | — | — | WO | disclosed |
| US-20070112063-A1 | Benzopyran derivatives, method of production and use thereof | UNIVERSITE DE LIEGE (BE) | 2007-05-17 | — | — | US | disclosed |
| EP-1221440-B1 | Benzoheterocyclic derivatives useful as vasopressin or oxytocin modulators | OTSUKA PHARMA CO LTD (JP) | 2007-04-25 | — | — | EP | disclosed |
| EP-1765810-A1 | 2,4-DIAMINOQUINAZOLINES FOR SPINAL MUSCULAR ATROPHY | Decode Chemistry, Inc. (US) | 2007-03-28 | — | — | EP | disclosed |
| EP-1758909-A1 | FURANOPYRIMIDINE COMPOUNDS EFFECTIVE AS POTASSIUM CHANNEL INHIBITORS | Xention Limited (GB) | 2007-03-07 | — | — | EP | disclosed |
| EP-1491541-B1 | Pyridazinone aldose reductase inhibitors | PFIZER PROD INC (US) | 2007-01-24 | — | — | EP | disclosed |
| EP-1716141-A1 | BENZOPYRAN DERIVATIVES, METHOD OF PRODUCTION AND USE THEREOF | Université de Liège (BE) | 2006-11-02 | — | — | EP | disclosed |
| EP-0841925-B1 | ENDOTHELIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2006-10-04 | — | — | EP | disclosed |
| US-20060111375-A1 | Compound having tgfß inhibitory activity and medicinal composition containing the same | KIRIN BEER KABUSHIKI KAISHA (JP) | 2006-05-25 | — | — | US | disclosed |
| WO-2005123724-A1 | 2,4-DIAMINOQUINAZOLINES FOR SPINAL MUSCULAR ATROPHY | DECODE CHEMISTRY, INC. (US) | 2005-12-29 | — | — | WO | disclosed |
| US-20050288314-A1 | 2,4-diaminoquinazolines for spinal muscular atrophy | DECODE CHEMISTRY, INC. (US) | 2005-12-29 | — | — | US | disclosed |
| WO-2005121149-A1 | FURANOPYRIMIDINE COMPOUNDS EFFECTIVE AS POTASSIUM CHANNEL INHIBITORS | XENTION DISCOVERY LIMITED (GB) | 2005-12-22 | — | — | WO | disclosed |
| US-20050282829-A1 | Furanopyrimidine compounds as potassium ion channel inhibitors | XENTION DISCOVERY LTD. (GB) | 2005-12-22 | — | — | US | disclosed |
| EP-1589015-A1 | Benzopyran derivatives, method of production and use thereof | Université de Liège (BE) | 2005-10-26 | — | — | EP | disclosed |
| CN-1688532-A | Compositions based on substituted 1, 3-diphenylprop-2-en-1-one derivatives, preparation and use thereof | GENFIT (FR) | 2005-10-26 | — | — | CN | disclosed |
| CN-1668565-A | Substituted 1, 3-diphenylprop-2-en-1-one derivatives, their preparation and their use | GENFIT (FR) | 2005-09-14 | — | — | CN | disclosed |
| WO-2005075463-A1 | BENZOPYRAN DERIVATIVES, METHOD OF PRODUCTION AND USE THEREOF | UNIVERSITE DE LIEGE (BE) | 2005-08-18 | — | — | WO | disclosed |
| CN-1215067-C | Pyridazinone aldose reductase inhibitors | PFIZER PROD INC (US) | 2005-08-17 | — | — | CN | disclosed |
| EP-1548008-A1 | COMPOUND HAVING TGF-BETA INHIBITORY ACTIVITY AND MEDICINAL COMPOSITION CONTAINING THE SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 2005-06-29 | — | — | EP | disclosed |
| CN-1204128-C | Process for preparing oxazole derivatives | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2005-06-01 | — | — | CN | disclosed |
| US-20050113381-A1 | Pyridazinone aldose reductase inhibitors | MYLARI BANAVARA L (US) | 2005-05-26 | — | — | US | disclosed |
| CN-1196692-C | Substituted benzopyran derivatives for the treatment of inflammation | SEARLE & CO (US) | 2005-04-13 | — | — | CN | disclosed |
