Tetrabuthylammonium

Tetrabuthylammonium

SCHEMBL193669

CCCC[N+](CCCC)(CCCC)CCCC.O=C([O-])[O-].[H+]

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Tetrabuthylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC22A1 O15245 3/20 0.63
SLC22A2 O15244 1/20 0.55
ALDH1A1 P00352 1/20 0.50
TP53 P04637 1/20 0.50
CYP3A4 P08684 1/20 0.50
ALOX15 P16050 1/20 0.50
TSHR P16473 1/20 0.50
ALOX12 P18054 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
HIF1A Q16665 1/20 0.50
HSD17B10 Q99714 1/20 0.50
CES2 O00748 4/20 0.48
CES1 P23141 4/20 0.48
DNM1 Q05193 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrabuthylammonium SCHEMBL106861 0.97 SLC22A1 (0.67) SLC22A1SLC22A2ALDH1A1TP53CYP3A4
Tetrabuthylammonium SCHEMBL16343940 0.95 SLC22A1 (0.63) SLC22A1SLC22A2ALDH1A1TP53CYP3A4
Tetrabuthylammonium SCHEMBL21372575 0.95 SLC22A1 (0.63) SLC22A1SLC22A2ALDH1A1TP53CYP3A4
Bicarbonate SCHEMBL28716225 0.95 SLC22A1 (0.63) SLC22A1SLC22A2ALDH1A1TP53CYP3A4
Tetrabuthylammonium SCHEMBL3488443 0.92 SLC22A1 (0.60) SLC22A1SLC22A2ALDH1A1TP53CYP3A4
Tetrabuthylammonium SCHEMBL3488441 0.92 SLC22A1 (0.60) SLC22A1SLC22A2ALDH1A1TP53CYP3A4
Tetrabuthylammonium SCHEMBL16093909 0.92 SLC22A1 (0.60) SLC22A1SLC22A2ALDH1A1TP53CYP3A4
Tetrabuthylammonium SCHEMBL5786096 0.92 SLC22A1 (0.60) SLC22A1SLC22A2ALDH1A1TP53CYP3A4
Tetrabuthylammonium SCHEMBL5786097 0.92 SLC22A1 (0.60) SLC22A1SLC22A2ALDH1A1TP53CYP3A4
Bicarbonate SCHEMBL20984990 0.92 SLC22A1 (0.65) SLC22A1SLC22A2ALDH1A1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250162993-A1 SYNTHESIS OF THE RADIOLABELED PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA) INHIBITOR [18F]DCFPYL THE JOHNS HOPKINS UNIVERSITY 2025-05-22 US claimed
EP-3481804-B1 IMPROVED SYNTHESIS OF THE RADIOLABELED PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA) INHIBITOR [18F]DCFPyL UNIV JOHNS HOPKINS (US) 2024-11-27 EP claimed
US-11851407-B2 Synthesis of the radiolabeled prostate-specific membrane antigen (PSMA) inhibitor [18F]DCFPYL THE JOHNS HOPKINS UNIVERSTY (US) 2023-12-26 US claimed
US-20220055991-A1 SYNTHESIS OF THE RADIOLABELED PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA) INHIBITOR [18F]DCFPYL THE JOHNS HOPKINS UNIVERSTY 2022-02-24 US claimed
EP-3481437-B1 PRECURSORS FOR RADIOFLUORINATION ABX ADVANCED BIOCHEMICAL COMPOUNDS GMBH (DE) 2022-01-26 EP claimed
US-20210140096-A1 GRAPHENE MATERIAL COATING AND PREPARATION METHOD THEREOF, AIR FILTRATION DEVICE AND SYSTEM HUBEI HIGHLAND GRAPHENE TECHNOLOGY CO., LTD. (CN) 2021-05-13 US claimed
US-10759760-B2 Precursors for radiofluorination ABX ADVANCED BIOCHEMICAL COMPOUNDS GMBH (DE) 2020-09-01 US claimed
CN-111362828-A A kind of18F-labeled fluoropropionylated ornithine as well as preparation method and application thereof 山西医科大学 2020-07-03 CN claimed
US-20200080979-A1 METHOD AND DEVICES FOR THE SPECTROPHOTOMETRIC DETERMINATION OF RESIDUAL PHASE TRANSFER CATALYST IN A PET RADIOPHARMACEUTICAL DOSE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2020-03-12 US claimed
US-20190263756-A1 PRECURSORS FOR RADIOFLUORINATION ABX ADVANCED BIOCHEMICAL COMPOUNDS GMBH (DE) 2019-08-29 US claimed
US-20190177275-A1 IMPROVED SYNTHESIS OF THE RADIOLABELED PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA) INHIBITOR [18F]DCFPYL NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2019-06-13 US claimed
EP-3481437-A1 PRECURSORS FOR RADIOFLUORINATION ABX Advanced Biochemical Compounds GmbH (DE) 2019-05-15 EP claimed
EP-3481804-A1 IMPROVED SYNTHESIS OF THE RADIOLABELED PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA) INHIBITOR [18F]DCFPyL The Johns Hopkins University (US) 2019-05-15 EP claimed
WO-2017214470-A1 IMPROVED SYNTHESIS OF THE RADIOLABELED PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA) INHIBITOR [18F]DCFPyL THE JOHNS HOPKINS UNIVERSITY (US) 2017-12-14 WO claimed
