Hydrochloric Acid

Hydrochloric Acid

SCHEMBL873310

CCNC(CS)C(=O)O.Cl

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 known ✓ P35354 1/20 0.54
ACE known ✓ P12821 1/20 0.48
PTGS1 known ✓ P23219 1/20 0.36
CA2 known ✓ P00918 2/20 0.34
KDM4E B2RXH2 1/20 0.54
MAPT P10636 1/20 0.54
THRB P10828 1/20 0.54
ALOX15 P16050 1/20 0.54
NFKB1 P19838 1/20 0.54
THPO P40225 1/20 0.54
RECQL P46063 1/20 0.54
BLM P54132 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
FOLH1 Q04609 4/20 0.46
NAALAD2 Q9Y3Q0 3/20 0.38
SLC7A11 Q9UPY5 1/20 0.36
ALDH1A1 P00352 2/20 0.35
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL99739 1.00 KDM4E (0.54) KDM4EMAPTTHRBALOX15NFKB1
Hydrochloric Acid SCHEMBL30643507 0.98 KDM4E (0.52) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL499352 0.98
SCHEMBL340834 0.98
SCHEMBL1158100 0.98
SCHEMBL31425211 0.95 KDM4E (0.54) KDM4EMAPTTHRBALOX15NFKB1
Sulfurous Acid SCHEMBL25414827 0.90 KDM4E (0.48) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL25414823 0.85 KDM4E (0.44) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL4632067 0.84 ACE (0.61) KDM4EMAPTTHRBALOX15NFKB1
Hydrochloric Acid SCHEMBL11112801 0.83 SLC6A5 (0.45) KDM4EMAPTTHRBALOX15NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 413 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250161255-A1 NEW THERAPY AND PREVENTION FOR SUPPRESSING AGING-RELATED DISORDERS INCLUDING SARCOPENIA ASAGI LABS (JP) 2025-05-22 US claimed
CN-119097576-A Preventing oxidation of flavor raw material and food raw material 弗门尼舍有限公司 2024-12-10 CN claimed
EP-4470563-A1 NEW THERAPY AND PREVENTION FOR SUPPRESSING AGING-RELATED DISORDERS INCLUDING SARCOPENIA Hayano, Motoshi (JP) 2024-12-04 EP claimed
CN-118973613-A Novel treatment and prevention of aging-related abnormalities including sarcopenia 早野元词 2024-11-15 CN claimed
WO-2023145735-A1 NEW THERAPY AND PREVENTION FOR SUPPRESSING AGING-RELATED DISORDERS INCLUDING SARCOPENIA 早野 元詞 2023-08-03 WO claimed
CN-115996696-A Prevention, reduction or improvement of odor of elderly people 弗门尼舍有限公司 2023-04-21 CN claimed
CN-107653575-B A kind of preparation method for the micro-fluidic chip embedding hyaluronic acid functionalized nano-fiber film 东华大学 2019-07-23 CN claimed
CN-107653575-A A kind of preparation method for the micro-fluidic chip for embedding hyaluronic acid functionalized nano-fiber film 东华大学 2018-02-02 CN claimed
CN-105086001-A Hyaluronic acid-gelatin/acrylamide double-network aquagel and preparation method thereof UNIV CHANGCHUN TECHNOLOGY 2015-11-25 CN claimed
US-20140377328-A1 INTRAORAL SOLUBLE-TYPE FILM PREPARATION KYUKYU PHARMACEUTICAL CO., LTD. (JP) 2014-12-25 US claimed
WO-2008027350-A2 ACETAMINOPHEN PHARMACEUTICAL COMPOSITIONS AAIPHARMA INC. (US) 2008-03-06 WO claimed
CN-1822861-A Stable radiopharmaceutical compositions and methods of preparation BRACCO IMAGING SPA (IT) 2006-08-23 CN claimed
EP-4393512-B1 COMPOSITION FOR PHARMACEUTICAL TABLET, PHARMACEUTICAL TABLET USING THE SAME, AND MANUFACTURING METHOD THEREOF MITSUBISHI CHEM CORP (JP) 2025-10-01 EP disclosed
EP-3603648-B1 COMPLEX OF NUCLEIC ACID MEDICINE AND MULTIBRANCHED LIPID SHIONOGI & CO (JP) 2025-09-17 EP disclosed
CN-114729004-B Heterocyclic compounds 日商泛美克斯股份有限公司 2025-06-03 CN disclosed
WO-2025105451-A1 SOLID PREPARATION 第一三共ヘルスケア株式会社 2025-05-22 WO disclosed
EP-0627218-A1 FAST SOLUBLE TABLET NIPPON SHINYAKU COMPANY, LIMITED (JP) 1994-12-07 EP disclosed
US-5368861-A Gastric preparation with sustained release NIPPON SHINYAKU CO., LTD. (JP) 1994-11-29 US disclosed
EP-0617960-A1 Use of pyridoxal derivatives for the manufacture of a medicament for the treatment of cataract Senju Pharmaceutical Co., Ltd. (JP) 1994-10-05 EP disclosed
EP-0497977-A1 GASTRIC PREPARATION NIPPON SHINYAKU COMPANY, LIMITED (JP) 1992-08-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250161255-A1 NEW THERAPY AND PREVENTION FOR SUPPRESSING AGING-RELATED DISORDERS INCLUDING SARCOPENIA MTPN, TNNC1, MSTN PTGS2 3901/4885ACE 174/4885PTGS1 2299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.