| US-6849629-B2 | Heteroaromatic substituted sulfonyl or sulfoxide or thio-pyridazinone derivatives, useful for treating diabetic complications and cardiovascular disorders | PFIZER, INC. (US) | 2005-02-01 | — | — | US | disclosed |
| US-20050004124-A1 | THERAPIES RELATING TO COMBINATIONS OF ALDOSE REDUCTASE INHIBITORS AND CYCLOOXYGENASE-2 INHIBITORS | MYLARI BANAVARA L (US) | 2005-01-06 | — | — | US | disclosed |
| EP-1373259-B1 | PYRIDAZINONE ALDOSE REDUCTASE INHIBITORS | PFIZER PROD INC (US) | 2004-12-29 | — | — | EP | disclosed |
| US-20040198740-A1 | Therapies relating to combinations of aldose reductase inhibitors and cyclooxygenase-2 | PFIZER INC | 2004-10-07 | — | — | US | disclosed |
| CN-1515566-A | Substituted chromene derivative for curing inflammation | G.D. | 2004-07-28 | — | — | CN | disclosed |
| CN-1505514-A | Combination of aldose reductase inhibitors with cyclooxygenase-2 inhibitors | �Ʒ� | 2004-06-16 | — | — | CN | disclosed |
| CN-1500087-A | Pyridazinone aldose reductase inhibitors | �Ʒ� | 2004-05-26 | — | — | CN | disclosed |
| EP-1392310-A1 | COMBINATIONS OF ALDOSE REDUCTASE INHIBITORS AND CYCLOOXYGENASE-2 INHIBITORS | Pfizer Products Inc. (US) | 2004-03-03 | — | — | EP | disclosed |
| US-6699995-B1 | ALKYLATION AT 5-POSITION OF OXAZOLE BY REACTION WITH UNSATURATED COMPOUND IN PRESENCE OF ACID OR BASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| EP-1219610-B1 | PROCESS FOR THE PREPARATION OF OXAZOLE DERIVATIVES | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-02-25 | — | — | EP | disclosed |
| EP-1373259-A1 | PYRIDAZINONE ALDOSE REDUCTASE INHIBITORS | Pfizer Products Inc. (US) | 2004-01-02 | — | — | EP | disclosed |
| US-6642223-B2 | A benzoazepin or benzodiazepin derivatives, shows excellent anti-vasopressin activity, vasopressin agonistic activity and oxytocin antagonistic activity, and are useful as antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2003-11-04 | — | — | US | disclosed |
| US-20030162784-A1 | Pyridazinone aldose reductase inhibitors | MYLARI BANAVARA L (US) | 2003-08-28 | — | — | US | disclosed |
| US-6579879-B2 | Pyridazinone aldose reductase inhibitors | PFIZER INC | 2003-06-17 | — | — | US | disclosed |
| CN-1384824-A | Process for preparing oxazole derivatives | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-12-11 | — | — | CN | disclosed |
| US-6482956-B2 | FOR THERAPY OF CARDIOVASCULAR, CEREBROVASCULAR, RESPIRATORY AND RENAL DISORDERS | SMITHKLINE BEECHAM CORPORATION | 2002-11-19 | — | — | US | disclosed |
| WO-2002087584-A1 | COMBINATIONS OF ALDOSE REDUCTASE INHIBITORS AND CYCLOOXYGENASE-2 INHIBITORS | PFIZER PRODUCTS INC. (US) | 2002-11-07 | — | — | WO | disclosed |
| WO-2002079198-A1 | PYRIDAZINONE ALDOSE REDUCTASE INHIBITORS | PFIZER PRODUCTS INC. (US) | 2002-10-10 | — | — | WO | disclosed |
| US-20020143017-A1 | Pyridazinone aldose reductase inhibitors | MYLARI BANAVARA L (US) | 2002-10-03 | — | — | US | disclosed |
| EP-1221440-A1 | Benzoheterocyclic derivatives useful as vasopressin or oxytocin modulators | Otsuka Pharmaceutical Company, Limited (JP) | 2002-07-10 | — | — | EP | disclosed |
| US-20020072614-A1 | Endothelin receptor antagonists | LUENGO JUAN IGNACIO (US) | 2002-06-13 | — | — | US | disclosed |