EP-2336114-B1 PROCESS FOR THE SYNTHESIS OF L-3,4 DIHYDROXY-6-[18F]FLUORO-PHENYLALANINE AND 2-[18F]FLUOR-L-TYROSINE AND THEIR ALPHA-METHYLATED DERIVATIVES STARTING FROM A PRECURSOR FORSCHUNGSZENTRUM JUELICH GMBH (DE) 2013-04-17 EP claimed
US-6919475-B2 Protected tyrosine derivatives, method for the production thereof and use of the same for producing o-(2-[18f]-fluoroethyl)-l-tyrosine Forschungszentrum Jülich GmbH (DE) 2005-07-19 US claimed
EP-1392650-B1 PROTECTED TYROSINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR PRODUCING O-(2- ?18 F]-FLUOROETHYL)-L-TYROSINE FORSCHUNGSZENTRUM JUELICH GMBH (DE) 2005-03-02 EP claimed
US-20040192954-A1 Protected tyrosine derivatives, method for the production thereof and use of the same for producing o-(2-[18f]-fluoroethyl)-l-tyrosine FORSCHUNGSZENTRUM GMBH (DE) 2004-09-30 US claimed
US-5693599-A Flux washing agent MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1997-12-02 US claimed
US-20260124326-A1 USE OF CYCLODEXTRINS AS A RADIOSTABILIZER GE HEALTHCARE LTD (GB) 2026-05-07 US disclosed
EP-4039760-B1 POLISHING COMPOSITION FUJIMI INC (JP) 2026-04-08 EP disclosed
EP-4717720-A1 CATALYST COMPOSITION, BLOCKED POLYISOCYANATE COMPOSITION, COATING MATERIAL COMPOSITION, COATING FILM, AND METHOD FOR FORMING COATING FILM Tosoh Corporation (JP) 2026-04-01 EP disclosed
US-12527884-B2 Use of cyclodextrins as a radiostabilizer GE HEALTHCARE LIMITED (GB) 2026-01-20 US disclosed
EP-4633683-A1 CYCLOOCTENE COMPOSITIONS AND USES THEREOF Biogen MA Inc. (US) 2025-10-22 EP disclosed
US-20250312494-A1 METHOD FOR PREPARING AN [18F] RADIOLABELLED COMPOUND WITH LOW WATER CONTENT DURING LABELLING STEP GE HEALTHCARE INC (GB) 2025-10-09 US disclosed
US-20250162993-A1 SYNTHESIS OF THE RADIOLABELED PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA) INHIBITOR [18F]DCFPYL THE JOHNS HOPKINS UNIVERSITY 2025-05-22 US disclosed
WO-2025080839-A1 IMPROVED RADIOSYNTHESIS OF 18F-LABELED NUCLEOSIDE ANALOGUES UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2025-04-17 WO disclosed
EP-3774698-B1 SOLID PHASE EXTRACTION GE HEALTHCARE LTD (GB) 2025-02-26 EP disclosed
US-20250041859-A1 SOLID PHASE EXTRACTION GE HEALTHCARE LIMITED (GB) 2025-02-06 US disclosed
EP-4497477-A2 IMPROVED SYNTHESIS OF THE RADIOLABELED PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA) INHIBITOR [18F]DCFPYL The Johns Hopkins University (US) 2025-01-29 EP disclosed
WO-2024262553-A1 CATALYST COMPOSITION, BLOCKED POLYISOCYANATE COMPOSITION, COATING MATERIAL COMPOSITION, COATING FILM, AND METHOD FOR FORMING COATING FILM 東ソー株式会社 2024-12-26 WO disclosed
US-12162009-B2 Solid phase purification GE HEALTHCARE LIMITED (GB) 2024-12-10 US disclosed
EP-3481804-B1 IMPROVED SYNTHESIS OF THE RADIOLABELED PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA) INHIBITOR [18F]DCFPyL UNIV JOHNS HOPKINS (US) 2024-11-27 EP disclosed
US-20240366808-A1 METHOD FOR PREPARING AN [18F] RADIOLABELLED COMPOUND WITH LOW WATER CONTENT DURING LABELLING STEP GE HEALTHCARE LIMITED (GB) 2024-11-07 US disclosed
US-20240350683-A1 PREPARATION OF A PH-ADJUSTED ASCORBIC ACID SOLUTION GE HEALTHCARE LIMITED (GB) 2024-10-24 US disclosed
WO-2024202500-A1 BLOCKED POLYISOCYANATE COMPOSITION, CURING AGENT FOR AQUEOUS COATING, AQUEOUS COATING COMPOSITION, AND COATING FILM 東ソー株式会社 2024-10-03 WO disclosed
EP-4404981-A1 RADIOPHARMACEUTICAL COMPLEX FOR IMAGING AND/OR LOCALIZING PSMA POSITIVE CELLS Scogif S.r.l. (IT) 2024-07-31 EP disclosed
WO-2024130105-A1 CYCLOOCTENE COMPOSITIONS AND USES THEREOF BIOGEN MA INC. (US) 2024-06-20 WO disclosed
EP-4355368-A1 PREPARATION OF A PH-ADJUSTED ASCORBIC ACID SOLUTION GE Healthcare Limited (GB) 2024-04-24 EP disclosed
EP-4355715-A1 METHOD FOR PREPARING AN [18F] RADIOLABELLED COMPOUND WITH LOW WATER CONTENT DURING LABELLING STEP GE Healthcare Limited (GB) 2024-04-24 EP disclosed
