Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA known ✓ | P17252 | 12/20 | 0.98 |
| ▸ | PRKCG known ✓ | P05129 | 11/20 | 0.98 |
| ▸ | PRKCB known ✓ | P05771 | 11/20 | 0.98 |
| ▸ | PRKCE known ✓ | Q02156 | 11/20 | 0.98 |
| ▸ | PRKCH known ✓ | P24723 | 10/20 | 0.98 |
| ▸ | PRKCD known ✓ | Q05655 | 10/20 | 0.98 |
| ▸ | PRKCZ known ✓ | Q05513 | 7/20 | 0.98 |
| ▸ | SRC known ✓ | P12931 | 3/20 | 0.72 |
| ▸ | CDK4 known ✓ | P11802 | 1/20 | 0.66 |
| ▸ | MET known ✓ | P08581 | 1/20 | 0.62 |
| ▸ | PDGFRB known ✓ | P09619 | 1/20 | 0.62 |
| ▸ | KIT known ✓ | P10721 | 1/20 | 0.62 |
| ▸ | FGFR1 known ✓ | P11362 | 1/20 | 0.62 |
| ▸ | FLT4 known ✓ | P35916 | 1/20 | 0.62 |
| ▸ | FLT3 known ✓ | P36888 | 1/20 | 0.62 |
| ▸ | PRKCQ known ✓ | Q04759 | 1/20 | 0.62 |
| ▸ | CAMK2D | Q13557 | 10/20 | 0.98 |
| ▸ | CAMK2B | Q13554 | 8/20 | 0.98 |
| ▸ | CAMK2G | Q13555 | 8/20 | 0.98 |
| ▸ | CAMK2A | Q9UQM7 | 8/20 | 0.98 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3143669 | 0.99 | PRKCA (1.00) | PRKCAPRKCGPRKCBPRKCECAMK2D | |
| Hydrochloric Acid SCHEMBL3155547 | 0.89 | PRKCB (0.98) | PRKCAPRKCGPRKCBPRKCECAMK2D | |
| SCHEMBL3146547 | 0.87 | PRKCB (1.00) | PRKCAPRKCGPRKCBPRKCECAMK2D | |
| SCHEMBL3158797 | 0.84 | PRKCA (1.00) | PRKCAPRKCGPRKCBPRKCECAMK2D | |
| SCHEMBL6422277 | 0.84 | PRKCA (1.00) | PRKCAPRKCGPRKCBPRKCECAMK2D | |
| SCHEMBL3151388 | 0.83 | PRKCG (0.78) | PRKCAPRKCGPRKCBPRKCECAMK2D | |
| SCHEMBL27683415 | 0.82 | PRKCG (0.71) | PRKCAPRKCGPRKCBPRKCECAMK2D | |
| SCHEMBL6423238 | 0.82 | PRKCG (1.00) | PRKCAPRKCGPRKCBPRKCECAMK2D | |
| SCHEMBL30958440 | 0.82 | PRKCA (0.70) | PRKCAPRKCGPRKCBPRKCECAMK2D | |
| SCHEMBL30319849 | 0.81 | CCNE2 (1.00) | PRKCACDK2CCNE2CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4654966-A1 | METHODS AND COMPOSITIONS FOR TREATMENT OF OBESITY AND DISEASES ASSOCIATED WITH FAT CELL ENLARGEMENT | MELLICELL, INC. (US) | 2025-12-03 | — | — | EP | disclosed |
| WO-2024159211-A1 | METHODS AND COMPOSITIONS FOR TREATMENT OF OBESITY AND DISEASES ASSOCIATED WITH FAT CELL ENLARGEMENT | MELLICELL, INC. (US) | 2024-08-02 | — | — | WO | disclosed |