| US-20020049194-A1 | Benzoheterocyclic derivatives | OGAWA HIDENORI (JP) | 2002-04-25 | — | — | US | disclosed |
| US-6353116-B1 | Endothelin receptor antagonists | SMITHKLINE BEECHAM CORPORATION | 2002-03-05 | — | — | US | disclosed |
| US-6335327-B1 | Benzoheterocyclic derivatives | OTSUKA PHARMACEUTICALS CO., LTD. (JP) | 2002-01-01 | — | — | US | disclosed |
| EP-0841925-A4 | ENDOTHELIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2001-10-17 | — | — | EP | disclosed |
| EP-0686636-B1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| US-6096735-A | Benzoheterocyclic derivatives | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 2000-08-01 | — | — | US | disclosed |
| US-6096897-A | NOVEL 1,2,3-TRIAZOLES | SMITHKLINE BEECHAM CORPORATION (US) | 2000-08-01 | — | — | US | disclosed |
| CN-1257489-A | Substituted benzopyran derivatives for the treatment of inflammation | SEARLE & CO (US) | 2000-06-21 | — | — | CN | disclosed |
| US-5972946-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| US-5969151-A | PYRAZOLE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-10-19 | — | — | US | disclosed |
| US-5968975-A | TREATING ATHEROSCLEROSIS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-10-19 | — | — | US | disclosed |
| US-5958968-A | CARDIOVASCULAR DISORDERS; KIDNEY DIEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1999-09-28 | — | — | US | disclosed |
| WO-1999031089-A1 | 1-(1H-IMIDAZOL-2-YL)PYRROLIDINE AND 1-(1H-IMIDAZOL-2-YLPIPERIDINE) DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION | SANOFI-SYNTHELABO (FR) | 1999-06-24 | — | — | WO | disclosed |
| WO-1998057925-A1 | ELEVATION OF HDL CHOLESTEROL BY 2-[(AMINOTHIOXOMETHYL)-HYDRAZONO]-2-ARYLETHYL CARBAMATES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-12-23 | — | — | WO | disclosed |
| US-5840895-A | INTERMEDIATES FOR ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1998-11-24 | — | — | US | disclosed |
| CN-1196680-A | Endothelin receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1998-10-21 | — | — | CN | disclosed |
| EP-0841925-A1 | ENDOTHELIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-05-20 | — | — | EP | disclosed |
| US-5753642-A | AGRICULTURE, MEDICINE | ROHM AND HAAS COMPANY (US) | 1998-05-19 | — | — | US | disclosed |
| EP-0624163-B1 | CYCLIC CALCITONIN DERIVATIVES AND METHOD FOR THEIR PRODUCTION | SMITHKLINE BEECHAM FARMA (IT) | 1998-03-25 | — | — | EP | disclosed |
| US-5728698-A | AGRICULTURAL USE, RICE, WHEAT | ROHM AND HAAS COMPANY (US) | 1998-03-17 | — | — | US | disclosed |
| US-5728715-A | FOR MAMMALS, AGRICULTURE, RICE, WHEAT, TOMATOES | ROHM AND HAAS COMPANY (US) | 1998-03-17 | — | — | US | disclosed |
| US-5728694-A | Dihydropyridazinones, pyridazinones and related compounds as fungicides | ROHM AND HAAS COMPANY (US) | 1998-03-17 | — | — | US | disclosed |
| US-5726162-A | FOR CONTROLLING AGRICULTURAL AND MAMMALIAN FUNGAL DISEASES | ROHM AND HAAS COMPANY (US) | 1998-03-10 | — | — | US | disclosed |
| US-5726176-A | FOR CONTROLLING AGRICULTURAL AND MAMMALIAN FUNGAL DISEASES | ROHM AND HAAS COMPANY (US) | 1998-03-10 | — | — | US | disclosed |
| CN-1037511-C | Therapeutic agents | BOOTS CO PLC (GB) | 1998-02-25 | — | — | CN | disclosed |
| US-5686442-A | ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-11-11 | — | — | US | disclosed |
