Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 4/20 | 0.61 |
| ▸ | SLC6A4 known ✓ | P31645 | 4/20 | 0.61 |
| ▸ | SLC6A3 known ✓ | Q01959 | 4/20 | 0.61 |
| ▸ | SIGMAR1 known ✓ | Q99720 | 6/20 | 0.55 |
| ▸ | HTR1A known ✓ | P08908 | 1/20 | 0.50 |
| ▸ | HTR1D known ✓ | P28221 | 1/20 | 0.50 |
| ▸ | HTR1B known ✓ | P28222 | 1/20 | 0.50 |
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C known ✓ | P28335 | 1/20 | 0.50 |
| ▸ | HTR1E known ✓ | P28566 | 1/20 | 0.50 |
| ▸ | HTR7 known ✓ | P34969 | 1/20 | 0.50 |
| ▸ | HTR2B known ✓ | P41595 | 1/20 | 0.50 |
| ▸ | HTR3A known ✓ | P46098 | 1/20 | 0.50 |
| ▸ | HTR5A known ✓ | P47898 | 1/20 | 0.50 |
| ▸ | HTR6 known ✓ | P50406 | 1/20 | 0.50 |
| ▸ | HRH3 known ✓ | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | KCNH2 known ✓ | Q12809 | 1/20 | 0.46 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4804093 | 0.98 | SLC6A2 (0.62) | SLC6A2SLC6A4SLC6A3PYCR1SIGMAR1 | |
| Propene SCHEMBL2169931 | 0.91 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3PYCR1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL5913932 | 0.82 | HTR2A (0.46) | SLC6A2SLC6A4SLC6A3PYCR1SIGMAR1 | |
| SCHEMBL7079099 | 0.81 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3PYCR1SIGMAR1 | |
| SCHEMBL19576554 | 0.81 | PYCR1 (0.56) | SLC6A2SLC6A4SLC6A3PYCR1SIGMAR1 | |
| SCHEMBL18901128 | 0.81 | PYCR1 (0.56) | SLC6A2SLC6A4SLC6A3PYCR1SIGMAR1 | |
| SCHEMBL23357811 | 0.79 | HRH3 (0.45) | SLC6A2SLC6A4SLC6A3PYCR1SIGMAR1 | |
| SCHEMBL15051655 | 0.79 | HTR7 (0.47) | SLC6A2SLC6A4SLC6A3PYCR1SIGMAR1 | |
| SCHEMBL23992712 | 0.79 | HTR1A (0.47) | SLC6A2SLC6A4SLC6A3PYCR1SIGMAR1 | |
| SCHEMBL8290709 | 0.79 | TAAR1 (0.47) | SLC6A2SLC6A4SLC6A3PYCR1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1411913-A4 | ANTIMICROBIAL NANOEMULSION COMPOSITIONS AND METHODS | UNIV MICHIGAN (US) | 2009-09-02 | — | — | EP | claimed |
| US-7033511-B2 | Sustained water treatment in dental equipment | A-DEC, INC. (US) | 2006-04-25 | — | — | US | claimed |
| EP-1557088-A1 | Sustained water treatment in dental equipment | A-DEC, INC. (US) | 2005-07-27 | — | — | EP | claimed |
| US-20050155937-A1 | Sustained water treatment in dental equipment | A-DEC, INC. | 2005-07-21 | — | — | US | claimed |
| EP-1411913-A1 | ANTIMICROBIAL NANOEMULSION COMPOSITIONS AND METHODS | The Regents of the University of Michigan (US) | 2004-04-28 | — | — | EP | claimed |
| WO-2003000243-A1 | ANTIMICROBIAL NANOEMULSION COMPOSITIONS AND METHODS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2003-01-03 | — | — | WO | claimed |
| EP-3653303-B1 | PIPETTE TIP RACK | BIOTIX INC (US) | 2025-02-26 | — | — | EP | disclosed |
| US-20250024837-A1 | PESTICIDE SYSTEM | BANISH, MICHELE | 2025-01-23 | — | — | US | disclosed |
| US-12201987-B2 | Pipette tip rack | BIOTIX, INC. (US) | 2025-01-21 | — | — | US | disclosed |
| EP-4376673-B1 | FILAMENTS FOR ORAL CARE IMPLEMENTS | UNILEVER IP HOLDINGS B V (NL) | 2025-01-01 | — | — | EP | disclosed |
| CN-118042960-A | Filaments for oral care implements | 联合利华知识产权控股有限公司 | 2024-05-14 | — | — | CN | disclosed |
| US-20240074434-A1 | COMPOSITION INCLUDING EFFERVESCENT AGENTS, BIOSTIMULANT, NUTRIENT, AND PESTICIDE | ROBBINS JEFFREY HANSON (US) | 2024-03-07 | — | — | US | disclosed |
| US-20240065262-A1 | COMPOSITION INCLUDING EFFERVESCENT AGENTS, BIOSTIMULANT, NUTRIENT, AND PESTICIDE | ROBBINS JEFFREY HANSON (US) | 2024-02-29 | — | — | US | disclosed |
| US-20050155937-A1 | Sustained water treatment in dental equipment | A-DEC, INC. | 2005-07-21 | — | — | US | disclosed |
| EP-1458419-B1 | ANTIMICROBIAL CONTACT LENS CASE | NOVARTIS AG (CH) | 2005-05-04 | — | — | EP | disclosed |
| EP-1458419-A1 | ANTIMICROBIAL CONTACT LENS CASE | Novartis AG (CH) | 2004-09-22 | — | — | EP | disclosed |
| US-20030176530-A1 | Antimicrobial contact lens case | LINDLEY KAREN FRANCES (US) | 2003-09-18 | — | — | US | disclosed |
| WO-2003049776-A1 | ANTIMICROBIAL CONTACT LENS CASE | NOVARTIS AG (CH) | 2003-06-19 | — | — | WO | disclosed |
| US-4248633-A | Universal copper-plating solution | U.S. PHILIPS CORPORATION (US) | 1981-02-03 | — | — | US | disclosed |
| US-4146573-A | RED MUD TREATMENT | NALCO CHEMICAL COMPANY (US) | 1979-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250024837-A1 | PESTICIDE SYSTEM | ACHE, PFAS, FPGS | SLC6A2 4774/4885SLC6A4 4377/4885SLC6A3 4590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.