SCHEMBL2118529

SCHEMBL2118529

Cn1c(N)nc2[nH]cnc2c1=S

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
TP53 P04637 2/20 0.36
HPGD P15428 2/20 0.36
PTGS1 P23219 2/20 0.36
HBB P68871 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
KDM4E B2RXH2 1/20 0.36
ADORA3 P0DMS8 2/20 0.34
USP2 O75604 1/20 0.34
MAPK3 P27361 1/20 0.34
XDH P47989 1/20 0.34
PAX8 Q06710 1/20 0.34
BTK Q06187 1/20 0.33
ATAD2 Q6PL18 1/20 0.31
LMNA P02545 1/20 0.30
CYP1A2 P05177 1/20 0.30
MAPT P10636 1/20 0.30
ADORA2A P29274 2/20 0.30
ADORA2B P29275 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20866 0.79 ATAD2 (0.41) ALDH1A1HPGDKDM4EADORA3ATAD2
SCHEMBL2118527 0.72 PDPK1 (0.44) ALDH1A1TP53HPGDPTGS1HBB
SCHEMBL26948743 0.72 ADORA2B (0.42) ALDH1A1TP53HPGDPTGS1HBB
Trifluoroacetic Acid SCHEMBL2300169 0.69 KDM4E (0.35) ALDH1A1HPGDKDM4EADORA3ATAD2
SCHEMBL2117280 0.69 ALDH1A1 (0.39) ALDH1A1TP53HPGDPTGS1HBB
SCHEMBL15347874 0.69 CHRNB2 (0.39) ALDH1A1ADORA3BTKATAD2LMNA
SCHEMBL667794 0.67 PDE4A (0.49) HPGDADORA3ADORA2AADORA2BPDE4A
SCHEMBL10597939 0.67 PNP (0.33) ADORA3ATAD2LMNACYP1A2MAPT
SCHEMBL8886026 0.67 PNP (0.35) ADORA3ATAD2LMNACYP1A2MAPT
SCHEMBL3259641 0.67 PNP (0.35) ALDH1A1ADORA3ATAD2LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 271 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026103877-A1 LIPID COMPOUND AND LIPID NANOPARTICLE COMPOSITION 中生复诺健生物科技(上海)有限公司 2026-05-21 WO disclosed
US-20260130987-A1 VACCINATION AGAINST PNEUMOCCOCAL AND COVID-19 INFECTIONS PFIZER INC. (US) 2026-05-14 US disclosed
US-20260109977-A1 MODIFIED RNA FOR INCREASING PROTEIN EXPRESSION TRILINK BIOTECHNOLOGIES, LLC (US) 2026-04-23 US disclosed
EP-4720094-A1 MUTATED FRAGMENT OF VZV GLYCOPROTEIN E Suzhou Abogen Biosciences Co., Ltd. (CN) 2026-04-08 EP disclosed
US-12594242-B2 Lipid compounds and lipid nanoparticle compositions Suzhou Abogen Biosciences Co., Ltd. (CN) 2026-04-07 US disclosed
US-20260078082-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX INC (US) 2026-03-19 US disclosed
US-20260069549-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX INC (US) 2026-03-12 US disclosed
US-20260061042-A1 POLYNUCLEOTIDE COMPOSITIONS AND USES THEREOF PFIZER (US) 2026-03-05 US disclosed
US-20250387764-A1 COAXIAL FLOW DEVICE FOR NANOPARTICLE PREPARATION AND MANUFACTURING EQUIPMENT INCLUDING SUCH DEVICE PFIZER INC. (US) 2025-12-25 US disclosed
US-20250382323-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR DETECTING NUCLEOTIDES AXBIO INC (US) 2025-12-18 US disclosed
WO-2017066797-A1 TRINUCLEOTIDE MRNA CAP ANALOGS MODERNATX, INC. (US) 2017-04-20 WO disclosed
WO-2017066781-A1 MRNA CAP ANALOGS WITH MODIFIED PHOSPHATE LINKAGE MODERNATX, INC. (US) 2017-04-20 WO disclosed
WO-2017066789-A1 MRNA CAP ANALOGS WITH MODIFIED SUGAR MODERNATX, INC. (US) 2017-04-20 WO disclosed
WO-2017049245-A2 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX, INC. (US) 2017-03-23 WO disclosed
WO-2017049286-A1 POLYNUCLEOTIDES CONTAINING A MORPHOLINO LINKER MODERNA THERAPEUTICS, INC. (US) 2017-03-23 WO disclosed
WO-2017049275-A2 POLYNUCLEOTIDES CONTAINING A STABILIZING TAIL REGION MODERNA THERAPEUTICS, INC. (US) 2017-03-23 WO disclosed
WO-2015196118-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF MODERNA THERAPEUTICS, INC. (US) 2015-12-23 WO disclosed
US-20150119351-A1 THERAPY OF TUMORS AND INFECTIOUS AGENTS DEFICIENT IN METHYLTHIOADENOSINE PHOSPHORYLASE LUBIN ADAM (US) 2015-04-30 US disclosed
US-8796241-B2 Therapy of tumors and infectious agents deficient in methylthioadenosine phosphorylase LUBIN ADAM (US) 2014-08-05 US disclosed
US-20120094947-A1 METHOD FOR THE SELECTIVE THERAPY OF DISEASE LUBIN ADAM (US) 2012-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109977-A1 MODIFIED RNA FOR INCREASING PROTEIN EXPRESSION RNGTT, RNMT, UPF1 ALDH1A1 4457/4885TP53 2406/4885HPGD 4612/4885
US-20260130987-A1 VACCINATION AGAINST PNEUMOCCOCAL AND COVID-19 INFECTIONS SARS1, CD14, PYCARD ALDH1A1 4675/4885TP53 1086/4885HPGD 1971/4885
US-12594242-B2 Lipid compounds and lipid nanoparticle compositions NPC1, NPC1L1, PLIN3 ALDH1A1 4206/4885TP53 2179/4885HPGD 4111/4885
US-20260078082-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS PHOSPHO1, LIPC, SDCBP ALDH1A1 4429/4885TP53 771/4885HPGD 4496/4885
US-20260069549-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS SIN3A, PLIN3, MSR1 ALDH1A1 4755/4885TP53 1151/4885HPGD 4041/4885
US-20250387764-A1 COAXIAL FLOW DEVICE FOR NANOPARTICLE PREPARATION AND MANUFACTURING EQUIPMENT INCLUDING SUCH DEVICE POLRMT, MTREX, PHAX ALDH1A1 3073/4885TP53 190/4885HPGD 1064/4885
US-20260061042-A1 POLYNUCLEOTIDE COMPOSITIONS AND USES THEREOF SELP, LNPEP, NOP2 ALDH1A1 4401/4885TP53 321/4885HPGD 4229/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.