| US-5631254-A | RICE; HUMAN INFECTIONS | ROHM AND HAAS COMPANY (US) | 1997-05-20 | — | — | US | disclosed |
| CN-1148593-A | Production method for chromone derivative and its medicinal composition | KUREHA CHEMICAL IND CO LTD (JP) | 1997-04-30 | — | — | CN | disclosed |
| EP-0765314-A1 | BENZOHETEROCYCLIC DERIVATIVES USEFUL AS VASOPRESSIN OR OXYTOCIN MODULATORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-02 | — | — | EP | disclosed |
| WO-1997004772-A1 | ENDOTHELIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-02-13 | — | — | WO | disclosed |
| US-5552409-A | PHYTOPATHOGENIC, RICE | ROHM AND HAAS COMPANY (US) | 1996-09-03 | — | — | US | disclosed |
| EP-0486029-B1 | Photographic elements containing release compounds-II | EASTMAN KODAK CO (US) | 1996-01-24 | — | — | EP | disclosed |
| WO-1995034540-A1 | BENZOHETEROCYCLIC DERIVATIVES USEFUL AS VASOPRESSIN OR OXYTOCIN MODULATORS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-12-21 | — | — | WO | disclosed |
| EP-0686636-A1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-12-13 | — | — | EP | disclosed |
| CN-1096781-A | The therapeutical agent that contains 1-(aralkyl-aminoalkyl) imidazolium compounds | BOOTS CO PLC (GB) | 1994-12-28 | — | — | CN | disclosed |
| US-5371098-A | Use of oxazole compounds to treat osteoporosis | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-06 | — | — | US | disclosed |
| EP-0624163-A1 | CYCLIC CALCITONIN DERIVATIVES AND METHOD FOR THEIR PRODUCTION | Smithkline Beecham Farmaceutici S.p.A. (IT) | 1994-11-17 | — | — | EP | disclosed |
| EP-0618907-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | Knoll AG (DE) | 1994-10-12 | — | — | EP | disclosed |
| US-5239080-A | Oxazole compounds and their use as antidiabetic and bone-reduction inhibitory agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-08-24 | — | — | US | disclosed |
| WO-1993015106-A1 | CYCLIC CALCITONINE DERIVATIVES AND METHOD FOR THEIR PRODUCTION | SMITHKLINE BEECHAM FARMACEUTICI S.P.A. (IT) | 1993-08-05 | — | — | WO | disclosed |
| EP-0181121-B1 | NOVEL POLYPEPTIDE AND PROCESS FOR PRODUCING THE SAME | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1992-12-30 | — | — | EP | disclosed |
| EP-0486029-A1 | Photographic elements containing release compounds-II | EASTMAN KODAK COMPANY (US) | 1992-05-20 | — | — | EP | disclosed |
| EP-0478195-A1 | Dihydropyridazinones, pyridazinones and related compounds as fungicides | ROHM AND HAAS COMPANY (US) | 1992-04-01 | — | — | EP | disclosed |
| US-5055385-A | Rapid release from timing group | EASTMAN KODAK COMPANY (US) | 1991-10-08 | — | — | US | disclosed |
| EP-0440183-A1 | Oxazole compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-08-07 | — | — | EP | disclosed |
| EP-0168343-B1 | METAL COMPLEXES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DYEING HIGH-MOLECULAR ORGANIC MATERIALS | CIBA-GEIGY AG (CH) | 1991-05-02 | — | — | EP | disclosed |
| EP-0382199-A1 | Oxazole compounds and their use | Takeda Chemical Industries, Ltd. (JP) | 1990-08-16 | — | — | EP | disclosed |
| US-RE33188-E | Peptides for assaying human parathyroid hormone | TOYO JOZO KABUSHIKI KAISHA (JP) | 1990-03-27 | — | — | US | disclosed |
