Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA known ✓ | P10253 | 3/20 | 0.55 |
| ▸ | ADRA2A known ✓ | P08913 | 6/20 | 0.50 |
| ▸ | ADRA2B known ✓ | P18089 | 3/20 | 0.50 |
| ▸ | ADRA2C known ✓ | P18825 | 3/20 | 0.50 |
| ▸ | HSP90AA1 known ✓ | P07900 | 1/20 | 0.50 |
| ▸ | HSP90AB1 known ✓ | P08238 | 1/20 | 0.50 |
| ▸ | EGFR known ✓ | P00533 | 1/20 | 0.45 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.43 |
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.41 |
| ▸ | NR3C1 known ✓ | P04150 | 1/20 | 0.41 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.41 |
| ▸ | ADRB1 known ✓ | P08588 | 1/20 | 0.41 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.41 |
| ▸ | ADRB3 known ✓ | P13945 | 1/20 | 0.41 |
| ▸ | DRD2 known ✓ | P14416 | 1/20 | 0.41 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.41 |
| ▸ | DRD1 known ✓ | P21728 | 1/20 | 0.41 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.41 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL440145 | 0.97 | MAPT (0.57) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| Bromide SCHEMBL4725114 | 0.95 | MAPT (0.55) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL16960488 | 0.91 | MAPT (0.52) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| Sulfuric Acid SCHEMBL9257267 | 0.87 | ALDH1A1 (0.61) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL9181167 | 0.87 | MAPT (0.56) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL13827339 | 0.85 | APP (0.62) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL10381752 | 0.85 | LTA4H (0.57) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL19272271 | 0.85 | ADRA2A (0.56) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL526383 | 0.84 | MAPT (0.58) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| Phenol SCHEMBL7546804 | 0.81 | LMNA (0.52) | MAPTALDH1A1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2809658-B1 | FUNGICIDAL PYRIMIDINE COMPOUNDS | BASF SE (DE) | 2015-09-30 | — | — | EP | disclosed |
| US-9055750-B2 | Fungicidal pyrimidine compounds | BASF SE (DE) | 2015-06-16 | — | — | US | disclosed |
| US-20150024936-A1 | Fungicidal Pyrimidine Compounds | BASF SE (DE) | 2015-01-22 | — | — | US | disclosed |
| EP-2809658-A1 | FUNGICIDAL PYRIMIDINE COMPOUNDS | BASF SE (DE) | 2014-12-10 | — | — | EP | disclosed |
| WO-2013113787-A1 | FUNGICIDAL PYRIMIDINE COMPOUNDS | BASF SE (DE) | 2013-08-08 | — | — | WO | disclosed |
| WO-2013113788-A1 | FUNGICIDAL PYRIMIDINE COMPOUNDS | BASF SE (DE) | 2013-08-08 | — | — | WO | disclosed |
| WO-2013113863-A1 | FUNGICIDAL PYRIMIDINE COMPOUNDS | BASF SE (DE) | 2013-08-08 | — | — | WO | disclosed |
| US-8298519-B2 | Hair treatment compositions incorporating hair substantive polymers | CONOPCO, INC. (US) | 2012-10-30 | — | — | US | disclosed |
| CN-102030676-A | Synthesis method of bezafibrate for regulating blood fat | HEFEI HUAFANG MEDICINE TECHNOLOGY CO LTD | 2011-04-27 | — | — | CN | disclosed |
| US-20100015077-A1 | Hair Treatment Compositions Incorporating Hair Substantive Polymers | CONOPCO, INC. D/B/A UNILEVER | 2010-01-21 | — | — | US | disclosed |
| EP-2056788-A1 | HAIR TREATMENT COMPOSITIONS INCORPORATING HAIR SUBSTANTIVE POLYMERS | Unilever PLC (GB) | 2009-05-13 | — | — | EP | disclosed |
| US-7393930-B2 | Modified protein adhesives and lignocellulosic composites made from the adhesives | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY (US) | 2008-07-01 | — | — | US | disclosed |
| WO-2008025671-A1 | HAIR TREATMENT COMPOSITIONS INCORPORATING HAIR SUBSTANTIVE POLYMERS | UNILEVER PLC (GB) | 2008-03-06 | — | — | WO | disclosed |
| US-20060156954-A1 | Modified protein adhesives and lignocellulosic composites made from the adhesives | STATE OF OR. ACTING BY & THROUGH THE OR. STATE BOARD OF HIGHER EDU. ON BEHALF OF OR. STATE UNIV. | 2006-07-20 | — | — | US | disclosed |
| US-7060798-B2 | Modified protein adhesives and lignocellulosic composites made from the adhesives | STATE OF OREGON ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY (US) | 2006-06-13 | — | — | US | disclosed |
| US-20040037906-A1 | Modified protein adhesives and lignocellulosic composites made from the adhesives | STATE OF OREGON ACTING BY AND THROUGH THE OREGON STATE | 2004-02-26 | — | — | US | disclosed |
| US-5430189-A | Process for preparing substituted and unsubstituted arylalkylamines | HOECHST CELANESE CORPORATION (US) | 1995-07-04 | — | — | US | disclosed |
| US-5319142-A | Process for preparing substituted and unsubstituted arylalkylamines | HOECHST CELANESE CORPORATION (US) | 1994-06-07 | — | — | US | disclosed |
| US-4121938-A | Photographic material containing TiO2, soluble Cu(II) salt, and soluble silver salt and the use thereof in physical development | FUJI PHOTO FILM CO., LTD. (JP) | 1978-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150024936-A1 | Fungicidal Pyrimidine Compounds | DPM1, DPYD, TYMP | GAA 394/4885ADRA2A 4722/4885ADRA2B 4505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.