SCHEMBL319016

SCHEMBL319016

O=C(Oc1c(F)c(F)cc(F)c1F)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39
CA4 P22748 2/20 0.39
CES2 O00748 2/20 0.37
CES1 P23141 2/20 0.37
MAPT P10636 2/20 0.36
KDM4E B2RXH2 2/20 0.36
ALDH1A1 P00352 1/20 0.36
HTT P42858 1/20 0.36
RIPK1 Q13546 4/20 0.33
MAPK1 P28482 1/20 0.32
NR3C1 P04150 1/20 0.30
CA12 O43570 1/20 0.30
CA7 P43166 1/20 0.30
CA13 Q8N1Q1 1/20 0.30
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18803184 0.83 ELANE (0.44) CA1CA2CA4CES2CES1
SCHEMBL40376 0.82 TSHR (0.35) CA1CA2NR3C1
SCHEMBL10181456 0.82 CES2 (0.42) CES2CES1RIPK1
SCHEMBL17552762 0.81 RIPK1 (0.46) CA1CA2CA4MAPTKDM4E
SCHEMBL19402718 0.81 RIPK1 (0.36) CA1CA2CA4CES2CES1
SCHEMBL10181736 0.79 CES2 (0.41) CA1CA2CA4CES2CES1
SCHEMBL10181554 0.79 CES2 (0.38) CES2CES1RIPK1
SCHEMBL17740107 0.78 CA1 (0.41) CA1CA2CA4CES2CES1
SCHEMBL24635135 0.78 ELANE (0.36) CA1CA2CA4CES2CES1
SCHEMBL18697369 0.78 CA1 (0.44) CA1CA2CA4CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 312 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1520177-B1 METHOD AND REAGENT FOR SPECIFICALLY IDENTIFYING AND QUANTIFYING ONE OR MORE PROTEINS IN A SAMPLE PROTEOME FACTORY AG (DE) 2014-05-07 EP claimed
US-20140017797-A1 PROTEIN AFFINITY TAG AND USES THEREOF De Staadt der Nederlanden, vert doorde minister van VWS (NL) 2014-01-16 US claimed
EP-2651961-A1 PROTEIN AFFINITY TAG AND USES THEREOF De Staat Der Nederlanden, Vert. Door De Minister Van VWS (NL) 2013-10-23 EP claimed
WO-2012081978-A1 PROTEIN AFFINITY TAG AND USES THEREOF DE STAAT DER NEDERLANDEN, VERT. DOOR DE MINISTER VAN VWS (NL) 2012-06-21 WO claimed
WO-2012034613-A3 REFRIGERATOR RED BULL GMBH (AT) 2012-05-10 WO claimed
EP-1329513-B1 Rapid quantitative analysis of proteins or protein function in complex mixtures UNIV WASHINGTON (US) 2011-12-07 EP claimed
US-20060246530-A1 Method and reagent for the specifically identifying and quantifying one or more proteins in a sample PROTEOME FACTORY AG (DE) 2006-11-02 US claimed
EP-1520177-A2 METHOD AND REAGENT FOR SPECIFICALLY IDENTIFYING AND QUANTIFYING ONE OR MORE PROTEINS IN A SAMPLE Proteome Factory AG (DE) 2005-04-06 EP claimed
US-6852544-B2 Rapid quantitative analysis of proteins or protein function in complex mixtures UNIVERSITY OF WASHINGTON (US) 2005-02-08 US claimed
WO-2004001420-A2 METHOD AND REAGENT FOR SPECIFICALLY IDENTIFYING AND QUANTIFYING ONE OR MORE PROTEINS IN A SAMPLE PROTEOME FACTORY AG (DE) 2003-12-31 WO claimed
US-6670194-B1 Mass spectrometry; screening for changes in the expression of enzymatic activity of specific proteins induced by absence, deficiency or excess of a given protein UNIVERSITY OF WASHINGTON 2003-12-30 US claimed
EP-1105517-B1 RAPID QUANTITATIVE ANALYSIS OF PROTEINS OR PROTEIN FUNCTION IN COMPLEX MIXTURES UNIV WASHINGTON (US) 2003-10-29 EP claimed
EP-1329513-A1 Rapid quantitative analysis of proteins or protein function in complex mixtures UNIVERSITY OF WASHINGTON (US) 2003-07-23 EP claimed
US-20030087322-A9 Rapid quantitative analysis of proteins or protein function in complex mixtures UNIVERSITY OF WASHINGTON 2003-05-08 US claimed
JP-2002523058-A 2002-07-30 JP claimed
US-20020076739-A1 Rapid quantitative analysis of proteins or protein function in complex mixtures UNIVERSITY OF WASHINGTON 2002-06-20 US claimed
EP-1105517-A4 RAPID QUANTITATIVE ANALYSIS OF PROTEINS OR PROTEIN FUNCTION IN COMPLEX MIXTURES UNIV WASHINGTON (US) 2001-09-19 EP claimed
EP-1105517-A1 RAPID QUANTITATIVE ANALYSIS OF PROTEINS OR PROTEIN FUNCTION IN COMPLEX MIXTURES UNIVERSITY OF WASHINGTON (US) 2001-06-13 EP claimed
WO-2000011208-A1 RAPID QUANTITATIVE ANALYSIS OF PROTEINS OR PROTEIN FUNCTION IN COMPLEX MIXTURES UNIVERSITY OF WASHINGTON (US) 2000-03-02 WO claimed
EP-4638745-A1 NOVEL FAS RNAI THERAPEUTICS AND USES THEREOF Eli Lilly and Company (US) 2025-10-29 EP disclosed
EP-3581195-B1 ANTIBODIES TO OLANZAPINE HAPTENS AND USE THEREOF JANSSEN PHARMACEUTICA NV (BE) 2025-10-01 EP disclosed
EP-3492473-B1 HAPTENS OF OLANZAPINE JANSSEN PHARMACEUTICA NV (BE) 2025-07-30 EP disclosed
EP-4444301-A1 PRODRUGS FOR COMPOUNDS SPECIFIC TO GRANZYME B AND USES THEREOF Cytosite Biopharma Inc. (US) 2024-10-16 EP disclosed
US-20240228785-A1 Fluorogenic pH-Sensitive Compounds and Their Methods of Use Life Technologies Corporation 2024-07-11 US disclosed
US-20240228785-A1 Fluorogenic pH-Sensitive Compounds and Their Methods of Use Life Technologies Corporation 2024-07-11 US disclosed
WO-2024137729-A1 NOVEL FAS RNAi THERAPEUTICS AND USES THEREOF ELI LILLY AND COMPANY (US) 2024-06-27 WO disclosed
EP-2888285-B1 ANTIBODIES TO ARIPIPRAZOLE HAPTENS AND USE THEREOF JANSSEN PHARMACEUTICA NV (BE) 2024-04-17 EP disclosed
CN-117858948-A Novel therapeutic agent delivery moieties and uses thereof 伊莱利利公司 2024-04-09 CN disclosed
CN-110054694-B Antibodies to aripiprazole hapten and uses thereof 詹森药业有限公司 2024-02-20 CN disclosed
US-20240010657-A1 BIOTIN DERIVATIVES Life Technologies Corporation 2024-01-11 US disclosed
EP-3556759-B1 HAPTENS OF PALIPERIDONE JANSSEN PHARMACEUTICA NV (BE) 2023-11-29 EP disclosed
US-11731982-B2 Biotin derivatives Life Technologies Corporation 2023-08-22 US disclosed
US-11731982-B2 Biotin derivatives Life Technologies Corporation 2023-08-22 US disclosed
US-11731982-B2 Biotin derivatives Life Technologies Corporation 2023-08-22 US disclosed
WO-2023108031-A1 PRODRUGS FOR COMPOUNDS SPECIFIC TO GRANZYME B AND USES THEREOF CYTOSITE BIOPHARMA INC. (US) 2023-06-15 WO disclosed
EP-2888284-B1 ANTIBODIES TO RISPERIDONE HAPTENS AND USE THEREOF JANSSEN PHARMACEUTICA NV (BE) 2022-07-06 EP disclosed
CN-109970637-B Aripiprazole hapten and application thereof in immunoassay 詹森药业有限公司 2022-04-19 CN disclosed
CN-108484496-B Aripiprazole hapten and application thereof in immunoassay 詹森药业有限公司 2022-03-22 CN disclosed
US-11226345-B2 Antibodies to olanzapine haptens and use thereof JANSSEN PHARMACEUTICA NV (BE) 2022-01-18 US disclosed
US-11225527-B2 Antibodies to paliperidone haptens and use thereof JANSSEN PHARMACEUTICA NV (BE) 2022-01-18 US disclosed
EP-3415516-B1 HAPTENS OF RISPERIDONE AND PALIPERIDONE JANSSEN PHARMACEUTICA NV (BE) 2021-12-15 EP disclosed