| EP-0119705-B1 | OCTAPEPTIDE VASOPRESSIN ANTAGONISTS | SMITHKLINE BECKMAN CORPORATION (US) | 1989-09-06 | — | — | EP | disclosed |
| EP-0305952-A1 | Substituted 2-phenyl-4-quinoline-carboxylic acids | AMERICAN CYANAMID COMPANY (US) | 1989-03-08 | — | — | EP | disclosed |
| US-4775747-A | PIGMENTS FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1988-10-04 | — | — | US | disclosed |
| EP-0257521-A2 | 3,4-Dihydro-2H-pyranes and process for their preparation | BASF Aktiengesellschaft (DE) | 1988-03-02 | — | — | EP | disclosed |
| US-4719199-A | VASORPRESSIN ANTAGONIST | SMITHKLINE BECKMAN CORPORATION (US) | 1988-01-12 | — | — | US | disclosed |
| US-4703106-A | REDUCING CALCIUM CONCENTRATION OF BLOOD | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1987-10-27 | — | — | US | disclosed |
| US-4684716-A | VASOPRESSIN ANTAGONISTS | SMITHKLINE BECKMAN CORPORATION (US) | 1987-08-04 | — | — | US | disclosed |
| US-4670486-A | Polymer composition pigmented with copper or nickel complexes of ligands containing a semicarbazone moiety | CIBA-GEIGY CORPORATION (US) | 1987-06-02 | — | — | US | disclosed |
| US-4656250-A | NORLEUCINE, TYROSINE, PHENYLALANINE TREATING HYPOPARATHYROIDISM | TOYO JOZO KABUSHIKI KAISHA (JP) | 1987-04-07 | — | — | US | disclosed |
| US-4639477-A | AZO DYES | CIBA-GEIGY CORPORATION (US) | 1987-01-27 | — | — | US | disclosed |
| US-4597901-A | POLYPEPTIDES, DIURESIS | SMITHKLINE BECKMAN CORPORATION (US) | 1986-07-01 | — | — | US | disclosed |
| EP-0181121-A2 | Novel polypeptide and process for producing the same | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1986-05-14 | — | — | EP | disclosed |
| US-4587045-A | Intermediates for preparing octapeptide vasopressin antagonists | SMITHKLINE BECKMAN CORPORATION (US) | 1986-05-06 | — | — | US | disclosed |
| EP-0169167-A2 | Process for dyeing high-molecular organic materials, and metal complexes | CIBA-GEIGY AG (CH) | 1986-01-22 | — | — | EP | disclosed |
| EP-0168343-A2 | Metal complexes, process for their preparation and their use in dyeing high-molecular organic materials | CIBA-GEIGY AG (CH) | 1986-01-15 | — | — | EP | disclosed |
| US-4542124-A | Octapeptide vasopressin antagonists | SMITHKLINE BECKMAN CORPORATION (US) | 1985-09-17 | — | — | US | disclosed |
| EP-0119705-A2 | Octapeptide vasopressin antagonists | SMITHKLINE BECKMAN CORPORATION (US) | 1984-09-26 | — | — | EP | disclosed |
| US-4409141-A | Peptides for assaying human parathyroid hormone | TOYO JOZO KABUSHIKI KAISHA (JP) | 1983-10-11 | — | — | US | disclosed |
| US-4400316-A | POLYPEPTIDES | TOYO JOZO KABUSHIKI KAISHA (JP) | 1983-08-23 | — | — | US | disclosed |
| US-4265903-A | HYPOTENSIVE, ADRENOLYTIC | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1981-05-05 | — | — | US | disclosed |
| US-4258193-A | FOR IMMOBILIZATION; IMMUNOASSAY, CROSSLINKING OF PROTEINS | TOYO JOZO KABUSHIKI KAISHA (JP) | 1981-03-24 | — | — | US | disclosed |
| US-4133814-A | ANTITUMOR AGENTS | ELI LILLY AND COMPANY (US) | 1979-01-09 | — | — | US | disclosed |
| US-4122256-A | OPTICAL BRIGHTENERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-10-24 | — | — | US | disclosed |
| US-4086221-A | SERUM CALCIUM REDUCING ACTIVITY | TOYO JOZO KABUSHIKI KAISHA (JA) | 1978-04-25 | — | — | US | disclosed |
