Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.53 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 0.53 |
| ▸ | HTR1A known ✓ | P08908 | 1/20 | 0.53 |
| ▸ | CHRM5 known ✓ | P08912 | 1/20 | 0.53 |
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.53 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.53 |
| ▸ | ADRA2B known ✓ | P18089 | 1/20 | 0.53 |
| ▸ | ADRA2C known ✓ | P18825 | 1/20 | 0.53 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.53 |
| ▸ | DRD1 known ✓ | P21728 | 1/20 | 0.53 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.53 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.53 |
| ▸ | HRH2 known ✓ | P25021 | 1/20 | 0.53 |
| ▸ | ADRA1D known ✓ | P25100 | 1/20 | 0.53 |
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.53 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.53 |
| ▸ | DRD3 known ✓ | P35462 | 1/20 | 0.53 |
| ▸ | SCN1A known ✓ | P35498 | 1/20 | 0.53 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.53 |
| ▸ | KCNH2 known ✓ | Q12809 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29382410 | 1.00 | ADORA2A (0.63) | ADORA2AMEN1KMT2ATDP1MBNL1 | |
| SCHEMBL29903944 | 0.99 | ADORA2A (0.64) | ADORA2AMEN1KMT2ATDP1MBNL1 | |
| SCHEMBL8011648 | 0.99 | ADORA2A (0.64) | ADORA2AMEN1KMT2ATDP1MBNL1 | |
| SCHEMBL18163841 | 0.88 | ADORA2A (0.80) | ADORA2AMEN1KMT2ATDP1MBNL1 | |
| SCHEMBL12057934 | 0.87 | ADORA2A (0.78) | ADORA2AMEN1KMT2ATDP1MBNL1 | |
| Acridine Dimer SCHEMBL31494050 | 0.87 | ADORA2A (0.78) | ADORA2AMEN1KMT2ATDP1MBNL1 | |
| Acridine Dimer SCHEMBL31329233 | 0.87 | ADORA2A (0.78) | ADORA2AMEN1KMT2ATDP1MBNL1 | |
| SCHEMBL7880398 | 0.87 | MEN1 (0.79) | ADORA2AMEN1KMT2ATDP1MBNL1 | |
| SCHEMBL28305867 | 0.86 | GSR (0.48) | ADORA2AMEN1KMT2ATDP1MBNL1 | |
| SCHEMBL18163852 | 0.86 | ADORA2A (0.80) | ADORA2AMEN1KMT2ATDP1MBNL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 434 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019077459-A1 | PAPAYA WITH NOVEL TRAITS AND METHODS FOR PRODUCING SUCH PAPAYA PLANTS | BENCHBIO PVT. LTD. (IN) | 2019-04-25 | — | — | WO | claimed |
| US-20190110418-A1 | PAPAYA WITH NOVEL TRAITS AND METHODS FOR PRODUCING SUCH PAPAYA PLANTS | HORTIGENETICS RESEARCH (S.E. ASIA) LTD. (TH) | 2019-04-18 | — | — | US | claimed |
| US-20040053236-A1 | Reverse genetic strategy for identifying functional mutations in genes of known sequences | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-03-18 | — | — | US | claimed |
| WO-2001075167-A1 | REVERSE GENETIC STRATEGY FOR IDENTIFYING FUNCTIONAL MUTATIONS IN GENES OF KNOWN SEQUENCE | FRED HUTCHINSON CANCER RESEARCH CENTER (US) | 2001-10-11 | — | — | WO | claimed |
| US-12610956-B2 | Agricultural compositions comprising remodeled nitrogen fixing microbes | PIVOT BIO, INC. (US) | 2026-04-28 | — | — | US | disclosed |
