Hydrochloric Acid

Hydrochloric Acid

SCHEMBL76739

CCC(C)[C@H](N)C(=O)OC.Cl

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DPP4 known ✓ P27487 12/20 0.43
CA2 known ✓ P00918 1/20 0.39
DPP8 Q6V1X1 8/20 0.43
DPP9 Q86TI2 7/20 0.43
IARS1 P41252 3/20 0.41
CA1 P00915 1/20 0.39
DPP7 Q9UHL4 7/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4284558 1.00 DPP4 (0.43) DPP4DPP8DPP9IARS1CA1
Hydrochloric Acid SCHEMBL4284560 1.00 DPP4 (0.43) DPP4DPP8DPP9IARS1CA1
Hydrochloric Acid SCHEMBL76740 1.00 DPP4 (0.43) DPP4DPP8DPP9IARS1CA1
Hydrochloric Acid SCHEMBL5420866 1.00 DPP4 (0.43) DPP4DPP8DPP9IARS1CA1
Hydrochloric Acid SCHEMBL1599029 1.00 DPP4 (0.43) DPP4DPP8DPP9IARS1CA1
Hydrochloric Acid SCHEMBL233325 1.00 DPP4 (0.43) DPP4DPP8DPP9IARS1CA1
Hydrochloric Acid SCHEMBL31084736 1.00 DPP4 (0.43) DPP4DPP8DPP9IARS1CA1
SCHEMBL76741 0.98 DPP4 (0.44) DPP4DPP8DPP9IARS1CA1
SCHEMBL1770623 0.98 DPP4 (0.44) DPP4DPP8DPP9IARS1CA1
SCHEMBL1770627 0.98 DPP4 (0.44) DPP4DPP8DPP9IARS1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 346 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119899137-A Method for preparing Fmoc-Ile-OH by chemical derivatization 杭州湃肽生化科技有限公司 2025-04-29 CN claimed
CN-119504883-A Synthesis method of RNA monomer intermediate 2' -fluoro-nucleoside modifier 安徽信佰生物医药科技有限公司 2025-02-25 CN claimed
CN-119241617-A 2 '-Deoxy-2' -fluoro-N4-substituted cytidine compound, preparation method and application thereof 河南省科学院高新技术研究中心 2025-01-03 CN claimed
CN-117903078-A Amide derivative containing 3, 4-dichloro isothiazole, preparation method and application thereof 南开大学 2024-04-19 CN claimed
CN-102262124-A Method for detecting content of L-isoleucine methyl ester hydrochloride 2011-11-30 CN claimed
EP-0397652-B1 WATER INSOLUBLE DERIVATIVES OF HYALURONIC ACID GENZYME CORP (US) 1996-06-05 EP claimed
EP-0397652-A4 WATER INSOLUBLE DERIVATIVES OF HYALURONIC ACID 1991-04-03 EP claimed
EP-0397652-A1 WATER INSOLUBLE DERIVATIVES OF HYALURONIC ACID. GENZYME CORP (US) 1990-11-22 EP claimed
US-4937270-A Water insoluble derivatives of hyaluronic acid GENZYME CORPORATION (US) 1990-06-26 US claimed
WO-1989002445-A1 WATER INSOLUBLE DERIVATIVES OF HYALURONIC ACID GENZYME CORPORATION (US) 1989-03-23 WO claimed
CN-119409587-B Amino acid derivative of 2,2 '-binaphthyl-6, 6' -dicarboxylic acid, and preparation method and application thereof Renmin Hospital Of Wuhan University (hubei General Hospital) (CN) 2026-05-26 CN disclosed
US-20260098018-A1 BICYCLIC 1,4-DIAZEPANONES AND THERAPEUTIC USES THEREOF CYTOKINETICS INC (US) 2026-04-09 US disclosed
US-20250367169-A1 FORMULATIONS FOR PERSONALIZED METHODS OF TREATMENT FAETH THERAPEUTICS INC (US) 2025-12-04 US disclosed
US-12441691-B2 Bicyclic 1,4-diazepanones and therapeutic uses thereof CYTOKINETICS, INC. (US) 2025-10-14 US disclosed
US-20250296916-A1 BICYCLIC PIPERAZINONES AND THERAPEUTIC USES THEREOF CYTOKINETICS, INC. 2025-09-25 US disclosed
WO-1989002445-A1 WATER INSOLUBLE DERIVATIVES OF HYALURONIC ACID GENZYME CORPORATION (US) 1989-03-23 WO disclosed
US-4657893-A ANTIINFLAMMATORY AGENTS SYNTEX (U.S.A.) INC. (US) 1987-04-14 US disclosed
US-4616002-A HYPOTENSIVE AGENTS CIBA-GEIGY CORPORATION (US) 1986-10-07 US disclosed
EP-0147211-A2 4H-3,1-benzoxazin-4-ones and related compounds, pharmaceutical compositions containing them, and processes for their preparation SYNTEX (U.S.A.) INC. (US) 1985-07-03 EP disclosed
US-4242507-A Sulfonic acid esters FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-12-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250296916-A1 BICYCLIC PIPERAZINONES AND THERAPEUTIC USES THEREOF MYLK2, TNNI3, TNNC1 DPP4 2115/4885CA2 1044/4885DPP8 2776/4885
US-12441691-B2 Bicyclic 1,4-diazepanones and therapeutic uses thereof MYLK2, MUSK, MYLK DPP4 2008/4885CA2 987/4885DPP8 3037/4885
US-20260098018-A1 BICYCLIC 1,4-DIAZEPANONES AND THERAPEUTIC USES THEREOF MYLK2, TNNT2, RYR1 DPP4 997/4885CA2 290/4885DPP8 2247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.