Hydrochloric Acid

Hydrochloric Acid

SCHEMBL890396

Cl.Cl.Cl.O=C(O)c1ccc(C(=O)O)c(C(=O)O)c1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA2 known ✓ P00918 1/20 0.50
▸ GAA known ✓ P10253 1/20 0.50
▸ PTGS2 known ✓ P35354 1/20 0.50
▸ KDM4E B2RXH2 3/20 0.67
▸ HSD17B10 Q99714 3/20 0.63
▸ CDC25A P30304 1/20 0.63
▸ CDC25B P30305 1/20 0.63
▸ POLB P06746 4/20 0.61
▸ L3MBTL1 Q9Y468 3/20 0.61
▸ TDP1 Q9NUW8 3/20 0.61
▸ TSHR P16473 2/20 0.52
▸ TP53 P04637 1/20 0.52
▸ CA12 O43570 1/20 0.50
▸ CA1 P00915 1/20 0.50
▸ MAPT P10636 1/20 0.50
▸ CA4 P22748 1/20 0.50
▸ CA6 P23280 1/20 0.50
▸ CA7 P43166 1/20 0.50
▸ CA9 Q16790 1/20 0.50
▸ CA14 Q9ULX7 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9043607 1.00 KDM4E (0.67) KDM4EHSD17B10CDC25ACDC25BPOLB
Hydrochloric Acid SCHEMBL10839755 1.00 KDM4E (0.67) KDM4EHSD17B10CDC25ACDC25BPOLB
Hydrochloric Acid SCHEMBL475975 1.00 KDM4E (0.67) KDM4EHSD17B10CDC25ACDC25BPOLB
Hydrochloric Acid SCHEMBL10839750 1.00 KDM4E (0.67) KDM4EHSD17B10CDC25ACDC25BPOLB
Hydrochloric Acid SCHEMBL15814393 0.98 KDM4E (0.64) KDM4EHSD17B10CDC25ACDC25BPOLB
SCHEMBL29350135 0.97 KDM4E (0.69) KDM4EHSD17B10CDC25ACDC25BPOLB
SCHEMBL30163040 0.97 KDM4E (0.69) KDM4EHSD17B10CDC25ACDC25BPOLB
SCHEMBL23861 0.97 KDM4E (0.69) KDM4EHSD17B10CDC25ACDC25BPOLB
SCHEMBL29899307 0.97 KDM4E (0.69) KDM4EHSD17B10CDC25ACDC25BPOLB
SCHEMBL23279 0.97 KDM4E (0.69) KDM4EHSD17B10CDC25ACDC25BPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104684973-A Flame-resistant polycarbonate film SABIC INNOVATIVE PLASTICS IP 2015-06-03 — — CN claimed
US-20110168631-A1 METHODS AND APPARATUSES FOR WATER FILTRATION USING POLYARYLETHER MEMBRANES GENERAL ELECTRIC COMPANY (US) 2011-07-14 — — US claimed
CN-100447178-C Process for preparing branched polycarbonate DOW GLOBAL TECHNOLOGIES INC (US) 2008-12-31 — — CN claimed
US-12570798-B2 Polyether compound and gas separation membrane ZEON CORPORATION (JP) 2026-03-10 — — US disclosed
US-20240335796-A1 THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME THE PENN STATE RESEARCH FOUNDATION 2024-10-10 — — US disclosed
US-12036515-B2 Thin-film composite membrane and methods of making and using the same THE PENN STATE RESEARCH FOUNDATION (PA) 2024-07-16 — — US disclosed
CN-118185272-A Polycarbonate composition and preparation method and application thereof 上海金发科技发展有限公司 2024-06-14 — — CN disclosed
CN-111094445-B Thermoplastic resin composition with enhanced ultraviolet resistance 英力士苯领集团股份公司 2023-12-19 — — CN disclosed
CN-108884307-B Articles of manufacture using impact modified melt polycarbonates 沙特基础工业全球技术公司 2023-11-21 — — CN disclosed
CN-111742011-B Polycarbonate compositions having improved chemical resistance, articles formed therefrom, and methods of making 高新特殊工程塑料全球技术有限公司 2023-06-23 — — CN disclosed
CN-112752786-B Polycarbonate compositions with improved oxidative stability and methods for preparing same SABIC环球技术有限责任公司 2023-06-09 — — CN disclosed
EP-0303076-A2 Polyester-polycarbonate compositions with favorable melt viscosity properties GENERAL ELECTRIC COMPANY (US) 1989-02-15 — — EP disclosed
US-4788251-A CONTAINING POLY(O-OR N-EPOXYALKYL SUBSTITUTED) CYCLIC AMIDE, IMIDE OR IMIDATE GENERAL ELECTRIC COMPANY (US) 1988-11-29 — — US disclosed
EP-0061782-B1 COMPOSITE SEMIPERMEABLE MEMBRANE AND PROCESS FOR PREPARATION THEREOF NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) 1987-06-24 — — EP disclosed
EP-0195497-A2 Catalyst component for olefin polymerization TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1986-09-24 — — EP disclosed
US-4612118-A Composite semipermeable membrane of polyamine and trianzine NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) 1986-09-16 — — US disclosed
EP-0061782-A2 Composite semipermeable membrane and process for preparation thereof NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) 1982-10-06 — — EP disclosed
US-4209610-A POLYETHYLENE TEREPHTHALATE, ANTISOILANTS, WATER AND OIL REPELLENCY MARES FRANK (US) 1980-06-24 — — US disclosed
US-4104300-A MOLYBDENUM CATALYST, COMPLEXING AGENT DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1978-08-01 — — US disclosed
US-4086209-A Novel nitrogen-containing aromatic polymers and process for their preparation TEIJIN LIMITED (JA) 1978-04-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240335796-A1 THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME PORCN, MLEC, FLOT1 CA2 3089/4885GAA 4229/4885PTGS2 1290/4885
US-12570798-B2 Polyether compound and gas separation membrane KCNE1, PARG, TRPA1 CA2 38/4885GAA 2674/4885PTGS2 2491/4885
US-12036515-B2 Thin-film composite membrane and methods of making and using the same PORCN, MLEC, FLOT1 CA2 3089/4885GAA 4229/4885PTGS2 1290/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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