US-20210017294-A9 ANTIBODIES TO QUETIAPINE HAPTENS AND USE THEREOF JANSSEN PHARMACEUTICA NV (BE) 2021-01-21 US disclosed
US-20200399400-A1 ANTIBODIES TO RISPERIDONE HAPTENS AND USE THEREOF JANSSEN PHARMACEUTICA NV (BE) 2020-12-24 US disclosed
US-10793644-B2 Antibodies to risperidone haptens and use thereof JANSSEN PHARMACEUTICA NV (BE) 2020-10-06 US disclosed
EP-3305784-B1 HAPTENS OF QUETIAPINE FOR USE IN IMMUNOASSAYS JANSSEN PHARMACEUTICA NV (BE) 2020-08-12 EP disclosed
EP-3321254-B1 HAPTENS OF ARIPIPRAZOLE AND THEIR USE IN IMMUNOASSAYS JANSSEN PHARMACEUTICA NV (BE) 2020-08-12 EP disclosed
US-10712353-B2 Antibodies to olanzapine haptens and use thereof JANSSEN PHARMACEUTICA NV (BE) 2020-07-14 US disclosed
EP-3663317-A1 ANTIBODIES TO QUETIAPINE HAPTENS AND USE THEREOF Janssen Pharmaceutica NV (BE) 2020-06-10 EP disclosed
CN-107266432-B Quetiapine haptens for immunoassays 詹森药业有限公司 2020-05-12 CN disclosed
EP-3385284-B1 ANTIBODIES TO QUETIAPINE HAPTENS AND USE THEREOF JANSSEN PHARMACEUTICA NV (BE) 2020-02-26 EP disclosed
US-10570250-B2 Dibenzosilole monomers and polymers and methods for their preparation and use Life Technologies Corporation (US) 2020-02-25 US disclosed
US-20200040107-A1 ANTIBODIES TO QUETIAPINE HAPTENS AND USE THEREOF JANSSEN PHARMACEUTICA NV (BE) 2020-02-06 US disclosed
US-20190338047-A1 Antibodies to Paliperidone Haptens and Use Thereof JANSSEN PHARMACEUTICA NV (BE) 2019-11-07 US disclosed
US-10465013-B2 Antibodies to quetiapine haptens and use thereof JANSSEN PHARMACEUTICA NV (BE) 2019-11-05 US disclosed
US-20190331663-A1 Antibodies to Aripiprazole Haptens and Use Thereof JANSSEN PHARMACEUTICA NV (BE) 2019-10-31 US disclosed
US-20190322681-A1 Biotin Derivatives LIFE TECHNOLOGIES AS (NO) 2019-10-24 US disclosed
US-20190322681-A1 Biotin Derivatives LIFE TECHNOLOGIES AS (NO) 2019-10-24 US disclosed
EP-3556759-A1 HAPTENS OF PALIPERIDONE Janssen Pharmaceutica NV (BE) 2019-10-23 EP disclosed
US-10379105-B2 Antibodies to aripiprazole haptens and use thereof JANSSEN PHARMACEUTICA NV (BE) 2019-08-13 US disclosed
US-10370457-B2 Antibodies to paliperidone haptens and use thereof JANSSEN PHARMACEUTICA NV (BE) 2019-08-06 US disclosed
CN-110003201-A Paliperidone haptens 詹森药业有限公司 2019-07-12 CN disclosed
EP-3502693-A1 CELL TRACKING REAGENTS AND THEIR METHODS OF USE Life Technologies Corporation (US) 2019-06-26 EP disclosed
EP-2888258-B1 HAPTENS OF PALIPERIDONE JANSSEN PHARMACEUTICA NV (BE) 2019-06-05 EP disclosed
EP-3492473-A1 HAPTENS OF OLANZIPINE Janssen Pharmaceutica NV (BE) 2019-06-05 EP disclosed
EP-2887952-B1 ANTIBODIES TO OLANZAPINE HAPTENS AND USE THEREOF JANSSEN PHARMACEUTICA NV (BE) 2019-05-15 EP disclosed
US-10166296-B2 Haptens of aripiprazole JANSSEN PHARMACEUTICA NV (BE) 2019-01-01 US disclosed
EP-3415516-A1 HAPTENS OF RISPERIDONE AND PALIPERIDONE Janssen Pharmaceutica NV (BE) 2018-12-19 EP disclosed
US-20180355098-A1 DIBENZOSILOLE MONOMERS AND POLYMERS AND METHODS FOR THEIR PREPARATION AND USE Life Technologies Corporation 2018-12-13 US disclosed
EP-2888269-B1 HAPTENS OF OLANZAPINE JANSSEN PHARMACEUTICA NV (BE) 2018-10-24 EP disclosed
EP-3385284-A1 ANTIBODIES TO QUETIAPINE HAPTENS AND USE THEREOF Janssen Pharmaceutica NV (BE) 2018-10-10 EP disclosed
US-10087280-B2 Dibenzosilole monomers and polymers and methods for their preparation and use Life Technologies Corporation (US) 2018-10-02 US disclosed
US-20180149637-A1 ANTIBODIES TO ARIPIPRAZOLE HAPTENS AND USE THEREOF JANSSEN PHARMACEUTICA NV (BE) 2018-05-31 US disclosed
EP-3321254-A1 HAPTENS OF ARIPIPRAZOLE AND THEIR USE IN IMMUNOASSAYS Janssen Pharmaceutica NV (BE) 2018-05-16 EP disclosed
EP-2888263-B1 HAPTENS OF RISPERIDONE AND PALIPERIDONE JANSSEN PHARMACEUTICA NV (BE) 2018-05-09 EP disclosed
US-20180117169-A1 HAPTENS OF ARIPIPRAZOLE JANSSEN PHARMACEUTICA NV (BE) 2018-05-03 US disclosed
US-20180105606-A1 ANTIBODIES TO QUETIAPINE HAPTENS AND USE THEREOF JANSSEN PHARMACEUTICA NV (BE) 2018-04-19 US disclosed
EP-3305784-A1 HAPTENS OF QUETIAPINE FOR USE IN IMMUNOASSAYS Janssen Pharmaceutica NV (BE) 2018-04-11 EP disclosed
EP-2888286-B1 ANTIBODIES TO QUETIAPINE HAPTENS AND USE THEREOF JANSSEN PHARMACEUTICA NV (BE) 2018-02-21 EP disclosed
US-20180022827-A1 ANTIBODIES TO RISPERIDONE HAPTENS AND USE THEREOF JANSSEN PHARMACEUTICA NV (BE) 2018-01-25 US disclosed
EP-2633062-B1 BIOTIN DERIVATIVES LIFE TECHNOLOGIES CORP (US) 2017-12-27 EP disclosed
EP-2633062-B1 BIOTIN DERIVATIVES LIFE TECHNOLOGIES CORP (US) 2017-12-27 EP disclosed
US-9850318-B2 Antibodies to quetiapine haptens and use thereof JANSSEN PHARMACEUTICA NV (BE) 2017-12-26 US disclosed
EP-2888234-B1 HAPTENS OF ARIPIPRAZOLE AND THEIR USE IN IMMUNOASSAYS JANSSEN PHARMACEUTICA NV (BE) 2017-12-06 EP disclosed
US-20170343569-A1 ANTIBODIES TO OLANZAPINE HAPTENS AND USE THEREOF JANSSEN PHARMACEUTICA NV (BE) 2017-11-30 US disclosed
US-9795685-B2 Haptens of aripiprazole JANSSEN PHARMACEUTICA NV (BE) 2017-10-24 US disclosed
US-20170298147-A1 ANTIBODIES TO PALIPERIDONE HAPTENS AND USE THEREOF JANSSEN PHARMACEUTICA NV (BE) 2017-10-19 US disclosed
EP-3215515-A1 DIBENZOSILOLE MONOMERS AND POLYMERS AND METHODS FOR THEIR PREPARATION AND USE Life Technologies Corporation (US) 2017-09-13 EP disclosed
US-9751953-B2 Antibodies to risperidone haptens and use thereof JANSSEN PHARMACEUTICA NV (BE) 2017-09-05 US disclosed
US-20170247504-A1 DIBENZOSILOLE MONOMERS AND POLYMERS AND METHODS FOR THEIR PREPARATION AND USE Life Technologies Corporation 2017-08-31 US disclosed
US-20170240653-A1 ANTIBODIES TO OLANZAPINE HAPTENS AND USE THEREOF JANSSEN PHARMACEUTICA NV (BE) 2017-08-24 US disclosed
EP-2888257-B1 HAPTENS OF QUETIAPINE FOR USE IN IMMUNOASSAYS JANSSEN PHARMACEUTICA NV (BE) 2017-08-02 EP disclosed
US-20170204198-A1 Antibodies to Aripiprazole Haptens and Use Thereof JANSSEN PHARMACEUTICA NV (BE) 2017-07-20 US disclosed
US-20170174700-A1 Biotin Derivatives Life Technologies Corporation 2017-06-22 US disclosed
US-20170129968-A1 ANTIBODIES TO PALIPERIDONE HAPTENS AND USE THEREOF JANSSEN PHARMACEUTICA NV (BE) 2017-05-11 US disclosed