US-11851407-B2 Synthesis of the radiolabeled prostate-specific membrane antigen (PSMA) inhibitor [18F]DCFPYL THE JOHNS HOPKINS UNIVERSTY (US) 2023-12-26 US disclosed
CN-110461802-B Method for producing flutemetamol 通用电气健康护理有限公司 2023-05-09 CN disclosed
US-20230120841-A1 CASSETTE FOR STABILISED RADIOLABELLING REACTION GE HEALTHCARE LTD (GB) 2023-04-20 US disclosed
WO-2023047319-A1 RADIOPHARMACEUTICAL COMPLEX FOR IMAGING AND/OR LOCALIZING PSMA POSITIVE CELLS SCOGIF S.R.L. (IT) 2023-03-30 WO disclosed
US-11565257-B2 Stabilized radiolabelling reaction GE HEALTHCARE LIMITED (GB) 2023-01-31 US disclosed
US-20220409752-A1 USE OF CYCLODEXTRINS AS A RADIOSTABILIZER GE HEALTHCARE LIMITED (GB) 2022-12-29 US disclosed
WO-2022263592-A1 PREPARATION OF A PH-ADJUSTED ASCORBIC ACID SOLUTION GE HEALTHCARE LIMITED (GB) 2022-12-22 WO disclosed
WO-2022263594-A1 METHOD FOR PREPARING AN [18F] RADIOLABELLED COMPOUND WITH LOW WATER CONTENT DURING LABELLING STEP GE HEALTHCARE LIMITED (GB) 2022-12-22 WO disclosed
EP-3774697-B1 STABILISED RADIOLABELLING REACTION GE HEALTHCARE LTD (GB) 2022-11-23 EP disclosed
US-20220306867-A1 MODIFIED COATING SUBSTANCES BASED ON RMA BINDERS WITH IMPROVED ADHESION ON METAL SUBSTRATES MANKIEWICZ GEBR. & CO. (GMBH & CO. KG) (DE) 2022-09-29 US disclosed
EP-4048323-A1 USE OF CYCLODEXTRINS AS A RADIOSTABILIZER GE Healthcare Limited (GB) 2022-08-31 EP disclosed
EP-4039760-A1 POLISHING COMPOSITION Fujimi Incorporated (JP) 2022-08-10 EP disclosed
CN-114450376-A Polishing composition 福吉米株式会社 2022-05-06 CN disclosed
US-20220118117-A1 MODULATORS OF METABOTROPIC GLUTAMATE RECEPTOR 4 MASSACHUSETTS GEN HOSPITAL (US) 2022-04-21 US disclosed
EP-3983471-A1 MODIFIED COATING SUBSTANCES BASED ON RMA BINDERS WITH IMPROVED ADHESION ON METAL SUBSTRATES Mankiewicz Gebr. & Co. GmbH & Co. KG (DE) 2022-04-20 EP disclosed
US-20220055991-A1 SYNTHESIS OF THE RADIOLABELED PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA) INHIBITOR [18F]DCFPYL THE JOHNS HOPKINS UNIVERSTY 2022-02-24 US disclosed
US-20210322582-A1 RADIOACTIVE IMIDAZOTHIADIAZOLE DERIVATIVE COMPOUND NIHON MEDI-PHYSICS CO., LTD. (JP) 2021-10-21 US disclosed
US-11078166-B2 Triazole conjugated ureas, thioureas, carbamates, and reversed carbamates for PSMA-targeted imaging agents and uses thereof THE JOHNS HOPKINS UNIVERSITY (US) 2021-08-03 US disclosed
EP-3845541-A1 RADIOACTIVE IMIDAZOTHIADIAZOLE DERIVATIVE COMPOUND Nihon Medi-Physics Co., Ltd (JP) 2021-07-07 EP disclosed
US-11053200-B2 Precursors for radiofluorination ABX ADVANCED BIOCHEMICAL COMPOUNDS GMBH (DE) 2021-07-06 US disclosed
EP-2994169-B1 LABELLED CARBOXYLIC ACIDS AND THEIR USES IN MOLECULAR IMAGING CANCER RESEARCH TECH LTD (GB) 2021-06-23 EP disclosed
US-20210140096-A1 GRAPHENE MATERIAL COATING AND PREPARATION METHOD THEREOF, AIR FILTRATION DEVICE AND SYSTEM HUBEI HIGHLAND GRAPHENE TECHNOLOGY CO., LTD. (CN) 2021-05-13 US disclosed
EP-3589607-B1 A PROCESS FOR PRODUCING FLUTEMETAMOL GE HEALTHCARE LTD (GB) 2021-05-05 EP disclosed
WO-2021078814-A1 USE OF CYCLODEXTRINS AS A RADIOSTABILIZER GE HEALTHCARE LIMITED (GB) 2021-04-29 WO disclosed
US-10947197-B2 Synthesis of the radiolabeled prostate-specific membrane antigen (PSMA) inhibitor [18F]DCFPyL THE JOHNS HOPKINS UNIVERSITY (US) 2021-03-16 US disclosed
EP-3774697-A1 STABILISED RADIOLABELLING REACTION GE Healthcare Limited (GB) 2021-02-17 EP disclosed
EP-3774698-A1 SOLID PHASE EXTRACTION GE Healthcare UK Limited (GB) 2021-02-17 EP disclosed
CN-112286000-A Composition for forming silicon-containing resist underlayer film and pattern forming method 信越化学工业株式会社 2021-01-29 CN disclosed
US-20210023558-A1 SOLID PHASE EXTRACTION GE HEALTHCARE LIMITED (GB) 2021-01-28 US disclosed
US-20210017098-A1 STABILISED RADIOLABELLING REACTION GE HEALTHCARE LIMITED (GB) 2021-01-21 US disclosed
US-10894779-B2 Process for producing flutametamol GE HEALTHCARE LIMITED (GB) 2021-01-19 US disclosed
