Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG known ✓ | P37231 | 9/20 | 0.38 |
| ▸ | HDAC11 known ✓ | Q96DB2 | 5/20 | 0.38 |
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.38 |
| ▸ | PDE4A known ✓ | P27815 | 1/20 | 0.38 |
| ▸ | PDE3A known ✓ | Q14432 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 8/20 | 0.38 |
| ▸ | PPARA | Q07869 | 8/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | FABP4 | P15090 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL993590 | 0.99 | PPARG (0.39) | PPARGPPARDPPARAGPR84HDAC11 | |
| SCHEMBL9737418 | 0.99 | PPARG (0.39) | PPARGPPARDPPARAGPR84HDAC11 | |
| SCHEMBL39175 | 0.99 | PPARG (0.39) | PPARGPPARDPPARAGPR84HDAC11 | |
| SCHEMBL992967 | 0.99 | PPARG (0.39) | PPARGPPARDPPARAGPR84HDAC11 | |
| SCHEMBL995804 | 0.99 | PPARG (0.39) | PPARGPPARDPPARAGPR84HDAC11 | |
| SCHEMBL995960 | 0.99 | PPARG (0.39) | PPARGPPARDPPARAGPR84HDAC11 | |
| SCHEMBL995729 | 0.99 | PPARG (0.39) | PPARGPPARDPPARAGPR84HDAC11 | |
| SCHEMBL994337 | 0.99 | PPARG (0.39) | PPARGPPARDPPARAGPR84HDAC11 | |
| Ammonia Solution, Strong SCHEMBL7896973 | 0.98 | PPARG (0.38) | PPARGPPARDPPARAGPR84HDAC11 | |
| SCHEMBL3951980 | 0.95 | PPARG (0.36) | PPARGPPARDPPARAGPR84HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487409-B1 | HIGHLY AQUEOUS LIQUID CARRIER FORMULATIONS | BATTELLE MEMORIAL INSTITUTE (US) | 2009-04-22 | — | — | EP | claimed |
| US-20080250572-A1 | Stabilized body care products, household products, textiles and fabrics | LUPIA JOSEPH A | 2008-10-16 | — | — | US | claimed |
| US-20080253981-A1 | Stabilized body care products, household products, textiles and fabrics | LUPIA JOSEPH A | 2008-10-16 | — | — | US | claimed |
| US-20080221332-A1 | Hindered Amine salt compounds | WOOD MARVIN G | 2008-09-11 | — | — | US | claimed |
| US-7632795-B2 | Stabilized body care products, household products, textiles and fabrics | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2009-12-15 | — | — | US | disclosed |
| US-7615503-B2 | Stabilized body care products, household products, textiles and fabrics | CIBA SPECIALTY CHEMICALS CORP. (US) | 2009-11-10 | — | — | US | disclosed |
| US-7612026-B2 | Sterically hindered amine salts having an N-(alkoxy, cycloalkoxy or aralkoxy)2,2,6,6-tetraalkylsubstituted piperidine moiety; discoloration inhibition, colorfastness | CIBA SPECIALTY CHEMICALS CORP. (US) | 2009-11-03 | — | — | US | disclosed |
| US-7589035-B2 | Stabilized body care products, household products, textiles and fabrics | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2009-09-15 | — | — | US | disclosed |
| US-20090205144-A1 | Stabilized body care products, household products, textiles and fabrics | LUPIA JOSEPH A | 2009-08-20 | — | — | US | disclosed |
| US-20090092561-A1 | Body-care and household products and compositions comprising specific sulfur-containing compounds | BASF SE (DE) | 2009-04-09 | — | — | US | disclosed |
| US-20080250572-A1 | Stabilized body care products, household products, textiles and fabrics | LUPIA JOSEPH A | 2008-10-16 | — | — | US | disclosed |
| US-20080253981-A1 | Stabilized body care products, household products, textiles and fabrics | LUPIA JOSEPH A | 2008-10-16 | — | — | US | disclosed |
| US-20080255251-A1 | Stabilized body care products, household products, textiles and fabrics | LUPIA JOSEPH A | 2008-10-16 | — | — | US | disclosed |
| US-20080221332-A1 | Hindered Amine salt compounds | WOOD MARVIN G | 2008-09-11 | — | — | US | disclosed |
| US-7384464-B2 | Ink jet and recording material | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080253981-A1 | Stabilized body care products, household products, textiles and fabrics | DSC1, CUTA, DSG1 | PPARG 2696/4885HDAC11 128/4885ESR1 4763/4885 |
| US-20090092561-A1 | Body-care and household products and compositions comprising specific sulfur-containing compounds | DSC1, SCLY, DSG1 | PPARG 1923/4885HDAC11 695/4885ESR1 4596/4885 |
| US-20080255251-A1 | Stabilized body care products, household products, textiles and fabrics | DSC1, CUTA, DSG1 | PPARG 2696/4885HDAC11 128/4885ESR1 4763/4885 |
| US-20080221332-A1 | Hindered Amine salt compounds | SLC7A1, H1-0, SLC3A2 | PPARG 2732/4885HDAC11 657/4885ESR1 1769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.