US-9611332-B2 Antibodies to aripiprazole haptens and use thereof JANSSEN PHARMACEUTICA NV (BE) 2017-04-04 US disclosed
EP-3143400-A1 CELL TRACKING REAGENTS AND THEIR METHODS OF USE Life Technologies Corporation (US) 2017-03-22 EP disclosed
US-20170072061-A1 HAPTENS OF ARIPIPRAZOLE JANSSEN PHARMACEUTICA NV (BE) 2017-03-16 US disclosed
US-20170044372-A1 CELL TRACKING REAGENTS AND THEIR METHODS OF USE Life Technologies Corporation 2017-02-16 US disclosed
US-9567346-B2 Biotin derivatives Life Technologies Corporation (US) 2017-02-14 US disclosed
US-9567346-B2 Biotin derivatives Life Technologies Corporation (US) 2017-02-14 US disclosed
US-9567346-B2 Biotin derivatives Life Technologies Corporation (US) 2017-02-14 US disclosed
US-9513284-B2 Pyrenyloxysulfonic acid fluorescent agents Life Technologies Corporation (US) 2016-12-06 US disclosed
US-20160346409-A1 TARGETED MOLECULAR IMAGING CONTRAST AGENTS UNIV MCMASTER (CA) 2016-12-01 US disclosed
US-9504682-B2 Haptens of aripiprazole JANSSEN PHARMACEUTICA NV (BE) 2016-11-29 US disclosed
US-9394354-B2 Haptens of paliperidone JANSSEN PHARMACEUTICA NV (BE) 2016-07-19 US disclosed
WO-2016073052-A1 DIBENZOSILOLE MONOMERS AND POLYMERS AND METHODS FOR THEIR PREPARATION AND USE Life Technologies Corporation (US) 2016-05-12 WO disclosed
US-9304126-B2 Haptens of quetiapine JANSSEN PHARMACEUTICA NV (BE) 2016-04-05 US disclosed
US-9303041-B2 Haptens of olanzapine JANSSEN PHARMACEUTICA NV (BE) 2016-04-05 US disclosed
WO-2015175873-A1 CELL TRACKING REAGENTS AND THEIR METHODS OF USE Life Technologies Corporation (US) 2015-11-19 WO disclosed
WO-2015117235-A1 TARGETED MOLECULAR IMAGING CONTRAST AGENTS MCMASTER UNIVERSITY (CA) 2015-08-13 WO disclosed
EP-2887952-A1 ANTIBODIES TO OLANZAPINE HAPTENS AND USE THEREOF ORTHO-CLINICAL DIAGNOSTICS, INC. (US) 2015-07-01 EP disclosed
EP-2888258-A1 HAPTENS OF PALIPERIDONE Janssen Pharmaceutica, N.V. (BE) 2015-07-01 EP disclosed
EP-2888284-A1 ANTIBODIES TO RISPERIDONE HAPTENS AND USE THEREOF ORTHO-CLINICAL DIAGNOSTICS, INC. (US) 2015-07-01 EP disclosed
EP-2888286-A1 ANTIBODIES TO QUETIAPINE HAPTENS AND USE THEREOF Ortho-Clinical Diagnostics Inc (US) 2015-07-01 EP disclosed
EP-2888285-A1 ANTIBODIES TO ARIPIPRAZOLE HAPTENS AND USE THEREOF ORTHO-CLINICAL DIAGNOSTICS, INC. (US) 2015-07-01 EP disclosed
EP-2888234-A1 HAPTENS OF ARIPIPRAZOLE AND THEIR USE IN IMMUNOASSAYS Janssen Pharmaceutica, N.V. (BE) 2015-07-01 EP disclosed
EP-2888287-A1 ANTIBODIES TO PALIPERIDONE HAPTENS AND USE THEREOF ORTHO-CLINICAL DIAGNOSTICS, INC. (US) 2015-07-01 EP disclosed
US-9012648-B2 Haptens of risperidone and paliperidone JANSSEN PHARMACEUTICA NV (BE) 2015-04-21 US disclosed
US-20140221616-A1 HAPTENS OF QUETIAPINE ORTHO-CLINICAL DIAGNOSTICS, INC. (US) 2014-08-07 US disclosed
US-20140213767-A1 HAPTENS OF PALIPERIDONE ORTHO-CLINICAL DIAGNOSTICS, INC. (US) 2014-07-31 US disclosed
US-20140213766-A1 HAPTENS OF OLANZIPINE ORTHO-CLINICAL DIAGNOSTICS, INC. (US) 2014-07-31 US disclosed
US-20140193926-A1 PYRENYLOXYSULFONIC ACID FLUORESCENT AGENTS Life Technologies Corporation (US) 2014-07-10 US disclosed
US-20140163206-A1 HAPTENS OF ARIPIPRAZOLE ORTHO-CLINICAL DIAGNOSTICS, INC. (US) 2014-06-12 US disclosed
US-20140155585-A1 HAPTENS OF RISPERIDONE AND PALIPERIDONE ORTHO-CLINICAL DIAGNOSTICS, INC. (US) 2014-06-05 US disclosed
EP-1520177-B1 METHOD AND REAGENT FOR SPECIFICALLY IDENTIFYING AND QUANTIFYING ONE OR MORE PROTEINS IN A SAMPLE PROTEOME FACTORY AG (DE) 2014-05-07 EP disclosed
US-20140057301-A1 Antibodies to Risperidone Haptens and Use Thereof JANSSEN PHARMACEUTICA NV (BE) 2014-02-27 US disclosed
US-20140057299-A1 Antibodies to Aripiprazole Haptens and Use Thereof JANSSEN PHARMACEUTICA NV (BE) 2014-02-27 US disclosed
WO-2014031635-A1 ANTIBODIES TO ARIPIPRAZOLE HAPTENS AND USE THEREOF ORTHO-CLINICAL DIAGNOSTICS, INC (US) 2014-02-27 WO disclosed
WO-2014031665-A1 ANTIBODIES TO QUETIAPINE HAPTENS AND USE THEREOF ORTHO-CLINICAL DIAGNOSTICS, INC (US) 2014-02-27 WO disclosed
US-20140057305-A1 Antibodies to Quetiapine Haptens and Use Thereof JANSSEN PHARMACEUTICA NV (BE) 2014-02-27 US disclosed
WO-2014031656-A1 ANTIBODIES TO OLANZAPINE HAPTENS AND USE THEREOF ORTHO-CLINICAL DIAGNOSTICS, INC (US) 2014-02-27 WO disclosed
US-20140057303-A1 Antibodies to Olanzapine Haptens and Use Thereof JANSSEN PHARMACEUTICA NV (BE) 2014-02-27 US disclosed
WO-2014031584-A1 HAPTENS OF ARIPIPRAZOLE AND THEIR USE IN IMMUNOASSAYS JANSSEN PHARMACEUTICA NV (BE) 2014-02-27 WO disclosed
US-20140057297-A1 Antibodies to Paliperidone Haptens and Use Thereof JANSSEN PHARMACEUTICA NV (BE) 2014-02-27 US disclosed
WO-2014031595-A1 HAPTENS OF PALIPERIDONE JANSSEN PHARMACEUTICA NV (BE) 2014-02-27 WO disclosed
WO-2014031645-A1 ANTIBODIES TO RISPERIDONE HAPTENS AND USE THEREOF ORTHO-CLINICAL DIAGNOSTICS, INC (US) 2014-02-27 WO disclosed
WO-2014031603-A1 ANTIBODIES TO PALIPERIDONE HAPTENS AND USE THEREOF ORTHO-CLINICAL DIAGNOSTICS, INC (US) 2014-02-27 WO disclosed
US-20140017797-A1 PROTEIN AFFINITY TAG AND USES THEREOF De Staadt der Nederlanden, vert doorde minister van VWS (NL) 2014-01-16 US disclosed
US-20140011255-A1 Biotin Derivatives Life Technologies Corporation (US) 2014-01-09 US disclosed
US-20140011255-A1 Biotin Derivatives Life Technologies Corporation (US) 2014-01-09 US disclosed
US-20140011255-A1 Biotin Derivatives Life Technologies Corporation (US) 2014-01-09 US disclosed
US-8614294-B2 Pyrenyloxysulfonic acid fluorescent agents Life Technologies Corporation (US) 2013-12-24 US disclosed
EP-2651961-A1 PROTEIN AFFINITY TAG AND USES THEREOF De Staat Der Nederlanden, Vert. Door De Minister Van VWS (NL) 2013-10-23 EP disclosed
EP-1684810-B1 Polybiotin compounds for magnetic resonance imaging and drug delivery GEN HOSPITAL CORP (US) 2013-09-25 EP disclosed
CN-103298949-A Biotin derivatives LIFE TECHNOLOGIES CORP 2013-09-11 CN disclosed
EP-2633062-A1 BIOTIN DERIVATIVES Life Technologies Corporation (US) 2013-09-04 EP disclosed
US-8465921-B2 Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders ELITECH HOLDING B.V. (NL) 2013-06-18 US disclosed