US-10876007-B2 Coating systems, use thereof for coating components and thus coated components for wind power plants MANKIEWICZ GEBR. & CO. GMBH & CO. KG (DE) 2020-12-29 US disclosed
US-10870763-B2 Coating systems, use thereof for coating components and thus coated components for agricultural and construction machines MANKIEWICZ GEBR. & CO. GMBH & CO. KG (DE) 2020-12-22 US disclosed
US-10821194-B2 Labelled carboxylic acids and their uses in molecular imaging Cancer Research Technologies Limited (GB) 2020-11-03 US disclosed
CN-111856882-A Composition for forming silicon-containing resist underlayer film and pattern forming method 信越化学工业株式会社 2020-10-30 CN disclosed
US-10759760-B2 Precursors for radiofluorination ABX ADVANCED BIOCHEMICAL COMPOUNDS GMBH (DE) 2020-09-01 US disclosed
US-10738196-B2 Coating systems, use thereof for coating components and components coated therewith for rail vehicles and aircrafts MANKIEWICZ GEBR. & CO. GMBH & CO. KG (DE) 2020-08-11 US disclosed
CN-111458980-A Composition for forming silicon-containing resist underlayer film and pattern forming method 信越化学工业株式会社 2020-07-28 CN disclosed
CN-111423587-A Thermosetting silicon-containing compound, composition for forming silicon-containing film, and method for forming pattern 信越化学工业株式会社 2020-07-17 CN disclosed
WO-2020146515-A1 MODULATORS OF METABOTROPIC GLUTAMATE RECEPTOR 4 THE GENERAL HOSPITAL CORPORATION (US) 2020-07-16 WO disclosed
CN-111208710-A Iodine-containing thermosetting silicon-containing material, resist underlayer film-forming composition for extreme ultraviolet lithography containing the same, and pattern formation method 信越化学工业株式会社 2020-05-29 CN disclosed
US-20200165204-A1 PRECURSORS FOR RADIOFLUORINATION ABX ADVANCED BIOCHEMICAL COMPOUNDS GMBH (DE) 2020-05-28 US disclosed
US-20200080979-A1 METHOD AND DEVICES FOR THE SPECTROPHOTOMETRIC DETERMINATION OF RESIDUAL PHASE TRANSFER CATALYST IN A PET RADIOPHARMACEUTICAL DOSE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2020-03-12 US disclosed
US-20200062724-A1 A PROCESS FOR PRODUCING FLUTAMETAMOL INTEGRITY IMPLANTS INC. 2020-02-27 US disclosed
US-10472338-B2 Method for producing [18F]flutemetamol GE HEALTHCARE LIMITED (GB) 2019-11-12 US disclosed
WO-2019185932-A1 STABILISED RADIOLABELLING REACTION GE HEALTHCARE LIMITED (GB) 2019-10-03 WO disclosed
WO-2019185933-A1 SOLID PHASE EXTRACTION GE HEALTHCARE LIMITED (GB) 2019-10-03 WO disclosed
US-20190263756-A1 PRECURSORS FOR RADIOFLUORINATION ABX ADVANCED BIOCHEMICAL COMPOUNDS GMBH (DE) 2019-08-29 US disclosed
US-10392344-B2 Method for preparing fluorine-18 eluent with adjusted PH, and method for labelling fluorine-18 using same THE ASAN FOUNDATION (KR) 2019-08-27 US disclosed
US-20190225589-A1 TRIAZOLE CONJUGATED UREAS, THIOUREAS, CARBAMATES, AND REVERSED CARBAMATES FOR PSMA-TARGETED IMAGING AGENTS AND USES THEREOF THE JOHNS HOPKINS UNIVERSITY 2019-07-25 US disclosed
US-20190184039-A1 LABELLED CARBOXYLIC ACIDS AND THEIR USES IN MOLECULAR IMAGING IMPERIAL INNOVATIONS LIMITED (GB) 2019-06-20 US disclosed
US-20190177275-A1 IMPROVED SYNTHESIS OF THE RADIOLABELED PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA) INHIBITOR [18F]DCFPYL NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2019-06-13 US disclosed
US-20190151483-A1 METHODS OF MAKING 18F-LABELED PRECURSORS AND PEPTIDES, LABELED C-MET BINDING PEPTIDES, AND METHODS OF USE THEREOF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 2019-05-23 US disclosed
EP-3481804-A1 IMPROVED SYNTHESIS OF THE RADIOLABELED PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA) INHIBITOR [18F]DCFPyL The Johns Hopkins University (US) 2019-05-15 EP disclosed
EP-3481437-A1 PRECURSORS FOR RADIOFLUORINATION ABX Advanced Biochemical Compounds GmbH (DE) 2019-05-15 EP disclosed