| US-20260107948-A1 | AGRICULTURAL COMPOSITIONS COMPRISING REMODELED NITROGEN FIXING MICROBES | PIVOT BIO INC (US) | 2026-04-23 | — | — | US | disclosed |
| EP-2935588-B1 | TOBACCO SPECIFIC NITROSAMINE REDUCTION IN PLANTS | PHILIP MORRIS PRODUCTS SA (CH) | 2026-03-25 | — | — | EP | disclosed |
| US-20260041099-A1 | AGRICULTURAL COMPOSITIONS COMPRISING REMODELED NITROGEN FIXING MICROBES | PIVOT BIO INC (US) | 2026-02-12 | — | — | US | disclosed |
| US-12516337-B2 | Modulating amino acid content in a plant | PHILIP MORRIS PRODUCTS S.A. (CH) | 2026-01-06 | — | — | US | disclosed |
| US-12497342-B2 | Methods and compositions for improving plant traits | PIVOT BIO, INC. (US) | 2025-12-16 | — | — | US | disclosed |
| US-20250376424-A1 | TEMPORALLY AND SPATIALLY TARGETED DYNAMIC NITROGEN DELIVERY BY REMODELED MICROBES | PIVOT BIO, INC. (US) | 2025-12-11 | — | — | US | disclosed |
| US-20250369878-A1 | MEASUREMENT OF NITROGEN FIXATION AND INCORPORATION | PIVOT BIO INC (US) | 2025-12-04 | — | — | US | disclosed |
| WO-2005046314-A2 | TOMATOES HAVING ALTERED ACID INVERTASE ACTIVITY DUE TO NON-TRANSGENIC ALTERATIONS IN ACID INVERTASE GENES | ARCADIA BIOSCIENCES, INC. (US) | 2005-05-26 | — | — | WO | disclosed |
| WO-2005046309-A2 | TOMATOES HAVING REDUCED POLYGALACTURONASE ACTIVITY CAUSED BY NON-TRANSGENIC MUTATIONS IN THE POLYGALACTURONASE GENE | ANAWAH, INC. (US) | 2005-05-26 | — | — | WO | disclosed |
| US-20040250322-A1 | Tomatoes having reduced polygalacturonase activity caused by non-transgenic mutations in the polygalacturonase gene | ANAWAH, INC. | 2004-12-09 | — | — | US | disclosed |
| US-20040053236-A1 | Reverse genetic strategy for identifying functional mutations in genes of known sequences | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-03-18 | — | — | US | disclosed |
| WO-2001075167-A1 | REVERSE GENETIC STRATEGY FOR IDENTIFYING FUNCTIONAL MUTATIONS IN GENES OF KNOWN SEQUENCE | FRED HUTCHINSON CANCER RESEARCH CENTER (US) | 2001-10-11 | — | — | WO | disclosed |
| US-5541108-A | Gluconobacter oxydans strains | HOFFMANN-LA ROCHE INC. (US) | 1996-07-30 | — | — | US | disclosed |
| EP-0213591-B1 | PROCESS FOR THE MANUFACTURE OF KETO GULONIC ACID | F. HOFFMANN-LA ROCHE AG (CH) | 1992-03-25 | — | — | EP | disclosed |
| EP-0213591-A2 | Process for the manufacture of keto gulonic acid | F. HOFFMANN-LA ROCHE AG (CH) | 1987-03-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260041099-A1 | AGRICULTURAL COMPOSITIONS COMPRISING REMODELED NITROGEN FIXING MICROBES | AMPD2, DDC, INMT | CHRM2 860/4885CHRM4 1961/4885HTR1A 2677/4885 |
| US-12610956-B2 | Agricultural compositions comprising remodeled nitrogen fixing microbes | GLUL, IPMK, GNMT | CHRM2 3743/4885CHRM4 4055/4885HTR1A 4433/4885 |
| US-20260107948-A1 | AGRICULTURAL COMPOSITIONS COMPRISING REMODELED NITROGEN FIXING MICROBES | GLUL, IPMK, GNMT | CHRM2 3743/4885CHRM4 4055/4885HTR1A 4433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.