US-8435800-B2 Activated labeling reagents and methods for preparing and using the same BIOSIGHT LTD. (IL) 2013-05-07 US disclosed
US-20130079497-A1 PYRENYLOXYSULFONIC ACID FLUORESCENT AGENTS Life Technologies Corporation (US) 2013-03-28 US disclosed
US-8268886-B2 Pyrenyloxysulfonic acid fluorescent agents Life Technologies Corporation (US) 2012-09-18 US disclosed
WO-2012081978-A1 PROTEIN AFFINITY TAG AND USES THEREOF DE STAAT DER NEDERLANDEN, VERT. DOOR DE MINISTER VAN VWS (NL) 2012-06-21 WO disclosed
WO-2012034613-A3 REFRIGERATOR RED BULL GMBH (AT) 2012-05-10 WO disclosed
WO-2012058635-A1 BIOTIN DERIVATIVES Life Technologies Corporation (US) 2012-05-03 WO disclosed
WO-2012058635-A1 BIOTIN DERIVATIVES Life Technologies Corporation (US) 2012-05-03 WO disclosed
US-8124364-B2 Biotin derivatives GLYCOREX TRANSPLANTATION AB (SE) 2012-02-28 US disclosed
US-8124364-B2 Biotin derivatives GLYCOREX TRANSPLANTATION AB (SE) 2012-02-28 US disclosed
US-8124364-B2 Biotin derivatives GLYCOREX TRANSPLANTATION AB (SE) 2012-02-28 US disclosed
US-20120045848-A1 PYRENYLOXYSULFONIC ACID FLUORESCENT AGENTS Life Technologies Corporation (US) 2012-02-23 US disclosed
US-8097463-B2 Use of arylboronic acids in protein labelling KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2012-01-17 US disclosed
US-8092782-B2 Polybiotin compounds of magnetic resonance imaging and drug delivery THE GENERAL HOSPITAL CORPORATION (US) 2012-01-10 US disclosed
EP-1329513-B1 Rapid quantitative analysis of proteins or protein function in complex mixtures UNIV WASHINGTON (US) 2011-12-07 EP disclosed
US-20110275070-A1 HYBRIDIZATION AND MISMATCH DISCRIMINATION USING OLIGONUCLEOTIDES CONJUGATED TO MINOR GROOVE BINDERS EPOCH PHARMACEUTICALS, INC. 2011-11-10 US disclosed
US-8039642-B2 Pyrenyloxysulfonic acid fluorescent agents Life Technologies Corporation (US) 2011-10-18 US disclosed
US-20110217727-A1 METHOD FOR PATTERNING MAGNETIC MATERIALS IN LIVE CELL, METHOD FOR IMAGING PATTERN OF MAGNETIC MATERIALS, AND APPARATUS USED FOR SAME MEDISCOV INC. (KR) 2011-09-08 US disclosed
CN-101914099-A Covalently linked oligonucleotide minor groove binder conjugates EPOCH BIOSCIENCES INC 2010-12-15 CN disclosed
US-7794945-B2 Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders ELITECH HOLDING B.V. (NL) 2010-09-14 US disclosed
US-20100167262-A1 METHOD AND REAGENT FOR THE SPECIFIC IDENTIFICATION AND QUANTIFICATION OF ONE OR MORE PROTEINS IN A SAMPLE USING IN PARTICULAR INDUCTIVELY COUPLED PLASMA-MASS SPECTROMETRY PROTEOME FACTORY AG (DE) 2010-07-01 US disclosed
EP-1289563-B1 METHOD FOR CONDITIONING AN AVIDIN OR STREPTAVIDIN COLUMN MATRIX IN AN EXTRACORPOREAL DEVICE MITRA MEDICAL TECHNOLOGY AB (SE) 2010-06-02 EP disclosed
US-20100068819-A1 COMPOUNDS AND METHODS FOR DOUBLE LABELLING OF POLYPEPTIDES TO ALLOW MULTIPLEXING IN MASS SPECTROMETRIC ANALYSIS KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2010-03-18 US disclosed
US-20100041162-A1 USE OF ARYLBORONIC ACIDS IN PROTEIN LABELLING KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2010-02-18 US disclosed
EP-1105517-B2 RAPID QUANTITATIVE ANALYSIS OF PROTEINS OR PROTEIN FUNCTION IN COMPLEX MIXTURES UNIV WASHINGTON (US) 2009-09-30 EP disclosed
US-20090203879-A1 ACTIVATED LABELING REAGENTS AND METHODS FOR PREPARING AND USING THE SAME BIOSIGHT LTD 2009-08-13 US disclosed
EP-2086984-A1 USE OF ARYLBORONIC ACIDS IN PROTEIN LABELLING Philips Intellectual Property & Standards GmbH (DE) 2009-08-12 EP disclosed
EP-2087357-A1 COMPOUNDS AND METHODS FOR DOUBLE LABELLING OF POLYPEPTIDES TO ALLOW MULTIPLEXING IN MASS SPECTROMETRIC ANALYSIS Koninklijke Philips Electronics N.V. (NL) 2009-08-12 EP disclosed
EP-1144429-B1 HYBRIDIZATION AND MISMATCH DISCRIMINATION USING OLIGONUCLEOTIDES CONJUGATED TO MINOR GROOVE BINDERS EPOCH BIOSCIENCES INC (US) 2009-07-15 EP disclosed
US-7556923-B1 Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders EPOCH BIOSCIENCES, INC. (US) 2009-07-07 US disclosed
EP-1814908-A4 ACTIVATED LABELING REAGENTS AND METHODS FOR PREPARING AND USING THE SAME BIOSIGHT LTD (IL) 2009-07-01 EP disclosed
US-7544518-B2 Rapid quantitative analysis of proteins or protein function in complex mixtures UNIVERSITY OF WASHINGTON (US) 2009-06-09 US disclosed
US-7544518-B2 Rapid quantitative analysis of proteins or protein function in complex mixtures UNIVERSITY OF WASHINGTON (US) 2009-06-09 US disclosed
US-7544518-B2 Rapid quantitative analysis of proteins or protein function in complex mixtures UNIVERSITY OF WASHINGTON (US) 2009-06-09 US disclosed
EP-1684810-A4 POLYBIOTIN COMPOUNDS FOR MAGNETIC RESONANCE IMAGINING AND DRUG DELIVERY GEN HOSPITAL CORP (US) 2009-05-27 EP disclosed
US-20090053742-A1 Capture and release based isotope tagged peptides and methods for using the same PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2009-02-26 US disclosed
US-20090048427-A1 HYBRIDIZATION AND MISMATCH DISCRIMINATION USING OLIGONUCLEOTIDES CONJUGATED TO MINOR GROOVE BINDERS EPOCH BIOSCIENCES, INC. (US) 2009-02-19 US disclosed
US-20090010845-A1 Polybiotin Compounds of Magnetic Resonance Imaging and Drug Delivery THE GENERAL HOSPITAL CORPORATION (US) 2009-01-08 US disclosed
EP-2008109-A1 METHOD AND REAGENT FOR THE SPECIFIC IDENTIFICATION AND QUANTIFICATION OF ONE OR MORE PROTEINS IN A SAMPLE USING INDUCTIVELY COUPLED PLASMA-MASS SPECTROMETRY Proteome Factory AG (DE) 2008-12-31 EP disclosed
US-7438893-B2 Polybiotin compounds for magnetic resonance imaging and drug delivery MASSACHUSETTS GENERAL HOSPITAL (US) 2008-10-21 US disclosed
US-7425451-B2 Triazine derivatives as universal peptide isotope tag reagents (U-PIT) AGILENT TECHNOLOGIES, INC. (US) 2008-09-16 US disclosed
WO-2008056290-A9 USE OF ARYLBORONIC ACIDS IN PROTEIN LABELLING PHILIPS INTELLECTUAL PROPERTY (DE) 2008-09-12 WO disclosed
EP-1631553-A4 CAPTURE AND RELEASE BASED ISOTOPE TAGGED PEPTIDES AND METHODS FOR USING THE SAME HARVARD COLLEGE (US) 2008-09-10 EP disclosed
WO-2008056290-A1 USE OF ARYLBORONIC ACIDS IN PROTEIN LABELLING PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH (DE) 2008-05-15 WO disclosed
EP-1921081-A1 Use of arylboronic acids in protein labelling Koninklijke Philips Electronics N.V. (NL) 2008-05-14 EP disclosed