US-20190055207-A1 Method for Producing Flutemetamol GE HEALTHCARE LIMITED (GB) 2019-02-21 US disclosed
WO-2018158137-A1 A PROCESS FOR PRODUCING FLUTEMETAMOL GE HEALTHCARE LIMITED (GB) 2018-09-07 WO disclosed
EP-3368518-A1 METHOD FOR PRODUCING FLUTEMETAMOL GE Healthcare Limited (GB) 2018-09-05 EP disclosed
US-20180112098-A1 IMPROVED COATING SYSTEMS, USE THEREOF FOR COATING COMPONENTS AND THUS COATED COMPONENTS FOR WIND POWER PLANTS MANKIEWICZ GEBR. & CO. GMBH & CO. KG (DE) 2018-04-26 US disclosed
US-20180100069-A1 IMPROVED COATING SYSTEMS, USE THEREOF FOR COATING COMPONENTS AND THUS COATED COMPONENTS FOR AGRICULTURAL AND CONSTRUCTION MACHINES MANKIEWICZ GEBR. & CO. GMBH & CO. KG (DE) 2018-04-12 US disclosed
US-20180094143-A1 IMPROVED COATING SYSTEMS, USE THEREOF FOR COATING COMPONENTS AND COMPONENTS COATED THEREWITH FOR RAIL VEHICLES AND AIRCRAFTS MANKIEWICZ GEBR. & CO. GMBH & CO. KG (DE) 2018-04-05 US disclosed
WO-2018022603-A1 METHODS OF MAKING 18F-LABELED PRECURSORS AND PEPTIDES, LABELED C-MET BINDING PEPTIDES, AND METHODS OF USE THEREOF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2018-02-01 WO disclosed
WO-2017214470-A1 IMPROVED SYNTHESIS OF THE RADIOLABELED PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA) INHIBITOR [18F]DCFPyL THE JOHNS HOPKINS UNIVERSITY (US) 2017-12-14 WO disclosed
US-9839701-B2 Aromatic amino acid derivative and positron emission topography (PET) probe using the same OSAKA UNIVERSITY (JP) 2017-12-12 US disclosed
EP-2810926-B1 METHOD FOR PREPARING FLUORINE-18 ELUENT WITH ADJUSTED PH, AND METHOD FOR LABELLING FLUORINE-18 USING SAME ASAN FOUND (KR) 2017-06-21 EP disclosed
WO-2017071980-A1 METHOD FOR PRODUCING FLUTEMETAMOL GE HEALTHCARE LIMITED (GB) 2017-05-04 WO disclosed
WO-2017027870-A1 TRIAZOLE CONJUGATED UREAS, THIOUREAS, CARBAMATES, AND \"REVERSED\" CARBAMATES FOR PSMA-TARGETED IMAGING AGENTS AND USES THEREOF THE JOHNS HOPKINS UNIVERSITY (US) 2017-02-16 WO disclosed
US-20160095946-A1 LABELLED CARBOXYLIC ACIDS AND THEIR USES IN MOLECULAR IMAGING IMPERIAL INNOVATIONS LIMITED (GB) 2016-04-07 US disclosed
WO-2016045035-A1 METHOD FOR PREPARING GRAPHENE 深圳粤网节能技术服务有限公司 2016-03-31 WO disclosed
EP-2994169-A1 LABELLED CARBOXYLIC ACIDS AND THEIR USES IN MOLECULAR IMAGING Imperial Innovations Ltd (GB) 2016-03-16 EP disclosed
WO-2016033190-A1 RADIOTRACER COMPOUNDS EISAI, INC. (JP) 2016-03-03 WO disclosed
US-20160038620-A1 AROMATIC AMINO ACID DERIVATIVE AND POSITRON EMISSION TOPOGRAPHY (PET) PROBE USING THE SAME NARD INSTITUTE, LTD. (JP) 2016-02-11 US disclosed
EP-2957556-A1 AROMATIC AMINO ACID DERIVATIVE AND POSITRON EMISSION TOPOGRAPHY (PET) PROBE UTILIZING SAME Osaka University (JP) 2015-12-23 EP disclosed
EP-2400992-B1 METHODS AND COMPOSITIONS FOR PROTEIN LABELLING GENENTECH INC (US) 2015-07-22 EP disclosed
US-20150045548-A1 METHOD FOR PREPARING FLUORINE-18 ELUENT WITH ADJUSTED PH, AND METHOD FOR LABELLING FLUORINE-18 USING SAME THE ASAN FOUNDATION (KR) 2015-02-12 US disclosed
EP-2810926-A1 METHOD FOR PREPARING FLUORINE-18 ELUENT WITH ADJUSTED PH, AND METHOD FOR LABELLING FLUORINE-18 USING SAME The Asan Foundation (KR) 2014-12-10 EP disclosed
US-8865122-B2 Methods and compositions for protein labelling GENENTECH, INC. (US) 2014-10-21 US disclosed
EP-2700635-A1 5-Trifluoromethylpyrazole amides having herbicidal activity BASF SE (DE) 2014-02-26 EP disclosed
EP-2700634-A1 5-difluoromethylpyrazole amides having herbicidal activity BASF SE (DE) 2014-02-26 EP disclosed
US-20130216475-A1 METHODS AND COMPOSITIONS FOR PROTEIN LABELLING GENENTECH, INC. (US) 2013-08-22 US disclosed
US-8435488-B2 Methods and compositions for protein labelling GENENTECH, INC. (US) 2013-05-07 US disclosed
US-20120097549-A1 ELECTROCHEMICAL CELL AND METHOD FOR SEPARATING CARRIER-FREE 18F-FROM A SOLUTION ON AN ELECTRODE FORSCHUNGSZENTRUM JUELICH GMBH (DE) 2012-04-26 US disclosed
