Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.32 |
| ▸ | HSP90AB1 known ✓ | P08238 | 1/20 | 0.32 |
| ▸ | HSP90AA1 known ✓ | P07900 | 1/20 | 0.31 |
| ▸ | HTR2B known ✓ | P41595 | 1/20 | 0.31 |
| ▸ | PDE4D known ✓ | Q08499 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3341380 | 1.00 | CASP1 (0.47) | CASP1LMNAADORA2AADORA1POLB | |
| Hydrochloric Acid SCHEMBL28299308 | 1.00 | CASP1 (0.47) | CASP1LMNAADORA2AADORA1POLB | |
| Hydrochloric Acid SCHEMBL30388037 | 1.00 | CASP1 (0.47) | CASP1LMNAADORA2AADORA1POLB | |
| Hydrochloric Acid SCHEMBL586764 | 1.00 | CASP1 (0.47) | CASP1LMNAADORA2AADORA1POLB | |
| Hydrochloric Acid SCHEMBL28275754 | 0.95 | CASP1 (0.44) | CASP1LMNAADORA2AADORA1POLB | |
| SCHEMBL8465809 | 0.94 | CASP1 (0.50) | CASP1LMNAADORA2AADORA1POLB | |
| SCHEMBL9579151 | 0.94 | CASP1 (0.50) | CASP1LMNAADORA2AADORA1POLB | |
| SCHEMBL175612 | 0.94 | CASP1 (0.50) | CASP1LMNAADORA2AADORA1POLB | |
| SCHEMBL25853 | 0.94 | — | — | |
| SCHEMBL29900242 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 357 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260108946-A1 | LOW-TEMPERATURE CASE HARDENING OF ADDITIVE MANUFACTURED ARTICLES AND MATERIALS AND TARGETED APPLICATION OF SURFACE MODIFICATION | SWAGELOK CO (US) | 2026-04-23 | — | — | US | claimed |
| US-20260002244-A1 | ACTIVATION OF SELF-PASSIVATING METALS USING REAGENT COATINGS FOR LOW TEMPERATURE NITROCARBURIZATION IN THE PRESENCE OF OXYGEN-CONTAINING GAS | SWAGELOK CO (US) | 2026-01-01 | — | — | US | claimed |
| US-12435406-B2 | Activation of self-passivating metals using reagent coatings for low temperature nitrocarburization in the presence of oxygen-containing gas | SWAGELOK COMPANY (US) | 2025-10-07 | — | — | US | claimed |
| CN-114929924-B | Chemical activation of self-passivating metals | 斯瓦戈洛克公司 | 2025-02-14 | — | — | CN | claimed |
| CN-119300479-A | Efficient battery assembly and preparation method thereof | 江苏东鋆光伏科技有限公司 | 2025-01-10 | — | — | CN | claimed |
| CN-115178294-B | PDI functionalized 3D g-C3N4Preparation method and application of photocatalyst | 江苏大学 | 2024-12-06 | — | — | CN | claimed |
| CN-115404081-B | Passivating agent for repairing heavy metal arsenic, lead and cadmium combined pollution and application thereof | 广西壮族自治区环境保护科学研究院 | 2024-10-11 | — | — | CN | claimed |
| CN-118324123-A | Nitrogen-doped carbon micro-tube and preparation method thereof | 大连理工大学 | 2024-07-12 | — | — | CN | claimed |
| CN-118147691-A | Preparation method of hydrogen production catalyst in carbon-hydrogen co-production | 黑龙江博能绿色能源科技股份有限公司 | 2024-06-07 | — | — | CN | claimed |
| CN-114471655-B | Preparation method of composite photocatalyst capable of efficiently generating hydrogen peroxide without adding sacrificial agent under visible light | 山西省生态环境保护服务中心(山西省环境规划院) | 2024-05-31 | — | — | CN | claimed |
| WO-2016057253-A1 | DISPERSANT FOR USE IN SYNTHESIS OF POLYARYLETHERKETONES | TICONA LLC (US) | 2016-04-14 | — | — | WO | claimed |
| EP-1576073-B1 | FIRE RESISTANT MATERIAL | COMMW SCIENT IND RES ORG (AU) | 2012-02-15 | — | — | EP | claimed |
| US-20110281981-A1 | FIRE RESISTANT MATERIAL | THE BOEING COMPANY | 2011-11-17 | — | — | US | claimed |
| WO-2004039916-A9 | FIRE RESISTANT MATERIAL | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2009-10-29 | — | — | WO | claimed |
| US-20070194289-A1 | Fire resistant material | Commonwealth Scientific & Industrial Research Org. a Australian Corporation | 2007-08-23 | — | — | US | claimed |
| US-20050019579-A1 | Carbon material and process of manufacturing | CHAPMAN LLOYD R (US) | 2005-01-27 | — | — | US | claimed |
| CN-1177973-C | Nano material modified high strength paper and its preparation method | 中国科学院化学研究所 | 2004-12-01 | — | — | CN | claimed |
| US-20040142173-A1 | Carbon material and process of manufacturing | EQUITY ENTERPRISES | 2004-07-22 | — | — | US | claimed |
| CN-1414176-A | Nano material modified high strength paper and its preparation method | CHEMICAL INST CHINESE ACADEMY (CN) | 2003-04-30 | — | — | CN | claimed |
| US-4028333-A | POLYOLEFINS | VELSICOL CHEMICAL CORPORATION (US) | 1977-06-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260002244-A1 | ACTIVATION OF SELF-PASSIVATING METALS USING REAGENT COATINGS FOR LOW TEMPERATURE NITROCARBURIZATION IN THE PRESENCE OF OXYGEN-CONTAINING GAS | NOS2, GSDMD, NOS1 | GAA 2271/4885HSP90AB1 698/4885HSP90AA1 954/4885 |
| US-20260108946-A1 | LOW-TEMPERATURE CASE HARDENING OF ADDITIVE MANUFACTURED ARTICLES AND MATERIALS AND TARGETED APPLICATION OF SURFACE MODIFICATION | NOS2, NIT2, NSUN2 | GAA 667/4885HSP90AB1 151/4885HSP90AA1 186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.