WO-2008053399-A1 COMPOUNDS AND METHODS FOR DOUBLE LABELLING OF POLYPEPTIDES TO ALLOW MULTIPLEXING IN MASS SPECTROMETRIC ANALYSIS KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2008-05-08 WO disclosed
EP-1918714-A1 Compounds and methods for double labelling of polypeptides to allow multiplexing in mass spectrometric analysis Koninklijke Philips Electronics N.V. (NL) 2008-05-07 EP disclosed
EP-1916526-A1 Method for diagnostic and therapeutic target discovery by combining isotopic and isobaric labels Koninklijke Philips Electronics N.V. (NL) 2008-04-30 EP disclosed
US-20080081343-A1 Differential labeling for quantitative analysis of complex protein mixtures SYNGENTA PARTICIPATIONS AG (CH) 2008-04-03 US disclosed
US-7332613-B2 Capture and release based isotope tagged peptides and methods for using the same PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2008-02-19 US disclosed
US-20080032379-A1 PYRENYLOXYSULFONIC ACID FLURESCENT AGENTS INVITROGEN CORPORATION (US) 2008-02-07 US disclosed
EP-0819133-B1 COVALENTLY LINKED OLIGONUCLEOTIDE MINOR GROOVE BINDER CONJUGATES EPOCH BIOSCIENCES INC (US) 2008-01-02 EP disclosed
US-7297495-B2 Hybridization-triggered fluorescent detection of nucleic acids EPOCH BIOSCIENCES, INC. (US) 2007-11-20 US disclosed
WO-2007118712-A1 METHOD AND REAGENT FOR THE SPECIFIC IDENTIFICATION AND QUANTIFICATION OF ONE OR MORE PROTEINS IN A SAMPLE USING INDUCTIVELY COUPLED PLASMA-MASS SPECTROMETRY PROTEOME FACTORY AG (DE) 2007-10-25 WO disclosed
EP-1814908-A1 ACTIVATED LABELING REAGENTS AND METHODS FOR PREPARING AND USING THE SAME Biosight Ltd. (IL) 2007-08-08 EP disclosed
US-20070166723-A1 Hybridization-triggered fluorescent detection of nucleic acids EPOCH BIOSCIENCES INC. (US) 2007-07-19 US disclosed
US-7175986-B2 Methods and reagents for differential proteomic analysis PROTEOMYX INC. (US) 2007-02-13 US disclosed
US-20070031973-A1 Triazine derivatives as universal peptide isotope tag reagents (U-PIT) ROBOTTI KARLA M 2007-02-08 US disclosed
US-7166436-B2 Differential labeling for quantitative analysis of complex protein mixtures SYNGENTA PARTICIPATIONS, AG (CH) 2007-01-23 US disclosed
EP-1392848-B1 PROCESS FOR ANALYZING PROTEIN SAMPLES PERSEPTIVE BIOSYSTEMS INC (US) 2007-01-03 EP disclosed
US-7141676-B1 Water soluble multi-biotin-containing compounds UNIVERSITY OF WASHINGTON (US) 2006-11-28 US disclosed
US-20060246530-A1 Method and reagent for the specifically identifying and quantifying one or more proteins in a sample PROTEOME FACTORY AG (DE) 2006-11-02 US disclosed
US-20060228325-A1 Water soluble multi-biotin-containing compounds WILBUR D S 2006-10-12 US disclosed
EP-1684810-A1 POLYBIOTIN COMPOUNDS FOR MAGNETIC RESONANCE IMAGINING AND DRUG DELIVERY THE GENERAL HOSPITAL CORPORATION (US) 2006-08-02 EP disclosed
US-7052915-B2 Useful for the detection of phosphoproteins; amidating carboxy groups and forming phosphoramidates with phosphate groups, selectively deprotecting the phosphoramide group and reacting free phosphate groups UNIVERSITY OF WASHINGTON (US) 2006-05-30 US disclosed
WO-2006054310-A1 ACTIVATED LABELING REAGENTS AND METHODS FOR PREPARING AND USING THE SAME BIOSIGHT LTD. (IL) 2006-05-26 WO disclosed
US-7045296-B2 Process for analyzing protein samples APPLERA CORPORATION (US) 2006-05-16 US disclosed
EP-1428019-A4 SYSTEM AND METHOD OF DETERMINING PROTEOMIC DIFFERENCES SYNGENTA PARTICIPATIONS AG (CH) 2006-04-26 EP disclosed
EP-1631553-A2 CAPTURE AND RELEASE BASED ISOTOPE TAGGED PEPTIDES AND METHODS FOR USING THE SAME PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2006-03-08 EP disclosed
US-20060004525-A1 System and method of determining proteomic differences SYNGENTA PARTICIPATIONS AG 2006-01-05 US disclosed
US-6969757-B2 Differential labeling for quantitative analysis of complex protein mixtures SYNGENTA PARTICIPATIONS AG (CH) 2005-11-29 US disclosed
US-20050250957-A1 Compounds containing thiosulfate moieties MOLECULAR PROBES, INC 2005-11-10 US disclosed
US-20050233399-A1 Rapid quantitative analysis of proteins or protein function in complex mixtures UNIVERSITY OF WASHINGTON 2005-10-20 US disclosed
EP-1456227-B1 NON-AFFINITY BASED ISOTOPE TAGGED PEPTIDES AND METHODS FOR USING THE SAME HARVARD COLLEGE (US) 2005-10-05 EP disclosed
US-6951930-B2 Hybridization-triggered fluorescent detection of nucleic acids EPOCH BIOSCIENCES, INC. (US) 2005-10-04 US disclosed
WO-2005042559-A9 CAPTURE AND RELEASE BASED ISOTOPE TAGGED PEPTIDES AND METHODS FOR USING THE SAME HARVARD COLLEGE (US) 2005-08-18 WO disclosed
CN-1644585-A Covalently linked oligonucleotide minor grove binder conjugates EPOCH PHARMACEUTICALS INC (US) 2005-07-27 CN disclosed
WO-2005064336-A1 PYRENYLOXYSULFONIC ACID FLUORESCENT AGENTS MOLECULAR PROBES, INC. (US) 2005-07-14 WO disclosed
US-20050136008-A1 Polybiotin compounds for magnetic resonance imaging and drug delivery MASSACHUSETTS GENERAL HOSPITAL (US) 2005-06-23 US disclosed
EP-1392848-A4 PROCESS FOR ANALYZING PROTEIN SAMPLES PERSEPTIVE BIOSYSTEMS INC (US) 2005-06-22 EP disclosed
US-20050123935-A1 Pyrenyloxysulfonic acid fluorescent agents MOLECULAR PROBES, INC. 2005-06-09 US disclosed
WO-2005047242-A2 COMPOUNDS CONTAINING THIOSULFATE MOIETIES MOLECULAR PROBES, INC. (US) 2005-05-26 WO disclosed
WO-2005042559-A2 CAPTURE AND RELEASE BASED ISOTOPE TAGGED PEPTIDES AND METHODS FOR USING THE SAME PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2005-05-12 WO disclosed
EP-1525483-A2 DIFFERENTIAL LABELING FOR QUANTITATIVE ANALYSIS OF COMPLEX PROTEIN MIXTURES BY TRIFUNCTIONAL SYNTHETIC PEPTIDE BASED REAGENTS WITH IODACETAMIDO GROUPS Syngenta Participations AG (CH) 2005-04-27 EP disclosed
US-6884584-B2 Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders EPOCH BIOSCIENCES, INC. (US) 2005-04-26 US disclosed
WO-2005032598-A1 POLYBIOTIN COMPOUNDS FOR MAGNETIC RESONANCE IMAGINING AND DRUG DELIVERY THE GENERAL HOSPITAL CORPORATION (US) 2005-04-14 WO disclosed
US-20050074794-A1 Methods and reagents for differential proteomic analysis TRAN NATHANIEL TUE (US) 2005-04-07 US disclosed