US-20120093726-A1 Radiolabeled Fluorine Derivatives of Methionine CRC FOR BIOMEDICAL IMAGING DEVELOPMENT LTD. (AU) 2012-04-19 US disclosed
EP-2411360-A1 RADIOLABELED FLUORINE DERIVATIVES OF METHIONINE CRC For Biomedical Imaging Development Ltd (AU) 2012-02-01 EP disclosed
EP-2400992-A1 METHODS AND COMPOSITIONS FOR PROTEIN LABELLING Genentech, Inc. (US) 2012-01-04 EP disclosed
US-7807837-B2 Scalable synthesis of imidazole derivatives JANSSEN PHARMACEUTICA NV (BE) 2010-10-05 US disclosed
WO-2010108210-A1 RADIOLABELED FLUORINE DERIVATIVES OF METHIONINE CRC FOR BIOMEDICAL IMAGING DEVELOPMENT LTD (AU) 2010-09-30 WO disclosed
WO-2010099273-A1 METHODS AND COMPOSITIONS FOR PROTEIN LABELLING GENENTECH, INC. (US) 2010-09-02 WO disclosed
US-20100221176-A1 METHODS AND COMPOSITIONS FOR PROTEIN LABELLING GENENTECH, INC. 2010-09-02 US disclosed
US-20090143591-A1 SCALABLE SYNTHESIS OF IMIDAZOLE DERIVATIVES JANSSEN PHARMACEUTICA NV (BE) 2009-06-04 US disclosed
US-7507756-B2 Scalable synthesis of imidazole derivatives JANSSEN PHARMACEUTICA N.V. (BE) 2009-03-24 US disclosed
EP-1373218-B9 IMIDAZOLYL DERIVATIVES USEFUL AS HISTAMINE H3 RECEPTOR LIGANDS ORTHO MCNEIL JANSSEN PHARM (US) 2008-12-03 EP disclosed
EP-1373218-B1 IMIDAZOLYL DERIVATIVES USEFUL AS HISTAMINE H3 RECEPTOR LIGANDS ORTHO MCNEIL PHARM INC (US) 2008-01-09 EP disclosed
US-7265135-B2 2-oxy, 2-amino, and 2-thio-imidazole compounds ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2007-09-04 US disclosed
US-20070014725-A1 Conjugates of macrocyclic metal complexes with biomolecules and their use for the production of agents for NMR diagnosis and radiodiagnosis as well as radiotherapy SCHERING AG (DE) 2007-01-18 US disclosed
US-7164016-B2 Macrocyclic metal complexes and their use for the production of conjugates with biomolecules SCHERING AG (DE) 2007-01-16 US disclosed
US-20070009442-A1 Macrocyclic metal complexes and their use for the production of conjugates with biomolecules SCHERING AG (DE) 2007-01-11 US disclosed
US-20050250948-A1 Scalable synthesis of imidazole derivatives JANSSEN PHARMACEUTICA N.V. (BE) 2005-11-10 US disclosed
US-6919475-B2 Protected tyrosine derivatives, method for the production thereof and use of the same for producing o-(2-[18f]-fluoroethyl)-l-tyrosine Forschungszentrum Jülich GmbH (DE) 2005-07-19 US disclosed
US-20040192954-A1 Protected tyrosine derivatives, method for the production thereof and use of the same for producing o-(2-[18f]-fluoroethyl)-l-tyrosine FORSCHUNGSZENTRUM GMBH (DE) 2004-09-30 US disclosed
US-20040147577-A1 Heterocyclic compounds BOGENSTAETTER MICHAEL (GB) 2004-07-29 US disclosed
US-20030206865-A1 Conjugates of macrocyclic metal complexes with biomolecules and their use for the production of agents for NMR diagnosis and radiodiagnosis as well as radiotherapy SCHERING AG (DE) 2003-11-06 US disclosed
US-20030108486-A1 Macrocyclic metal complexes and their use for the production of conjugates with biomolecules SCHERING AG (DE) 2003-06-12 US disclosed
US-20020198237-A1 Heterocyclic compounds ORTHO MCNEIL PHARMACEUTICAL, INC. 2002-12-26 US disclosed
US-5756683-A SULFONYLUREA HERBICIDES NOVARTIS FINANCE CORPORATION (US) 1998-05-26 US disclosed
US-5693599-A Flux washing agent MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1997-12-02 US disclosed
US-5563074-A ANTIBODY SPECIFIC TO SULFONYLUREA HERBICIDE CIBA-GEIGY CORPORATION (US) 1996-10-08 US disclosed
US-5516938-A SULFONYLUREA LINKING COMPONENT CIBA-GEIGY CORPORATION (US) 1996-05-14 US disclosed
US-5516928-A REACTION OF ISOPHORONE AND HYDROGEN CYANIDE USING QUATERNARY AMMONIUM CATALYST BASF AKTIENGESELLSCHAFT (DE) 1996-05-14 US disclosed
US-5359135-A Detection in soil, water, air by preferential affinity to monoclonal antibodies CIBA-GEIGY CORPORATION (US) 1994-10-25 US disclosed
