Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 known ✓ | Q99720 | 1/20 | 0.41 |
| ▸ | MAOA known ✓ | P21397 | 1/20 | 0.39 |
| ▸ | S1PR2 known ✓ | O95136 | 1/20 | 0.39 |
| ▸ | S1PR4 known ✓ | O95977 | 1/20 | 0.39 |
| ▸ | S1PR1 known ✓ | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 known ✓ | Q99500 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | ADH7 | P40394 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19411953 | 0.98 | EPHX2 (0.47) | EPHX2FAAHCNR1CNR2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8900595 | 0.80 | EPHX2 (0.47) | EPHX2FAAHCNR1CNR2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL9725437 | 0.78 | EPHX2 (0.46) | EPHX2FAAHCNR1CNR2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL11150761 | 0.78 | EPHX2 (0.46) | EPHX2FAAHCNR1CNR2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8417309 | 0.78 | EPHX2 (0.46) | EPHX2FAAHCNR1CNR2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL2232233 | 0.78 | EPHX2 (0.46) | EPHX2FAAHCNR1CNR2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL28716627 | 0.78 | EPHX2 (0.46) | EPHX2FAAHCNR1CNR2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL356747 | 0.78 | EPHX2 (0.46) | EPHX2FAAHCNR1CNR2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL3299241 | 0.78 | EPHX2 (0.46) | EPHX2FAAHCNR1CNR2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8988138 | 0.77 | EPHX2 (0.45) | EPHX2FAAHCNR1CNR2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 256 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109983172-A | Antibacterial regenerated celulose fibre and preparation method thereof | 格拉姆工业有限公司 | 2019-07-05 | — | — | CN | claimed |
| CN-109152725-A | For handling the composition of keratin fiber | 莱雅公司 | 2019-01-04 | — | — | CN | claimed |
| CN-108024920-A | Include the liquid cosmetic composition and lip processing method of high non-volatile oil content | 莱雅公司 | 2018-05-11 | — | — | CN | claimed |
| CN-107427425-A | For adjusting the composition of hair | 莱雅公司 | 2017-12-01 | — | — | CN | claimed |
| CN-105492079-A | Composition comprising an aminosilicone, a cationic surfactant, an associative polymer and a thickener | OREAL | 2016-04-13 | — | — | CN | claimed |
| US-12233139-B2 | Oral care compositions containing a gel network phase | THE PROCTER & GAMBLE COMPANY (US) | 2025-02-25 | — | — | US | disclosed |
| EP-2533719-B1 | METHOD OF PRODUCING A COATED DENTAL FLOSS, AND DENTAL FLOSS | PROCTER & GAMBLE (US) | 2024-05-08 | — | — | EP | disclosed |
| US-20230104890-A1 | Oral Care Compositions Containing A Gel Network Phase | PROCTER & GAMBLE (US) | 2023-04-06 | — | — | US | disclosed |
| US-11517509-B2 | Oral care compositions containing a gel network phase | THE PROCTER & GAMBLE COMPANY (US) | 2022-12-06 | — | — | US | disclosed |
| US-11484487-B1 | Gingivitis gum serum | ROBELL RESEARCH, INC. (US) | 2022-11-01 | — | — | US | disclosed |
| US-20220257484-A1 | WHOLE MOUTH MALADOR CONTROL BY A COMBINATION OF ANTIBACTERIAL AND DEODORIZING AGENTS | PROCTER & GAMBLE (US) | 2022-08-18 | — | — | US | disclosed |
| EP-2424621-B1 | METHODS FOR IMPROVING TASTE AND ORAL CARE COMPOSITIONS WITH IMPROVED TASTE | PROCTER & GAMBLE (US) | 2021-11-03 | — | — | EP | disclosed |
| WO-2010019730-A1 | SYNTHESIS OF CYCLOHEXANE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | THE PROCTER & GAMBLE COMPANY (US) | 2010-02-18 | — | — | WO | disclosed |
| WO-2010004361-A2 | COMPOSITIONS AND METHODS FOR IMPROVING OVERALL TOOTH HEALTH AND APPEARANCE | THE PROCTER & GAMBLE COMPANY (US) | 2010-01-14 | — | — | WO | disclosed |
| US-20080247973-A1 | Compositions and Methods for Improving Overall Tooth Health and Appearance | THE PROCTER & GAMBLE COMPANY | 2008-10-09 | — | — | US | disclosed |
| CN-1917848-A | Sun-block cosmetic | SHISEIDO CO LTD (JP) | 2007-02-21 | — | — | CN | disclosed |
| EP-1708791-A1 | ORAL CARE COMPOSITIONS COMPRISING INCREASED BIOAVAILABLE LEVELS OF QUATERNARY AMMONIUM ANTIMICROBIALS | The Procter and Gamble Company (US) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005072693-A1 | ORAL CARE COMPOSITIONS COMPRISING INCREASED BIOAVAILABLE LEVELS OF QUATERNARY AMMONIUM ANTIMICROBIALS | THE PROCTER & GAMBLE COMPANY (US) | 2005-08-11 | — | — | WO | disclosed |
| US-20050169852-A1 | Oral care compositions comprising increased bioavailable levels of quaternary ammonium antimicrobials | THE PROCTER & GAMBLE COMPANY (US) | 2005-08-04 | — | — | US | disclosed |
| US-5405604-A | Oil in water emulsion containing microbiocidal quaternary ammonium compound, solvent/carrier, flavoring oil and water, for aqueous mouthwash concentrate to be diluted with water which breaks emulsion and turns mixture cloudy | THE PROCTER & GAMBLE COMPANY (US) | 1995-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12233139-B2 | Oral care compositions containing a gel network phase | FLNA, FLNB, FRG1 | SIGMAR1 1719/4885MAOA 4653/4885S1PR2 317/4885 |
| US-20230104890-A1 | Oral Care Compositions Containing A Gel Network Phase | FLNA, FLNB, FRG1 | SIGMAR1 1719/4885MAOA 4653/4885S1PR2 317/4885 |
| US-11517509-B2 | Oral care compositions containing a gel network phase | FLNA, FLNB, AP1G1 | SIGMAR1 1551/4885MAOA 4501/4885S1PR2 625/4885 |
| US-20220257484-A1 | WHOLE MOUTH MALADOR CONTROL BY A COMBINATION OF ANTIBACTERIAL AND DEODORIZING AGENTS | OR10J3, HDAC10, RPP30 | SIGMAR1 81/4885MAOA 2363/4885S1PR2 2090/4885 |
| US-20080247973-A1 | Compositions and Methods for Improving Overall Tooth Health and Appearance | ALPP, CHERP, CA3 | SIGMAR1 2178/4885MAOA 4310/4885S1PR2 2904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.