EP-1520177-A2 METHOD AND REAGENT FOR SPECIFICALLY IDENTIFYING AND QUANTIFYING ONE OR MORE PROTEINS IN A SAMPLE Proteome Factory AG (DE) 2005-04-06 EP disclosed
US-20050064463-A1 Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders DRUG ROYALTY LP1 (CA) 2005-03-24 US disclosed
EP-1346229-B1 INVERSE LABELING METHOD FOR THE RAPID IDENTIFICATION OF MARKER/TARGET PROTEINS NOVARTIS AG (CH) 2005-03-16 EP disclosed
US-6852544-B2 Rapid quantitative analysis of proteins or protein function in complex mixtures UNIVERSITY OF WASHINGTON (US) 2005-02-08 US disclosed
EP-1295123-A4 SELECTIVE LABELING AND ISOLATION OF PHOSPHOPEPTIDES AND APPLICATIONS TO PROTEOME ANALYSIS UNIV WASHINGTON (US) 2005-02-02 EP disclosed
CN-1187363-C Covalently bound oligonucleotide minor groove binder conjugates IBORCH PHARMACEUTICAL CORP (US) 2005-02-02 CN disclosed
US-20040259164-A1 Capture and release based isotope tagged peptides and methods for using the same PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2004-12-23 US disclosed
EP-1456227-A4 NON-AFFINITY BASED ISOTOPE TAGGED PEPTIDES AND METHODS FOR USING THE SAME HARVARD COLLEGE (US) 2004-12-15 EP disclosed
US-20040235186-A1 Non-affinity based isotope tagged peptides and methods for using the same PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2004-11-25 US disclosed
EP-1456227-A2 NON-AFFINITY BASED ISOTOPE TAGGED PEPTIDES AND METHODS FOR USING THE SAME PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2004-09-15 EP disclosed
WO-2002059144-A9 DIFFERENTIAL LABELING FOR QUANTITATIVE ANALYSIS OF COMPLEX PROTEIN MIXTURES SYNGENTA PARTICIPATIONS AG (US) 2004-08-12 WO disclosed
US-20040115821-A1 Triazine derivatives as universal peptide isotope tag reagents (U-PIT) AGILENT TECHNOLOGIES, INC. 2004-06-17 US disclosed
EP-1429147-A1 Universal reagent for isotopically tagging peptides Agilent Technologies, Inc. (US) 2004-06-16 EP disclosed
EP-1428019-A2 SYSTEM AND METHOD OF DETERMINING PROTEOMIC DIFFERENCES Syngenta Participations AG (CH) 2004-06-16 EP disclosed
US-20040106150-A1 Inverse labeling method for the rapid identification of marker/target proteins WANG YINGQI KAREN (US) 2004-06-03 US disclosed
WO-2003006951-A9 SYSTEM AND METHOD OF DETERMINING PROTEOMIC DIFFERENCES SYNGENTA PARTICIPATIONS AG (CH) 2004-05-13 WO disclosed
US-20040058322-A1 Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders EPOCH PHARMACEUTICALS, INC. (US) 2004-03-25 US disclosed
US-20040052784-A1 Biotin derivatives GLYCOREX TRANSPLANTATION AB (SE) 2004-03-18 US disclosed
EP-1392848-A2 PROCESS FOR ANALYZING PROTEIN SAMPLES PerSeptive Biosystems, Inc. (US) 2004-03-03 EP disclosed
WO-2004013636-A2 DIFFERENTIAL LABELING FOR QUANTITATIVE ANALYSIS OF COMPLEX PROTEIN MIXTURES BY TRIFUNCTIONAL SYNTHETIC PEPTIDE BASED REAGENTS WITH IODOACETAMIDO GROUPS SYNGENTA PARTICIPATIONS AG (CH) 2004-02-12 WO disclosed
WO-2004001420-A2 METHOD AND REAGENT FOR SPECIFICALLY IDENTIFYING AND QUANTIFYING ONE OR MORE PROTEINS IN A SAMPLE PROTEOME FACTORY AG (DE) 2003-12-31 WO disclosed
US-6670194-B1 Mass spectrometry; screening for changes in the expression of enzymatic activity of specific proteins induced by absence, deficiency or excess of a given protein UNIVERSITY OF WASHINGTON 2003-12-30 US disclosed
EP-1105517-B1 RAPID QUANTITATIVE ANALYSIS OF PROTEINS OR PROTEIN FUNCTION IN COMPLEX MIXTURES UNIV WASHINGTON (US) 2003-10-29 EP disclosed
EP-1346229-A2 INVERSE LABELING METHOD FOR THE RAPID IDENTIFICATION OF MARKER/TARGET PROTEINS Novartis AG (CH) 2003-09-24 EP disclosed
EP-1329513-A1 Rapid quantitative analysis of proteins or protein function in complex mixtures UNIVERSITY OF WASHINGTON (US) 2003-07-23 EP disclosed
US-20030113765-A1 Hybridization-triggered fluorescent detection of nucleic acids EPOCH BIOSCIENCES, INC. (US) 2003-06-19 US disclosed
US-20030087329-A1 Differential labeling for quantitative analysis of complex protein mixtures SYNGENTA PARTICIPATIONS AG (CH) 2003-05-08 US disclosed
US-20030087322-A9 Rapid quantitative analysis of proteins or protein function in complex mixtures UNIVERSITY OF WASHINGTON 2003-05-08 US disclosed
US-20030082522-A1 Differential labeling for quantitative analysis of complex protein mixtures SYNGENTA PARTICIPATIONS AG (CH) 2003-05-01 US disclosed
US-20030068825-A1 System and method of determining proteomic differences SYNGENTA PARTICIPATIONS AG (CH) 2003-04-10 US disclosed
EP-1295123-A1 SELECTIVE LABELING AND ISOLATION OF PHOSPHOPEPTIDES AND APPLICATIONS TO PROTEOME ANALYSIS UNIVERSITY OF WASHINGTON (US) 2003-03-26 EP disclosed
EP-1289563-A2 BIOTIN DERIVATIVES Mitra Medical Technology AB (SE) 2003-03-12 EP disclosed
WO-2003008547-A2 NON-AFFINITY BASED ISOTOPE TAGGED PEPTIDES AND METHODS FOR USING THE SAME PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2003-01-30 WO disclosed
WO-2003006951-A2 SYSTEM AND METHOD OF DETERMINING PROTEOMIC DIFFERENCES SYNGENTA PARTICIPATIONS AG (CH) 2003-01-23 WO disclosed
US-20020192720-A1 Process for analyzing protein samples APPLIED BIOSYSTEMS, LLC 2002-12-19 US disclosed
US-6492346-B1 Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders EPOCH PHARMACEUTICALS, INC. 2002-12-10 US disclosed
US-6486308-B2 NUCLEOTIDE SEQUENCE BINDING PARTICLES; FOR USE AS THERAPEUTIC AND DIAGNOSTIC TOOLS EPOCH BIOSCIENCES, INC. 2002-11-26 US disclosed
WO-2002090929-A2 PROCESS FOR ANALYZING PROTEIN SAMPLES PERSEPTIVE BIOSYSTEMS, INC. (US) 2002-11-14 WO disclosed
US-20020159994-A1 Biotin derivatives GLYCOREX TRANSPLANTATION AB (SE) 2002-10-31 US disclosed
US-6472153-B1 COVALENTLY BOUND OLIGONUCLEOTIDE/MINOR GROOVE BINDER/LATENT FLUOROPHORE COMBINATION EPOCH BIOSCIENCES, INC. 2002-10-29 US disclosed
EP-1144429-A3 HYBRIDIZATION AND MISMATCH DISCRIMINATION USING OLIGONUCLEOTIDES CONJUGATED TO MINOR GROOVE BINDERS Epoch Pharmaceuticals, Inc. (US) 2002-09-11 EP disclosed
WO-2002059144-A2 DIFFERENTIAL LABELING FOR QUANTITATIVE ANALYSIS OF COMPLEX PROTEIN MIXTURES SYNGENTA PARTICIPATION AG (US) 2002-08-01 WO disclosed
US-6426408-B1 PLURALITY OF NUCLEOTIDE UNITS WITH LINKING GROUP EPOCH BIOSCIENCES, INC. 2002-07-30 US disclosed