US-5359135-A Detection in soil, water, air by preferential affinity to monoclonal antibodies CIBA-GEIGY CORPORATION (US) 1994-10-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (48 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210322582-A1 RADIOACTIVE IMIDAZOTHIADIAZOLE DERIVATIVE COMPOUND CA9, CA4, CA14 SLC22A1 2306/4885SLC22A2 2859/4885ALDH1A1 3630/4885
US-20030108486-A1 Macrocyclic metal complexes and their use for the production of conjugates with biomolecules CA13, MPI, CA14 SLC22A1 912/4885SLC22A2 868/4885ALDH1A1 3392/4885
US-20260124326-A1 USE OF CYCLODEXTRINS AS A RADIOSTABILIZER SLC7A11, BTD, PGD SLC22A1 494/4885SLC22A2 907/4885ALDH1A1 778/4885
US-10759760-B2 Precursors for radiofluorination QRFPR, SSTR3, IGF1R SLC22A1 2877/4885SLC22A2 3032/4885ALDH1A1 4360/4885
US-20210023558-A1 SOLID PHASE EXTRACTION PNN, PDXK, TYMP SLC22A1 3282/4885SLC22A2 3263/4885ALDH1A1 2504/4885
US-11078166-B2 Triazole conjugated ureas, thioureas, carbamates, and reversed carbamates for PSMA-targeted imaging agents and uses thereof PAICS, FOLH1, UTS2R SLC22A1 2887/4885SLC22A2 3175/4885ALDH1A1 3174/4885
US-20120093726-A1 Radiolabeled Fluorine Derivatives of Methionine BHMT2, MGMT, AHCY SLC22A1 1057/4885SLC22A2 1155/4885ALDH1A1 1944/4885
US-20160095946-A1 LABELLED CARBOXYLIC ACIDS AND THEIR USES IN MOLECULAR IMAGING PSAT1, SLC25A1, SLC16A7 SLC22A1 176/4885SLC22A2 126/4885ALDH1A1 2719/4885
US-20070014725-A1 Conjugates of macrocyclic metal complexes with biomolecules and their use for the production of agents for NMR diagnosis and radiodiagnosis as well as radiotherapy CA13, CA14, CA12 SLC22A1 505/4885SLC22A2 506/4885ALDH1A1 2758/4885
US-20040192954-A1 Protected tyrosine derivatives, method for the production thereof and use of the same for producing o-(2-[18f]-fluoroethyl)-l-tyrosine TH, TYR, TYRO3 SLC22A1 2489/4885SLC22A2 3060/4885ALDH1A1 1316/4885
US-20190184039-A1 LABELLED CARBOXYLIC ACIDS AND THEIR USES IN MOLECULAR IMAGING SLC25A1, DNPEP, CA3 SLC22A1 174/4885SLC22A2 118/4885ALDH1A1 2358/4885
US-20210017098-A1 STABILISED RADIOLABELLING REACTION PDXK, MPI, PAICS SLC22A1 2484/4885SLC22A2 2711/4885ALDH1A1 2671/4885
US-20250041859-A1 SOLID PHASE EXTRACTION PNN, PDXK, TYMP SLC22A1 3282/4885SLC22A2 3263/4885ALDH1A1 2504/4885
US-20100221176-A1 METHODS AND COMPOSITIONS FOR PROTEIN LABELLING RAB5IF, RPS27A, PSMA6 SLC22A1 3158/4885SLC22A2 3303/4885ALDH1A1 4242/4885
US-20150045548-A1 METHOD FOR PREPARING FLUORINE-18 ELUENT WITH ADJUSTED PH, AND METHOD FOR LABELLING FLUORINE-18 USING SAME PHF8, AFF1, F8 SLC22A1 897/4885SLC22A2 1107/4885ALDH1A1 3452/4885
US-20190055207-A1 Method for Producing Flutemetamol ADRB3, ADRB1, ADRB2 SLC22A1 3444/4885SLC22A2 3666/4885ALDH1A1 3367/4885
US-20090143591-A1 SCALABLE SYNTHESIS OF IMIDAZOLE DERIVATIVES ABL1, NOS2, FLT3 SLC22A1 4542/4885SLC22A2 4413/4885ALDH1A1 2343/4885
US-20030206865-A1 Conjugates of macrocyclic metal complexes with biomolecules and their use for the production of agents for NMR diagnosis and radiodiagnosis as well as radiotherapy CA13, CA14, CA12 SLC22A1 505/4885SLC22A2 506/4885ALDH1A1 2758/4885
US-11565257-B2 Stabilized radiolabelling reaction PDXK, MPI, PAICS SLC22A1 2855/4885SLC22A2 3116/4885ALDH1A1 2933/4885
US-11053200-B2 Precursors for radiofluorination QRFPR, SSTR3, IGF1R SLC22A1 2877/4885SLC22A2 3032/4885ALDH1A1 4360/4885
US-10947197-B2 Synthesis of the radiolabeled prostate-specific membrane antigen (PSMA) inhibitor [18F]DCFPyL FOLH1, KLK3, BPHL SLC22A1 738/4885SLC22A2 900/4885ALDH1A1 2011/4885
US-20240350683-A1 PREPARATION OF A PH-ADJUSTED ASCORBIC ACID SOLUTION PROC, CYP27B1, TTPA SLC22A1 679/4885SLC22A2 666/4885ALDH1A1 224/4885
US-20220409752-A1 USE OF CYCLODEXTRINS AS A RADIOSTABILIZER SLC7A11, TBCA, GYPA SLC22A1 313/4885SLC22A2 459/4885ALDH1A1 1366/4885
US-20220118117-A1 MODULATORS OF METABOTROPIC GLUTAMATE RECEPTOR 4 GRM2, GRM4, GRM1 SLC22A1 408/4885SLC22A2 367/4885ALDH1A1 4206/4885
