Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL113460 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL8982942 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL11586598 | 0.80 | CA2 (0.43) | CA2USP2ALOX15MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11584278 | 0.80 | — | — | |
| Phosphoric Acid SCHEMBL30854804 | 0.75 | CA2 (0.46) | CA2USP2ALOX15MEN1KMT2A | |
| SCHEMBL4914754 | 0.75 | — | — | |
| SCHEMBL3270647 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL11595910 | 0.74 | — | — | |
| SCHEMBL13303865 | 0.72 | — | — | |
| SCHEMBL11248631 | 0.72 | FDPS (0.39) | CA2USP2ALOX15MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4098819-A | PROCESS FOR THE PRODUCTION OF PHOSPHORIC ACID-DIMETHYLAMIDE-DICHLORIDE OR PHOSPHORIC ACID-BIS-(DIMETHYLAMIDE)-CHLORIDE | WACKER-CHEMIE GMBH (DE) | 1978-07-04 | — | — | US | claimed |
| EP-4121476-A1 | PROCESS FOR PRODUCING POLYETHER CARBONATE POLYOLS | Covestro Deutschland AG (DE) | 2023-01-25 | — | — | EP | disclosed |
| EP-4118130-A1 | PROCESS FOR PREPARING POLYETHER CARBONATE POLYOLS | Covestro Deutschland AG (DE) | 2023-01-18 | — | — | EP | disclosed |
| EP-4069763-A1 | PROCESS FOR PRODUCING POLYETHER CARBONATE POLYOLS | Covestro Intellectual Property GmbH & Co. KG (DE) | 2022-10-12 | — | — | EP | disclosed |
| EP-3911690-B1 | PROCESS FOR THE PREPARATION OF DIOL | COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) | 2022-07-13 | — | — | EP | disclosed |
| EP-3844205-B1 | METHOD FOR THE SEPARATION OF GASEOUS COMPONENTS | COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) | 2022-06-01 | — | — | EP | disclosed |
| EP-3810674-B1 | METHOD FOR THE PREPARATION OF POLYOL | COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) | 2022-04-20 | — | — | EP | disclosed |
| EP-3911690-A1 | PROCESS FOR PRODUCING DIOL | Covestro Intellectual Property GmbH & Co. KG (DE) | 2021-11-24 | — | — | EP | disclosed |
| EP-3810674-A1 | PROCESS FOR PRODUCING POLYOL | Covestro Intellectual Property GmbH & Co. KG (DE) | 2021-04-28 | — | — | EP | disclosed |
| WO-2020148161-A1 | PROCESS FOR PRODUCING DIOL | COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) | 2020-07-23 | — | — | WO | disclosed |
| US-20080280965-A1 | Novel tetrahydrocarbazole derivatives having improved biological action and improved solubility as ligands of G-protein coupled receptors (GPCPs) | KLAUS PAULINI, ET AL. | 2008-11-13 | — | — | US | disclosed |
| US-7375127-B2 | Tetrahydrocarbazole derivatives having improved biological action and improved solubility as ligands of G-protein coupled receptors (GPCRs) | AE ZENTARIS GMBH (DE) | 2008-05-20 | — | — | US | disclosed |
| US-20060014818-A1 | Novel tetrahydrocarbazole derivatives having improved biological action and improved solubility as ligands of G-protein coupled receptors (GPCRs) | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT | 2006-01-19 | — | — | US | disclosed |
| US-6103745-A | USEFUL FOR HIGH FUNGICIDAL, INSECTICIDAL AND ACARICIDAL ACTIVITY | BAYER AKTIENGESELLSCHAFT (DE) | 2000-08-15 | — | — | US | disclosed |
| US-5932605-A | Substituted benzimidazoles for pest control | BAYER AKTIENGESELLSCHAFT (DE) | 1999-08-03 | — | — | US | disclosed |
| US-5731300-A | FUNGICIDES, INSECTICIDES, ACARICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-03-24 | — | — | US | disclosed |
| US-4098819-A | PROCESS FOR THE PRODUCTION OF PHOSPHORIC ACID-DIMETHYLAMIDE-DICHLORIDE OR PHOSPHORIC ACID-BIS-(DIMETHYLAMIDE)-CHLORIDE | WACKER-CHEMIE GMBH (DE) | 1978-07-04 | — | — | US | disclosed |
| US-4098819-A | PROCESS FOR THE PRODUCTION OF PHOSPHORIC ACID-DIMETHYLAMIDE-DICHLORIDE OR PHOSPHORIC ACID-BIS-(DIMETHYLAMIDE)-CHLORIDE | WACKER-CHEMIE GMBH (DE) | 1978-07-04 | — | — | US | disclosed |
| US-4094902-A | Process for the manufacture of phosphoric acid-tris-(dimethylamide) | WACKER-CHEMIE GMBH (DT) | 1978-06-13 | — | — | US | disclosed |
| US-4094902-A | Process for the manufacture of phosphoric acid-tris-(dimethylamide) | WACKER-CHEMIE GMBH (DT) | 1978-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060014818-A1 | Novel tetrahydrocarbazole derivatives having improved biological action and improved solubility as ligands of G-protein coupled receptors (GPCRs) | GPR88, GPR34, GPR35 | CA2 600/4885USP2 2826/4885ALOX15 987/4885 |
| US-20080280965-A1 | Novel tetrahydrocarbazole derivatives having improved biological action and improved solubility as ligands of G-protein coupled receptors (GPCPs) | GPR35, GPR88, GPBAR1 | CA2 521/4885USP2 3798/4885ALOX15 1667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.