Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL490834 | 0.99 | CYP1A2 (0.63) | CYP1A2CYP2D6 | |
| SCHEMBL29245298 | 0.90 | CYP1A2 (0.55) | CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL1850622 | 0.88 | CYP1A2 (0.44) | CYP1A2CYP2D6 | |
| SCHEMBL2026927 | 0.86 | CYP1A2 (0.45) | CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL28461388 | 0.85 | CYP1A2 (0.56) | CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL28414077 | 0.84 | CYP1A2 (0.55) | CYP1A2CYP2D6 | |
| SCHEMBL29245299 | 0.84 | CYP1A2 (0.58) | CYP1A2CYP2D6 | |
| SCHEMBL4362792 | 0.81 | CYP1A2 (0.38) | CYP1A2CYP2D6 | |
| Methylpyrrolidone SCHEMBL23037250 | 0.80 | CYP1A2 (0.56) | CYP1A2CYP2D6 | |
| Methyl Alcohol SCHEMBL29215793 | 0.80 | CYP1A2 (0.88) | CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 357 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118347993-A | Ag@EuW based10Preparation of carbohydrate antigen 19-9 (CA 19-9) of PEI | 济南大学 | 2024-07-16 | — | — | CN | claimed |
| CN-118290611-A | Ethylene glycol chitosan-TK-doxorubicin copolymer and polymerization method and application thereof | 湖州师范学院 | 2024-07-05 | — | — | CN | claimed |
| CN-118267522-A | Nanometer liposome crosslinked self-anti-inflammatory polysaccharide injectable hydrogel and preparation method and application thereof | 天津大学 | 2024-07-02 | — | — | CN | claimed |
| CN-118252986-A | Method for preparing anticoagulation coating on surface of substrate and blood contact medical device | 上海发微医用材料有限公司 | 2024-06-28 | — | — | CN | claimed |
| CN-118217419-A | Nanometer drug delivery system for overcoming tumor multidrug resistance and preparation method thereof | 山东理工大学 | 2024-06-21 | — | — | CN | claimed |
| CN-115343280-B | Colorimetric detection test paper for cellulose membrane-based organophosphorus pesticide and preparation method and application thereof | 武汉工程大学 | 2024-06-18 | — | — | CN | claimed |
| CN-118026985-A | Continuous foaming type concrete air entraining agent and preparation method thereof | 江苏奥莱特新材料股份有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-114249909-B | Micro-nano magnetic polymer microsphere with surface topological structure and preparation method thereof | 中国科学院理化技术研究所 | 2024-05-03 | — | — | CN | claimed |
| CN-117919447-A | PH and thermal response type iron nano-glue and preparation method and application thereof | 中国药科大学 | 2024-04-26 | — | — | CN | claimed |
| CN-117783239-A | MXene-based electrochemical biosensor array and preparation method and application thereof | 江苏大学 | 2024-03-29 | — | — | CN | claimed |
| US-10288569-B2 | Hydrogel, preparation method thereof, and pH sensor comprising the same | INDUSTRY-ACADEMIC CORPORATION FOUNDATION YONSEI UNIVERSITY (KR) | 2019-05-14 | — | — | US | claimed |
| EP-3241852-B1 | HYALURONIC ACID-BASED AMPHIPHILIC POLYMER, PREPARATION METHOD AND APPLICATION THEREOF | BRIGHTGENE BIO MEDICAL TECH CO LTD (CN) | 2018-10-17 | — | — | EP | claimed |
| WO-2018109204-A1 | PROCESS FOR THE PREPARATION OF (S)-2-((2-((S)-4-(DIFLUOROMETHYL)-2-OXOOXAZOLIDIN-3-YL)-5,6-DIHYDROBENZO[F]IMIDAZO[1,2-D][1,4]OXAZEPIN-9-YL)AMINO) PROPANAMIDE | F. HOFFMANN-LA ROCHE AG (CH) | 2018-06-21 | — | — | WO | claimed |
| US-20180092858-A1 | Hyaluronic Acid-Based Amphiphilic Polymer, Preparation Method and Application Thereof | BRIGHTGENE BIO-MEDICAL TECHNOLOGY CO., LTD. (CN) | 2018-04-05 | — | — | US | claimed |
| EP-3241852-A1 | HYALURONIC ACID-BASED AMPHIPHILIC POLYMER, PREPARATION METHOD AND APPLICATION THEREOF | BrightGene Bio-Medical Technology Co., Ltd. (CN) | 2017-11-08 | — | — | EP | claimed |
| US-20170146459-A1 | HYDROGEL, PREPARATION METHOD THEREOF, AND pH SENSOR COMPRISING THE SAME | INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIVERSITY (KR) | 2017-05-25 | — | — | US | claimed |
| US-20150362437-A1 | HYDROGEL, PREPARATION METHOD THEREOF, AND pH SENSOR COMPRISING THE SAME | INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIVERSITY (KR) | 2015-12-17 | — | — | US | claimed |
| US-7288661-B2 | Process for the synthesis of (2S,3aS,7aS)-1-[(S)-alanyl]-octahydro-1H-indole-2-carboxylic acid compounds and application in the synthesis of perindopril | LES LABORATOIRES SERVIER (FR) | 2007-10-30 | — | — | US | claimed |
| US-20070123581-A1 | Process for the synthesis of (2s, 3as, 7as)-1-[(s)-alanyl]-octahydro-1h-indole-2-carboxylic acid compounds and application in the synthesis of perindopril | LES LABORATOIRES SERVIER (FR) | 2007-05-31 | — | — | US | claimed |
| US-20070093663-A1 | Process for the synthesis of perindopril and pharmaceutically acceptable salts thereof. | LES LABORATOIRES SERVIER (FR) | 2007-04-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180092858-A1 | Hyaluronic Acid-Based Amphiphilic Polymer, Preparation Method and Application Thereof | CD44, HCAR1, ASGR1 | CYP1A2 3687/4885CYP2D6 2761/4885 |
| US-20070093663-A1 | Process for the synthesis of perindopril and pharmaceutically acceptable salts thereof. | QDPR, REN, ACE | CYP1A2 56/4885CYP2D6 5/4885 |
| US-20070123581-A1 | Process for the synthesis of (2s, 3as, 7as)-1-[(s)-alanyl]-octahydro-1h-indole-2-carboxylic acid compounds and application in the synthesis of perindopril | CYP2S1, TPH1, AGTR1 | CYP1A2 23/4885CYP2D6 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.