US-20200062724-A1 A PROCESS FOR PRODUCING FLUTAMETAMOL ADRB3, ADRB1, PFAS SLC22A1 3411/4885SLC22A2 3802/4885ALDH1A1 1241/4885
US-20050250948-A1 Scalable synthesis of imidazole derivatives ABL1, NOS2, FLT3 SLC22A1 4542/4885SLC22A2 4413/4885ALDH1A1 2343/4885
US-10472338-B2 Method for producing [18F]flutemetamol ADRB3, ADRB1, ADRB2 SLC22A1 3163/4885SLC22A2 3414/4885ALDH1A1 2641/4885
US-10894779-B2 Process for producing flutametamol ADRB3, ADRB1, ADRA1B SLC22A1 3363/4885SLC22A2 3737/4885ALDH1A1 1386/4885
US-20190151483-A1 METHODS OF MAKING 18F-LABELED PRECURSORS AND PEPTIDES, LABELED C-MET BINDING PEPTIDES, AND METHODS OF USE THEREOF MET, MYCBP, METTL14 SLC22A1 810/4885SLC22A2 883/4885ALDH1A1 3909/4885
US-20020198237-A1 Heterocyclic compounds HRH2, HRH4, HRH1 SLC22A1 4331/4885SLC22A2 4237/4885ALDH1A1 1526/4885
US-20220055991-A1 SYNTHESIS OF THE RADIOLABELED PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA) INHIBITOR [18F]DCFPYL FOLH1, KLK3, BPHL SLC22A1 738/4885SLC22A2 900/4885ALDH1A1 2011/4885
US-20230120841-A1 CASSETTE FOR STABILISED RADIOLABELLING REACTION PAICS, MPI, PDXK SLC22A1 1309/4885SLC22A2 1699/4885ALDH1A1 2038/4885
US-20160038620-A1 AROMATIC AMINO ACID DERIVATIVE AND POSITRON EMISSION TOPOGRAPHY (PET) PROBE USING THE SAME SLC7A1, SLC43A1, LATS1 SLC22A1 64/4885SLC22A2 125/4885ALDH1A1 2352/4885
US-20250312494-A1 METHOD FOR PREPARING AN [18F] RADIOLABELLED COMPOUND WITH LOW WATER CONTENT DURING LABELLING STEP AQP1, AQP3, TMEM14C SLC22A1 2282/4885SLC22A2 2410/4885ALDH1A1 3162/4885
US-20190177275-A1 IMPROVED SYNTHESIS OF THE RADIOLABELED PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA) INHIBITOR [18F]DCFPYL KLK3, FOLH1, BPHL SLC22A1 1018/4885SLC22A2 1172/4885ALDH1A1 2167/4885
US-20070009442-A1 Macrocyclic metal complexes and their use for the production of conjugates with biomolecules CA13, MPI, CA14 SLC22A1 912/4885SLC22A2 868/4885ALDH1A1 3392/4885
US-10821194-B2 Labelled carboxylic acids and their uses in molecular imaging SLC25A1, DNPEP, CA3 SLC22A1 174/4885SLC22A2 118/4885ALDH1A1 2358/4885
US-20130216475-A1 METHODS AND COMPOSITIONS FOR PROTEIN LABELLING RAB5IF, RPS27A, PSMA6 SLC22A1 3158/4885SLC22A2 3303/4885ALDH1A1 4242/4885
US-10392344-B2 Method for preparing fluorine-18 eluent with adjusted PH, and method for labelling fluorine-18 using same PHF8, AFF1, F8 SLC22A1 897/4885SLC22A2 1107/4885ALDH1A1 3452/4885
US-20040147577-A1 Heterocyclic compounds HRH2, HRH4, HRH1 SLC22A1 4331/4885SLC22A2 4237/4885ALDH1A1 1526/4885
US-20190263756-A1 PRECURSORS FOR RADIOFLUORINATION QRFPR, SSTR3, IGF1R SLC22A1 2877/4885SLC22A2 3032/4885ALDH1A1 4360/4885
US-20250162993-A1 SYNTHESIS OF THE RADIOLABELED PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA) INHIBITOR [18F]DCFPYL FOLH1, KLK3, BPHL SLC22A1 766/4885SLC22A2 938/4885ALDH1A1 1969/4885
US-20240366808-A1 METHOD FOR PREPARING AN [18F] RADIOLABELLED COMPOUND WITH LOW WATER CONTENT DURING LABELLING STEP AQP1, AQP3, TMEM14C SLC22A1 2375/4885SLC22A2 2485/4885ALDH1A1 3147/4885
US-20190225589-A1 TRIAZOLE CONJUGATED UREAS, THIOUREAS, CARBAMATES, AND REVERSED CARBAMATES FOR PSMA-TARGETED IMAGING AGENTS AND USES THEREOF PAICS, FOLH1, UTS2R SLC22A1 2887/4885SLC22A2 3175/4885ALDH1A1 3174/4885
US-12527884-B2 Use of cyclodextrins as a radiostabilizer BTD, SLC7A11, PGD SLC22A1 501/4885SLC22A2 884/4885ALDH1A1 898/4885
US-20200165204-A1 PRECURSORS FOR RADIOFLUORINATION QRFPR, SSTR3, IGF1R SLC22A1 2877/4885SLC22A2 3032/4885ALDH1A1 4360/4885
US-11851407-B2 Synthesis of the radiolabeled prostate-specific membrane antigen (PSMA) inhibitor [18F]DCFPYL FOLH1, KLK3, BPHL SLC22A1 738/4885SLC22A2 900/4885ALDH1A1 2011/4885
US-12162009-B2 Solid phase purification PDXK, PNN, TYMP SLC22A1 3112/4885SLC22A2 3118/4885ALDH1A1 1993/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.