Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3253032 | 0.98 | TP53 (0.33) | KDM4ELMNATP53CYP1A2 | |
| SCHEMBL6369496 | 0.95 | TP53 (0.32) | KDM4ELMNATP53CYP1A2 | |
| SCHEMBL4215424 | 0.95 | TP53 (0.32) | KDM4ELMNATP53CYP1A2 | |
| SCHEMBL4215465 | 0.95 | TP53 (0.32) | KDM4ELMNATP53CYP1A2 | |
| SCHEMBL3975721 | 0.95 | TP53 (0.32) | KDM4ELMNATP53CYP1A2 | |
| SCHEMBL28048632 | 0.81 | LMNA (0.32) | KDM4ELMNACYP1A2 | |
| SCHEMBL1537296 | 0.79 | GRIN2D (0.33) | KDM4ELMNACYP1A2 | |
| SCHEMBL186138 | 0.79 | GRIN2D (0.33) | KDM4ELMNACYP1A2 | |
| SCHEMBL442281 | 0.78 | SLC7A5 (0.30) | — | |
| SCHEMBL935214 | 0.78 | ALDH1A1 (0.42) | KDM4ELMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110734465-B | Preparation method of glucosamine potassium sulfate salt | 山东润德生物科技有限公司 | 2021-05-28 | — | — | CN | claimed |
| CN-112625070-A | Ginsenoside wall-breaking purification technology | 李波 | 2021-04-09 | — | — | CN | claimed |
| CN-110818751-B | Preparation method of glucosamine sulfate sodium chloride double salt | 山东润德生物科技有限公司 | 2020-11-10 | — | — | CN | claimed |
| CN-110669082-B | Purification and separation method of N-acetyl-D-glucosamine | 山东润德生物科技有限公司 | 2020-11-03 | — | — | CN | claimed |
| CN-110818751-A | Preparation method of glucosamine sulfate sodium chloride double salt | 山东润德生物科技有限公司 | 2020-02-21 | — | — | CN | claimed |
| CN-110734465-A | Preparation method of glucosamine potassium sulfate salts | 山东润德生物科技有限公司 | 2020-01-31 | — | — | CN | claimed |
| CN-110669082-A | Purification and separation method of N-acetyl-D-glucosamine | 山东润德生物科技有限公司 | 2020-01-10 | — | — | CN | claimed |
| CN-110590869-A | Preparation method of N-acetylglucosamine | 山东润德生物科技有限公司 | 2019-12-20 | — | — | CN | claimed |
| CN-106008615-B | The method that chitin prepares 2-acetylamino-2-deoxy-D-glucose | 江苏澳新生物工程有限公司 | 2018-07-13 | — | — | CN | claimed |
| CN-106008615-A | Method for preparing N-acetyl-D-glucosamine from chitin | 江苏澳新生物工程有限公司 | 2016-10-12 | — | — | CN | claimed |
| CN-117866020-A | Crystallization method of glucosamine sulfate sodium chloride double salt | 精晶药业股份有限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-220276973-U | Glucosamine sulfate sodium chloride double salt preparation facilities | 浙江亚峰药厂有限公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-216062967-U | Glucosamine potassium sulfate mixing arrangement | 技源生物制品(徐州)有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-110734465-B | Preparation method of glucosamine potassium sulfate salt | 山东润德生物科技有限公司 | 2021-05-28 | — | — | CN | disclosed |
| CN-110734465-B | Preparation method of glucosamine potassium sulfate salt | 山东润德生物科技有限公司 | 2021-05-28 | — | — | CN | disclosed |
| CN-110669082-A | Purification and separation method of N-acetyl-D-glucosamine | 山东润德生物科技有限公司 | 2020-01-10 | — | — | CN | disclosed |
| CN-110669082-A | Purification and separation method of N-acetyl-D-glucosamine | 山东润德生物科技有限公司 | 2020-01-10 | — | — | CN | disclosed |
| CN-110590869-A | Preparation method of N-acetylglucosamine | 山东润德生物科技有限公司 | 2019-12-20 | — | — | CN | disclosed |
| CN-110590869-A | Preparation method of N-acetylglucosamine | 山东润德生物科技有限公司 | 2019-12-20 | — | — | CN | disclosed |
| CN-106008615-B | The method that chitin prepares 2-acetylamino-2-deoxy-D-glucose | 江苏澳新生物工程有限公司 | 2018-07-13 | — | — | CN | disclosed |