| US-4076717-A | Derivatives of 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylic acid | G. D. SEARLE & CO. (US) | 1978-02-28 | — | — | US | disclosed |
| US-4075227-A | NONSTEROIDAL | ELI LILLY AND COMPANY (US) | 1978-02-21 | — | — | US | disclosed |
| US-4075223-A | NONSTEROIDAL | ELI LILLY AND COMPANY (US) | 1978-02-21 | — | — | US | disclosed |
| US-4052212-A | ETHER-ESTER | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) | 1977-10-04 | — | — | US | disclosed |
| US-4017546-A | AROYL PHENYL INDENES AND AROYL PHENYL NAPHTHALENES | ELI LILLY AND COMPANY (US) | 1977-04-12 | — | — | US | disclosed |
| US-3994879-A | CONDENSING AZOMETHINES, OPTICAL BRIGHTENERS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-11-30 | — | — | US | disclosed |
| US-3933918-A | ANTITUSSIVE | KYOWA HAKKO KOGYO CO., LTD. (JA) | 1976-01-20 | — | — | US | disclosed |
| US-3933918-A | ANTITUSSIVE | KYOWA HAKKO KOGYO CO., LTD. (JA) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (35 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110112118-A1 | 2,4-Diaminoquinazolines for Spinal Muscular Atrophy | SMN1; SMN2, MUSK, MYO3B | GSK3B 2837/4885ERCC5 2748/4885FEN1 2491/4885 |
| US-20120178718-A1 | NOVEL IMIDAZOLIDINE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | AR, FSHR, GNRHR | GSK3B 2141/4885ERCC5 3695/4885FEN1 4185/4885 |
| US-20160152577-A1 | 2,4-Diaminoquinazolines for Spinal Muscular Atrophy | SMN1; SMN2, MUSK, MYO3B | GSK3B 2837/4885ERCC5 2748/4885FEN1 2491/4885 |
| US-10085450-B2 | Tetrazolinone compound and use thereof | ROS1, TCOF1, RPS20 | GSK3B 2556/4885ERCC5 3994/4885FEN1 4197/4885 |
| US-20050288314-A1 | 2,4-diaminoquinazolines for spinal muscular atrophy | SMN1; SMN2, MUSK, MYO3B | GSK3B 2837/4885ERCC5 2748/4885FEN1 2491/4885 |
| US-20060111375-A1 | Compound having tgfß inhibitory activity and medicinal composition containing the same | TGFB1, TGFBR1, TGFBR2 | GSK3B 42/4885ERCC5 3113/4885FEN1 4211/4885 |
| US-20050113381-A1 | Pyridazinone aldose reductase inhibitors | SLC5A1, ALDOA, AKR1B1 | GSK3B 106/4885ERCC5 1613/4885FEN1 722/4885 |
| US-11236104-B2 | Heteroaromatic NMDA receptor modulators and uses thereof | GRIN2C, GRIN2A, GRIN1 | GSK3B 2070/4885ERCC5 3306/4885FEN1 4163/4885 |
| US-20100113547-A1 | NOVEL IMIDAZOLIDINE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | AR, FSHR, GNRHR | GSK3B 2317/4885ERCC5 3713/4885FEN1 4039/4885 |
| US-10626122-B2 | Heteroaromatic NMDA receptor modulators and uses thereof | GRIN2C, GRIN2A, GRIN1 | GSK3B 2070/4885ERCC5 3306/4885FEN1 4163/4885 |
| US-12162890-B2 | Heteroaromatic NMDA receptor modulators and uses thereof | GRIN2C, GRIN2A, GRIN1 | GSK3B 2070/4885ERCC5 3306/4885FEN1 4163/4885 |
| US-20020049194-A1 | Benzoheterocyclic derivatives | AVPR2, AVPR1A, AVPR1B | GSK3B 4867/4885ERCC5 2265/4885FEN1 4036/4885 |
| US-20180362541-A1 | HETEROAROMATIC NMDA RECEPTOR MODULATORS AND USES THEREOF | GRIN2C, GRIN2A, GRIN1 | GSK3B 2070/4885ERCC5 3306/4885FEN1 4163/4885 |
| US-20130331380-A1 | DIHYDROINDOLONE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CYP11B1, SDHA, CYP11B2 | GSK3B 1512/4885ERCC5 3118/4885FEN1 4283/4885 |
