Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Ethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylamine SCHEMBL674041 | 1.00 | — | — | |
| Ethylamine SCHEMBL28837475 | 1.00 | — | — | |
| Ethylamine SCHEMBL3412953 | 1.00 | DNM1 (0.40) | DNM1ALDH1A1TSHRLMNAMAPT | |
| Ethylamine SCHEMBL30458185 | 1.00 | DNM1 (0.40) | DNM1ALDH1A1TSHRLMNAMAPT | |
| Ethylamine SCHEMBL1331914 | 1.00 | — | — | |
| Ethylamine SCHEMBL126107 | 1.00 | — | — | |
| Ethylamine SCHEMBL674042 | 1.00 | — | — | |
| Ethylamine SCHEMBL3412956 | 1.00 | — | — | |
| Ethylamine SCHEMBL23910301 | 0.94 | — | — | |
| Ethylamine SCHEMBL5507383 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11939336-B2 | Aryl triazole cages | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2024-03-26 | — | — | US | disclosed |
| WO-2023247519-A1 | A PROCESS FOR PREPARING HYDROXYPHENYL-1,3,5-TRIAZINE COMPOUNDS | BASF SE (DE) | 2023-12-28 | — | — | WO | disclosed |
| US-20210363150-A1 | ARYL TRIAZOLE CAGES | UNITED STATES DEPARTMENT OF ENERGY | 2021-11-25 | — | — | US | disclosed |
| US-8575293-B2 | Resin composition for optical material and optical material using the same | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2013-11-05 | — | — | US | disclosed |
| EP-2058346-B1 | RESIN COMPOSITION FOR OPTICAL MATERIAL AND OPTICAL MATERIAL USING THE SAME | MITSUBISHI GAS CHEMICAL CO (JP) | 2012-03-07 | — | — | EP | disclosed |
| EP-2374793-A1 | METHOD FOR PRODUCING ALKENYL MERCAPTAN | Sumitomo Chemical Company, Limited (JP) | 2011-10-12 | — | — | EP | disclosed |
| US-20110218363-A1 | METHOD FOR PRODUCING ALKENYL MERCAPTAN | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-09-08 | — | — | US | disclosed |
| US-20100004421-A1 | RESIN COMPOSITION FOR OPTICAL MATERIAL AND OPTICAL MATERIAL USING THE SAME | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2010-01-07 | — | — | US | disclosed |
| EP-2058346-A1 | RESIN COMPOSITION FOR OPTICAL MATERIAL AND OPTICAL MATERIAL USING THE SAME | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2009-05-13 | — | — | EP | disclosed |
| EP-0077542-B1 | PROCESS FOR PREPARING DIESTERS OF MALONIC ACID | UBE INDUSTRIES, LTD. (JP) | 1985-09-18 | — | — | EP | disclosed |
| US-4539423-A | FROM KETENE CARBON MONOXIDE AND ESTER OF NITROUS ACID; PLATINUM GROUP CATALYST | UBE INDUSTRIES LTD. (JP) | 1985-09-03 | — | — | US | disclosed |
| EP-0077542-A1 | Process for preparing diesters of malonic acid | UBE INDUSTRIES, LTD. (JP) | 1983-04-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11939336-B2 | Aryl triazole cages | CAT, SOD1, SOD3 | DNM1 4197/4885ALDH1A1 2562/4885TSHR 978/4885 |
| US-20110218363-A1 | METHOD FOR PRODUCING ALKENYL MERCAPTAN | TST, MPST, HACL2 | DNM1 4656/4885ALDH1A1 79/4885TSHR 2601/4885 |
| US-20210363150-A1 | ARYL TRIAZOLE CAGES | CAT, SOD1, SOD3 | DNM1 4197/4885ALDH1A1 2562/4885TSHR 978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.