EP-1224332-A1 HYBRIDIZATION-TRIGGERED FLUORESCENT DETECTION OF NUCLEIC ACIDS Epoch Biosciences, Inc. (US) 2002-07-24 EP disclosed
US-20020090652-A1 Inverse labeling method for the rapid identification of marker/target proteins FU EMIL WEI-MING (US) 2002-07-11 US disclosed
WO-2002052271-A2 INVERSE LABELING METHOD FOR THE RAPID IDENTIFICATION OF MARKER/TARGET PROTEINS NOVARTIS AG (CH) 2002-07-04 WO disclosed
US-20020076739-A1 Rapid quantitative analysis of proteins or protein function in complex mixtures UNIVERSITY OF WASHINGTON 2002-06-20 US disclosed
US-20020052482-A1 Covalently linked oligonucleotide minor grove binder conjugates MICROPROBE 2002-05-02 US disclosed
US-20020049307-A1 Selective labeling and isolation of phosphopeptides and applications to proteome analysis WASHINGTON, UNIVERSITY OF 2002-04-25 US disclosed
WO-2001095857-A2 REUSABLE EXTRACORPOREAL COLUMS LOADED WITH LIGAND-DIBIOTIN CONJUGATES MITRA MEDICAL TECHNOLOGY AB (SE) 2001-12-20 WO disclosed
WO-2001096869-A1 SELECTIVE LABELING AND ISOLATION OF PHOSPHOPEPTIDES AND APPLICATIONS TO PROTEOME ANALYSIS UNIVERSITY OF WASHINGTON (US) 2001-12-20 WO disclosed
US-6312953-B1 MODIFIED OLIGONUCLEOTIDE COMPLEMENTARY TO A TARGET SEQUENCE AND HAVING AT LEAST TWO CROSSLINKING AGENTS COVALENTLY ATTATCHED; GENE EXPRESSION INHIBITION; DNA SEQUENCING; GENETIC MAPPING EPOCH PHARMACEUTICALS, INC. 2001-11-06 US disclosed
US-6312894-B1 HYBRIDIZATION OF OLIGONUCLEOTIDES AND MINOR GROOVE BINDER COMBINATION; WHERE THE MINOR GROOVE BINDER BINDS IN A NON-INTERCALATING MANNER WITH A HIGHER ASSOCIATION CONSTANT EPOCH PHARMACEUTICALS, INC. 2001-11-06 US disclosed
EP-1144429-A2 HYBRIDIZATION AND MISMATCH DISCRIMINATION USING OLIGONUCLEOTIDES CONJUGATED TO MINOR GROOVE BINDERS Epoch Pharmaceuticals, Inc. (US) 2001-10-17 EP disclosed
WO-2001031063-A1 HYBRIDIZATION-TRIGGERED FLUORESCENT DETECTION OF NUCLEIC ACIDS EPOCH BIOSCIENCES, INC. (US) 2001-05-03 WO disclosed
US-6143877-A FORMING A TRIPLEX BY CONTACTING DUPLEX NUCLEIC ACID HAVING A TARGET SEQUENCE OF PURINE BASES WITH A OLIGONUCLEOTIDE HAVING AT LEAST ONE GUANINE BASE REPLACED BY 6-AMINO-1H-PYRAZOLO(3,4-D)PYRIMIDIN-4(5H)-ONE EPOCH PHARMACEUTICALS, INC. (US) 2000-11-07 US disclosed
US-6084102-A THE OLIGONUCLEOTIDE IS COMPLEMENTARY TO A TARGET SEQUENCE OF SINGLE STRANDED OR DOUBLE STRANDED DNA, RNA OR HYBRIDS AND, WHEN USED AS A PROBE, BINDS MORE STRONGLY BECAUSE OF THE BOUND MINOR GROVE BINDER; MEDICAL DIAGNOSIS; ANTISENSE THERAPY EPOCH PHARMACEUTICALS, INC. (US) 2000-07-04 US disclosed
US-6072046-A SELECTIVELY FORM TRIPLEXES WITH A COMPLEMENTARY TARGET SEQUENCE IN DOUBLE-STRANDED DNA AND EFFICIENTLY CROSSLINK WITH BOTH STRANDS; THERAPEUTICS, DIAGNOSTICS, AND GENETIC PROBES EPOCH PHARMACEUTICALS, INC. (US) 2000-06-06 US disclosed
WO-2000012523-A1 DIAZIRIDINYL-ARYL AND BIS-[DI(CHLOROETHYL)AMINO]-ARYL OLIGONUCLEOTIDE CONJUGATES AND REAGENTS FOR MAKING THE SAME EPOCH PHARMACEUTICALS, INC. (US) 2000-03-09 WO disclosed
WO-1999051621-A2 HYBRIDIZATION AND MISMATCH DISCRIMINATION USING OLIGONUCLEOTIDES CONJUGATED TO MINOR GROOVE BINDERS EPOCH PHARMACEUTICALS, INC. (US) 1999-10-14 WO disclosed
US-5912340-A FORMING STABLE HYBRID WITH DNA, RNA EPOCH PHARMACEUTICALS, INC. (US) 1999-06-15 US disclosed
US-5849482-A Crosslinking oligonucleotides EPOCH PHARMACEUTICALS, INC. (US) 1998-12-15 US disclosed
WO-1998049180-A1 TRIPLEX FORMING OLIGONUCLEOTIDES INCLUDING PYRAZOLO(3,4-D)PYRIMIDINE BASES EPOCH PHARMACEUTICALS, INC. (US) 1998-11-05 WO disclosed
US-5801155-A Covalently linked oligonucleotide minor grove binder conjugates EPOCH PHARMACEUTICALS, INC. (US) 1998-09-01 US disclosed
CN-1186496-A Covalently bound oligonucleotide minor groove binder conjugates IBORCH PHARMACEUTICAL CORP (US) 1998-07-01 CN disclosed
EP-0842186-A1 CROSS-LINKING OLIGONUCLEOTIDES MICROPROBE CORPORATION (US) 1998-05-20 EP disclosed
EP-0819133-A2 COVALENTLY LINKED OLIGONUCLEOTIDE MINOR GROOVE BINDER CONJUGATES EPOCH PHARMACEUTICALS, INC. (US) 1998-01-21 EP disclosed
US-5665562-A SCINTILLATION PROXIMITY ASSAY USING RADIOISOTOPE-LABELLED REAGENT AMERSHAM INTERNATIONAL PLC (GB) 1997-09-09 US disclosed
WO-1997029114-A1 BIOTIN-CONTAINING COMPOUNDS, BIOTINYLATION REAGENTS AND METHODS BOARD OF REGENTS OF THE UNIVERSITY OF WASHINGTON (US) 1997-08-14 WO disclosed
US-5646126-A ANTITUMOR AGENTS EFFECTIVE AGAINST MULTIPLE DRUG RESISTANT CELL LINES EPOCH PHARMACEUTICALS 1997-07-08 US disclosed
WO-1997012896-A1 SELECTIVE BINDING COMPLEMENTARY OLIGONUCLEOTIDES EPOCH PHARMACEUTICALS, INC. (US) 1997-04-10 WO disclosed
EP-0748331-A1 MODIFIED OLIGONUCLEOTIDE DUPLEXES HAVING ANTICANCER ACTIVITY EPOCH PHARMACEUTICALS, INC. (US) 1996-12-18 EP disclosed
WO-1996032496-A2 COVALENTLY LINKED OLIGONUCLEOTIDE MINOR GROOVE BINDER CONJUGATES MICROPROBE CORPORATION (US) 1996-10-17 WO disclosed
WO-1995023162-A1 MODIFIED OLIGONUCLEOTIDE DUPLEXES HAVING ANTICANCER ACTIVITY MICROPROBE CORPORATION (US) 1995-08-31 WO disclosed
US-5419966-A Solid support for synthesis of 3'-tailed oligonucleotides MICROPROBE CORPORATION (US) 1995-05-30 US disclosed
EP-0547142-A4 MICROPROBE CORP (US) 1995-01-18 EP disclosed
WO-1994017092-A1 BIFUNCTIONAL CROSSLINKING OLIGONUCLEOTIDES ADAPTED FOR LINKING TO A DESIRED GENE SEQUENCE OF INVADING ORGANISM OR CELL MICROPROBE CORPORATION (US) 1994-08-04 WO disclosed
EP-0547142-A1 SOLID SUPPORT SYNTHESIS OF 3'-TAILED OLIGONUCLEOTIDES VIA A LINKING MOLECULE EPOCH PHARMACEUTICALS, INC. (US) 1993-06-23 EP disclosed
WO-1992003464-A1 SOLID SUPPORT SYNTHESIS OF 3'-TAILED OLIGONUCLEOTIDES VIA A LINKING MOLECULE MICROPROBE CORPORATION (US) 1992-03-05 WO disclosed
WO-1992003464-A1 SOLID SUPPORT SYNTHESIS OF 3'-TAILED OLIGONUCLEOTIDES VIA A LINKING MOLECULE MICROPROBE CORPORATION (US) 1992-03-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (50 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140155585-A1 HAPTENS OF RISPERIDONE AND PALIPERIDONE PRLHR, HRH1, OPRL1 CA1 4448/4885CA2 4630/4885CA4 4081/4885
US-20020052482-A1 Covalently linked oligonucleotide minor grove binder conjugates CD2BP2, MICA, SELPLG CA1 4363/4885CA2 4524/4885CA4 3522/4885