| US-20030162784-A1 | Pyridazinone aldose reductase inhibitors | SLC5A1, ALDOA, AKR1B1 | GSK3B 106/4885ERCC5 1613/4885FEN1 722/4885 |
| US-20070112063-A1 | Benzopyran derivatives, method of production and use thereof | CBR3, CBR1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | GSK3B 4858/4885ERCC5 2252/4885FEN1 3366/4885 |
| US-20020143017-A1 | Pyridazinone aldose reductase inhibitors | SLC5A1, AKR1B1, AKR1D1 | GSK3B 212/4885ERCC5 1754/4885FEN1 431/4885 |
| US-20150031733-A1 | TETRAZOLINONE COMPOUNDS AND ITS USE | CBR3, CYP51A1, CYP8B1 | GSK3B 2675/4885ERCC5 3795/4885FEN1 4540/4885 |
| US-20050004124-A1 | THERAPIES RELATING TO COMBINATIONS OF ALDOSE REDUCTASE INHIBITORS AND CYCLOOXYGENASE-2 INHIBITORS | ALDOA, AKR1B1, ALDH2 | GSK3B 1186/4885ERCC5 3040/4885FEN1 1381/4885 |
| US-20120046287-A1 | Dihydroindolone compounds, a process for their preparation and pharmaceutical compositions containing them | CYP11B1, SDHA, CYP11B2 | GSK3B 1512/4885ERCC5 3118/4885FEN1 4283/4885 |
| US-20050282829-A1 | Furanopyrimidine compounds as potassium ion channel inhibitors | KCNH3, HCN4, KCNH2 | GSK3B 4196/4885ERCC5 1978/4885FEN1 3895/4885 |
| US-20110282018-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | WEE2, NOTUM, WEE1 | GSK3B 2564/4885ERCC5 1337/4885FEN1 526/4885 |
| US-20090312313-A1 | COMPOUND HAVING TGFBETA INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | TGFB1, TGFBR1, TGFBR2 | GSK3B 37/4885ERCC5 3577/4885FEN1 4416/4885 |
| US-20040198740-A1 | Therapies relating to combinations of aldose reductase inhibitors and cyclooxygenase-2 | ALDOA, ALDH2, AKR1B1 | GSK3B 1291/4885ERCC5 3225/4885FEN1 1448/4885 |
| US-20080318936-A1 | Substituted 5-Phenyl-3,6-Dihydro-2-Oxo-6H-1,3,4-Thiadiazines | ABL1, RET, ERBB2 | GSK3B 937/4885ERCC5 4082/4885FEN1 3190/4885 |
| US-20090247618-A1 | PROCESS FOR PREPARATION OF BENZO-FUSED HETEROARYL DERIVATIVES | CYP3A4, CYP3A5, CYP1A2 | GSK3B 1798/4885ERCC5 1765/4885FEN1 2662/4885 |
| US-20230023543-A1 | HETEROAROMATIC NMDA RECEPTOR MODULATORS AND USES THEREOF | GRIN2C, GRIN2A, GRIN1 | GSK3B 2070/4885ERCC5 3306/4885FEN1 4163/4885 |
| US-20110034460-A1 | Dihydroindolone compounds, a process for their preparation and pharmaceutical compositions containing them | CYP11B1, SDHA, CYP11B2 | GSK3B 1512/4885ERCC5 3118/4885FEN1 4283/4885 |
| US-20210107916-A1 | HETEROAROMATIC NMDA RECEPTOR MODULATORS AND USES THEREOF | GRIN2C, GRIN2A, GRIN1 | GSK3B 2070/4885ERCC5 3306/4885FEN1 4163/4885 |
| US-20200325147-A1 | Compounds Useful in HIV Therapy | CCR5, CD4, G6PD | GSK3B 1516/4885ERCC5 2682/4885FEN1 2356/4885 |
| US-20130281709-A1 | PROCESS FOR PRODUCING ALPHA-HYDROXYKETONE COMPOUND | BCKDK, KHK, PDK4 | GSK3B 845/4885ERCC5 4162/4885FEN1 3352/4885 |
| US-11274102-B2 | Compounds useful in HIV therapy | CCR5, CD4, G6PD | GSK3B 1516/4885ERCC5 2682/4885FEN1 2356/4885 |
| US-20140235867-A1 | METHOD FOR PRODUCING ALPHA-HYDROXY KETONE COMPOUND | HSD17B7, BCKDK, HSD11B1 | GSK3B 606/4885ERCC5 4358/4885FEN1 2201/4885 |
| US-20020072614-A1 | Endothelin receptor antagonists | EDNRA, EDNRB, ECE1 | GSK3B 4124/4885ERCC5 1377/4885FEN1 839/4885 |
| US-20160270399-A1 | TETRAZOLINONE COMPOUND AND USE THEREOF | ROS1, TCOF1, RPS20 | GSK3B 2556/4885ERCC5 3994/4885FEN1 4197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.