L-Nio

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	L-Nio SCHEMBL30728400	1.00	NOS2 (0.96)	NOS2NOS1NOS3CYP2C19MEN1
	L-Nio SCHEMBL15944942	0.98	NOS2 (1.00)	NOS2NOS1NOS3CYP2C19MEN1
	L-Nil SCHEMBL30703422	0.95	NOS2 (1.00)	NOS2NOS1NOS3CYP2C19MEN1
	L-Nil SCHEMBL31294843	0.95	NOS2 (1.00)	NOS2NOS1NOS3CYP2C19MEN1
	L-Nil SCHEMBL26908936	0.93	NOS2 (1.00)	NOS2NOS1NOS3CYP2C19MEN1
	L-Nil SCHEMBL26908438	0.93	NOS2 (1.00)	NOS2NOS1NOS3CYP2C19MEN1
	Arginine SCHEMBL31591103	0.85	NOS2 (0.89)	NOS2NOS1NOS3CYP2C19MEN1
	Arginine SCHEMBL30074239	0.85	NOS2 (0.96)	NOS2NOS1NOS3CYP2C19MEN1
	Arginine SCHEMBL29361849	0.85	NOS2 (0.96)	NOS2NOS1NOS3CYP2C19MEN1
	Arginine SCHEMBL43261	0.82	NOS2 (1.00)	NOS2NOS1NOS3CYP2C19MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.