Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 4/20 | 0.87 |
| ▸ | CASP2 | P42575 | 1/20 | 0.62 |
| ▸ | FAAH | O00519 | 5/20 | 0.60 |
| ▸ | NAAA | Q02083 | 1/20 | 0.59 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.55 |
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9549112 | 0.98 | DNM1 (0.90) | DNM1CASP2FAAHNAAASLC6A5 | |
| SCHEMBL1601857 | 0.98 | DNM1 (0.90) | DNM1CASP2FAAHNAAASLC6A5 | |
| SCHEMBL27964228 | 0.98 | DNM1 (0.90) | DNM1CASP2FAAHNAAASLC6A5 | |
| SCHEMBL1603004 | 0.98 | DNM1 (0.90) | DNM1CASP2FAAHNAAASLC6A5 | |
| SCHEMBL9665089 | 0.98 | DNM1 (0.90) | DNM1CASP2FAAHNAAASLC6A5 | |
| SCHEMBL18632644 | 0.98 | DNM1 (0.90) | DNM1CASP2FAAHNAAASLC6A5 | |
| SCHEMBL19479185 | 0.98 | DNM1 (0.90) | DNM1CASP2FAAHNAAASLC6A5 | |
| SCHEMBL22907872 | 0.95 | DNM1 (0.84) | DNM1CASP2FAAHNAAASLC6A5 | |
| SCHEMBL22907945 | 0.95 | DNM1 (0.84) | DNM1CASP2FAAHNAAASLC6A5 | |
| SCHEMBL21419343 | 0.95 | DNM1 (0.84) | DNM1CASP2FAAHNAAASLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10781405-B2 | Polyetheramine compositions for laundry detergents | STEPAN COMPANY (US) | 2020-09-22 | — | — | US | disclosed |
| EP-3458567-A1 | POLYETHERAMINE COMPOSITIONS FOR LAUNDRY DETERGENTS | Stepan Company (US) | 2019-03-27 | — | — | EP | disclosed |
| US-20190085266-A1 | POLYETHERAMINE COMPOSITIONS FOR LAUNDRY DETERGENTS | STEPAN COMPANY | 2019-03-21 | — | — | US | disclosed |
| EP-2475756-B1 | LIQUID CLEANING COMPOSITIONS CONTAINING SULFONATED ESTOLIDES AND ALKYL ESTER SULFONATES | STEPAN CO (US) | 2019-01-16 | — | — | EP | disclosed |
| WO-2017200737-A1 | POLYETHERAMINE COMPOSITIONS FOR LAUNDRY DETERGENTS | STEPAN COMPANY (US) | 2017-11-23 | — | — | WO | disclosed |
| EP-2382295-B1 | CLEANER COMPOSITIONS OF SULFONATED ESTOLIDES AND USES THEREOF | STEPAN CO (US) | 2016-05-18 | — | — | EP | disclosed |
| EP-2277860-B1 | Compositions comprising sulfonated estolides and alkyl ester sulfonates, methods of making them, and compositions and processes employing them | STEPAN CO (US) | 2015-08-19 | — | — | EP | disclosed |
| EP-2831139-A1 | SURFACTANTS AND SOLVENTS CONTAINING DIELS-ALDER ADDUCTS | Stepan Company (US) | 2015-02-04 | — | — | EP | disclosed |
| EP-2247574-B1 | SULFONATED ESTOLIDES AND OTHER DERIVATIVES OF FATTY ACIDS, METHODS OF MAKING THEM, AND COMPOSITIONS AND PROCESSES EMPLOYING THEM | STEPAN CO (US) | 2015-01-07 | — | — | EP | disclosed |
| EP-2270122-B1 | Sulfonated estolides and other derivatives of fatty acids, methods of making them, and compositions and processes employing them | STEPAN CO (US) | 2015-01-07 | — | — | EP | disclosed |
| EP-2270122-A2 | Sulfonated estolides and other derivatives of fatty acids, methods of making them, and compositions and processes employing them | STEPAN COMPANY (US) | 2011-01-05 | — | — | EP | disclosed |
| EP-2258679-A2 | Sulfonated estolides and other derivatives of fatty acids, methods of making them, and compositions and processes employing them | STEPAN COMPANY (US) | 2010-12-08 | — | — | EP | disclosed |
| EP-2258817-A2 | Sulfonated estolides and other derivatives of fatty acids, methods of making them, and compositions and processes employing them | STEPAN COMPANY (US) | 2010-12-08 | — | — | EP | disclosed |
| EP-2247574-A2 | SULFONATED ESTOLIDES AND OTHER DERIVATIVES OF FATTY ACIDS, METHODS OF MAKING THEM, AND COMPOSITIONS AND PROCESSES EMPLOYING THEM | STEPAN COMPANY (US) | 2010-11-10 | — | — | EP | disclosed |
| WO-2010085247-A1 | SULFONATED ESTOLIDES AND OTHER DERIVATIVES OF FATTY ACIDS AND USES THEREOF | STEPAN COMPANY (US) | 2010-07-29 | — | — | WO | disclosed |
| US-20100184855-A1 | Hard Surface Cleaner Compositions of Sulfonated Estolides and Other Derivatives of Fatty Acids and Uses Thereof | STEPAN COMPANY | 2010-07-22 | — | — | US | disclosed |
| US-7666828-B2 | Sulfonated estolides and other derivatives of fatty acids, methods of making them, and compositions and processes employing them | STEPAN COMPANY (US) | 2010-02-23 | — | — | US | disclosed |
| US-20100016198-A1 | Compositions Comprising Sulfonated Estolides And Alkyl Ester Sulfonates, Methods Of Making Them, And Compositions And Processes Employing Them | STEPAN COMPANY | 2010-01-21 | — | — | US | disclosed |
| WO-2009094336-A2 | SULFONATED ESTOLIDES AND OTHER DERIVATIVES OF FATTY ACIDS, METHODS OF MAKING THEM, AND COMPOSITIONS AND PROCESSES EMPLOYING THEM | STEPAN COMPANY (US) | 2009-07-30 | — | — | WO | disclosed |
| US-20090188055-A1 | SULFONATED ESTOLIDES AND OTHER DERIVATIVES OF FATTY ACIDS, METHODS OF MAKING THEM, AND COMPOSITIONS AND PROCESSES EMPLOYING THEM | STEPAN COMPANY (US) | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184855-A1 | Hard Surface Cleaner Compositions of Sulfonated Estolides and Other Derivatives of Fatty Acids and Uses Thereof | STS, ELOVL6, ELOVL1 | DNM1 1212/4885CASP2 3069/4885FAAH 159/4885 |
| US-20090188055-A1 | SULFONATED ESTOLIDES AND OTHER DERIVATIVES OF FATTY ACIDS, METHODS OF MAKING THEM, AND COMPOSITIONS AND PROCESSES EMPLOYING THEM | STS, ABHD16A, HDHD5 | DNM1 3242/4885CASP2 2552/4885FAAH 12/4885 |
| US-20100016198-A1 | Compositions Comprising Sulfonated Estolides And Alkyl Ester Sulfonates, Methods Of Making Them, And Compositions And Processes Employing Them | STS, ABHD16A, DEGS1 | DNM1 3750/4885CASP2 2630/4885FAAH 245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.