Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.55 |
| ▸ | SRC known ✓ | P12931 | 1/20 | 0.54 |
| ▸ | GAA known ✓ | P10253 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.54 |
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | INSR | P06213 | 1/20 | 0.54 |
| ▸ | IGF1R | P08069 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 10/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | CASP1 | P29466 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | HBB | P68871 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29358228 | 1.00 | ADRA2A (0.55) | ADRA2AALDH1A1SMN1; SMN2HTTINSR | |
| SCHEMBL34000 | 0.98 | ALDH1A1 (0.55) | ADRA2AALDH1A1SMN1; SMN2HTTINSR | |
| SCHEMBL29355053 | 0.98 | ALDH1A1 (0.55) | ADRA2AALDH1A1SMN1; SMN2HTTINSR | |
| SCHEMBL6279763 | 0.89 | ADRA2A (0.49) | ADRA2AALDH1A1SMN1; SMN2HTTINSR | |
| SCHEMBL11971676 | 0.88 | HSP90AB1 (0.55) | ADRA2AALDH1A1SMN1; SMN2HTTINSR | |
| SCHEMBL8442813 | 0.88 | MAPT (0.67) | ALDH1A1SMN1; SMN2HTTMAPTKMT2A | |
| SCHEMBL11972261 | 0.87 | ALDH1A1 (0.53) | ADRA2AALDH1A1SMN1; SMN2HTTINSR | |
| SCHEMBL11971719 | 0.85 | ALDH1A1 (0.51) | ADRA2AALDH1A1SMN1; SMN2HTTINSR | |
| SCHEMBL11971869 | 0.85 | ALDH1A1 (0.51) | ADRA2AALDH1A1SMN1; SMN2HTTINSR | |
| SCHEMBL6344692 | 0.84 | MAPT (0.50) | ADRA2AALDH1A1SMN1; SMN2HTTINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 261 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112955112-A | Two-component system for artificial hair coloring | 汉高股份有限及两合公司 | 2021-06-11 | — | — | CN | claimed |
| US-12622853-B2 | Composition comprising a particular oxidation dye precursor and a particular amino silicone | L'OREAL (FR) | 2026-05-12 | — | — | US | disclosed |
| EP-4734950-A1 | COMPOSITION COMPRISING HYALURONIC ACID AND/OR A DERIVATIVE THEREOF, AN ANIONIC SURFACTANT, AN ALKALINE AGENT, A DYE, A SOLID FATTY ALCOHOL AND A LIQUID FATTY ALCOHOL | L'OREAL (FR) | 2026-05-06 | — | — | EP | disclosed |
| EP-4734917-A1 | COMPOSITION COMPRISING A PARTICULAR BASE AMMONIUM BICARBONATE AND FATTY ACID | L'OREAL (FR) | 2026-05-06 | — | — | EP | disclosed |
| EP-4262691-B1 | COSMETIC COMPOSITION COMPRISING A COMBINATION OF TWO PARTICULAR COUPLERS AND N,N-DICARBOXYMETHYLGLUTAMIC ACID AND/OR ITS SALTS | OREAL (FR) | 2026-04-08 | — | — | EP | disclosed |
| US-12583876-B2 | Branched organosilicon compound, method of preparing same, and related compositions | DOW SILICONES CORPORATION (US) | 2026-03-24 | — | — | US | disclosed |
| EP-4673228-A1 | GEL HAVING IMPROVED USAGE PROPERTIES, FOR OXIDATIVELY CHANGING THE COLOR OF KERATIN FIBERS | Henkel AG & Co. KGaA (DE) | 2026-01-07 | — | — | EP | disclosed |
| EP-3493878-B1 | COSMETIC COMPOSITION COMPRISING CURED SILICONE MATERIALS | DOW SILICONES CORP (US) | 2025-10-08 | — | — | EP | disclosed |
| US-20250302715-A1 | COMPOSITION COMPRISING N,N-DICARBOXYMETHYLGLUTAMIC ACID, AT LEAST ONE FATTY ALCOHOL, AT LEAST ONE FATTY ACID, AT LEAST ONE POLYOL, AT LEAST ONE ALKALINE AGENT AND OPTIONALLY AT LEAST ONE DYE | L'OREAL (FR) | 2025-10-02 | — | — | US | disclosed |
| US-12398270-B2 | Acrylate-functional branched organosilicon compound, method of preparing same, and copolymer formed therewith | DOW SILICONES CORPORATION (US) | 2025-08-26 | — | — | US | disclosed |
| EP-1116711-A2 | 2-aminoalkyl-1,4-diaminobenzene derivatives and dye composition containing these compounds | Wella Aktiengesellschaft (DE) | 2001-07-18 | — | — | EP | disclosed |
| EP-1110942-A2 | Process for the preparation of 2-aminomethyl-1,4-diamino-benzene and salts thereof, and their use in dyeing composition for keratin fibers | Wella Aktiengesellschaft (DE) | 2001-06-27 | — | — | EP | disclosed |
| WO-2001007009-A1 | LYSINE OXIDASE LINKAGE OF AGENTS TO TISSUE | PERICOR SCIENCE, INC. (US) | 2001-02-01 | — | — | WO | disclosed |
| WO-2001006829-A2 | LINKAGE OF AGENTS TO TISSUE | PERICOR SCIENCE, INC. (US) | 2001-02-01 | — | — | WO | disclosed |
| EP-0727203-B1 | Oxidation hair dye | WELLA AG (DE) | 2000-12-27 | — | — | EP | disclosed |
| EP-1052252-A1 | Diaminobenzene derivatives and dyeing preparations containing them | Wella Aktiengesellschaft (DE) | 2000-11-15 | — | — | EP | disclosed |
| EP-0727203-A1 | Oxidation hair dye | Wella Aktiengesellschaft (DE) | 1996-08-21 | — | — | EP | disclosed |
| WO-1990014818-A1 | OXIDATION HAIR COLORANT | WELLA AKTIENGESELLSCHAFT (DE) | 1990-12-13 | — | — | WO | disclosed |
| EP-0400330-A1 | Oxidation hair dyes | Wella Aktiengesellschaft (DE) | 1990-12-05 | — | — | EP | disclosed |
| US-4883656-A | AMINO PHENOLS AND AROMATIC DIAMINES | WELLA AKTIENGESELLSCHAFT (DE) | 1989-11-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12583876-B2 | Branched organosilicon compound, method of preparing same, and related compositions | OXSR1, BRS3, NPSR1 | ADRA2A 817/4885SRC 759/4885GAA 4501/4885 |
| US-20250302715-A1 | COMPOSITION COMPRISING N,N-DICARBOXYMETHYLGLUTAMIC ACID, AT LEAST ONE FATTY ALCOHOL, AT LEAST ONE FATTY ACID, AT LEAST ONE POLYOL, AT LEAST ONE ALKALINE AGENT AND OPTIONALLY AT LEAST ONE DYE | KRT18, DSG1, FPGS | ADRA2A 4370/4885SRC 3845/4885GAA 760/4885 |
| US-12622853-B2 | Composition comprising a particular oxidation dye precursor and a particular amino silicone | KRT18, SCNN1B, PLOD3 | ADRA2A 1479/4885SRC 1705/4885GAA 4765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.