US-10793644-B2 Antibodies to risperidone haptens and use thereof HTR4, HTR3C, OPRL1 CA1 3959/4885CA2 4273/4885CA4 3544/4885
US-20240010657-A1 BIOTIN DERIVATIVES BTD, HLCS, BRI3BP CA1 4859/4885CA2 4696/4885CA4 4354/4885
US-20140163206-A1 HAPTENS OF ARIPIPRAZOLE HRH2, HRH4, CYP2D6 CA1 1726/4885CA2 1955/4885CA4 1237/4885
US-20180105606-A1 ANTIBODIES TO QUETIAPINE HAPTENS AND USE THEREOF HTR4, HTR3C, SLC6A4 CA1 3821/4885CA2 3800/4885CA4 2714/4885
US-20020076739-A1 Rapid quantitative analysis of proteins or protein function in complex mixtures PRTN3, RPS27A, PA2G4 CA1 2941/4885CA2 3539/4885CA4 3418/4885
US-20140017797-A1 PROTEIN AFFINITY TAG AND USES THEREOF PTMS, ALPG, TPX2 CA1 1648/4885CA2 1002/4885CA4 1108/4885
US-20050064463-A1 Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders DDB1, LIG3, MSH2 CA1 2672/4885CA2 3638/4885CA4 3648/4885
US-11225527-B2 Antibodies to paliperidone haptens and use thereof LY96, OPRL1, HTR3C CA1 4339/4885CA2 4111/4885CA4 3081/4885
US-20170044372-A1 CELL TRACKING REAGENTS AND THEIR METHODS OF USE MKI67, DCX, NES CA1 3205/4885CA2 3734/4885CA4 3300/4885
US-10166296-B2 Haptens of aripiprazole HRH2, HRH4, CYP2D6 CA1 1726/4885CA2 1955/4885CA4 1237/4885
US-11731982-B2 Biotin derivatives BTD, HLCS, BRI3BP CA1 4859/4885CA2 4696/4885CA4 4354/4885
US-10370457-B2 Antibodies to paliperidone haptens and use thereof LY96, OPRL1, HTR3C CA1 4339/4885CA2 4111/4885CA4 3081/4885
US-11226345-B2 Antibodies to olanzapine haptens and use thereof HTR4, HTR3C, HTR1A CA1 3724/4885CA2 4350/4885CA4 3519/4885
US-20140057305-A1 Antibodies to Quetiapine Haptens and Use Thereof HTR4, HTR3C, SLC6A4 CA1 3821/4885CA2 3800/4885CA4 2714/4885
US-20180117169-A1 HAPTENS OF ARIPIPRAZOLE HRH2, HRH4, CYP2D6 CA1 1726/4885CA2 1955/4885CA4 1237/4885
US-20170298147-A1 ANTIBODIES TO PALIPERIDONE HAPTENS AND USE THEREOF LY96, OPRL1, HTR3C CA1 4339/4885CA2 4111/4885CA4 3081/4885
US-20140011255-A1 Biotin Derivatives BTD, HLCS, BRI3BP CA1 4859/4885CA2 4696/4885CA4 4354/4885
US-10465013-B2 Antibodies to quetiapine haptens and use thereof HTR4, HTR3C, SLC6A4 CA1 3821/4885CA2 3800/4885CA4 2714/4885
US-20140057301-A1 Antibodies to Risperidone Haptens and Use Thereof HTR4, HTR3C, OPRL1 CA1 3959/4885CA2 4273/4885CA4 3544/4885
US-10712353-B2 Antibodies to olanzapine haptens and use thereof HTR4, HTR3C, HTR1A CA1 3724/4885CA2 4350/4885CA4 3519/4885
US-20190322681-A1 Biotin Derivatives BTD, HLCS, BRI3BP CA1 4859/4885CA2 4696/4885CA4 4354/4885
US-20200399400-A1 ANTIBODIES TO RISPERIDONE HAPTENS AND USE THEREOF HTR4, HTR3C, OPRL1 CA1 3959/4885CA2 4273/4885CA4 3544/4885
US-20070166723-A1 Hybridization-triggered fluorescent detection of nucleic acids DDX21, RNGTT, NOP2 CA1 739/4885CA2 692/4885CA4 494/4885
US-20140213766-A1 HAPTENS OF OLANZIPINE OPRL1, ADRA1D, CHRNA2 CA1 2147/4885CA2 1803/4885CA4 2885/4885
US-10570250-B2 Dibenzosilole monomers and polymers and methods for their preparation and use DDOST, DDT, DAD1 CA1 1725/4885CA2 4283/4885CA4 3328/4885
US-20030113765-A1 Hybridization-triggered fluorescent detection of nucleic acids DDX21, RNGTT, NOP2 CA1 739/4885CA2 692/4885CA4 494/4885
US-20180355098-A1 DIBENZOSILOLE MONOMERS AND POLYMERS AND METHODS FOR THEIR PREPARATION AND USE DDOST, DDT, DAD1 CA1 1725/4885CA2 4283/4885CA4 3328/4885
US-20200040107-A1 ANTIBODIES TO QUETIAPINE HAPTENS AND USE THEREOF HTR4, HTR3C, SLC6A4 CA1 3821/4885CA2 3800/4885CA4 2714/4885
US-20090048427-A1 HYBRIDIZATION AND MISMATCH DISCRIMINATION USING OLIGONUCLEOTIDES CONJUGATED TO MINOR GROOVE BINDERS DDB1, LIG3, MSH2 CA1 2672/4885CA2 3638/4885CA4 3648/4885
US-20190338047-A1 Antibodies to Paliperidone Haptens and Use Thereof LY96, OPRL1, HTR3C CA1 4339/4885CA2 4111/4885CA4 3081/4885
US-20170247504-A1 DIBENZOSILOLE MONOMERS AND POLYMERS AND METHODS FOR THEIR PREPARATION AND USE DDOST, DDT, DAD1 CA1 1725/4885CA2 4283/4885CA4 3328/4885
US-20140213767-A1 HAPTENS OF PALIPERIDONE CD274, PIN1, LY96 CA1 4497/4885CA2 4446/4885CA4 2983/4885
US-20170204198-A1 Antibodies to Aripiprazole Haptens and Use Thereof FCER2, HTR4, HTR3C CA1 3272/4885CA2 3267/4885CA4 2388/4885
US-20180022827-A1 ANTIBODIES TO RISPERIDONE HAPTENS AND USE THEREOF HTR4, HTR3C, OPRL1 CA1 3959/4885CA2 4273/4885CA4 3544/4885
US-20030087329-A1 Differential labeling for quantitative analysis of complex protein mixtures RPS27A, PSMG3, MRTO4 CA1 1492/4885CA2 2431/4885CA4 2019/4885
US-10379105-B2 Antibodies to aripiprazole haptens and use thereof FCER2, HTR4, HTR3C CA1 3272/4885CA2 3267/4885CA4 2388/4885
US-20140057303-A1 Antibodies to Olanzapine Haptens and Use Thereof HTR4, HTR3C, HTR1A CA1 3724/4885CA2 4350/4885CA4 3519/4885
US-20120045848-A1 PYRENYLOXYSULFONIC ACID FLUORESCENT AGENTS NOP56, ANXA5, ANXA6 CA1 818/4885CA2 1054/4885CA4 619/4885
US-20070031973-A1 Triazine derivatives as universal peptide isotope tag reagents (U-PIT) QPCTL, PTMS, RPS27A CA1 1564/4885CA2 3272/4885CA4 2174/4885
US-20040052784-A1 Biotin derivatives BTD, HLCS, PROC CA1 2875/4885CA2 4580/4885CA4 4051/4885
US-20190331663-A1 Antibodies to Aripiprazole Haptens and Use Thereof FCER2, HTR4, HTR3C CA1 3272/4885CA2 3267/4885CA4 2388/4885
US-20060228325-A1 Water soluble multi-biotin-containing compounds BTD, HLCS, VNN1 CA1 3043/4885CA2 3940/4885CA4 4092/4885
US-20170240653-A1 ANTIBODIES TO OLANZAPINE HAPTENS AND USE THEREOF HTR4, HTR3C, HTR1A CA1 3724/4885CA2 4350/4885CA4 3519/4885
US-20050136008-A1 Polybiotin compounds for magnetic resonance imaging and drug delivery BTD, BCAT1, BRD4 CA1 3221/4885CA2 2358/4885CA4 1241/4885
US-20040259164-A1 Capture and release based isotope tagged peptides and methods for using the same PTMS, RPS27A, RBBP5 CA1 3854/4885CA2 4459/4885CA4 4185/4885
US-20180149637-A1 ANTIBODIES TO ARIPIPRAZOLE HAPTENS AND USE THEREOF FCER2, HTR4, HTR3C CA1 3272/4885CA2 3267/4885CA4 2388/4885
US-20090010845-A1 Polybiotin Compounds of Magnetic Resonance Imaging and Drug Delivery BTD, BCAT1, BRD4 CA1 3194/4885CA2 2342/4885CA4 1285/4885
US-20140057299-A1 Antibodies to Aripiprazole Haptens and Use Thereof FCER2, HTR4, HTR3C CA1 3272/4885CA2 3267/4885CA4 2388/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.