Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 known ✓ | Q9BY41 | 5/20 | 0.40 |
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.37 |
| ▸ | HRH1 known ✓ | P35367 | 1/20 | 0.37 |
| ▸ | PDE4D known ✓ | Q08499 | 1/20 | 0.37 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31124474 | 1.00 | USP2 (0.41) | USP2HDAC8ACHETSHRHRH1 | |
| SCHEMBL272532 | 0.98 | USP2 (0.42) | USP2HDAC8ACHETSHRHRH1 | |
| Acetic Acid SCHEMBL149422 | 0.82 | HDAC8 (0.43) | USP2HDAC8ACHETSHRHRH1 | |
| Hydrochloric Acid SCHEMBL28336457 | 0.81 | HDAC8 (0.41) | HDAC8ACHETSHRHRH1PDE4D | |
| Hydrochloric Acid SCHEMBL28837202 | 0.79 | NNMT (0.41) | HDAC8ACHETSHRHRH1PDE4D | |
| SCHEMBL13113036 | 0.78 | HDAC8 (0.43) | HDAC8ACHETSHRHRH1PDE4D | |
| SCHEMBL29922 | 0.78 | HDAC8 (0.48) | HDAC8ACHETSHRHRH1PDE4D | |
| SCHEMBL546287 | 0.77 | NNMT (0.42) | HDAC8ACHETSHRHRH1PDE4D | |
| Hydrochloric Acid SCHEMBL11768005 | 0.77 | HDAC8 (0.41) | HDAC8ACHETSHRHRH1PDE4D | |
| Hydrochloric Acid SCHEMBL150596 | 0.77 | HDAC8 (0.46) | HDAC8ACHETSHRHRH1PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250312265-A1 | CROSSLINKED MATERIALS | FOUNT BIO, INC. | 2025-10-09 | — | — | US | disclosed |
| US-12419824-B2 | Compounds useful for the treatment and/or care of the skin, hair, nails and/or mucous membranes | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2025-09-23 | — | — | US | disclosed |
| US-12311048-B2 | Crosslinked materials | FOUNT BIO, INC. (US) | 2025-05-27 | — | — | US | disclosed |
| EP-4192419-B1 | EMULSIFIER COMPOSITION FOR PERSONAL CARE FORMULATION | LUBRIZOL ADVANCED MAT INC (US) | 2025-04-16 | — | — | EP | disclosed |
| US-20240180989-A1 | LIGUSTRUM LUCIDUM EXTRACT USEFUL FOR THE TREATMENT AND/OR CARE OF THE SKIN | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2024-06-06 | — | — | US | disclosed |
| US-11896704-B2 | Compounds useful for the treatment and/or care of the skin, hair, nails and/or mucous membranes | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2024-02-13 | — | — | US | disclosed |
| US-20230301898-A1 | EMULSIFIER COMPOSITION FOR PERSONAL CARE FORMULATION | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2023-09-28 | — | — | US | disclosed |
| US-20230190616-A1 | COMPOUNDS USEFUL FOR THE TREATMENT AND/OR CARE OF THE SKIN, HAIR, NAILS AND/OR MUCOUS MEMBRANES | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2023-06-22 | — | — | US | disclosed |
| US-20230172925-A1 | SKIN-CARE COMPOSITIONS AND USES THEREOF | AHAVA - DEAD SEA LABORATORIES LTD. (IL) | 2023-06-08 | — | — | US | disclosed |
| US-20230165780-A1 | CROSSLINKED MATERIALS | FOUNT BIO, INC. | 2023-06-01 | — | — | US | disclosed |
| US-20200214960-A1 | COMPOUNDS USEFUL FOR THE TREATMENT AND/OR CARE OF THE SKIN, HAIR, NAILS AND/OR MUCOUS MEMBRANES | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2020-07-09 | — | — | US | disclosed |
| EP-2399648-B1 | Cosmetic composition and use of same | LR HEALTH & BEAUTY SYSTEMS GMBH (DE) | 2018-04-04 | — | — | EP | disclosed |
| EP-3124033-A1 | POST-PROCEDURE WOUND HEALING SKIN CARE COMPOSITION | Zo Skin Health, Inc. (US) | 2017-02-01 | — | — | EP | disclosed |
| US-9248160-B1 | Post-procedure skin care systems, compositions, and methods of use thereof | ZO SKIN HEALTH, INC. (US) | 2016-02-02 | — | — | US | disclosed |
| US-20150050331-A1 | METHOD FOR MAKING A TOPICAL COMPOSITION COMPRISING GROWTH FACTORS DERIVED FROM HUMAN UMBILICAL CORD BLOOD PLATELETS | NOVO SOLUTIONS MD, LLC (US) | 2015-02-19 | — | — | US | disclosed |
| US-8354099-B2 | Skin-care compositions and uses thereof | AHAVA-DEAD SEA LABORATORIES LTD. (IL) | 2013-01-15 | — | — | US | disclosed |
| EP-2174648-B1 | Skin-care compositions and uses thereof | AHAVA DEAD SEA LAB LTD (IL) | 2012-06-20 | — | — | EP | disclosed |
| EP-2399648-A2 | Cosmetic composition and use of same | LR Health & Beauty Systems GmbH (DE) | 2011-12-28 | — | — | EP | disclosed |
| US-20100111878-A1 | SKIN-CARE COMPOSITIONS AND USES THEREOF | AHAVA - DEAD SEA LABORATORIES LTD. (IL) | 2010-05-06 | — | — | US | disclosed |
| EP-2174648-A1 | Skin-care compositions and uses thereof | Ahava-Dead Sea Laboratories Ltd. (IL) | 2010-04-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11896704-B2 | Compounds useful for the treatment and/or care of the skin, hair, nails and/or mucous membranes | TYR, MTX1, MTX2 | HDAC8 903/4885ACHE 2130/4885HRH1 800/4885 |
| US-20230190616-A1 | COMPOUNDS USEFUL FOR THE TREATMENT AND/OR CARE OF THE SKIN, HAIR, NAILS AND/OR MUCOUS MEMBRANES | GLA, ALG3, ANXA6 | HDAC8 2777/4885ACHE 2072/4885HRH1 2066/4885 |
| US-20230165780-A1 | CROSSLINKED MATERIALS | DCLRE1A, COL2A1, MTCL3 | HDAC8 2559/4885ACHE 2552/4885HRH1 4482/4885 |
| US-20200214960-A1 | COMPOUNDS USEFUL FOR THE TREATMENT AND/OR CARE OF THE SKIN, HAIR, NAILS AND/OR MUCOUS MEMBRANES | TYR, MTX2, MTX1 | HDAC8 1270/4885ACHE 2204/4885HRH1 696/4885 |
| US-12311048-B2 | Crosslinked materials | DCLRE1A, COL2A1, MTCL3 | HDAC8 2559/4885ACHE 2552/4885HRH1 4482/4885 |
| US-20250312265-A1 | CROSSLINKED MATERIALS | DCLRE1A, MTCL3, COL2A1 | HDAC8 1981/4885ACHE 2554/4885HRH1 4438/4885 |
| US-12419824-B2 | Compounds useful for the treatment and/or care of the skin, hair, nails and/or mucous membranes | TYR, TELO2, MTX2 | HDAC8 3039/4885ACHE 2791/4885HRH1 1189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.