Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Vanillin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 known ✓ | P28845 | 2/20 | 0.62 |
| ▸ | TTR known ✓ | P02766 | 1/20 | 0.61 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.60 |
| ▸ | HDAC3 known ✓ | O15379 | 1/20 | 0.58 |
| ▸ | EGFR known ✓ | P00533 | 1/20 | 0.58 |
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.58 |
| ▸ | TOP2A known ✓ | P11388 | 1/20 | 0.58 |
| ▸ | MAOA known ✓ | P21397 | 1/20 | 0.58 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.58 |
| ▸ | MAOB known ✓ | P27338 | 1/20 | 0.58 |
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.58 |
| ▸ | MMP13 known ✓ | P45452 | 1/20 | 0.58 |
| ▸ | HDAC4 known ✓ | P56524 | 1/20 | 0.58 |
| ▸ | PRKCE known ✓ | Q02156 | 1/20 | 0.58 |
| ▸ | PRKCQ known ✓ | Q04759 | 1/20 | 0.58 |
| ▸ | PRKCD known ✓ | Q05655 | 1/20 | 0.58 |
| ▸ | HDAC1 known ✓ | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC7 known ✓ | Q8WUI4 | 1/20 | 0.58 |
| ▸ | HDAC2 known ✓ | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC10 known ✓ | Q969S8 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Vanillin SCHEMBL2845894 | 0.98 | ALDH1A1 (0.93) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 | |
| Vanillin SCHEMBL1213 | 0.98 | ALDH1A1 (1.00) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 | |
| Vanillin SCHEMBL720723 | 0.98 | ALDH1A1 (1.00) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 | |
| Vanillin SCHEMBL29354839 | 0.98 | ALDH1A1 (1.00) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 | |
| Vanillin SCHEMBL28387598 | 0.96 | ALDH1A1 (0.89) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 | |
| Vanillin SCHEMBL19411839 | 0.96 | ALDH1A1 (0.96) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 | |
| Vanillin SCHEMBL8853913 | 0.96 | ALDH1A1 (0.96) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 | |
| Vanillin SCHEMBL19149274 | 0.96 | ALDH1A1 (0.96) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 | |
| Vanillin SCHEMBL20549709 | 0.96 | ALDH1A1 (0.96) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 | |
| Vanillin SCHEMBL2907529 | 0.96 | ALDH1A1 (0.96) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116008227-A | Method for rapidly detecting procyanidine content of whole peanut seed coats | 山东鲁花花生产业技术研究院有限公司 | 2023-04-25 | — | — | CN | claimed |
| CN-110879269-B | Combined identification method of cranberry extract | 浙江尖峰健康科技有限公司 | 2022-04-08 | — | — | CN | claimed |
| CN-114184773-A | Method for screening macroporous resin for purifying ephedrine | 内蒙古自治区农牧业科学院 | 2022-03-15 | — | — | CN | claimed |
| CN-110879269-A | Combined identification method of cranberry extract | 浙江尖峰健康科技有限公司 | 2020-03-13 | — | — | CN | claimed |
| CN-109211719-A | A kind of green tea and its for tea component analysis method | 信阳师范学院 | 2019-01-15 | — | — | CN | claimed |
| CN-102764356-A | Method for discriminating Wenweishu capsules | JIANGUANG GU | 2012-11-07 | — | — | CN | claimed |
| CN-101183098-A | Detection method of chloromycetin eyedrops | NAN FANG (CN) | 2008-05-21 | — | — | CN | claimed |
| CN-101073605-A | Bistort Rhizome effective component and its use | SHENYANG MEDICINAL SCIENCE UNI (CN) | 2007-11-21 | — | — | CN | claimed |
| CN-1726962-A | Method for controlling quality of cudrania wood and preparation | PU GUIBAO (CN) | 2006-02-01 | — | — | CN | claimed |
| JP-8259557-A | — | — | None | — | — | JP | disclosed |
| US-20260108574-A1 | HERBAL COMPOSITION FOR TREATING METABOLIC DISORDERS IN MAMMALS | M/S NATURAL AND ESSENTIAL OILS PRIVATE LIMITED (IN) | 2026-04-23 | — | — | US | disclosed |
| US-20250354109-A1 | A PREPARATION METHOD OF SILAGE | GUIZHOU UNIVERSITY (CN) | 2025-11-20 | — | — | US | disclosed |
| US-20250270485-A1 | BREWING WITH THERMOSTABLE AMG VARIANTS | NOVOZYMES A/S (DK) | 2025-08-28 | — | — | US | disclosed |
| US-12398365-B2 | Lactiplantibacillus plantarum for degrading tannins and saponins, and use thereof | UNIV GUIZHOU (CN) | 2025-08-26 | — | — | US | disclosed |
| EP-0815857-B1 | ANTIOBESTIC AGENT CONTAINING PROCYANIDIN AS THE ACTIVE INGREDIENT | SUNTORY LTD (JP) | 2004-09-29 | — | — | EP | disclosed |
| EP-1222865-A1 | ELEMENT FOR CIGARETTE SMOKE AND PROCESS FOR PRODUCING THE SAME | Daicel Chemical Industries, Ltd. (JP) | 2002-07-17 | — | — | EP | disclosed |
| US-6420181-B1 | DETECTING PREFERENTIAL PARTICLE IN SOLUTION; OBTAIN SOLUTION CONTAINING PARTICLE, MIX WITH SOLVENT, INSERT INTO TUBE, INCUBATE WITH CHROMOGENIC DETECTION INDICATOR, MONITOR SAMPLE FOR SIGNAL | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2002-07-16 | — | — | US | disclosed |
| US-6294190-B1 | TAMARIND SEED COAT EXTRACT, | SUNTORY LIMITED (JP) | 2001-09-25 | — | — | US | disclosed |
| EP-0815857-A1 | ANTIOBESTIC AGENT CONTAINING PROCYANIDIN AS THE ACTIVE INGREDIENT | SUNTORY LIMITED (JP) | 1998-01-07 | — | — | EP | disclosed |
| JP-H08259557-A | NEW TANNINS AND INHIBITOR TO LIPASE CONTAINING THE SAME AS ACTIVE INGREDIENT | LOTTE CO LTD | 1996-10-08 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260108574-A1 | HERBAL COMPOSITION FOR TREATING METABOLIC DISORDERS IN MAMMALS | LIPC, ADIPOR2, ADIPOR1 | HSD11B1 748/4885TTR 1898/4885CA2 1979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.