Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.45 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL125129 | 0.98 | CYP3A4 (0.52) | CYP3A4MAPTKDM4EATMIDO1 | |
| Bromide SCHEMBL11038149 | 0.95 | CYP3A4 (0.50) | CYP3A4MAPTKDM4EATMIDO1 | |
| Water SCHEMBL13583453 | 0.95 | CYP3A4 (0.56) | CYP3A4MAPTKDM4EATMIDO1 | |
| Iodide SCHEMBL4994541 | 0.95 | CYP3A4 (0.50) | CYP3A4MAPTKDM4EATMIDO1 | |
| SCHEMBL5839383 | 0.85 | LTA4H (0.46) | CYP3A4MAPTKDM4EHTTRAB9A | |
| SCHEMBL13958950 | 0.85 | RAB9A (0.59) | MAPTIDO1CYP2D6MEN1KMT2A | |
| Methacrylic Acid SCHEMBL31424214 | 0.84 | RIPK1 (0.45) | CYP3A4MAPTKDM4EATMCYP2D6 | |
| SCHEMBL13958852 | 0.81 | BCHE (0.69) | MAPTATMMEN1KMT2ACYP2C19 | |
| SCHEMBL14145021 | 0.81 | CYP3A4 (0.50) | CYP3A4MAPTKDM4EATMIDO1 | |
| SCHEMBL14433569 | 0.81 | PRMT6 (0.42) | CYP3A4MAPTKDM4EKMT2ALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8772186-B2 | Reversible color-changing sanitizer-indicating nonwoven wipe | ILLINOIS TOOL WORKS INC. (US) | 2014-07-08 | — | — | US | claimed |
| US-8772184-B2 | Reversible color-changing sanitizer-indicating nonwoven wipe | ILLINOIS TOOL WORKS INC. (US) | 2014-07-08 | — | — | US | claimed |
| US-20130104325-A1 | REVERSIBLE COLOR-CHANGING SANITIZER-INDICATING NONWOVEN WIPE | ILLINOIS TOOL WORKS INC. (US) | 2013-05-02 | — | — | US | claimed |
| EP-2414579-A2 | REVERSIBLE COLOR-CHANGING SANITIZER-INDICATING NONWOVEN WIPE | Illinois Tool Works Inc. (US) | 2012-02-08 | — | — | EP | claimed |
| WO-2010117520-A2 | REVERSIBLE COLOR-CHANGING SANITIZER-INDICATING NONWOVEN WIPE | ILLINOIS TOOL WORKS INC. (US) | 2010-10-14 | — | — | WO | claimed |
| US-20100247371-A1 | REVERSIBLE COLOR-CHANGING SANITIZER-INDICATING NONWOVEN WIPE | ILLINOIS TOOL WORKS INC. (US) | 2010-09-30 | — | — | US | claimed |
| CN-101704755-A | Method for preparing p-tert-butylbenzylamine | UNIV HUAZHONG AGRICULTURAL | 2010-05-12 | — | — | CN | claimed |
| CN-114403143-B | Anti-freezing quaternary ammonium salt composition and preparation method and application thereof | 广州蓝月亮实业有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-115039774-B | Compound disinfectant for controlling banana equine diseases and panama diseases and application thereof | 苏州艾科尔化工科技有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-114403144-B | Microbial-killing quaternary ammonium salt composition and preparation method and application thereof | 广州蓝月亮实业有限公司 | 2024-01-19 | — | — | CN | disclosed |
| CN-117242165-A | Enzymatic floor cleaning compositions | 埃科莱布美国股份有限公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-116438290-A | Structured premixes and liquid compositions containing them | 宝洁公司 | 2023-07-14 | — | — | CN | disclosed |
| EP-3150760-A1 | REVERSIBLE COLOR-CHANGING SANITIZER-INDICATING NONWOVEN WIPE | Illinois Tool Works, Inc. (US) | 2017-04-05 | — | — | EP | disclosed |
| EP-2952626-A1 | Reversible color-changing sanitizer-indicating nonwoven wipe | Illinois Tool Works Inc. (US) | 2015-12-09 | — | — | EP | disclosed |
| CN-101704755-A | Method for preparing p-tert-butylbenzylamine | UNIV HUAZHONG AGRICULTURAL | 2010-05-12 | — | — | CN | disclosed |
| US-20050186258-A1 | Antimicrobial medical gloves | ALLEGIANCE CORPORATION | 2005-08-25 | — | — | US | disclosed |
| EP-1032263-B1 | SURFACTANT-BASED ANTIMICROBIAL COMPOSITIONS AND METHODS FOR USING SAME | WOODWARD LAB INC (US) | 2004-06-09 | — | — | EP | disclosed |
| US-4998984-A | Premoistened prepackaged disposable disinfectant wiper | MCCLENDON EVELYN (US) | 1991-03-12 | — | — | US | disclosed |
| US-4764440-A | ELECTROLYTIC CELLS | EVEREADY BATTERY COMPANY (US) | 1988-08-16 | — | — | US | disclosed |